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Volumn 155, Issue 1, 2013, Pages 1-35.e13

Corrigendum (Age-Related Macular Degeneration Revisited – Piecing the Puzzle: The LXIX Edward Jackson Memorial Lecture (2013) 155(1) (1–35.e13), (S0002939412007635) (10.1016/j.ajo.2012.10.018));Age-related macular degeneration revisited - Piecing the puzzle: The LXIX edward jackson memorial lecture

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; COMPLEMENT; INFLAMMASOME; LIPOFUSCIN;

EID: 84871180605     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2018.09.023     Document Type: Erratum
Times cited : (219)

References (455)
  • 1
    • 15044365896 scopus 로고    scopus 로고
    • The significance of the Edward Jackson lecture
    • T.J. Liesegang, H.D. Hoskins, and A.D. Jensen The significance of the Edward Jackson lecture Am J Ophthalmol 139 3 2005 530 532
    • (2005) Am J Ophthalmol , vol.139 , Issue.3 , pp. 530-532
    • Liesegang, T.J.1    Hoskins, H.D.2    Jensen, A.D.3
  • 2
    • 84860257625 scopus 로고    scopus 로고
    • World Health Organization Accessed October 1
    • World Health Organization. Priority Eye Diseases. Available at http://www.who.int/blindness/causes/priority. Accessed October 1, 2012.
    • (2012) Priority Eye Diseases
  • 3
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • P.J. Rosenfeld, D.M. Brown, and J.S. Heier Ranibizumab for neovascular age-related macular degeneration N Engl J Med 355 14 2006 1419 1431
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 4
    • 79956218863 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for neovascular age-related macular degeneration
    • CATT Research Group
    • CATT Research Group D.F. Martin, and M.G. Maguire Ranibizumab and bevacizumab for neovascular age-related macular degeneration N Engl J Med 364 20 2011 1897 1908
    • (2011) N Engl J Med , vol.364 , Issue.20 , pp. 1897-1908
    • Martin, D.F.1    Maguire, M.G.2
  • 5
    • 84863320414 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: Two-year results
    • D.F. Martin, M.G. Maguire, and S.L. Fine Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results Ophthalmology 119 7 2012 1388 1398
    • (2012) Ophthalmology , vol.119 , Issue.7 , pp. 1388-1398
    • Martin, D.F.1    Maguire, M.G.2    Fine, S.L.3
  • 6
    • 45149098715 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • R.D. Jager, W.F. Mieler, and J.W. Miller Age-related macular degeneration N Engl J Med 358 24 2008 2606 2617
    • (2008) N Engl J Med , vol.358 , Issue.24 , pp. 2606-2617
    • Jager, R.D.1    Mieler, W.F.2    Miller, J.W.3
  • 7
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • P.T. de Jong Age-related macular degeneration N Engl J Med 355 14 2006 1474 1485
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1474-1485
    • De Jong, P.T.1
  • 8
    • 27744508407 scopus 로고    scopus 로고
    • The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS report no. 17
    • M.D. Davis, R.E. Gangnon, and L.Y. Lee The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS report no. 17 Arch Ophthalmol 123 11 2005 1484 1498
    • (2005) Arch Ophthalmol , vol.123 , Issue.11 , pp. 1484-1498
    • Davis, M.D.1    Gangnon, R.E.2    Lee, L.Y.3
  • 9
    • 27744516278 scopus 로고    scopus 로고
    • A simplified severity scale for age-related macular degeneration: AREDS report no. 18
    • F.L. Ferris, M.D. Davis, and T.E. Clemons A simplified severity scale for age-related macular degeneration: AREDS report no. 18 Arch Ophthalmol 123 11 2005 1570 1574
    • (2005) Arch Ophthalmol , vol.123 , Issue.11 , pp. 1570-1574
    • Ferris, F.L.1    Davis, M.D.2    Clemons, T.E.3
  • 10
    • 0024410801 scopus 로고
    • The grading and prevalence of macular degeneration in Chesapeake Bay watermen
    • N.M. Bressler, S.B. Bressler, S.K. West, S.L. Fine, and H.R. Taylor The grading and prevalence of macular degeneration in Chesapeake Bay watermen Arch Ophthalmol 107 6 1989 847 852
    • (1989) Arch Ophthalmol , vol.107 , Issue.6 , pp. 847-852
    • Bressler, N.M.1    Bressler, S.B.2    West, S.K.3    Fine, S.L.4    Taylor, H.R.5
  • 11
    • 33847721424 scopus 로고    scopus 로고
    • Heredity of small hard drusen in twins aged 20-46 years
    • I.C. Munch, B. Sander, and L. Kessel Heredity of small hard drusen in twins aged 20-46 years Invest Ophthalmol Vis Sci 48 2 2007 833 838
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , Issue.2 , pp. 833-838
    • Munch, I.C.1    Sander, B.2    Kessel, L.3
  • 13
    • 77952891296 scopus 로고    scopus 로고
    • Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age-related macular degeneration
    • S. Schmitz-Valckenberg, J.S. Steinberg, M. Fleckenstein, S. Visvalingam, C.K. Brinkmann, and F.G. Holz Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age-related macular degeneration Ophthalmology 117 6 2010 1169 1176
    • (2010) Ophthalmology , vol.117 , Issue.6 , pp. 1169-1176
    • Schmitz-Valckenberg, S.1    Steinberg, J.S.2    Fleckenstein, M.3    Visvalingam, S.4    Brinkmann, C.K.5    Holz, F.G.6
  • 14
    • 83455212184 scopus 로고    scopus 로고
    • Risk assessment model for development of advanced age-related macular degeneration
    • M.L. Klein, P.J. Francis, F.L. Ferris 3rd, S.C. Hamon, and T.E. Clemons Risk assessment model for development of advanced age-related macular degeneration Arch Ophthalmol 129 12 2011 1543 1550
    • (2011) Arch Ophthalmol , vol.129 , Issue.12 , pp. 1543-1550
    • Klein, M.L.1    Francis, P.J.2    Ferris III, F.L.3    Hamon, S.C.4    Clemons, T.E.5
  • 16
    • 34548293286 scopus 로고    scopus 로고
    • Cone- and rod-mediated dark adaptation impairment in age-related maculopathy
    • C. Owsley, G. McGwin Jr., G.R. Jackson, K. Kallies, and M. Clark Cone- and rod-mediated dark adaptation impairment in age-related maculopathy Ophthalmology 114 9 2007 1728 1735
    • (2007) Ophthalmology , vol.114 , Issue.9 , pp. 1728-1735
    • Owsley, C.1    Mcgwin Jr., G.2    Jackson, G.R.3    Kallies, K.4    Clark, M.5
  • 17
    • 78649940351 scopus 로고    scopus 로고
    • A short-duration dark adaptation protocol for assessment of age-related maculopathy
    • G.R. Jackson, and J.G. Edwards A short-duration dark adaptation protocol for assessment of age-related maculopathy J Ocul Biol Dis Infor 1 1 2008 7 11
    • (2008) J Ocul Biol Dis Infor , vol.1 , Issue.1 , pp. 7-11
    • Jackson, G.R.1    Edwards, J.G.2
  • 18
    • 0032786405 scopus 로고    scopus 로고
    • Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with age-related macular degeneration and histologic examination of surgically excised choroidal neovascular membranes
    • C.W. Spraul, G.E. Lang, H.E. Grossniklaus, and G.K. Lang Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with age-related macular degeneration and histologic examination of surgically excised choroidal neovascular membranes Surv Ophthalmol 44 Suppl 1 1999 S10 S32
    • (1999) Surv Ophthalmol , vol.44 , Issue.SUPPL. 1
    • Spraul, C.W.1    Lang, G.E.2    Grossniklaus, H.E.3    Lang, G.K.4
  • 19
    • 0344791691 scopus 로고    scopus 로고
    • Basal linear deposit and large drusen are specific for early age-related maculopathy
    • C.A. Curcio, and C.L. Millican Basal linear deposit and large drusen are specific for early age-related maculopathy Arch Ophthalmol 117 3 1999 329 339
    • (1999) Arch Ophthalmol , vol.117 , Issue.3 , pp. 329-339
    • Curcio, C.A.1    Millican, C.L.2
  • 20
    • 0842310831 scopus 로고    scopus 로고
    • Elastic fiber homeostasis requires lysyl oxidase-like 1 protein
    • X. Liu, Y. Zhao, and J. Gao Elastic fiber homeostasis requires lysyl oxidase-like 1 protein Nat Genet 36 2 2004 178 182
    • (2004) Nat Genet , vol.36 , Issue.2 , pp. 178-182
    • Liu, X.1    Zhao, Y.2    Gao, J.3
  • 21
    • 11144230943 scopus 로고    scopus 로고
    • Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration
    • N.H. Chong, J. Keonin, and P.J. Luthert Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration Am J Pathol 166 1 2005 241 251
    • (2005) Am J Pathol , vol.166 , Issue.1 , pp. 241-251
    • Chong, N.H.1    Keonin, J.2    Luthert, P.J.3
  • 22
    • 0031013169 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye
    • R.N. Fariss, S.S. Apte, B.R. Olsen, K. Iwata, and A.H. Milam Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye Am J Pathol 150 1 1997 323 328
    • (1997) Am J Pathol , vol.150 , Issue.1 , pp. 323-328
    • Fariss, R.N.1    Apte, S.S.2    Olsen, B.R.3    Iwata, K.4    Milam, A.H.5
  • 23
    • 0032820720 scopus 로고    scopus 로고
    • TIMP-3 in Bruch's membrane: Changes during aging and in age-related macular degeneration
    • M. Kamei, and J.G. Hollyfield TIMP-3 in Bruch's membrane: changes during aging and in age-related macular degeneration Invest Ophthalmol Vis Sci 40 10 1999 2367 2375
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.10 , pp. 2367-2375
    • Kamei, M.1    Hollyfield, J.G.2
  • 24
    • 21344436154 scopus 로고    scopus 로고
    • Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age related macular degeneration
    • A. Bindewald, S. Schmitz-Valckenberg, and J.J. Jorzik Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age related macular degeneration Br J Ophthalmol 89 7 2005 874 878
    • (2005) Br J Ophthalmol , vol.89 , Issue.7 , pp. 874-878
    • Bindewald, A.1    Schmitz-Valckenberg, S.2    Jorzik, J.J.3
  • 25
    • 33745641375 scopus 로고    scopus 로고
    • Correlation between the area of increased autofluorescence surrounding geographic atrophy and disease progression in patients with AMD
    • S. Schmitz-Valckenberg, A. Bindewald-Wittich, and J. Dolar-Szczasny Correlation between the area of increased autofluorescence surrounding geographic atrophy and disease progression in patients with AMD Invest Ophthalmol Vis Sci 47 6 2006 2648 2654
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.6 , pp. 2648-2654
    • Schmitz-Valckenberg, S.1    Bindewald-Wittich, A.2    Dolar-Szczasny, J.3
  • 26
    • 0026545904 scopus 로고
    • Classification of retinal pigment epithelial detachments associated with drusen
    • M.E. Hartnett, J.J. Weiter, A. Garsd, and A.E. Jalkh Classification of retinal pigment epithelial detachments associated with drusen Graefes Arch Clin Exp Ophthalmol 230 1 1992 11 19
    • (1992) Graefes Arch Clin Exp Ophthalmol , vol.230 , Issue.1 , pp. 11-19
    • Hartnett, M.E.1    Weiter, J.J.2    Garsd, A.3    Jalkh, A.E.4
  • 27
    • 58149232750 scopus 로고    scopus 로고
    • Clinicopathologic correlation of retinal angiomatous proliferation
    • D.M. Monson, J.R. Smith, M.L. Klein, and D.J. Wilson Clinicopathologic correlation of retinal angiomatous proliferation Arch Ophthalmol 126 12 2008 1664 1668
    • (2008) Arch Ophthalmol , vol.126 , Issue.12 , pp. 1664-1668
    • Monson, D.M.1    Smith, J.R.2    Klein, M.L.3    Wilson, D.J.4
  • 28
    • 40449090521 scopus 로고    scopus 로고
    • Type 3 neovascularization: The expanded spectrum of retinal angiomatous proliferation
    • K.B. Freund, I.V. Ho, and I.A. Barbazetto Type 3 neovascularization: the expanded spectrum of retinal angiomatous proliferation Retina 28 2 2008 201 211
    • (2008) Retina , vol.28 , Issue.2 , pp. 201-211
    • Freund, K.B.1    Ho, I.V.2    Barbazetto, I.A.3
  • 29
    • 0032741873 scopus 로고    scopus 로고
    • Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration
    • L.A. Yannuzzi, D.W. Wong, and B.S. Sforzolini Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration Arch Ophthalmol 117 11 1999 1503 1510
    • (1999) Arch Ophthalmol , vol.117 , Issue.11 , pp. 1503-1510
    • Yannuzzi, L.A.1    Wong, D.W.2    Sforzolini, B.S.3
  • 30
    • 77951622411 scopus 로고    scopus 로고
    • The prevalence of age-related macular degeneration in Asians: A systematic review and meta-analysis
    • R. Kawasaki, M. Yasuda, and S.J. Song The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis Ophthalmology 117 5 2010 921 927
    • (2010) Ophthalmology , vol.117 , Issue.5 , pp. 921-927
    • Kawasaki, R.1    Yasuda, M.2    Song, S.J.3
  • 31
    • 33646877287 scopus 로고    scopus 로고
    • Visual function and dysfunction in early and late age-related maculopathy
    • R.E. Hogg, and U. Chakravarthy Visual function and dysfunction in early and late age-related maculopathy Prog Retin Eye Res 25 3 2006 249 276
    • (2006) Prog Retin Eye Res , vol.25 , Issue.3 , pp. 249-276
    • Hogg, R.E.1    Chakravarthy, U.2
  • 32
    • 0015445712 scopus 로고
    • Drusen and disciform macular detachment and degeneration
    • J.D. Gass Drusen and disciform macular detachment and degeneration Trans Am Ophthalmol Soc 70 1972 409 436
    • (1972) Trans Am Ophthalmol Soc , vol.70 , pp. 409-436
    • Gass, J.D.1
  • 33
    • 0017704582 scopus 로고
    • The framingham eye study. I. Outline and major prevalence findings
    • H.A. Kahn, H.M. Leibowitz, and J.P. Ganley The Framingham Eye Study. I. Outline and major prevalence findings Am J Epidemiol 106 1 1977 17 32
    • (1977) Am J Epidemiol , vol.106 , Issue.1 , pp. 17-32
    • Kahn, H.A.1    Leibowitz, H.M.2    Ganley, J.P.3
