p53 Modulates the Exonuclease Activity of Werner Syndrome Protein

Journal of Biological Chemistry

Volumn 276, Issue 37, 2001, Pages 35093-35102

  Brosh Jr , Robert M ^a   Karmakar, Parimal ^a   Sommers, Joshua A ^a   Yang, Qin ^b   Wang, Xin Wei ^b   Spillare, Elisa A ^b   Harris, Curtis C ^b   Bohr, Vilhelm A ^a,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; DNA; PROTEINS;

GENOMIC INSTABILITY;

BIOCHEMISTRY;

ENZYME; EXONUCLEASE; HELICASE; HYDROXYUREA; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN; ADENOSINE TRIPHOSPHATASE; EXODEOXYRIBONUCLEASE; RECQ HELICASE; WRN PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE S PHASE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; WERNER SYNDROME; CATALYSIS; CHEMISTRY; DNA DAMAGE; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATASES; APOPTOSIS; BASE SEQUENCE; CATALYSIS; DNA DAMAGE; DNA HELICASES; EXODEOXYRIBONUCLEASES; HUMANS; MOLECULAR SEQUENCE DATA; RECQ HELICASES; TUMOR SUPPRESSOR PROTEIN P53; WERNER SYNDROME;

EID: 0035860775     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103332200     Document Type: Article

References (50)

