메뉴 건너뛰기




Volumn 32, Issue 15, 2004, Pages 4524-4530

The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE CARBAMOYLTRANSFERASE; CARBAMOYL PHOSPHATE SYNTHASE; DIHYDROOROTASE; NUCLEOTIDE; PROTEIN RAD9; PYRIMIDINE; RIBONUCLEOTIDE; CAD TRIFUNCTIONAL ENZYME; CARBAMOYL PHOSPHATE SYNTHASE (GLUTAMINE HYDROLYSING); CELL CYCLE PROTEIN;

EID: 4344675706     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh789     Document Type: Article
Times cited : (22)

References (32)
  • 1
    • 3943107573 scopus 로고    scopus 로고
    • Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
    • Sancar,A, Lindsey-Boltz,L.A., Unsal-Kacmaz,K. and Linn,S. (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem., 73, 39-85.
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 39-85
    • Sancar, A.1    Lindsey-Boltz, L.A.2    Unsal-Kacmaz, K.3    Linn, S.4
  • 2
  • 3
    • 0345564858 scopus 로고    scopus 로고
    • Replication protein A-mediated recruitment and activation of Rad17 complexes
    • Zou,L., Liu,D. and Elledge,S.J. (2003) Replication protein A-mediated recruitment and activation of Rad17 complexes. Proc. Natl Acad. Sci. USA, 100, 13827-13832.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 13827-13832
    • Zou, L.1    Liu, D.2    Elledge, S.J.3
  • 4
    • 4243156107 scopus 로고    scopus 로고
    • Biochemical characterization of DNA damage checkpoint complexes: Clamp loader and clamp complexes with specificity for 5′ recessed DNA
    • Ellison,V. and Stillman,B. (2003) Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5′ recessed DNA. PLoS Biol., 1, E33.
    • (2003) PLoS Biol. , vol.1
    • Ellison, V.1    Stillman, B.2
  • 5
    • 0037418195 scopus 로고    scopus 로고
    • Yeast Rad17/Mec3/Ddc1: A sliding clamp for the DNA damage checkpoint
    • Majka,J. and Burgers,P.M. (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc. Natl Acad. Sci. USA, 100, 2249-2254.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2249-2254
    • Majka, J.1    Burgers, P.M.2
  • 6
    • 1342282903 scopus 로고    scopus 로고
    • Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells
    • Wang,L., Hsu,C.-L., Ni,J., Wang,P.-H., Yeh,S., Keng,P. and Chang,C. (2004) Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells. Mol. Cell. Biol., 24, 2202-2213.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 2202-2213
    • Wang, L.1    Hsu, C.-L.2    Ni, J.3    Wang, P.-H.4    Yeh, S.5    Keng, P.6    Chang, C.7
  • 7
    • 0036241988 scopus 로고    scopus 로고
    • c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage
    • Yoshida,K., Komatsu,K., Wang,H.G. and Kufe,D. (2002) c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. Mol. Cell. Biol.. 22, 3292-3300.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 3292-3300
    • Yoshida, K.1    Komatsu, K.2    Wang, H.G.3    Kufe, D.4
  • 8
    • 0038237433 scopus 로고    scopus 로고
    • Protein kinase C delta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9
    • Yoshida,K., Wang,H.G., Miki,Y. and Kufe,D. (2003) Protein kinase C delta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J., 22, 1431-1441.
    • (2003) EMBO J. , vol.22 , pp. 1431-1441
    • Yoshida, K.1    Wang, H.G.2    Miki, Y.3    Kufe, D.4
  • 10
    • 0018823799 scopus 로고
    • Pyrimidine nucleotide biosynthesis in animals: Genes, enzymes, and regulation of UMP biosynthesis
    • Jones,M.E. (1980) Pyrimidine nucleotide biosynthesis in animals: genes, enzymes, and regulation of UMP biosynthesis. Annu. Rev. Biochem., 49, 253-279.