  • 34
    • 0023813198 scopus 로고
    • Factors associated with age-related macular degeneration. An analysis of data from the first National Health and Nutrition Examination Survey
    • J. Goldberg, G. Flowerdew, E. Smith, J.A. Brody, and M.O. Tso Factors associated with age-related macular degeneration. An analysis of data from the first National Health and Nutrition Examination Survey Am J Epidemiol 128 4 1988 700 710
    • (1988) Am J Epidemiol , vol.128 , Issue.4 , pp. 700-710
    • Goldberg, J.1    Flowerdew, G.2    Smith, E.3    Brody, J.A.4    Tso, M.O.5
  • 35
    • 0026439413 scopus 로고
    • Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group Arch Ophthalmol 110 12 1992 1701 1708
    • (1992) Arch Ophthalmol , vol.110 , Issue.12 , pp. 1701-1708
  • 36
    • 78649936436 scopus 로고    scopus 로고
    • Clinical risk factors for age-related macular degeneration: A systematic review and meta-analysis
    • U. Chakravarthy, T.Y. Wong, and A. Fletcher Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis BMC Ophthalmol 10 2010 31
    • (2010) BMC Ophthalmol , vol.10 , pp. 31
    • Chakravarthy, U.1    Wong, T.Y.2    Fletcher, A.3
  • 37
    • 0024359696 scopus 로고
    • Exposure to sunlight and other risk factors for age-related macular degeneration
    • S.K. West, F.S. Rosenthal, and N.M. Bressler Exposure to sunlight and other risk factors for age-related macular degeneration Arch Ophthalmol 107 6 1989 875 879
    • (1989) Arch Ophthalmol , vol.107 , Issue.6 , pp. 875-879
    • West, S.K.1    Rosenthal, F.S.2    Bressler, N.M.3
  • 40
    • 0033652453 scopus 로고    scopus 로고
    • Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study report number 3
    • Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study report number 3 Ophthalmology 107 12 2000 2224 2232
    • (2000) Ophthalmology , vol.107 , Issue.12 , pp. 2224-2232
  • 41
    • 0042362122 scopus 로고    scopus 로고
    • Relationship between refraction and prevalent as well as incident age-related maculopathy: The Rotterdam Study
    • M.K. Ikram, R. van Leeuwen, J.R. Vingerling, A. Hofman, and P.T. de Jong Relationship between refraction and prevalent as well as incident age-related maculopathy: the Rotterdam Study Invest Ophthalmol Vis Sci 44 9 2003 3778 3782
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.9 , pp. 3778-3782
    • Ikram, M.K.1    Van Leeuwen, R.2    Vingerling, J.R.3    Hofman, A.4    De Jong, P.T.5
  • 42
    • 33748459406 scopus 로고    scopus 로고
    • Associated factors for age related maculopathy in the adult population in China: The Beijing Eye Study
    • L. Xu, Y. Li, Y. Zheng, and J.B. Jonas Associated factors for age related maculopathy in the adult population in China: the Beijing Eye Study Br J Ophthalmol 90 9 2006 1087 1090
    • (2006) Br J Ophthalmol , vol.90 , Issue.9 , pp. 1087-1090
    • Xu, L.1    Li, Y.2    Zheng, Y.3    Jonas, J.B.4
  • 43
    • 0027546561 scopus 로고
    • Refractive error and choroidal perfusion characteristics in patients with choroidal neovascularization and age-related macular degeneration
    • T. Boker, T. Fang, and R. Steinmetz Refractive error and choroidal perfusion characteristics in patients with choroidal neovascularization and age-related macular degeneration Ger J Ophthalmol 2 1 1993 10 13
    • (1993) Ger J Ophthalmol , vol.2 , Issue.1 , pp. 10-13
    • Boker, T.1    Fang, T.2    Steinmetz, R.3
  • 44
    • 0027397668 scopus 로고
    • Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group Arch Ophthalmol 111 1 1993 104 109
    • (1993) Arch Ophthalmol , vol.111 , Issue.1 , pp. 104-109
  • 45
    • 0027946498 scopus 로고
    • Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group
    • J.M. Seddon, U.A. Ajani, and R.D. Sperduto Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group JAMA 272 18 1994 1413 1420
    • (1994) JAMA , vol.272 , Issue.18 , pp. 1413-1420
    • Seddon, J.M.1    Ajani, U.A.2    Sperduto, R.D.3
  • 46
    • 0017654306 scopus 로고
    • The Framingham Eye Study. II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study
    • H.A. Kahn, H.M. Leibowitz, and J.P. Ganley The Framingham Eye Study. II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study Am J Epidemiol 106 1 1977 33 41
    • (1977) Am J Epidemiol , vol.106 , Issue.1 , pp. 33-41
    • Kahn, H.A.1    Leibowitz, H.M.2    Ganley, J.P.3
  • 47
    • 0025038027 scopus 로고
    • Aging changes in Bruch's membrane. A histochemical and morphologic study
    • D. Pauleikhoff, C.A. Harper, J. Marshall, and A.C. Bird Aging changes in Bruch's membrane. A histochemical and morphologic study Ophthalmology 97 2 1990 171 178
    • (1990) Ophthalmology , vol.97 , Issue.2 , pp. 171-178
    • Pauleikhoff, D.1    Harper, C.A.2    Marshall, J.3    Bird, A.C.4
  • 48
  • 49
    • 0029950660 scopus 로고    scopus 로고
    • Hydrodynamics of ageing Bruch's membrane: Implications for macular disease
    • C. Starita, A.A. Hussain, S. Pagliarini, and J. Marshall Hydrodynamics of ageing Bruch's membrane: implications for macular disease Exp Eye Res 62 5 1996 565 572
    • (1996) Exp Eye Res , vol.62 , Issue.5 , pp. 565-572
    • Starita, C.1    Hussain, A.A.2    Pagliarini, S.3    Marshall, J.4
  • 51
    • 37349021003 scopus 로고    scopus 로고
    • Subendothelial lipoprotein retention as the initiating process in atherosclerosis: Update and therapeutic implications
    • I. Tabas, K.J. Williams, and J. Boren Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications Circulation 116 16 2007 1832 1844
    • (2007) Circulation , vol.116 , Issue.16 , pp. 1832-1844
    • Tabas, I.1    Williams, K.J.2    Boren, J.3
  • 54
    • 0034956476 scopus 로고    scopus 로고
    • Photoreceptor topography in ageing and age-related maculopathy
    • C.A. Curcio Photoreceptor topography in ageing and age-related maculopathy Eye (Lond) 15 Pt 3 2001 376 383
    • (2001) Eye (Lond) , vol.15 , Issue.PART 3 , pp. 376-383
    • Curcio, C.A.1
  • 55
    • 0014263170 scopus 로고
    • The retinal pigment epithelium. II. Histologic changes associated with age
    • E. Friedman, and M.O. Ts'o The retinal pigment epithelium. II. Histologic changes associated with age Arch Ophthalmol 79 3 1968 315 320
    • (1968) Arch Ophthalmol , vol.79 , Issue.3 , pp. 315-320
    • Friedman, E.1    Ts'O, M.O.2
  • 56
    • 0031278861 scopus 로고    scopus 로고
    • A hemodynamic model of the pathogenesis of age-related macular degeneration
    • E. Friedman A hemodynamic model of the pathogenesis of age-related macular degeneration Am J Ophthalmol 124 5 1997 677 682
    • (1997) Am J Ophthalmol , vol.124 , Issue.5 , pp. 677-682
    • Friedman, E.1
  • 57
    • 0001063063 scopus 로고
    • Contribution to the theory and practice of tonometry
    • J.S. Friedenwald Contribution to the theory and practice of tonometry Am J Ophthalmol 20 1937 985 1024
    • (1937) Am J Ophthalmol , vol.20 , pp. 985-1024
    • Friedenwald, J.S.1
  • 58
    • 0005668514 scopus 로고
    • The pathogenesis of disciform degeneration of the macula
    • F.H. Verhoeff, and H.P. Grossman The pathogenesis of disciform degeneration of the macula Trans Am Ophthalmol Soc 35 1937 262 294
    • (1937) Trans Am Ophthalmol Soc , vol.35 , pp. 262-294
    • Verhoeff, F.H.1    Grossman, H.P.2
  • 59
    • 0030471907 scopus 로고    scopus 로고
    • Morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in eyes with age-related macular degeneration
    • C.W. Spraul, G.E. Lang, and H.E. Grossniklaus Morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in eyes with age-related macular degeneration Invest Ophthalmol Vis Sci 37 13 1996 2724 2735
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , Issue.13 , pp. 2724-2735
    • Spraul, C.W.1    Lang, G.E.2    Grossniklaus, H.E.3
  • 60
    • 49749092092 scopus 로고    scopus 로고
    • The pathogenesis of age-related macular degeneration
    • E. Friedman The pathogenesis of age-related macular degeneration Am J Ophthalmol 146 3 2008 348 349
    • (2008) Am J Ophthalmol , vol.146 , Issue.3 , pp. 348-349
    • Friedman, E.1
  • 61
    • 0015258943 scopus 로고
    • Role of the retinal pigment epithelium in macular disease
    • M.J. Hogan Role of the retinal pigment epithelium in macular disease Trans Am Acad Ophthalmol Otolaryngol 76 1 1972 64 80
    • (1972) Trans Am Acad Ophthalmol Otolaryngol , vol.76 , Issue.1 , pp. 64-80
    • Hogan, M.J.1
  • 62
    • 0017897377 scopus 로고
    • The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium
    • G.L. Wing, G.C. Blanchard, and J.J. Weiter The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium Invest Ophthalmol Vis Sci 17 7 1978 601 607
    • (1978) Invest Ophthalmol Vis Sci , vol.17 , Issue.7 , pp. 601-607
    • Wing, G.L.1    Blanchard, G.C.2    Weiter, J.J.3
  • 63
    • 58449086657 scopus 로고    scopus 로고
    • Fundus autofluorescence and progression of age-related macular degeneration
    • S. Schmitz-Valckenberg, M. Fleckenstein, H.P. Scholl, and F.G. Holz Fundus autofluorescence and progression of age-related macular degeneration Surv Ophthalmol 54 1 2009 96 117
    • (2009) Surv Ophthalmol , vol.54 , Issue.1 , pp. 96-117
    • Schmitz-Valckenberg, S.1    Fleckenstein, M.2    Scholl, H.P.3    Holz, F.G.4
  • 65
    • 0033017053 scopus 로고    scopus 로고
    • Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin
    • F.G. Holz, F. Schutt, and J. Kopitz Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin Invest Ophthalmol Vis Sci 40 3 1999 737 743
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.3 , pp. 737-743
    • Holz, F.G.1    Schutt, F.2    Kopitz, J.3
  • 66
    • 0037133673 scopus 로고    scopus 로고
    • The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium
    • S.C. Finnemann, L.W. Leung, and E. Rodriguez-Boulan The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium Proc Natl Acad Sci U S A 99 6 2002 3842 3847
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.6 , pp. 3842-3847
    • Finnemann, S.C.1    Leung, L.W.2    Rodriguez-Boulan, E.3
  • 67
    • 34547466583 scopus 로고    scopus 로고
    • The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells
    • A. Lakkaraju, S.C. Finnemann, and E. Rodriguez-Boulan The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells Proc Natl Acad Sci U S A 104 26 2007 11026 11031
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.26 , pp. 11026-11031
    • Lakkaraju, A.1    Finnemann, S.C.2    Rodriguez-Boulan, E.3
  • 68
    • 0035040640 scopus 로고    scopus 로고
    • Blue light-induced apoptosis of A2E-containing RPE: Involvement of caspase-3 and protection by Bcl-2
    • J.R. Sparrow, and B. Cai Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2 Invest Ophthalmol Vis Sci 42 6 2001 1356 1362
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.6 , pp. 1356-1362
    • Sparrow, J.R.1    Cai, B.2
  • 69
    • 62649135260 scopus 로고    scopus 로고
    • Complement activation by bisretinoid constituents of RPE lipofuscin
    • J. Zhou, S.R. Kim, B.S. Westlund, and J.R. Sparrow Complement activation by bisretinoid constituents of RPE lipofuscin Invest Ophthalmol Vis Sci 50 3 2009 1392 1399
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.3 , pp. 1392-1399
    • Zhou, J.1    Kim, S.R.2    Westlund, B.S.3    Sparrow, J.R.4
  • 70
    • 18044366931 scopus 로고    scopus 로고
    • RPE lipofuscin and its role in retinal pathobiology
    • J.R. Sparrow, and M. Boulton RPE lipofuscin and its role in retinal pathobiology Exp Eye Res 80 5 2005 595 606
    • (2005) Exp Eye Res , vol.80 , Issue.5 , pp. 595-606
    • Sparrow, J.R.1    Boulton, M.2
  • 71
    • 77951254301 scopus 로고    scopus 로고
    • Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD)
    • H.L. Ramkumar, J. Zhang, and C.C. Chan Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD) Prog Retin Eye Res 29 3 2010 169 190
    • (2010) Prog Retin Eye Res , vol.29 , Issue.3 , pp. 169-190
    • Ramkumar, H.L.1    Zhang, J.2    Chan, C.C.3
  • 72
    • 77956402099 scopus 로고    scopus 로고
    • Abundant lipid and protein components of drusen
    • L. Wang, M.E. Clark, and D.K. Crossman Abundant lipid and protein components of drusen PLoS One 5 4 2010 e10329
    • (2010) PLoS One , vol.5 , Issue.4 , pp. 10329
    • Wang, L.1    Clark, M.E.2    Crossman, D.K.3
  • 73
    • 81255168210 scopus 로고    scopus 로고
    • Evidence of association of APOE with age-related macular degeneration: A pooled analysis of 15 studies
    • G.J. McKay, C.C. Patterson, and U. Chakravarthy Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies Hum Mutat 32 12 2011 1407 1416
    • (2011) Hum Mutat , vol.32 , Issue.12 , pp. 1407-1416
    • McKay, G.J.1    Patterson, C.C.2    Chakravarthy, U.3
  • 74
    • 0037015020 scopus 로고    scopus 로고
    • The Alzheimer's A beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
    • L.V. Johnson, W.P. Leitner, A.J. Rivest, M.K. Staples, M.J. Radeke, and D.H. Anderson The Alzheimer's A beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration Proc Natl Acad Sci U S A 99 18 2002 11830 11835
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.18 , pp. 11830-11835
