A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

Molecular Cell

Volumn 39, Issue 1, 2010, Pages 36-47

  Smogorzewska, Agata ^a,b,c   Desetty, Rohini ^c   Saito, Takamune T ^d   Schlabach, Michael ^a   Lach, Francis P ^c   Sowa, Mathew E ^d   Clark, Alan B ^e   Kunkel, Thomas A ^e   Harper, J Wade ^d   Colaiácovo, Monica P ^d   Elledge, Stephen J ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

DNA; Humdisease

Indexed keywords

CAMPTOTHECIN; ENDONUCLEASE; EXONUCLEASE; FANCONI ANEMIA ASSOCIATED NUCLEASE 1; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA PROTEIN; MISMATCH REPAIR PROTEIN; MITOMYCIN C; PROTEIN EXDL2; PROTEIN MLH1; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; FANCONI ANEMIA; GENE IDENTIFICATION; GENETIC CONSERVATION; GENETIC SCREENING; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; OSTEOSARCOMA CELL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CELL LINE; CROSS-LINKING REAGENTS; DNA DAMAGE; DNA MISMATCH REPAIR; DNA REPAIR; ENDONUCLEASES; EXODEOXYRIBONUCLEASES; EXONUCLEASES; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; GENETIC TESTING; GENOME, HUMAN; HUMANS; MITOMYCIN; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RNA, SMALL INTERFERING;

EID: 77954286076     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.06.023     Document Type: Article

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