Chemical-induced cancer incidence and underlying mechanisms in Fen1 mutant mice

Oncogene

Volumn 30, Issue 9, 2011, Pages 1072-1081

  Xu, H ^a,b   Zheng, L ^a   Dai, H ^a   Zhou, M ^a   Hua, Y ^a   Shen, B ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

aneuploidy; cancer; FEN1; long patch base excision repair; methylnitrosourea; tetraploidy

Indexed keywords

DNA BASE; FLAP ENDONUCLEASE 1; HYDROGEN PEROXIDE; METHYLNITROSOUREA; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CANCER INCIDENCE; CHEMICAL CARCINOGENESIS; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; DNA STRUCTURE; ENVIRONMENT; EXCISION REPAIR; FEMALE; GENE MUTATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MALE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PURIFICATION;

ADENOCARCINOMA; ANIMALS; CELL LINE; CHROMOSOME ABERRATIONS; DISEASE MODELS, ANIMAL; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPLICATION; FLAP ENDONUCLEASES; GENETIC PREDISPOSITION TO DISEASE; HYDROGEN PEROXIDE; LUNG NEOPLASMS; METHYLNITROSOUREA; MICE; MICE, MUTANT STRAINS; MICROSCOPY, FLUORESCENCE; POINT MUTATION;

MUS;

EID: 79952282182     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.482     Document Type: Article

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