    • Johnson, L.V.1    Leitner, W.P.2    Rivest, A.J.3    Staples, M.K.4    Radeke, M.J.5    Anderson, D.H.6
  • 75
    • 0037975774 scopus 로고    scopus 로고
    • Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas
    • T. Dentchev, A.H. Milam, V.M. Lee, J.Q. Trojanowski, and J.L. Dunaief Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas Mol Vis 9 2003 184 190
    • (2003) Mol Vis , vol.9 , pp. 184-190
    • Dentchev, T.1    Milam, A.H.2    Lee, V.M.3    Trojanowski, J.Q.4    Dunaief, J.L.5
  • 76
    • 0345760069 scopus 로고    scopus 로고
    • Characterization of beta amyloid assemblies in drusen: The deposits associated with aging and age-related macular degeneration
    • D.H. Anderson, K.C. Talaga, A.J. Rivest, E. Barron, G.S. Hageman, and L.V. Johnson Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration Exp Eye Res 78 2 2004 243 256
    • (2004) Exp Eye Res , vol.78 , Issue.2 , pp. 243-256
    • Anderson, D.H.1    Talaga, K.C.2    Rivest, A.J.3    Barron, E.4    Hageman, G.S.5    Johnson, L.V.6
  • 77
    • 77950521126 scopus 로고    scopus 로고
    • Cystatin C in macular and neuronal degenerations: Implications for mechanism(s) of age-related macular degeneration
    • L. Paraoan, P. Hiscott, C. Gosden, and I. Grierson Cystatin C in macular and neuronal degenerations: implications for mechanism(s) of age-related macular degeneration Vision Res 50 7 2010 737 742
    • (2010) Vision Res , vol.50 , Issue.7 , pp. 737-742
    • Paraoan, L.1    Hiscott, P.2    Gosden, C.3    Grierson, I.4
  • 78
    • 79961005068 scopus 로고    scopus 로고
    • Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
    • J.D. Ding, L.V. Johnson, and R. Herrmann Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration Proc Natl Acad Sci U S A 108 28 2011 E279 E287
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.28
    • Ding, J.D.1    Johnson, L.V.2    Herrmann, R.3
  • 79
    • 26444478610 scopus 로고    scopus 로고
    • The potential role of amyloid beta in the pathogenesis of age-related macular degeneration
    • T. Yoshida, K. Ohno-Matsui, and S. Ichinose The potential role of amyloid beta in the pathogenesis of age-related macular degeneration J Clin Invest 115 10 2005 2793 2800
    • (2005) J Clin Invest , vol.115 , Issue.10 , pp. 2793-2800
    • Yoshida, T.1    Ohno-Matsui, K.2    Ichinose, S.3
  • 80
    • 78049299159 scopus 로고    scopus 로고
    • Viewing ageing eyes: Diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages
    • J. Hoh Kam, E. Lenassi, and G. Jeffery Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages PLoS One 5 2010 10
    • (2010) PLoS One , Issue.5 , pp. 10
    • Hoh Kam, J.1    Lenassi, E.2    Jeffery, G.3
  • 81
    • 34248152673 scopus 로고    scopus 로고
    • The role of inflammation and infection in age-related macular degeneration
    • F.C. Barouch, and J.W. Miller The role of inflammation and infection in age-related macular degeneration Int Ophthalmol Clin 47 2 2007 185 197
    • (2007) Int Ophthalmol Clin , vol.47 , Issue.2 , pp. 185-197
    • Barouch, F.C.1    Miller, J.W.2
  • 82
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • G.S. Hageman, P.J. Luthert, N.H. Victor Chong, L.V. Johnson, D.H. Anderson, and R.F. Mullins An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration Prog Retin Eye Res 20 6 2001 705 732
    • (2001) Prog Retin Eye Res , vol.20 , Issue.6 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor Chong, N.H.3    Johnson, L.V.4    Anderson, D.H.5    Mullins, R.F.6
  • 83
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • D.H. Anderson, R.F. Mullins, G.S. Hageman, and L.V. Johnson A role for local inflammation in the formation of drusen in the aging eye Am J Ophthalmol 134 3 2002 411 431
    • (2002) Am J Ophthalmol , vol.134 , Issue.3 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 84
    • 0022590076 scopus 로고
    • Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium
    • P.L. Penfold, M.C. Killingsworth, and S.H. Sarks Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium Invest Ophthalmol Vis Sci 27 3 1986 364 371
    • (1986) Invest Ophthalmol Vis Sci , vol.27 , Issue.3 , pp. 364-371
    • Penfold, P.L.1    Killingsworth, M.C.2    Sarks, S.H.3
  • 86
    • 0030931699 scopus 로고    scopus 로고
    • Modulation of major histocompatibility complex class II expression in retinas with age-related macular degeneration
    • P.L. Penfold, S.C. Liew, M.C. Madigan, and J.M. Provis Modulation of major histocompatibility complex class II expression in retinas with age-related macular degeneration Invest Ophthalmol Vis Sci 38 10 1997 2125 2133
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , Issue.10 , pp. 2125-2133
    • Penfold, P.L.1    Liew, S.C.2    Madigan, M.C.3    Provis, J.M.4
  • 87
    • 84870515243 scopus 로고    scopus 로고
    • A2E accumulation influences retinal microglial activation and complement regulation
    • doi:10.1016/j.neurobiolaging.2012.06.010
    • Ma W, Coon S, Zhao L, Fariss RN, Wong WT. A2E accumulation influences retinal microglial activation and complement regulation. Neurobiol Aging. doi:10.1016/j.neurobiolaging.2012.06.010.
    • Neurobiol Aging
    • Ma, W.1    Coon, S.2    Zhao, L.3    Fariss, R.N.4    Wong, W.T.5
  • 89
    • 0025736918 scopus 로고
    • Antiretinal antibodies in serum of patients with age-related macular degeneration
    • D.H. Gurne, M.O. Tso, D.P. Edward, and H. Ripps Antiretinal antibodies in serum of patients with age-related macular degeneration Ophthalmology 98 5 1991 602 607
    • (1991) Ophthalmology , vol.98 , Issue.5 , pp. 602-607
    • Gurne, D.H.1    Tso, M.O.2    Edward, D.P.3    Ripps, H.4
  • 90
    • 21244450029 scopus 로고    scopus 로고
    • Circulating anti-retinal antibodies as immune markers in age-related macular degeneration
    • N. Patel, M. Ohbayashi, and A.K. Nugent Circulating anti-retinal antibodies as immune markers in age-related macular degeneration Immunology 115 3 2005 422 430
    • (2005) Immunology , vol.115 , Issue.3 , pp. 422-430
    • Patel, N.1    Ohbayashi, M.2    Nugent, A.K.3
  • 91
    • 0023199438 scopus 로고
    • Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body
    • D.A. Newsome, A.T. Hewitt, W. Huh, P.G. Robey, and J.R. Hassell Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body Am J Ophthalmol 104 4 1987 373 381
    • (1987) Am J Ophthalmol , vol.104 , Issue.4 , pp. 373-381
    • Newsome, D.A.1    Hewitt, A.T.2    Huh, W.3    Robey, P.G.4    Hassell, J.R.5
  • 92
  • 93
    • 0034012166 scopus 로고    scopus 로고
    • Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
    • R.F. Mullins, S.R. Russell, D.H. Anderson, and G.S. Hageman Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease FASEB J 14 7 2000 835 846
    • (2000) FASEB J , vol.14 , Issue.7 , pp. 835-846
    • Mullins, R.F.1    Russell, S.R.2    Anderson, D.H.3    Hageman, G.S.4
  • 94
    • 77249147331 scopus 로고    scopus 로고
    • The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
    • D.H. Anderson, M.J. Radeke, and N.B. Gallo The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited Prog Retin Eye Res 29 2 2010 95 112
    • (2010) Prog Retin Eye Res , vol.29 , Issue.2 , pp. 95-112
    • Anderson, D.H.1    Radeke, M.J.2    Gallo, N.B.3
  • 95
    • 0344676389 scopus 로고    scopus 로고
    • An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
    • J. Ambati, A. Anand, and S. Fernandez An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice Nat Med 9 11 2003 1390 1397
    • (2003) Nat Med , vol.9 , Issue.11 , pp. 1390-1397
    • Ambati, J.1    Anand, A.2    Fernandez, S.3
  • 96
    • 73349097249 scopus 로고    scopus 로고
    • The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages
    • U.F. Luhmann, S. Robbie, and P.M. Munro The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages Invest Ophthalmol Vis Sci 50 12 2009 5934 5943
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.12 , pp. 5934-5943
    • Luhmann, U.F.1    Robbie, S.2    Munro, P.M.3
  • 97
    • 84860389425 scopus 로고    scopus 로고
    • Cellular and 3D optical coherence tomography assessment during the initiation and progression of retinal degeneration in the Ccl2/Cx3cr1-deficient mouse
    • Y. Zhou, K.G. Sheets, and E.J. Knott Cellular and 3D optical coherence tomography assessment during the initiation and progression of retinal degeneration in the Ccl2/Cx3cr1-deficient mouse Exp Eye Res 93 5 2011 636 648
    • (2011) Exp Eye Res , vol.93 , Issue.5 , pp. 636-648
    • Zhou, Y.1    Sheets, K.G.2    Knott, E.J.3
  • 98
    • 84860179093 scopus 로고    scopus 로고
    • Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling
    • U.F. Luhmann, C.A. Lange, and S. Robbie Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling PLoS One 7 4 2012 e35551
    • (2012) PLoS One , vol.7 , Issue.4 , pp. 35551
    • Luhmann, U.F.1    Lange, C.A.2    Robbie, S.3
  • 99
    • 84863723643 scopus 로고    scopus 로고
    • The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes
    • M.J. Mattapallil, E.F. Wawrousek, and C.C. Chan The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes Invest Ophthalmol Vis Sci 53 6 2012 2921 2927
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.6 , pp. 2921-2927
    • Mattapallil, M.J.1    Wawrousek, E.F.2    Chan, C.C.3
  • 100
    • 79952159132 scopus 로고    scopus 로고
    • Emerging inflammasome effector mechanisms
    • M. Lamkanfi Emerging inflammasome effector mechanisms Nat Rev Immunol 11 3 2011 213 220
    • (2011) Nat Rev Immunol , vol.11 , Issue.3 , pp. 213-220
    • Lamkanfi, M.1
  • 101
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • O. Takeuchi, and S. Akira Pattern recognition receptors and inflammation Cell 140 6 2010 805 820
    • (2010) Cell , vol.140 , Issue.6 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 102
    • 79953203626 scopus 로고    scopus 로고
    • Inflammasome activation: From inflammatory disease to infection
    • A. Dunne Inflammasome activation: from inflammatory disease to infection Biochem Soc Trans 39 2 2011 669 673
    • (2011) Biochem Soc Trans , vol.39 , Issue.2 , pp. 669-673
    • Dunne, A.1
  • 103
    • 84860883878 scopus 로고    scopus 로고
    • DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
    • V. Tarallo, Y. Hirano, and B.D. Gelfand DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Cell 149 4 2012 847 859
    • (2012) Cell , vol.149 , Issue.4 , pp. 847-859
    • Tarallo, V.1    Hirano, Y.2    Gelfand, B.D.3
  • 104
    • 84860671364 scopus 로고    scopus 로고
    • NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
    • S.L. Doyle, M. Campbell, and E. Ozaki NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components Nat Med 18 5 2012 791 798
    • (2012) Nat Med , vol.18 , Issue.5 , pp. 791-798
    • Doyle, S.L.1    Campbell, M.2    Ozaki, E.3
  • 105
    • 33947652164 scopus 로고    scopus 로고
    • Interleukin-18 regulates pathological intraocular neovascularization
    • H. Qiao, K.H. Sonoda, and Y. Ikeda Interleukin-18 regulates pathological intraocular neovascularization J Leukoc Biol 81 4 2007 1012 1021
    • (2007) J Leukoc Biol , vol.81 , Issue.4 , pp. 1012-1021
    • Qiao, H.1    Sonoda, K.H.2    Ikeda, Y.3
  • 106
    • 0043125643 scopus 로고    scopus 로고
    • VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization
    • S. Ishida, T. Usui, and K. Yamashiro VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization J Exp Med 198 3 2003 483 489
    • (2003) J Exp Med , vol.198 , Issue.3 , pp. 483-489
    • Ishida, S.1    Usui, T.2    Yamashiro, K.3
  • 107
    • 77955883153 scopus 로고    scopus 로고
    • Complement: A key system for immune surveillance and homeostasis
    • D. Ricklin, G. Hajishengallis, K. Yang, and J.D. Lambris Complement: a key system for immune surveillance and homeostasis Nat Immunol 11 9 2010 785 797
    • (2010) Nat Immunol , vol.11 , Issue.9 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 108
    • 84861163710 scopus 로고    scopus 로고
    • Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9
    • M.A. Hadders, D. Bubeck, and P. Roversi Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9 Cell Rep 1 2012 1 8
    • (2012) Cell Rep , vol.1 , pp. 1-8
    • Hadders, M.A.1    Bubeck, D.2    Roversi, P.3
  • 109
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • J.L. Haines, M.A. Hauser, and S. Schmidt Complement factor H variant increases the risk of age-related macular degeneration Science 308 5720 2005 419 421
    • (2005) Science , vol.308 , Issue.5720 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3
  • 111
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • R.J. Klein, C. Zeiss, and E.Y. Chew Complement factor H polymorphism in age-related macular degeneration Science 308 5720 2005 385 389
    • (2005) Science , vol.308 , Issue.5720 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 112
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • G.S. Hageman, D.H. Anderson, and L.V. Johnson A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc Natl Acad Sci U S A 102 20 2005 7227 7232