1. Lane, D. P. (1992) Nature 358, 15-16
2. Bennett, M. R. (1999) Biochem. Pharmacol. 58, 1089-1095
3. El-Deiry, W. S. (1998) Curr. Top. Microbiol. Immunol. 227, 121-137
4. Kastan, M. B., Zhan, Q., el-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., and Fornace, A. J. J. (1992) Cell 71, 587-597
5. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817-825
6. Levine, A. J. (1997) Cell 88, 323-331
7. Epstein, C. J., Martin, G. M., Schultz, A. L., and Motulsky, A. G. (1966) Medicine (Baltimore) 45, 177-221
8. Salk, D. (1982) Hum. Genet. 62, 1-5
9. Goto, M., Miller, R. W., Ishikawa, Y., and Sugano, H. (1996) Cancer Epidemiol. Biomark. Prev. 5, 239-246
10. Yu, C. E., Oshima, J., Fu, Y. H., Wijsman, E. M., Hisama, F., Alisch, R., Matthews, S., Nakura, J., Miki, T., Ouais, S., Martin, G. M., Mulligan, J., and Schellenberg, G. D. (1996) Science 272, 258-262
11. Gray, M. D., Shen, J. C., Kamath-Loeb, A. S., Blank, A., Sopher, B. L., Martin, G. M., Oshima, J., and Loeb, L. A. (1997) Nat. Genet. 17, 100-103
12. Shen, J. C., Gray, M. D., Oshima, J., and Loeb, L. A. (1998) Nucleic Acids Res. 26, 2879-2885
13. Brosh, R. M. J., Orren, D. K., Nehlin, J. O., Ravn, P. H., Kenny, M. K., Machwe, A., and Bohr, V. A. (1999) J. Biol. Chem. 274, 18341-18350
14. Huang, S., Li, B., Gray, M. D., Oshima, J., Mian, I. S., and Campisi, J. (1998) Nat. Genet. 20, 114-116
15. Kamath-Loeb, A. S., Shen, J. C., Loeb, L. A., and Fry, M. (1998) J. Biol. Chem. 273, 34145-34150
16. Shen, J. C., Gray, M. D., Oshima, J., Kamath-Loeb, A. S., Fry, M., and Loeb, L. A. (1998) J. Biol. Chem. 273, 34139-34144
17. Huang, S., Beresten, S., Li, B., Oshima, J., Ellis, N. A., and Campisi, J. (2000) Nucleic Acids Res. 28, 2396-2405
18. Spillare, E. A., Robles, A. I., Wang, X. W., Shen, J. C., Yu, C. E., Schellenberg, G. D., and Harris, C. C. (1999) Genes Dev. 13, 1355-1360
19. Blander, G., Kipnis, J., Leal, J. F., Yu, C. E., Schellenberg, G. D., and Oren, M. (1999) J. Biol. Chem. 274, 29463-29469
20. Yamabe, Y., Shimamoto, A., Goto, M., Yokota, J., Sugawara, M., and Furuichi, Y. (1998) Mol. Cell. Biol. 18, 6191-6200
21. Lombard, D. B., Beard, C., Johnson, B., Marciniak, R. A., Dausman, J., Bronson, R., Buhlmann, J. E., Lipman, R., Curry, R., Sharpe, A., Jaenisch, R., and Guarente, L. (1999) Mol. Cell. Biol. 20, 3286-3291
22. Orren, D. K., Brosh, R. M., Jr., Nehlin, J. O., Machwe, A., Gray, M. D., and Bohr, V. A. (1999) Nucleic Acids Res. 27, 3557-3566
23. Cooper, M. P., Machwe, A., Orren, D. K., Brosh, R. M., Ramsden, D., and Bohr, V. A. (2000) Genes Dev. 14, 907-912
24. Wang, X. W., Yeh, H., Schaeffer, L., Roy, R., Moncollin, V., Egly, J. M., Wang, Z., Freidberg, E. C., Evans, M. K., Taffe, B. G., Bohr, V. A., Weeda, G., Hoeijmakers, J. H. J., Forrester, K., and Harris, C. C. (1995) Nat. Genet. 10, 188-195
25. Matson, S. W., and Richardson, C. C. (1983) J. Biol. Chem. 258, 14009-14016
26. Brosh, R. M. J., Li, J. L., Kenny, M. K., Karow, J. K., Cooper, M. P., Kureekattil, R. P., Hickson, I. D., and Bohr, V. A. (2000) J. Biol. Chem. 275, 23500-23508
27. Bakalkin, G., Yakovleva, T., Selivanova, G., Magnusson, K. P., Szekely, L., Kiseleva, E., Klein, G., Terenius, L., and Wiman, K. G. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 413-417
28. Machwe, A., Ganunis, R., Bohr, V. A., and Orren, D. K. (2000) Nucleic Acids Res. 28, 2762-2770
29. Bargonetti, J., Manfredi, J. J., Chen, X., Marshak, D. R., and Prives, C. (1993) Genes Dev. 7, 2565-2574
30. Halazonetis, T. D., and Kandil, A. N. (1993) EMBO J. 12, 5057-5064
31. Pavletich, N. P., Chambers, K. A., and Pabo, C. O. (1993) Genes Dev. 7, 2556-2564
32. Wang, Y., Reed, M., Wang, P., Stenger, J. E., Mayr, G., Anderson, M. E., Schwedes, J. F., and Tegtmeyer, P. (1993) Genes Dev. 7, 2575-2586
33. Kern, S. E., Kinzler, K. W., Bruskin, A., Jarosz, D., Friedman, P., Prives, C., and Vogelstein, B. (1991) Science 252, 1708-1711
34. Orren, D. K., Machwe, A., Karmakar, P., Piotrowski, J., Cooper, M. P., and Bohr, V. A. (2001) Nucleic Acids Res. 29, 1926-1934
35. Kienzle, H., Baack, M., and Knippers, R. (1989) Eur. J. Biochem. 184, 181-186
36. Friedman, P. N., Kern, S. E., Vogelstein, B., and Prives, C. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9275-9279
37. Zhou, X., Wang, X. W., Xu, L., Hagiwara, K., Nagashima, M., Wolkowicz, R., Zurer, I., Rotter, V., and Harris, C. C. (1999) Cancer Res. 59, 843-848
38. Marciniak, R. A., Lombard, D. B., Johnson, F. B., and Guarente, L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6887-6892
39. Constantinou, A., Tarsounas, M., Karow, J. K., Brosh, R. M. J., Bohr, V. A., Hickson, I. D., and West, S. C. (2000) EMBO Reports 1, 80-84
40. Kern, S. E., Kinzler, K. W., Baker, S. J., Nigro, J. M., Rotter, V., Levine, A. J., Friedman, P., Prives, C., and Vogelstein, B. (1991) Oncogene 6, 131-136
41. Cox, L. S., Hupp, T., Midgley, C. A., and Lane, D. P. (1995) EMBO J. 14, 2099-2105
42. Lebel, M., Spillare, E. A., Harris, C. C., and Leder, P. (1999) J. Biol. Chem. 274, 37795-37799
43. Poot, M., Hoehn, H., Runger, T. M., and Martin, G. M. (1992) Exp. Cell Res. 202, 267-273
44. Takeuchi, F., Hanaoka, F., Goto, M., Akaoka, I., Hori, T., Yamada, M., and Miyamoto, T. (1982) Hum. Genet. 60, 365-368
45. Hanaoka, F., Yamada, M., Takeuchi, F., Goto, M., Miyamoto, T., and Hori, T. (1985) Adv. Exp. Med. Biol. 190, 439-457
46. Wagner, A. J., Kokontis, J. M., and Hay, N. (1994) Genes Dev. 8, 2817-2830
47. Caelles, C., Helmberg, A., and Karin, M. (1994) Nature 370, 220-223
48. Friedlander, P., Haupt, Y., Prives, C., and Oren, M. (1996) Mol. Cell. Biol. 16, 4961-4971
49. Wang, X. W., Vermeulen, W., Coursen, J. D., Gibson, M., Lupold, S. E., Forrester, K., Xu, G., Elmore, L., Yeh, H., Hoeijmakers, J. H., and Harris, C. C. (1996) Genes Dev. 10, 1219-1232
50. Robles, A. I., Wang, X. W., and Harris, C. C. (1999) Oncogene 18, 4681-4688.