    • (1980) Annu. Rev. Biochem. , vol.49 , pp. 253-279
    • Jones, M.E.1
  • 11
    • 0023958952 scopus 로고
    • Mapping of catalytic domains and phosphorylation sites in the multifunctional pyrimidine-biosynthetic protein CAD
    • Carrey,E.A. and Hardie,D.G. (1988) Mapping of catalytic domains and phosphorylation sites in the multifunctional pyrimidine-biosynthetic protein CAD. Eur. J. Biochem., 171, 583-588.
    • (1988) Eur. J. Biochem. , vol.171 , pp. 583-588
    • Carrey, E.A.1    Hardie, D.G.2
  • 12
    • 0022411522 scopus 로고
    • Increased carbamoyl-phosphate synthetase II concentration in rat hepatomas: Immunological evidence
    • Reardon,M.A. and Weber,G. (1985) Increased carbamoyl-phosphate synthetase II concentration in rat hepatomas: immunological evidence. Cancer Res., 45, 4412-4415.
    • (1985) Cancer Res. , vol.45 , pp. 4412-4415
    • Reardon, M.A.1    Weber, G.2
  • 13
    • 1542614599 scopus 로고    scopus 로고
    • Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells
    • Sigoillot,F.D., Sigoillot,S.M. and Guy,H.I. (2004) Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells. Int. J. Cancer, 109, 491-498.
    • (2004) Int. J. Cancer , vol.109 , pp. 491-498
    • Sigoillot, F.D.1    Sigoillot, S.M.2    Guy, H.I.3
  • 15
    • 0037013259 scopus 로고    scopus 로고
    • Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades
    • Sigoillot,F.D., Evans,D.R. and Guy,H.I. (2002) Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades. J. Biol. Chem., 277, 15745-15751.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15745-15751
    • Sigoillot, F.D.1    Evans, D.R.2    Guy, H.I.3
  • 17
    • 0037300817 scopus 로고    scopus 로고
    • De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways
    • Huang,M. and Graves,L.M. (2003) De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways. Cell. Mol. Life Sci., 60, 321-336.
    • (2003) Cell Mol. Life Sci. , vol.60 , pp. 321-336
    • Huang, M.1    Graves, L.M.2
  • 21
    • 0035834690 scopus 로고    scopus 로고
    • DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein
    • St Onge,R.P., Besley,B.D., Park,M., Casselman,R. and Davey,S. (2001) DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein. J. Biol. Chem., 276, 41898-41905.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41898-41905
    • St Onge, R.P.1    Besley, B.D.2    Park, M.3    Casselman, R.4    Davey, S.5
  • 22
    • 0037698170 scopus 로고    scopus 로고
    • A role for the phosphorylation of hRad9 in checkpoint signaling
    • St Onge,R.P., Besley,B.D., Pelley,J.L. and Davey,S. (2003) A role for the phosphorylation of hRad9 in checkpoint signaling. J. Biol. Chem., 278, 26620-26628.
    • (2003) J. Biol. Chem. , vol.278 , pp. 26620-26628
    • St Onge, R.P.1    Besley, B.D.2    Pelley, J.L.3    Davey, S.4
  • 23
    • 0027605113 scopus 로고
    • DNA damage and cell cycle regulation of ribonucleotide reductase
    • Elledge,S.J., Zhou,Z., Allen,J.B. and Navas,T.A. (1993) DNA damage and cell cycle regulation of ribonucleotide reductase. Bioessays, 15, 333-339.
    • (1993) Bioessays , vol.15 , pp. 333-339
    • Elledge, S.J.1    Zhou, Z.2    Allen, J.B.3    Navas, T.A.4
  • 24
    • 0037423223 scopus 로고    scopus 로고
    • Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase
    • Chabes,A., Georgieva,B., Domkin,V., Zhao,X., Rothstein,R. and Thelander,L. (2003) Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase. Cell, 112, 391-401.