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.20 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3
  • 113
    • 20544471911 scopus 로고    scopus 로고
    • Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration
    • S. Zareparsi, K.E. Branham, and M. Li Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration Am J Hum Genet 77 1 2005 149 153
    • (2005) Am J Hum Genet , vol.77 , Issue.1 , pp. 149-153
    • Zareparsi, S.1    Branham, K.E.2    Li, M.3
  • 114
    • 81055130123 scopus 로고    scopus 로고
    • Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration
    • L.V. Johnson, D.L. Forest, and C.D. Banna Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration Proc Natl Acad Sci U S A 108 45 2011 18277 18282
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.45 , pp. 18277-18282
    • Johnson, L.V.1    Forest, D.L.2    Banna, C.D.3
  • 115
    • 33144488589 scopus 로고    scopus 로고
    • Drusen complement components C3a and C5a promote choroidal neovascularization
    • M. Nozaki, B.J. Raisler, and E. Sakurai Drusen complement components C3a and C5a promote choroidal neovascularization Proc Natl Acad Sci U S A 103 7 2006 2328 2333
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.7 , pp. 2328-2333
    • Nozaki, M.1    Raisler, B.J.2    Sakurai, E.3
  • 116
    • 77955658951 scopus 로고    scopus 로고
    • C5a promotes migration, proliferation, and vessel formation in endothelial cells
    • R. Kurihara, K. Yamaoka, and N. Sawamukai C5a promotes migration, proliferation, and vessel formation in endothelial cells Inflamm Res 59 8 2010 659 666
    • (2010) Inflamm Res , vol.59 , Issue.8 , pp. 659-666
    • Kurihara, R.1    Yamaoka, K.2    Sawamukai, N.3
  • 117
    • 59449090281 scopus 로고    scopus 로고
    • C5a, but not C3a, increases VEGF secretion in ARPE-19 human retinal pigment epithelial cells
    • D.N. Cortright, R. Meade, S.M. Waters, B.L. Chenard, and J.E. Krause C5a, but not C3a, increases VEGF secretion in ARPE-19 human retinal pigment epithelial cells Curr Eye Res 34 1 2009 57 61
    • (2009) Curr Eye Res , vol.34 , Issue.1 , pp. 57-61
    • Cortright, D.N.1    Meade, R.2    Waters, S.M.3    Chenard, B.L.4    Krause, J.E.5
  • 118
    • 10844231850 scopus 로고    scopus 로고
    • Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization
    • P.S. Bora, J.H. Sohn, and J.M. Cruz Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization J Immunol 174 1 2005 491 497
    • (2005) J Immunol , vol.174 , Issue.1 , pp. 491-497
    • Bora, P.S.1    Sohn, J.H.2    Cruz, J.M.3
  • 119
    • 33746190776 scopus 로고    scopus 로고
    • Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: Role of factor B and factor H
    • N.S. Bora, S. Kaliappan, and P. Jha Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H J Immunol 177 3 2006 1872 1878
    • (2006) J Immunol , vol.177 , Issue.3 , pp. 1872-1878
    • Bora, N.S.1    Kaliappan, S.2    Jha, P.3
  • 120
    • 33846507393 scopus 로고    scopus 로고
    • CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration
    • N.S. Bora, S. Kaliappan, and P. Jha CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration J Immunol 178 3 2007 1783 1790
    • (2007) J Immunol , vol.178 , Issue.3 , pp. 1783-1790
    • Bora, N.S.1    Kaliappan, S.2    Jha, P.3
  • 121
    • 79951551543 scopus 로고    scopus 로고
    • The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization
    • B. Rohrer, B. Coughlin, and K. Kunchithapautham The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization Mol Immunol 48 6-7 2011 e1 e8
    • (2011) Mol Immunol , vol.48 , Issue.67
    • Rohrer, B.1    Coughlin, B.2    Kunchithapautham, K.3
  • 122
    • 79955721853 scopus 로고    scopus 로고
    • A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration
    • S.M. Cashman, K. Ramo, and R. Kumar-Singh A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration PLoS One 6 4 2011 e19078
    • (2011) PLoS One , vol.6 , Issue.4 , pp. 19078
    • Cashman, S.M.1    Ramo, K.2    Kumar-Singh, R.3
  • 123
    • 67649989567 scopus 로고    scopus 로고
    • A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration
    • B. Rohrer, Q. Long, and B. Coughlin A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration Invest Ophthalmol Vis Sci 50 7 2009 3056 3064
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.7 , pp. 3056-3064
    • Rohrer, B.1    Long, Q.2    Coughlin, B.3
  • 124
    • 78649482676 scopus 로고    scopus 로고
    • Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis
    • H.F. Langer, K.J. Chung, and V.V. Orlova Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis Blood 116 22 2010 4395 4403
    • (2010) Blood , vol.116 , Issue.22 , pp. 4395-4403
    • Langer, H.F.1    Chung, K.J.2    Orlova, V.V.3
  • 125
    • 23944468114 scopus 로고    scopus 로고
    • Membranoproliferative glomerulonephritis type II (dense deposit disease): An update
    • G.B. Appel, H.T. Cook, and G. Hageman Membranoproliferative glomerulonephritis type II (dense deposit disease): an update J Am Soc Nephrol 16 5 2005 1392 1403
    • (2005) J Am Soc Nephrol , vol.16 , Issue.5 , pp. 1392-1403
    • Appel, G.B.1    Cook, H.T.2    Hageman, G.3
  • 126
    • 84872021668 scopus 로고    scopus 로고
    • Vascular endothelial growth factor A in intraocular vascular disease
    • Miller JW, Le Couter J, Strauss EC, Ferrara N. Vascular endothelial growth factor A in intraocular vascular disease. Ophthalmology. doi:10.1016/j.ophtha.2012.07.038.
    • Ophthalmology
    • Miller, J.W.1    Le Couter, J.2    Strauss, E.C.3    Ferrara, N.4
  • 127
    • 78650718758 scopus 로고    scopus 로고
    • Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
    • G. Trichonas, Y. Murakami, and A. Thanos Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis Proc Natl Acad Sci U S A 107 50 2010 21695 21700
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.50 , pp. 21695-21700
    • Trichonas, G.1    Murakami, Y.2    Thanos, A.3
  • 128
    • 84865973897 scopus 로고    scopus 로고
    • Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration
    • Y. Murakami, H. Matsumoto, and M. Roh Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration Proc Natl Acad Sci U S A 109 36 2012 14598 14603
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.36 , pp. 14598-14603
    • Murakami, Y.1    Matsumoto, H.2    Roh, M.3
  • 129
    • 0017327013 scopus 로고
    • The inheritance of senile macule degeneration
    • J. Francois [The inheritance of senile macule degeneration] Ophthalmologica 175 2 1977 67 72
    • (1977) Ophthalmologica , vol.175 , Issue.2 , pp. 67-72
    • Francois, J.1
  • 130
    • 0028033697 scopus 로고
    • Is genetic predisposition an important risk factor in age-related macular degeneration?
    • G. Silvestri, P.B. Johnston, and A.E. Hughes Is genetic predisposition an important risk factor in age-related macular degeneration? Eye (Lond) 8 Pt 5 1994 564 568
    • (1994) Eye (Lond) , vol.8 , Issue.PART 5 , pp. 564-568
    • Silvestri, G.1    Johnston, P.B.2    Hughes, A.E.3
  • 131
    • 0031022320 scopus 로고    scopus 로고
    • Familial aggregation of age-related maculopathy
    • J.M. Seddon, U.A. Ajani, and B.D. Mitchell Familial aggregation of age-related maculopathy Am J Ophthalmol 123 2 1997 199 206
    • (1997) Am J Ophthalmol , vol.123 , Issue.2 , pp. 199-206
    • Seddon, J.M.1    Ajani, U.A.2    Mitchell, B.D.3
  • 132
  • 133
    • 0028875171 scopus 로고
    • A twin study of age-related macular degeneration
    • S.M. Meyers, T. Greene, and F.A. Gutman A twin study of age-related macular degeneration Am J Ophthalmol 120 6 1995 757 766
    • (1995) Am J Ophthalmol , vol.120 , Issue.6 , pp. 757-766
    • Meyers, S.M.1    Greene, T.2    Gutman, F.A.3
  • 134
    • 38749154667 scopus 로고    scopus 로고
    • Familial aggregation of age-related macular degeneration in the Utah population
    • L. Luo, J. Harmon, and X. Yang Familial aggregation of age-related macular degeneration in the Utah population Vision Res 48 3 2008 494 500
    • (2008) Vision Res , vol.48 , Issue.3 , pp. 494-500
    • Luo, L.1    Harmon, J.2    Yang, X.3
  • 135
    • 79957604976 scopus 로고    scopus 로고
    • Genetics of age-related macular degeneration: Current concepts, future directions
    • M.M. Deangelis, A.C. Silveira, E.A. Carr, and I.K. Kim Genetics of age-related macular degeneration: current concepts, future directions Semin Ophthalmol 26 3 2011 77 93
    • (2011) Semin Ophthalmol , vol.26 , Issue.3 , pp. 77-93
    • Deangelis, M.M.1    Silveira, A.C.2    Carr, E.A.3    Kim, I.K.4
  • 136
    • 11144354339 scopus 로고    scopus 로고
    • Prevalence of age-related macular degeneration in the United States
    • D.S. Friedman, B.J. O'Colmain, and B. Munoz Prevalence of age-related macular degeneration in the United States Arch Ophthalmol 122 4 2004 564 572
    • (2004) Arch Ophthalmol , vol.122 , Issue.4 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Munoz, B.3
  • 137
    • 79955050748 scopus 로고    scopus 로고
    • Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings
    • R.L. Ufret-Vincenty, B. Aredo, and X. Liu Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings Invest Ophthalmol Vis Sci 51 11 2010 5878 5887
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.11 , pp. 5878-5887
    • Ufret-Vincenty, R.L.1    Aredo, B.2    Liu, X.3
  • 138
    • 33746041795 scopus 로고    scopus 로고
    • Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration
    • D.D. Despriet, C.C. Klaver, and J.C. Witteman Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration JAMA 296 3 2006 301 309
    • (2006) JAMA , vol.296 , Issue.3 , pp. 301-309
    • Despriet, D.D.1    Klaver, C.C.2    Witteman, J.C.3
  • 139
    • 33748752137 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration
    • A. Thakkinstian, P. Han, and M. McEvoy Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration Hum Mol Genet 15 18 2006 2784 2790
    • (2006) Hum Mol Genet , vol.15 , Issue.18 , pp. 2784-2790
    • Thakkinstian, A.1    Han, P.2    McEvoy, M.3
  • 140
    • 34548418473 scopus 로고    scopus 로고
    • Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes
    • C.L. Thompson, B.E. Klein, and R. Klein Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes Hum Mol Genet 16 17 2007 2135 2148
    • (2007) Hum Mol Genet , vol.16 , Issue.17 , pp. 2135-2148
    • Thompson, C.L.1    Klein, B.E.2    Klein, R.3
  • 141
    • 79551507173 scopus 로고    scopus 로고
    • Complement factor H Y402H variant and risk of age-related macular degeneration in Asians: A systematic review and meta-analysis
    • N. Kondo, H. Bessho, S. Honda, and A. Negi Complement factor H Y402H variant and risk of age-related macular degeneration in Asians: a systematic review and meta-analysis Ophthalmology 118 2 2011 339 344
    • (2011) Ophthalmology , vol.118 , Issue.2 , pp. 339-344
    • Kondo, N.1    Bessho, H.2    Honda, S.3    Negi, A.4
  • 142
    • 84871195094 scopus 로고    scopus 로고
    • Association between complementary factor H Y402H polymorphisms and age-related macular degeneration in Chinese: Systematic review and meta-analysis
    • Y.L. Quan, A.Y. Zhou, and Z.H. Feng Association between complementary factor H Y402H polymorphisms and age-related macular degeneration in Chinese: systematic review and meta-analysis Int J Ophthalmol 5 2 2012 242 246
    • (2012) Int J Ophthalmol , vol.5 , Issue.2 , pp. 242-246
    • Quan, Y.L.1    Zhou, A.Y.2    Feng, Z.H.3
  • 143
    • 82255162545 scopus 로고    scopus 로고
    • A rare penetrant mutation in CFH confers high risk of age-related macular degeneration
    • S. Raychaudhuri, O. Iartchouk, and K. Chin A rare penetrant mutation in CFH confers high risk of age-related macular degeneration Nat Genet 43 12 2011 1232 1236
    • (2011) Nat Genet , vol.43 , Issue.12 , pp. 1232-1236
    • Raychaudhuri, S.1    Iartchouk, O.2    Chin, K.3
  • 144
    • 84859463748 scopus 로고    scopus 로고
    • Genetic associations in polypoidal choroidal vasculopathy: A systematic review and meta-analysis
    • H. Chen, K. Liu, L.J. Chen, P. Hou, W. Chen, and C.P. Pang Genetic associations in polypoidal choroidal vasculopathy: a systematic review and meta-analysis Mol Vis 18 2012 816 829
    • (2012) Mol Vis , vol.18 , pp. 816-829
    • Chen, H.1    Liu, K.2    Chen, L.J.3    Hou, P.4    Chen, W.5    Pang, C.P.6
  • 145
    • 47749126514 scopus 로고    scopus 로고
    • Factor H family proteins and human diseases
    • M. Jozsi, and P.F. Zipfel Factor H family proteins and human diseases Trends Immunol 29 8 2008 380 387
    • (2008) Trends Immunol , vol.29 , Issue.8 , pp. 380-387
    • Jozsi, M.1    Zipfel, P.F.2
  • 146
    • 70349441306 scopus 로고    scopus 로고
    • Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
    • S. Heinen, A. Hartmann, and N. Lauer Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation Blood 114 12 2009 2439 2447
    • (2009) Blood , vol.114 , Issue.12 , pp. 2439-2447
    • Heinen, S.1    Hartmann, A.2    Lauer, N.3
  • 147
    • 33749123246 scopus 로고    scopus 로고
    • A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
    • A.E. Hughes, N. Orr, H. Esfandiary, M. Diaz-Torres, T. Goodship, and U. Chakravarthy A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration Nat Genet 38 10 2006 1173 1177
    • (2006) Nat Genet , vol.38 , Issue.10 , pp. 1173-1177
    • Hughes, A.E.1    Orr, N.2    Esfandiary, H.3    Diaz-Torres, M.4    Goodship, T.5    Chakravarthy, U.6
  • 148
    • 77954094297 scopus 로고    scopus 로고
    • Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent
    • author reply 555-556
    • S. Raychaudhuri, S. Ripke, and M. Li Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent Nat Genet 42 7 2010 553 555 author reply 555-556
    • (2010) Nat Genet , vol.42 , Issue.7 , pp. 553-555
    • Raychaudhuri, S.1    Ripke, S.2    Li, M.3
  • 149
    • 84865847832 scopus 로고    scopus 로고
    • Comprehensive analysis of copy number variation of genes at chromosome 1 and 10 loci associated with late age related macular degeneration
    • S. Cantsilieris, S.J. White, A.J. Richardson, R.H. Guymer, and P.N. Baird Comprehensive analysis of copy number variation of genes at chromosome 1 and 10 loci associated with late age related macular degeneration PLoS One 7 4 2012 e35255
    • (2012) PLoS One , vol.7 , Issue.4 , pp. 35255
    • Cantsilieris, S.1    White, S.J.2    Richardson, A.J.3    Guymer, R.H.4    Baird, P.N.5
  • 150
    • 78149477844 scopus 로고    scopus 로고
    • Molecular intercommunication between the complement and coagulation systems
    • U. Amara, M.A. Flierl, and D. Rittirsch Molecular intercommunication between the complement and coagulation systems J Immunol 185 9 2010 5628 5636
    • (2010) J Immunol , vol.185 , Issue.9 , pp. 5628-5636
    • Amara, U.1    Flierl, M.A.2    Rittirsch, D.3
  • 151
    • 84859787228 scopus 로고    scopus 로고
    • Factor XIII and inflammatory cells
    • Z. Bagoly, E. Katona, and L. Muszbek Factor XIII and inflammatory cells Thromb Res 129 Suppl 2 2012 S77 S81
    • (2012) Thromb Res , vol.129 , Issue.SUPPL. 2
    • Bagoly, Z.1    Katona, E.2    Muszbek, L.3
  • 152
    • 46249093921 scopus 로고    scopus 로고
    • The NEI/NCBI dbGAP database: Genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration
    • H. Zhang, M.A. Morrison, and A. Dewan The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration BMC Med Genet 9 2008 51
    • (2008) BMC Med Genet , vol.9 , pp. 51
    • Zhang, H.1    Morrison, M.A.2    Dewan, A.3
  • 154
    • 84867214110 scopus 로고    scopus 로고
    • Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production
    • I. Landego, N. Jayachandran, and S. Wullschleger Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production Eur J Immunol 42 10 2012 2760 2770
    • (2012) Eur J Immunol , vol.42 , Issue.10 , pp. 2760-2770
    • Landego, I.1    Jayachandran, N.2    Wullschleger, S.3
  • 155
    • 75749140621 scopus 로고    scopus 로고
    • ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations
    • E. Kortvely, S.M. Hauck, and G. Duetsch ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations Invest Ophthalmol Vis Sci 51 1 2010 79 88
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.1 , pp. 79-88
    • Kortvely, E.1    Hauck, S.M.2    Duetsch, G.3
  • 156
    • 36049042661 scopus 로고    scopus 로고
    • A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
    • A. Kanda, W. Chen, and M. Othman A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration Proc Natl Acad Sci U S A 104 41 2007 16227 16232
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.41 , pp. 16227-16232
    • Kanda, A.1    Chen, W.2    Othman, M.3
  • 157
    • 46249098503 scopus 로고    scopus 로고
    • Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
    • L.G. Fritsche, T. Loenhardt, and A. Janssen Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA Nat Genet 40 7 2008 892 896
    • (2008) Nat Genet , vol.40 , Issue.7 , pp. 892-896
    • Fritsche, L.G.1    Loenhardt, T.2    Janssen, A.3
  • 158
    • 77956571785 scopus 로고    scopus 로고
    • The importance of mitochondria in age-related and inherited eye disorders
    • S.G. Jarrett, A.S. Lewin, and M.E. Boulton The importance of mitochondria in age-related and inherited eye disorders Ophthalmic Res 44 3 2010 179 190
    • (2010) Ophthalmic Res , vol.44 , Issue.3 , pp. 179-190
    • Jarrett, S.G.1    Lewin, A.S.2    Boulton, M.E.3
  • 159
    • 33751011889 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism in wet age-related macular degeneration
    • A. Dewan, M. Liu, and S. Hartman HTRA1 promoter polymorphism in wet age-related macular degeneration Science 314 5801 2006 989 992
    • (2006) Science , vol.314 , Issue.5801 , pp. 989-992
    • Dewan, A.1    Liu, M.2    Hartman, S.3
  • 160
    • 33751004690 scopus 로고    scopus 로고
    • A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
    • Z. Yang, N.J. Camp, and H. Sun A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration Science 314 5801 2006 992 993
    • (2006) Science , vol.314 , Issue.5801 , pp. 992-993
    • Yang, Z.1    Camp, N.J.2    Sun, H.3
  • 161
    • 80052302059 scopus 로고    scopus 로고
    • Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice
    • A. Jones, S. Kumar, and N. Zhang Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice Proc Natl Acad Sci U S A 108 35 2011 14578 14583
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.35 , pp. 14578-14583
    • Jones, A.1    Kumar, S.2    Zhang, N.3
  • 162
    • 79951967246 scopus 로고    scopus 로고
    • HTRA proteases: Regulated proteolysis in protein quality control
    • T. Clausen, M. Kaiser, R. Huber, and M. Ehrmann HTRA proteases: regulated proteolysis in protein quality control Nat Rev Mol Cell Biol 12 3 2011 152 162
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.3 , pp. 152-162
    • Clausen, T.1    Kaiser, M.2    Huber, R.3    Ehrmann, M.4
  • 163
    • 79960983554 scopus 로고    scopus 로고
    • Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components
    • S. Vierkotten, P.S. Muether, and S. Fauser Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components PLoS One 6 8 2011 e22959
    • (2011) PLoS One , vol.6 , Issue.8 , pp. 22959
    • Vierkotten, S.1    Muether, P.S.2    Fauser, S.3
  • 164
    • 0030566837 scopus 로고    scopus 로고
    • Primary structure of a putative serine protease specific for IGF-binding proteins
    • J. Zumbrunn, and B. Trueb Primary structure of a putative serine protease specific for IGF-binding proteins FEBS Lett 398 2-3 1996 187 192
    • (1996) FEBS Lett , vol.398 , Issue.23 , pp. 187-192
    • Zumbrunn, J.1    Trueb, B.2
  • 165
    • 40749128979 scopus 로고    scopus 로고
    • IGF2: Epigenetic regulation and role in development and disease
    • W. Chao, and P.A. D'Amore IGF2: epigenetic regulation and role in development and disease Cytokine Growth Factor Rev 19 2 2008 111 120
    • (2008) Cytokine Growth Factor Rev , vol.19 , Issue.2 , pp. 111-120
    • Chao, W.1    D'Amore, P.A.2
  • 166
    • 84865680259 scopus 로고    scopus 로고
    • Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes
    • L. Sobrin, S. Ripke, and Y. Yu Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes Ophthalmology 119 9 2012 1874 1885
    • (2012) Ophthalmology , vol.119 , Issue.9 , pp. 1874-1885
    • Sobrin, L.1    Ripke, S.2    Yu, Y.3
  • 167
    • 84862939642 scopus 로고    scopus 로고
    • High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-beta family member growth differentiation factor 6
    • L. Zhang, S.L. Lim, and H. Du High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-beta family member growth differentiation factor 6 J Biol Chem 287 2 2012 1520 1526
    • (2012) J Biol Chem , vol.287 , Issue.2 , pp. 1520-1526
    • Zhang, L.1    Lim, S.L.2    Du, H.3
  • 168
    • 49949115930 scopus 로고    scopus 로고
    • HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival
    • S. Launay, E. Maubert, and N. Lebeurrier HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival Cell Death Differ 15 9 2008 1408 1416
    • (2008) Cell Death Differ , vol.15 , Issue.9 , pp. 1408-1416
    • Launay, S.1    Maubert, E.2    Lebeurrier, N.3
  • 169
    • 84862291060 scopus 로고    scopus 로고
    • Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates
    • A. Tennstaedt, S. Popsel, and L. Truebestein Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates J Biol Chem 287 25 2012 20931 20941
    • (2012) J Biol Chem , vol.287 , Issue.25 , pp. 20931-20941
    • Tennstaedt, A.1    Popsel, S.2    Truebestein, L.3
  • 170
    • 0028833332 scopus 로고
    • Immunoreactivity against tau, amyloid precursor protein, and beta-amyloid in the human retina
    • K.U. Loffler, D.P. Edward, and M.O. Tso Immunoreactivity against tau, amyloid precursor protein, and beta-amyloid in the human retina Invest Ophthalmol Vis Sci 36 1 1995 24 31
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , Issue.1 , pp. 24-31
    • Loffler, K.U.1    Edward, D.P.2    Tso, M.O.3
  • 171
    • 84859024248 scopus 로고    scopus 로고
    • CFB/C2 gene polymorphisms and risk of age-related macular degeneration: A systematic review and meta-analysis
    • C. Sun, M. Zhao, and X. Li CFB/C2 gene polymorphisms and risk of age-related macular degeneration: a systematic review and meta-analysis Curr Eye Res 37 4 2012 259 271
    • (2012) Curr Eye Res , vol.37 , Issue.4 , pp. 259-271
    • Sun, C.1    Zhao, M.2    Li, X.3
  • 172
    • 84865776603 scopus 로고    scopus 로고
    • The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis
    • A. Thakkinstian, M. McEvoy, and U. Chakravarthy The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysis Am J Epidemiol 176 5 2012 361 372
    • (2012) Am J Epidemiol , vol.176 , Issue.5 , pp. 361-372
    • Thakkinstian, A.1    McEvoy, M.2    Chakravarthy, U.3
  • 173
    • 77953162265 scopus 로고    scopus 로고
    • Quantitative proteomics: Comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes
    • X. Yuan, X. Gu, and J.S. Crabb Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes Mol Cell Proteomics 9 6 2010 1031 1046
    • (2010) Mol Cell Proteomics , vol.9 , Issue.6 , pp. 1031-1046
    • Yuan, X.1    Gu, X.2    Crabb, J.S.3
  • 174
    • 33750141410 scopus 로고    scopus 로고
    • Secreted proteome profiling in human RPE cell cultures derived from donors with age related macular degeneration and age matched healthy donors
    • E. An, X. Lu, and J. Flippin Secreted proteome profiling in human RPE cell cultures derived from donors with age related macular degeneration and age matched healthy donors J Proteome Res 5 10 2006 2599 2610
    • (2006) J Proteome Res , vol.5 , Issue.10 , pp. 2599-2610
    • An, E.1    Lu, X.2    Flippin, J.3
  • 175
    • 79958789920 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: A HuGE review and meta-analysis
    • A. Thakkinstian, G.J. McKay, and M. McEvoy Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: a HuGE review and meta-analysis Am J Epidemiol 173 12 2011 1365 1379
    • (2011) Am J Epidemiol , vol.173 , Issue.12 , pp. 1365-1379
    • Thakkinstian, A.1    McKay, G.J.2    McEvoy, M.3
  • 177
    • 80052196120 scopus 로고    scopus 로고
    • Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration
    • Y. Yu, T.R. Bhangale, and J. Fagerness Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration Hum Mol Genet 20 18 2011 3699 3709
    • (2011) Hum Mol Genet , vol.20 , Issue.18 , pp. 3699-3709
    • Yu, Y.1    Bhangale, T.R.2    Fagerness, J.3
  • 178
    • 70349471089 scopus 로고    scopus 로고
    • Localization of complement 1 inhibitor (C1INH/SERPING1) in human eyes with age-related macular degeneration
    • R.F. Mullins, E.A. Faidley, H.T. Daggett, C. Jomary, A.J. Lotery, and E.M. Stone Localization of complement 1 inhibitor (C1INH/SERPING1) in human eyes with age-related macular degeneration Exp Eye Res 89 5 2009 767 773
    • (2009) Exp Eye Res , vol.89 , Issue.5 , pp. 767-773
    • Mullins, R.F.1    Faidley, E.A.2    Daggett, H.T.3    Jomary, C.4    Lotery, A.J.5    Stone, E.M.6
  • 179
    • 56249123595 scopus 로고    scopus 로고
    • Association between the SERPING1 gene and age-related macular degeneration: A two-stage case-control study
    • S. Ennis, C. Jomary, and R. Mullins Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study Lancet 372 9652 2008 1828 1834
    • (2008) Lancet , vol.372 , Issue.9652 , pp. 1828-1834
    • Ennis, S.1    Jomary, C.2    Mullins, R.3
  • 180
    • 80053590169 scopus 로고    scopus 로고
    • Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology
    • G. Jun, M. Nicolaou, and M.A. Morrison Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology PLoS One 6 10 2011 e25775
    • (2011) PLoS One , vol.6 , Issue.10 , pp. 25775
    • Jun, G.1    Nicolaou, M.2    Morrison, M.A.3
  • 181
    • 77950542695 scopus 로고    scopus 로고
    • Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
    • A.C. Silveira, M.A. Morrison, and F. Ji Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach Vision Res 50 7 2010 698 715
    • (2010) Vision Res , vol.50 , Issue.7 , pp. 698-715
    • Silveira, A.C.1    Morrison, M.A.2    Ji, F.3
  • 182