    • (2003) Cell , vol.112 , pp. 391-401
    • Chabes, A.1    Georgieva, B.2    Domkin, V.3    Zhao, X.4    Rothstein, R.5    Thelander, L.6
  • 25
    • 0036072433 scopus 로고    scopus 로고
    • Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoa
    • Carrey,E.A., Dietz,C., Glubb,D.M., Loffler,M., Lucocq,J.M. and Watson,P.F. (2002) Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoa. Reproduction, 123, 757-768.
    • (2002) Reproduction , vol.123 , pp. 757-768
    • Carrey, E.A.1    Dietz, C.2    Glubb, D.M.3    Loffler, M.4    Lucocq, J.M.5    Watson, P.F.6
  • 26
    • 0031925587 scopus 로고    scopus 로고
    • Adenovirus preterminal protein binds to the CAD enzyme at active sites of viral DNA replication on the nuclear matrix
    • Angeletti,P.C. and Engler,J.A. (1998) Adenovirus preterminal protein binds to the CAD enzyme at active sites of viral DNA replication on the nuclear matrix. J. Virol., 72, 2896-2904.
    • (1998) J. Virol. , vol.72 , pp. 2896-2904
    • Angeletti, P.C.1    Engler, J.A.2
  • 27
    • 0035854804 scopus 로고    scopus 로고
    • Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex
    • Burtelow,M.A., Roos-Mattjus,P.M., Rauen,M., Babendure,J.R. and Karnitz,L.M. (2001) Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex. J. Biol. Chem., 276, 25903-25909.
    • (2001) J. Biol. Chem. , vol.276 , pp. 25903-25909
    • Burtelow, M.A.1    Roos-Mattjus, P.M.2    Rauen, M.3    Babendure, J.R.4    Karnitz, L.M.5
  • 28
    • 0034714240 scopus 로고    scopus 로고
    • Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage
    • Burtelow,M.A., Kaufmann,S.H. and Karnitz,L.M. (2000) Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage. J. Biol. Chem., 275, 26343-26348.
    • (2000) J. Biol. Chem. , vol.275 , pp. 26343-26348
    • Burtelow, M.A.1    Kaufmann, S.H.2    Karnitz, L.M.3
  • 29
    • 0142103820 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of Rad9 during apoptosis
    • Lee,M.W., Hirai,I. and Wang,H.G. (2003) Caspase-3-mediated cleavage of Rad9 during apoptosis. Oncogene, 22, 6340-6346.
    • (2003) Oncogene , vol.22 , pp. 6340-6346
    • Lee, M.W.1    Hirai, I.2    Wang, H.G.3
  • 30
    • 0017739096 scopus 로고
    • Purification from hamster cells of the multifunctional protein that initiates de novo synthesis of pyrimidine nucleotides
    • Coleman,P.F., Suttle,D.P. and Stark,G.R. (1977) Purification from hamster cells of the multifunctional protein that initiates de novo synthesis of pyrimidine nucleotides. J. Biol. Chem., 252, 6379-6385.
    • (1977) J. Biol. Chem. , vol.252 , pp. 6379-6385
    • Coleman, P.F.1    Suttle, D.P.2    Stark, G.R.3
  • 31
    • 0022435133 scopus 로고
    • Phosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesis
    • Carrey,E.A., Campbell,D.G. and Hardie,D.G. (1985) Phosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesis. EMBO J., 4, 3735-3742.
    • (1985) EMBO J. , vol.4 , pp. 3735-3742
    • Carrey, E.A.1    Campbell, D.G.2    Hardie, D.G.3
  • 32
    • 0034602704 scopus 로고    scopus 로고
    • Substitutions in the aspartate transcarbamoylase domain of hamster CAD disrupt oligomeric structure
    • Qiu,Y. and Davidson,J.N. (2000) Substitutions in the aspartate transcarbamoylase domain of hamster CAD disrupt oligomeric structure. Proc. Natl Acad. Sci. USA, 97, 97-102.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 97-102
    • Qiu, Y.1    Davidson, J.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.