    • 78149483590 scopus 로고    scopus 로고
    • Prospective study of common variants in the retinoic acid receptor-related orphan receptor alpha gene and risk of neovascular age-related macular degeneration
    • D.A. Schaumberg, D. Chasman, and M.A. Morrison Prospective study of common variants in the retinoic acid receptor-related orphan receptor alpha gene and risk of neovascular age-related macular degeneration Arch Ophthalmol 128 11 2010 1462 1471
    • (2010) Arch Ophthalmol , vol.128 , Issue.11 , pp. 1462-1471
    • Schaumberg, D.A.1    Chasman, D.2    Morrison, M.A.3
  • 183
    • 0035095662 scopus 로고    scopus 로고
    • The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response
    • P. Delerive, D. Monte, and G. Dubois The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response EMBO Rep 2 1 2001 42 48
    • (2001) EMBO Rep , vol.2 , Issue.1 , pp. 42-48
    • Delerive, P.1    Monte, D.2    Dubois, G.3
  • 184
    • 1842423443 scopus 로고    scopus 로고
    • The "cholesteROR" protective pathway in the vascular system
    • F. Boukhtouche, J. Mariani, and A. Tedgui The "CholesteROR" protective pathway in the vascular system Arterioscler Thromb Vasc Biol 24 4 2004 637 643
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , Issue.4 , pp. 637-643
    • Boukhtouche, F.1    Mariani, J.2    Tedgui, A.3
  • 185
    • 84861189139 scopus 로고    scopus 로고
    • Retinoid-related orphan receptor alpha and the regulation of lipid homeostasis
    • R.L. Fitzsimmons, P. Lau, and G.E. Muscat Retinoid-related orphan receptor alpha and the regulation of lipid homeostasis J Steroid Biochem Mol Biol 130 3-5 2012 159 168
    • (2012) J Steroid Biochem Mol Biol , vol.130 , Issue.35 , pp. 159-168
    • Fitzsimmons, R.L.1    Lau, P.2    Muscat, G.E.3
  • 186
    • 9444283789 scopus 로고    scopus 로고
    • The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1
    • C. Chauvet, B. Bois-Joyeux, E. Berra, J. Pouyssegur, and J.L. Danan The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1 Biochem J 384 Pt 1 2004 79 85
    • (2004) Biochem J , vol.384 , Issue.PART 1 , pp. 79-85
    • Chauvet, C.1    Bois-Joyeux, B.2    Berra, E.3    Pouyssegur, J.4    Danan, J.L.5
  • 187
    • 0035824918 scopus 로고    scopus 로고
    • Increased ischemia-induced angiogenesis in the staggerer mouse, a mutant of the nuclear receptor Roralpha
    • S. Besnard, J.S. Silvestre, and M. Duriez Increased ischemia-induced angiogenesis in the staggerer mouse, a mutant of the nuclear receptor Roralpha Circ Res 89 12 2001 1209 1215
    • (2001) Circ Res , vol.89 , Issue.12 , pp. 1209-1215
    • Besnard, S.1    Silvestre, J.S.2    Duriez, M.3
  • 188
    • 33646706084 scopus 로고    scopus 로고
    • RORA, a large common fragile site gene, is involved in cellular stress response
    • Y. Zhu, S. McAvoy, R. Kuhn, and D.I. Smith RORA, a large common fragile site gene, is involved in cellular stress response Oncogene 25 20 2006 2901 2908
    • (2006) Oncogene , vol.25 , Issue.20 , pp. 2901-2908
    • Zhu, Y.1    McAvoy, S.2    Kuhn, R.3    Smith, D.I.4
  • 189
    • 9444220221 scopus 로고    scopus 로고
    • The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration
    • J. Tuo, B.C. Smith, and C.M. Bojanowski The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration FASEB J 18 11 2004 1297 1299
    • (2004) FASEB J , vol.18 , Issue.11 , pp. 1297-1299
    • Tuo, J.1    Smith, B.C.2    Bojanowski, C.M.3
  • 190
    • 34948898131 scopus 로고    scopus 로고
    • CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration
    • C. Combadiere, C. Feumi, and W. Raoul CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration J Clin Invest 117 10 2007 2920 2928
    • (2007) J Clin Invest , vol.117 , Issue.10 , pp. 2920-2928
    • Combadiere, C.1    Feumi, C.2    Raoul, W.3
  • 191
    • 34648846532 scopus 로고    scopus 로고
    • Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration
    • J. Tuo, C.M. Bojanowski, and M. Zhou Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration Invest Ophthalmol Vis Sci 48 8 2007 3827 3836
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , Issue.8 , pp. 3827-3836
    • Tuo, J.1    Bojanowski, C.M.2    Zhou, M.3
  • 192
    • 84868136294 scopus 로고    scopus 로고
    • Enhanced apoptosis in retinal pigment epithelium under inflammatory stimuli and oxidative stress
    • Y. Wang, D. Shen, and V.M. Wang Enhanced apoptosis in retinal pigment epithelium under inflammatory stimuli and oxidative stress Apoptosis 17 11 2012 1144 1155
    • (2012) Apoptosis , vol.17 , Issue.11 , pp. 1144-1155
    • Wang, Y.1    Shen, D.2    Wang, V.M.3
  • 193
    • 56149112376 scopus 로고    scopus 로고
    • Age-related macular degeneration is associated with the HLA-Cw*0701 genotype and the natural killer cell receptor AA haplotype
    • S.V. Goverdhan, S.I. Khakoo, H. Gaston, X. Chen, and A.J. Lotery Age-related macular degeneration is associated with the HLA-Cw*0701 genotype and the natural killer cell receptor AA haplotype Invest Ophthalmol Vis Sci 49 11 2008 5077 5082
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.11 , pp. 5077-5082
    • Goverdhan, S.V.1    Khakoo, S.I.2    Gaston, H.3    Chen, X.4    Lotery, A.J.5
  • 194
    • 62549142650 scopus 로고    scopus 로고
    • Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling
    • K.W. Leung, C.J. Barnstable, and J. Tombran-Tink Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling Mol Immunol 46 7 2009 1374 1386
    • (2009) Mol Immunol , vol.46 , Issue.7 , pp. 1374-1386
    • Leung, K.W.1    Barnstable, C.J.2    Tombran-Tink, J.3
  • 195
    • 84864404796 scopus 로고    scopus 로고
    • Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration
    • J.B. Jonas, Y. Tao, M. Neumaier, and P. Findeisen Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration Acta Ophthalmol 90 5 2012 e381 e388
    • (2012) Acta Ophthalmol , vol.90 , Issue.5
    • Jonas, J.B.1    Tao, Y.2    Neumaier, M.3    Findeisen, P.4
  • 196
    • 41849107208 scopus 로고    scopus 로고
    • Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration
    • S.V. Goverdhan, S. Ennis, and S.R. Hannan Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration Br J Ophthalmol 92 4 2008 537 540
    • (2008) Br J Ophthalmol , vol.92 , Issue.4 , pp. 537-540
    • Goverdhan, S.V.1    Ennis, S.2    Hannan, S.R.3
  • 197
    • 54849148000 scopus 로고    scopus 로고
    • Toll-like receptor 3 and geographic atrophy in age-related macular degeneration
    • Z. Yang, C. Stratton, and P.J. Francis Toll-like receptor 3 and geographic atrophy in age-related macular degeneration N Engl J Med 359 14 2008 1456 1463
    • (2008) N Engl J Med , vol.359 , Issue.14 , pp. 1456-1463
    • Yang, Z.1    Stratton, C.2    Francis, P.J.3
  • 198
    • 20544433415 scopus 로고    scopus 로고
    • Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration
    • S. Zareparsi, M. Buraczynska, and K.E. Branham Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration Hum Mol Genet 14 11 2005 1449 1455
    • (2005) Hum Mol Genet , vol.14 , Issue.11 , pp. 1449-1455
    • Zareparsi, S.1    Buraczynska, M.2    Branham, K.E.3
  • 199
    • 0037050030 scopus 로고    scopus 로고
    • Fibulin-5/DANCE is essential for elastogenesis in vivo
    • T. Nakamura, P.R. Lozano, and Y. Ikeda Fibulin-5/DANCE is essential for elastogenesis in vivo Nature 415 6868 2002 171 175
    • (2002) Nature , vol.415 , Issue.6868 , pp. 171-175
    • Nakamura, T.1    Lozano, P.R.2    Ikeda, Y.3
  • 200
    • 0037049996 scopus 로고    scopus 로고
    • Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo
    • H. Yanagisawa, E.C. Davis, and B.C. Starcher Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo Nature 415 6868 2002 168 171
    • (2002) Nature , vol.415 , Issue.6868 , pp. 168-171
    • Yanagisawa, H.1    Davis, E.C.2    Starcher, B.C.3
  • 201
    • 33845682603 scopus 로고    scopus 로고
    • Fibulin-5 distribution in human eyes: Relevance to age-related macular degeneration
    • R.F. Mullins, M.A. Olvera, A.F. Clark, and E.M. Stone Fibulin-5 distribution in human eyes: relevance to age-related macular degeneration Exp Eye Res 84 2 2007 378 380
    • (2007) Exp Eye Res , vol.84 , Issue.2 , pp. 378-380
    • Mullins, R.F.1    Olvera, M.A.2    Clark, A.F.3    Stone, E.M.4
  • 202
    • 20044379927 scopus 로고    scopus 로고
    • Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration
    • J.A. Spencer, S.L. Hacker, and E.C. Davis Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration Proc Natl Acad Sci U S A 102 8 2005 2946 2951
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.8 , pp. 2946-2951
    • Spencer, J.A.1    Hacker, S.L.2    Davis, E.C.3
  • 203
    • 0032468842 scopus 로고    scopus 로고
    • Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q
    • M.L. Klein, D.W. Schultz, and A. Edwards Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q Arch Ophthalmol 116 8 1998 1082 1088
    • (1998) Arch Ophthalmol , vol.116 , Issue.8 , pp. 1082-1088
    • Klein, M.L.1    Schultz, D.W.2    Edwards, A.3
  • 204
    • 0348013124 scopus 로고    scopus 로고
    • Analysis of the ARMD1 locus: Evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family
    • D.W. Schultz, M.L. Klein, and A.J. Humpert Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family Hum Mol Genet 12 24 2003 3315 3323
    • (2003) Hum Mol Genet , vol.12 , Issue.24 , pp. 3315-3323
    • Schultz, D.W.1    Klein, M.L.2    Humpert, A.J.3
  • 205
    • 0033027071 scopus 로고    scopus 로고
    • A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy
    • E.M. Stone, A.J. Lotery, and F.L. Munier A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy Nat Genet 22 2 1999 199 202
    • (1999) Nat Genet , vol.22 , Issue.2 , pp. 199-202
    • Stone, E.M.1    Lotery, A.J.2    Munier, F.L.3
  • 206
    • 60549101748 scopus 로고    scopus 로고
    • Serum cystatin C level, kidney disease markers, and incidence of age-related macular degeneration: The Beaver Dam Eye Study
    • R. Klein, M.D. Knudtson, K.E. Lee, and B.E. Klein Serum cystatin C level, kidney disease markers, and incidence of age-related macular degeneration: the Beaver Dam Eye Study Arch Ophthalmol 127 2 2009 193 199
    • (2009) Arch Ophthalmol , vol.127 , Issue.2 , pp. 193-199
    • Klein, R.1    Knudtson, M.D.2    Lee, K.E.3    Klein, B.E.4
  • 207
    • 0036158627 scopus 로고    scopus 로고
    • CST3 genotype associated with exudative age related macular degeneration
    • J. Zurdel, U. Finckh, G. Menzer, R.M. Nitsch, and G. Richard CST3 genotype associated with exudative age related macular degeneration Br J Ophthalmol 86 2 2002 214 219
    • (2002) Br J Ophthalmol , vol.86 , Issue.2 , pp. 214-219
    • Zurdel, J.1    Finckh, U.2    Menzer, G.3    Nitsch, R.M.4    Richard, G.5
  • 208
    • 77149131537 scopus 로고    scopus 로고
    • Cystatin C protects neuronal cells from amyloid-beta-induced toxicity
    • B. Tizon, E.M. Ribe, W. Mi, C.M. Troy, and E. Levy Cystatin C protects neuronal cells from amyloid-beta-induced toxicity J Alzheimers Dis 19 3 2010 885 894
    • (2010) J Alzheimers Dis , vol.19 , Issue.3 , pp. 885-894
    • Tizon, B.1    Ribe, E.M.2    Mi, W.3    Troy, C.M.4    Levy, E.5
  • 209
    • 84859833392 scopus 로고    scopus 로고
    • Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling
    • N.E. Clarke, M.J. Fisher, K.E. Porter, D.W. Lambert, and A.J. Turner Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling PLoS One 7 4 2012 e34747
    • (2012) PLoS One , vol.7 , Issue.4 , pp. 34747
    • Clarke, N.E.1    Fisher, M.J.2    Porter, K.E.3    Lambert, D.W.4    Turner, A.J.5
  • 210
    • 0041924832 scopus 로고    scopus 로고
    • Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietin
    • S. Sarlos, B. Rizkalla, C.J. Moravski, Z. Cao, M.E. Cooper, and J.L. Wilkinson-Berka Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietin Am J Pathol 163 3 2003 879 887
    • (2003) Am J Pathol , vol.163 , Issue.3 , pp. 879-887
    • Sarlos, S.1    Rizkalla, B.2    Moravski, C.J.3    Cao, Z.4    Cooper, M.E.5    Wilkinson-Berka, J.L.6
  • 211
    • 0036311176 scopus 로고    scopus 로고
    • Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration
    • H.K. Hamdi, J. Reznik, and R. Castellon Alu DNA polymorphism in ACE gene is protective for age-related macular degeneration Biochem Biophys Res Commun 295 3 2002 668 672
    • (2002) Biochem Biophys Res Commun , vol.295 , Issue.3 , pp. 668-672
    • Hamdi, H.K.1    Reznik, J.2    Castellon, R.3
  • 212
    • 0037212317 scopus 로고    scopus 로고
    • Vascular collagens: Spotlight on the role of type VIII collagen in atherogenesis
    • G.A. Plenz, M.C. Deng, H. Robenek, and W. Volker Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis Atherosclerosis 166 1 2003 1 11
    • (2003) Atherosclerosis , vol.166 , Issue.1 , pp. 1-11
    • Plenz, G.A.1    Deng, M.C.2    Robenek, H.3    Volker, W.4
  • 213
    • 0027322874 scopus 로고
    • Angiogenic oligosaccharides of hyaluronan enhance the production of collagens by endothelial cells
    • P. Rooney, M. Wang, P. Kumar, and S. Kumar Angiogenic oligosaccharides of hyaluronan enhance the production of collagens by endothelial cells J Cell Sci 105 Pt 1 1993 213 218
    • (1993) J Cell Sci , vol.105 , Issue.PART 1 , pp. 213-218
    • Rooney, P.1    Wang, M.2    Kumar, P.3    Kumar, S.4
  • 214
    • 68049097903 scopus 로고    scopus 로고
    • Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium
    • K.G. Duncan, K. Hosseini, and K.R. Bailey Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium Br J Ophthalmol 93 8 2009 1116 1120
    • (2009) Br J Ophthalmol , vol.93 , Issue.8 , pp. 1116-1120
    • Duncan, K.G.1    Hosseini, K.2    Bailey, K.R.3
  • 215
    • 80052197495 scopus 로고    scopus 로고
    • Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration
    • Y. Yu, R. Reynolds, J. Fagerness, B. Rosner, M.J. Daly, and J.M. Seddon Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration Invest Ophthalmol Vis Sci 52 7 2011 4663 4670
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.7 , pp. 4663-4670
    • Yu, Y.1    Reynolds, R.2    Fagerness, J.3    Rosner, B.4    Daly, M.J.5    Seddon, J.M.6
  • 216
    • 55549115364 scopus 로고    scopus 로고
    • Retinopathy in mice induced by disrupted all-trans-retinal clearance
    • A. Maeda, T. Maeda, M. Golczak, and K. Palczewski Retinopathy in mice induced by disrupted all-trans-retinal clearance J Biol Chem 283 39 2008 26684 26693
    • (2008) J Biol Chem , vol.283 , Issue.39 , pp. 26684-26693
    • Maeda, A.1    Maeda, T.2    Golczak, M.3    Palczewski, K.4
  • 217
    • 0035853719 scopus 로고    scopus 로고
    • ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease
    • H. Sun, and J. Nathans ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease J Biol Chem 276 15 2001 11766 11774
    • (2001) J Biol Chem , vol.276 , Issue.15 , pp. 11766-11774
    • Sun, H.1    Nathans, J.2
  • 218
    • 84863304501 scopus 로고    scopus 로고
    • ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer
    • F. Quazi, S. Lenevich, and R.S. Molday ABCA4 is an N-retinylidene- phosphatidylethanolamine and phosphatidylethanolamine importer Nat Commun 3 2012 925
    • (2012) Nat Commun , vol.3 , pp. 925
    • Quazi, F.1    Lenevich, S.2    Molday, R.S.3
  • 219
    • 0031037951 scopus 로고    scopus 로고
    • A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy
    • R. Allikmets, N. Singh, and H. Sun A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy Nat Genet 15 3 1997 236 246
    • (1997) Nat Genet , vol.15 , Issue.3 , pp. 236-246
    • Allikmets, R.1    Singh, N.2    Sun, H.3
  • 220
    • 45449085894 scopus 로고    scopus 로고
    • Age-related macular degeneration: A perspective on genetic studies
    • N. Patel, T. Adewoyin, and N.V. Chong Age-related macular degeneration: a perspective on genetic studies Eye (Lond) 22 6 2008 768 776
    • (2008) Eye (Lond) , vol.22 , Issue.6 , pp. 768-776
    • Patel, N.1    Adewoyin, T.2    Chong, N.V.3
  • 221
    • 0033538438 scopus 로고    scopus 로고
    • Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice
    • J. Weng, N.L. Mata, S.M. Azarian, R.T. Tzekov, D.G. Birch, and G.H. Travis Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice Cell 98 1 1999 13 23
    • (1999) Cell , vol.98 , Issue.1 , pp. 13-23
    • Weng, J.1    Mata, N.L.2    Azarian, S.M.3    Tzekov, R.T.4    Birch, D.G.5    Travis, G.H.6
  • 222
    • 0034944895 scopus 로고    scopus 로고
    • Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: Implications for involvement of ABCR in age-related macular degeneration
    • N.L. Mata, R.T. Tzekov, X. Liu, J. Weng, D.G. Birch, and G.H. Travis Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration Invest Ophthalmol Vis Sci 42 8 2001 1685 1690
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.8 , pp. 1685-1690
    • Mata, N.L.1    Tzekov, R.T.2    Liu, X.3    Weng, J.4    Birch, D.G.5    Travis, G.H.6
  • 224
    • 0035703655 scopus 로고    scopus 로고
    • Visual function in patients with cone-rod dystrophy (CRD) associated with mutations in the ABCA4(ABCR) gene
    • D.G. Birch, A.Y. Peters, K.L. Locke, R. Spencer, C.F. Megarity, and G.H. Travis Visual function in patients with cone-rod dystrophy (CRD) associated with mutations in the ABCA4(ABCR) gene Exp Eye Res 73 6 2001 877 886
    • (2001) Exp Eye Res , vol.73 , Issue.6 , pp. 877-886
    • Birch, D.G.1    Peters, A.Y.2    Locke, K.L.3    Spencer, R.4    Megarity, C.F.5    Travis, G.H.6
  • 225
    • 33645808672 scopus 로고    scopus 로고
    • Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
    • R.W. Mahley, K.H. Weisgraber, and Y. Huang Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease Proc Natl Acad Sci U S A 103 15 2006 5644 5651
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.15 , pp. 5644-5651
    • Mahley, R.W.1    Weisgraber, K.H.2    Huang, Y.3
  • 226
    • 74649085042 scopus 로고    scopus 로고
    • Apolipoprotein e and its role in aging and survival
    • F. Bonomini, F. Filippini, and T. Hayek Apolipoprotein E and its role in aging and survival Exp Gerontol 45 2 2010 149 157
    • (2010) Exp Gerontol , vol.45 , Issue.2 , pp. 149-157
    • Bonomini, F.1    Filippini, F.2    Hayek, T.3
  • 227
    • 33750613413 scopus 로고    scopus 로고
    • Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors
    • N. Tserentsoodol, N.V. Gordiyenko, I. Pascual, J.W. Lee, S.J. Fliesler, and I.R. Rodriguez Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors Mol Vis 12 2006 1319 1333
    • (2006) Mol Vis , vol.12 , pp. 1319-1333
    • Tserentsoodol, N.1    Gordiyenko, N.V.2    Pascual, I.3    Lee, J.W.4    Fliesler, S.J.5    Rodriguez, I.R.6
  • 228
    • 34248541316 scopus 로고    scopus 로고
    • Association between vitamin D and age-related macular degeneration in the Third National Health and Nutrition Examination Survey, 1988 through 1994
    • N. Parekh, R.J. Chappell, A.E. Millen, D.M. Albert, and J.A. Mares Association between vitamin D and age-related macular degeneration in the Third National Health and Nutrition Examination Survey, 1988 through 1994 Arch Ophthalmol 125 5 2007 661 669
    • (2007) Arch Ophthalmol , vol.125 , Issue.5 , pp. 661-669
    • Parekh, N.1    Chappell, R.J.2    Millen, A.E.3    Albert, D.M.4    Mares, J.A.5
  • 229
    • 79952001956 scopus 로고    scopus 로고
    • Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D
    • A.V. Krishnan, and D. Feldman Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D Annu Rev Pharmacol Toxicol 51 2011 311 336
    • (2011) Annu Rev Pharmacol Toxicol , vol.51 , pp. 311-336
    • Krishnan, A.V.1    Feldman, D.2
  • 230
    • 84860642194 scopus 로고    scopus 로고
    • Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
    • M.A. Morrison, A.C. Silveira, and N. Huynh Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration Hum Genomics 5 6 2011 538 568
    • (2011) Hum Genomics , vol.5 , Issue.6 , pp. 538-568
    • Morrison, M.A.1    Silveira, A.C.2    Huynh, N.3
  • 231
    • 33750201885 scopus 로고    scopus 로고
    • CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses
    • Y.P. Conley, J. Jakobsdottir, and T. Mah CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses Hum Mol Genet 15 21 2006 3206 3218
    • (2006) Hum Mol Genet , vol.15 , Issue.21 , pp. 3206-3218
    • Conley, Y.P.1    Jakobsdottir, J.2    Mah, T.3
  • 232
    • 23944475451 scopus 로고    scopus 로고
    • Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy
    • Y.P. Conley, A. Thalamuthu, and J. Jakobsdottir Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy Hum Mol Genet 14 14 2005 1991 2002
    • (2005) Hum Mol Genet , vol.14 , Issue.14 , pp. 1991-2002
    • Conley, Y.P.1    Thalamuthu, A.2    Jakobsdottir, J.3
  • 233
    • 80053323728 scopus 로고    scopus 로고
    • Evaluation of serum lipid concentrations and genetic variants at high-density lipoprotein metabolism loci and TIMP3 in age-related macular degeneration
    • S. Fauser, D. Smailhodzic, and A. Caramoy Evaluation of serum lipid concentrations and genetic variants at high-density lipoprotein metabolism loci and TIMP3 in age-related macular degeneration Invest Ophthalmol Vis Sci 52 8 2011 5525 5528
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.8 , pp. 5525-5528
    • Fauser, S.1    Smailhodzic, D.2    Caramoy, A.3
  • 234
    • 33644843900 scopus 로고    scopus 로고
    • Functional candidate genes in age-related macular degeneration: Significant association with VEGF, VLDLR, and LRP6
    • J.L. Haines, N. Schnetz-Boutaud, and S. Schmidt Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6 Invest Ophthalmol Vis Sci 47 1 2006 329 335
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.1 , pp. 329-335
    • Haines, J.L.1    Schnetz-Boutaud, N.2    Schmidt, S.3
  • 235
    • 84871241278 scopus 로고    scopus 로고
    • Genetic, behavioral, and sociodemographic risk factors for second eye progression in age-related macular degeneration
    • Y.T. Lechanteur, J.P. van de Ven, and D. Smailhodzic Genetic, behavioral, and sociodemographic risk factors for second eye progression in age-related macular degeneration Invest Ophthalmol Vis Sci 53 9 2012 5846 5852
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.9 , pp. 5846-5852
    • Lechanteur, Y.T.1    Van De Ven, J.P.2    Smailhodzic, D.3
  • 236
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • D.W. Dawson, O.V. Volpert, and P. Gillis Pigment epithelium-derived factor: a potent inhibitor of angiogenesis Science 285 5425 1999 245 248
    • (1999) Science , vol.285 , Issue.5425 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3
  • 237
    • 0036329579 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration
    • N.M. Holekamp, N. Bouck, and O. Volpert Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration Am J Ophthalmol 134 2 2002 220 227
    • (2002) Am J Ophthalmol , vol.134 , Issue.2 , pp. 220-227
    • Holekamp, N.M.1    Bouck, N.2    Volpert, O.3
  • 238
    • 40849135678 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor gene Met72Thr polymorphism is associated with increased risk of wet age-related macular degeneration
    • J.M. Lin, L. Wan, and Y.Y. Tsai Pigment epithelium-derived factor gene Met72Thr polymorphism is associated with increased risk of wet age-related macular degeneration Am J Ophthalmol 145 4 2008 716 721
    • (2008) Am J Ophthalmol , vol.145 , Issue.4 , pp. 716-721
    • Lin, J.M.1    Wan, L.2    Tsai, Y.Y.3
  • 239
    • 79960025357 scopus 로고    scopus 로고
    • Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy
    • I. Nakata, K. Yamashiro, and R. Yamada Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy Ophthalmology 118 7 2011 1408 1415
    • (2011) Ophthalmology , vol.118 , Issue.7 , pp. 1408-1415
    • Nakata, I.1    Yamashiro, K.2    Yamada, R.3
  • 240
    • 66249126501 scopus 로고    scopus 로고
    • Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss
    • P.J. Francis, S.C. Hamon, J. Ott, R.G. Weleber, and M.L. Klein Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss J Med Genet 46 5 2009 300 307
    • (2009) J Med Genet , vol.46 , Issue.5 , pp. 300-307
    • Francis, P.J.1    Hamon, S.C.2    Ott, J.3    Weleber, R.G.4    Klein, M.L.5
  • 241
    • 33749000285 scopus 로고    scopus 로고
    • VEGF polymorphisms are associated with neovascular age-related macular degeneration
    • A.J. Churchill, J.G. Carter, and H.C. Lovell VEGF polymorphisms are associated with neovascular age-related macular degeneration Hum Mol Genet 15 19 2006 2955 2961
    • (2006) Hum Mol Genet , vol.15 , Issue.19 , pp. 2955-2961
    • Churchill, A.J.1    Carter, J.G.2    Lovell, H.C.3
  • 242
    • 34250312442 scopus 로고    scopus 로고
    • Biochemical alterations in the retinas of very low-density lipoprotein receptor knockout mice: An animal model of retinal angiomatous proliferation
    • C. Li, Z. Huang, and R. Kingsley Biochemical alterations in the retinas of very low-density lipoprotein receptor knockout mice: an animal model of retinal angiomatous proliferation Arch Ophthalmol 125 6 2007 795 803
    • (2007) Arch Ophthalmol , vol.125 , Issue.6 , pp. 795-803
    • Li, C.1    Huang, Z.2    Kingsley, R.3
  • 243
    • 67650802500 scopus 로고    scopus 로고
    • Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress
    • M.I. Dorrell, E. Aguilar, and R. Jacobson Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization- associated oxidative stress J Clin Invest 119 3 2009 611 623
    • (2009) J Clin Invest , vol.119 , Issue.3 , pp. 611-623
    • Dorrell, M.I.1    Aguilar, E.2    Jacobson, R.3
  • 244
    • 36348999343 scopus 로고    scopus 로고
    • Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization
    • Y. Chen, Y. Hu, K. Lu, J.G. Flannery, and J.X. Ma Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization J Biol Chem 282 47 2007 34420 34428
    • (2007) J Biol Chem , vol.282 , Issue.47 , pp. 34420-34428
    • Chen, Y.1    Hu, Y.2    Lu, K.3    Flannery, J.G.4    Ma, J.X.5
  • 245
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulators of the tumor microenvironment
    • K. Kessenbrock, V. Plaks, and Z. Werb Matrix metalloproteinases: regulators of the tumor microenvironment Cell 141 1 2010 52 67
    • (2010) Cell , vol.141 , Issue.1 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 246
    • 1542619261 scopus 로고    scopus 로고
    • Antioxidant role of glutathione S-transferases: Protection against oxidant toxicity and regulation of stress-mediated apoptosis
    • R. Sharma, Y. Yang, A. Sharma, S. Awasthi, and Y.C. Awasthi Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis Antioxid Redox Signal 6 2 2004 289 300
    • (2004) Antioxid Redox Signal , vol.6 , Issue.2 , pp. 289-300
    • Sharma, R.1    Yang, Y.2    Sharma, A.3    Awasthi, S.4    Awasthi, Y.C.5
  • 247
    • 67649840689 scopus 로고    scopus 로고
    • Regulation of superoxide dismutase genes: Implications in disease
    • L. Miao, and D.K. St Clair Regulation of superoxide dismutase genes: implications in disease Free Radic Biol Med 47 4 2009 344 356
    • (2009) Free Radic Biol Med , vol.47 , Issue.4 , pp. 344-356
    • Miao, L.1    St Clair, D.K.2
  • 248
    • 0034533059 scopus 로고    scopus 로고
    • Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration
    • K. Kimura, Y. Isashiki, S. Sonoda, T. Kakiuchi-Matsumoto, and N. Ohba Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration Am J Ophthalmol 130 6 2000 769 773
    • (2000) Am J Ophthalmol , vol.130 , Issue.6 , pp. 769-773
    • Kimura, K.1    Isashiki, Y.2    Sonoda, S.3    Kakiuchi-Matsumoto, T.4    Ohba, N.5
  • 249
    • 35348944706 scopus 로고    scopus 로고
    • Iron homeostasis and toxicity in retinal degeneration
    • X. He, P. Hahn, and J. Iacovelli Iron homeostasis and toxicity in retinal degeneration Prog Retin Eye Res 26 6 2007 649 673
    • (2007) Prog Retin Eye Res , vol.26 , Issue.6 , pp. 649-673
    • He, X.1    Hahn, P.2    Iacovelli, J.3
  • 250
    • 79953721704 scopus 로고    scopus 로고
    • The A Allele of the -576G>A polymorphism of the transferrin gene is associated with the increased risk of age-related macular degeneration in smokers
    • D. Wysokinski, J. Szaflik, and A. Sklodowska The A Allele of the -576G>A polymorphism of the transferrin gene is associated with the increased risk of age-related macular degeneration in smokers Tohoku J Exp Med 223 4 2011 253 261
    • (2011) Tohoku J Exp Med , vol.223 , Issue.4 , pp. 253-261
    • Wysokinski, D.1    Szaflik, J.2    Sklodowska, A.3
  • 251
    • 85027939027 scopus 로고    scopus 로고
    • Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks
    • A.M. Newman, N.B. Gallo, and L.S. Hancox Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks Genome Med 4 2 2012 16
    • (2012) Genome Med , vol.4 , Issue.2 , pp. 16
    • Newman, A.M.1    Gallo, N.B.2    Hancox, L.S.3
  • 252
    • 84859336075 scopus 로고    scopus 로고
    • Differential gene expression in eyecup and retina of a mouse model of Stargardt-like macular dystrophy (STGD3)
    • S. Kuny, F. Gaillard, and Y. Sauve Differential gene expression in eyecup and retina of a mouse model of Stargardt-like macular dystrophy (STGD3) Invest Ophthalmol Vis Sci 53 2 2012 664 675
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.2 , pp. 664-675
    • Kuny, S.1    Gaillard, F.2    Sauve, Y.3
  • 253
    • 33846113273 scopus 로고    scopus 로고
    • Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration
    • M.M. DeAngelis, F. Ji, and I.K. Kim Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration Arch Ophthalmol 125 1 2007 49 54
    • (2007) Arch Ophthalmol , vol.125 , Issue.1 , pp. 49-54
    • Deangelis, M.M.1    Ji, F.2    Kim, I.K.3
  • 254
    • 79958846532 scopus 로고    scopus 로고
    • Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics
    • M. Feehan, J. Hartman, and R. Durante Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics BMC Med Genet 12 2011 83
    • (2011) BMC Med Genet , vol.12 , pp. 83
    • Feehan, M.1    Hartman, J.2    Durante, R.3
  • 255
    • 65549129157 scopus 로고    scopus 로고
    • Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
    • J.M. Seddon, R. Reynolds, J. Maller, J.A. Fagerness, M.J. Daly, and B. Rosner Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables Invest Ophthalmol Vis Sci 50 5 2009 2044 2053
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.5 , pp. 2044-2053
    • Seddon, J.M.1    Reynolds, R.2    Maller, J.3    Fagerness, J.A.4    Daly, M.J.5    Rosner, B.6
  • 256
    • 80052214839 scopus 로고    scopus 로고
    • Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors
    • J.M. Seddon, R. Reynolds, Y. Yu, M.J. Daly, and B. Rosner Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors Ophthalmology 118 11 2011 2203 2211
    • (2011) Ophthalmology , vol.118 , Issue.11 , pp. 2203-2211
    • Seddon, J.M.1    Reynolds, R.2    Yu, Y.3    Daly, M.J.4    Rosner, B.5
  • 257
    • 76149091926 scopus 로고    scopus 로고
    • A genetic approach to stratification of risk for age-related macular degeneration
    • B. Zanke, S. Hawken, R. Carter, and D. Chow A genetic approach to stratification of risk for age-related macular degeneration Can J Ophthalmol 45 1 2010 22 27
    • (2010) Can J Ophthalmol , vol.45 , Issue.1 , pp. 22-27
    • Zanke, B.1    Hawken, S.2    Carter, R.3    Chow, D.4
  • 258
    • 79551546627 scopus 로고    scopus 로고
    • Development of a risk score for geographic atrophy in complications of the age-related macular degeneration prevention trial
    • G.S. Ying, and M.G. Maguire Development of a risk score for geographic atrophy in complications of the age-related macular degeneration prevention trial Ophthalmology 118 2 2011 332 338
    • (2011) Ophthalmology , vol.118 , Issue.2 , pp. 332-338
    • Ying, G.S.1    Maguire, M.G.2
  • 259
    • 80051710075 scopus 로고    scopus 로고
    • Update on the role of genetics in the onset of age-related macular degeneration
    • P.J. Francis, and M.L. Klein Update on the role of genetics in the onset of age-related macular degeneration Clin Ophthalmol 5 2011 1127 1133
    • (2011) Clin Ophthalmol , vol.5 , pp. 1127-1133
    • Francis, P.J.1    Klein, M.L.2
  • 260
    • 36549016602 scopus 로고    scopus 로고
    • Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab
    • M.A. Brantley Jr., A.M. Fang, J.M. King, A. Tewari, S.M. Kymes, and A. Shiels Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab Ophthalmology 114 12 2007 2168 2173
    • (2007) Ophthalmology , vol.114 , Issue.12 , pp. 2168-2173
    • Brantley Jr., M.A.1    Fang, A.M.2    King, J.M.3    Tewari, A.4    Kymes, S.M.5    Shiels, A.6
  • 261
    • 66149089631 scopus 로고    scopus 로고
    • Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab
    • A.Y. Lee, A.K. Raya, S.M. Kymes, A. Shiels, and M.A. Brantley Jr. Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab Br J Ophthalmol 93 5 2009 610 613
    • (2009) Br J Ophthalmol , vol.93 , Issue.5 , pp. 610-613
    • Lee, A.Y.1    Raya, A.K.2    Kymes, S.M.3    Shiels, A.4    Brantley Jr., M.A.5
  • 262
    • 44349192752 scopus 로고    scopus 로고
    • CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
    • M.L. Klein, P.J. Francis, and B. Rosner CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration Ophthalmology 115 6 2008 1019 1025
    • (2008) Ophthalmology , vol.115 , Issue.6 , pp. 1019-1025
    • Klein, M.L.1    Francis, P.J.2    Rosner, B.3
  • 263
    • 38449100345 scopus 로고    scopus 로고
    • Predictive role of coagulation-balance gene polymorphisms in the efficacy of photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to age-related macular degeneration
    • F. Parmeggiani, C. Costagliola, and D. Gemmati Predictive role of coagulation-balance gene polymorphisms in the efficacy of photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to age-related macular degeneration Pharmacogenet Genomics 17 12 2007 1039 1046
    • (2007) Pharmacogenet Genomics , vol.17 , Issue.12 , pp. 1039-1046
    • Parmeggiani, F.1    Costagliola, C.2    Gemmati, D.3
  • 264
    • 48249135691 scopus 로고    scopus 로고
    • Coagulation gene predictors of photodynamic therapy for occult choroidal neovascularization in age-related macular degeneration
    • F. Parmeggiani, C. Costagliola, and D. Gemmati Coagulation gene predictors of photodynamic therapy for occult choroidal neovascularization in age-related macular degeneration Invest Ophthalmol Vis Sci 49 7 2008 3100 3106
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.7 , pp. 3100-3106
    • Parmeggiani, F.1    Costagliola, C.2    Gemmati, D.3
  • 265
    • 62649151512 scopus 로고    scopus 로고
    • Predictive role of C677T MTHFR polymorphism in variable efficacy of photodynamic therapy for neovascular age-related macular degeneration
    • F. Parmeggiani, D. Gemmati, C. Costagliola, A. Sebastiani, and C. Incorvaia Predictive role of C677T MTHFR polymorphism in variable efficacy of photodynamic therapy for neovascular age-related macular degeneration Pharmacogenomics 10 1 2009 81 95
    • (2009) Pharmacogenomics , vol.10 , Issue.1 , pp. 81-95
    • Parmeggiani, F.1    Gemmati, D.2    Costagliola, C.3    Sebastiani, A.4    Incorvaia, C.5
  • 266
    • 84858609076 scopus 로고    scopus 로고
    • Pharmacogenomics in ophthalmology
    • B.S. Shastry Pharmacogenomics in ophthalmology Discov Med 12 63 2011 159 167
    • (2011) Discov Med , vol.12 , Issue.63 , pp. 159-167
    • Shastry, B.S.1
  • 267
    • 84865049405 scopus 로고    scopus 로고
    • Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: A meta-analysis
    • H. Chen, K.D. Yu, and G.Z. Xu Association between variant Y402H in age-related macular degeneration (AMD) susceptibility gene CFH and treatment response of AMD: a meta-analysis PLoS One 7 8 2012 e42464
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 42464
    • Chen, H.1    Yu, K.D.2    Xu, G.Z.3
  • 268
    • 33847153137 scopus 로고    scopus 로고
    • Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications
    • G.S. Hageman, L.S. Hancox, and A.J. Taiber Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications Ann Med 38 8 2006 592 604
    • (2006) Ann Med , vol.38 , Issue.8 , pp. 592-604
    • Hageman, G.S.1    Hancox, L.S.2    Taiber, A.J.3
  • 269
    • 79960942836 scopus 로고    scopus 로고
    • Copy number variations in candidate genes in neovascular age-related macular degeneration
    • M.M. Liu, E. Agron, and E. Chew Copy number variations in candidate genes in neovascular age-related macular degeneration Invest Ophthalmol Vis Sci 52 6 2011 3129 3135
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.6 , pp. 3129-3135
    • Liu, M.M.1    Agron, E.2    Chew, E.3
  • 270
    • 20444471500 scopus 로고    scopus 로고
    • Association of HLA class i and class II polymorphisms with age-related macular degeneration
    • S.V. Goverdhan, M.W. Howell, and R.F. Mullins Association of HLA class I and class II polymorphisms with age-related macular degeneration Invest Ophthalmol Vis Sci 46 5 2005 1726 1734
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.5 , pp. 1726-1734
    • Goverdhan, S.V.1    Howell, M.W.2    Mullins, R.F.3
  • 271
    • 0031719049 scopus 로고    scopus 로고
    • Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes
    • B. Steen, S. Sejersen, L. Berglin, S. Seregard, and A. Kvanta Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes Invest Ophthalmol Vis Sci 39 11 1998 2194 2200
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.11 , pp. 2194-2200
    • Steen, B.1    Sejersen, S.2    Berglin, L.3    Seregard, S.4    Kvanta, A.5
  • 272
    • 18344367084 scopus 로고    scopus 로고
    • MMP-9 microsatellite polymorphism and susceptibility to exudative form of age-related macular degeneration
    • N. Fiotti, M. Pedio, and M. Battaglia Parodi MMP-9 microsatellite polymorphism and susceptibility to exudative form of age-related macular degeneration Genet Med 7 4 2005 272 277
    • (2005) Genet Med , vol.7 , Issue.4 , pp. 272-277
    • Fiotti, N.1    Pedio, M.2    Battaglia Parodi, M.3
  • 273
    • 45449091963 scopus 로고    scopus 로고
    • Plasma levels of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) in age-related macular degeneration
    • K.Y. Chau, S. Sivaprasad, N. Patel, T.A. Donaldson, P.J. Luthert, and N.V. Chong Plasma levels of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) in age-related macular degeneration Eye (Lond) 22 6 2008 855 859
    • (2008) Eye (Lond) , vol.22 , Issue.6 , pp. 855-859
    • Chau, K.Y.1    Sivaprasad, S.2    Patel, N.3    Donaldson, T.A.4    Luthert, P.J.5    Chong, N.V.6
  • 274
    • 78650796012 scopus 로고    scopus 로고
    • Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study
    • E. Ryu, B.L. Fridley, N. Tosakulwong, K.R. Bailey, and A.O. Edwards Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study Mol Vis 16 2010 2811 2821
    • (2010) Mol Vis , vol.16 , pp. 2811-2821
    • Ryu, E.1    Fridley, B.L.2    Tosakulwong, N.3    Bailey, K.R.4    Edwards, A.O.5
  • 275
    • 78149486832 scopus 로고    scopus 로고
    • LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis
    • Y. Tong, J. Liao, Y. Zhang, J. Zhou, H. Zhang, and M. Mao LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis Mol Vis 16 2010 1958 1981
    • (2010) Mol Vis , vol.16 , pp. 1958-1981
    • Tong, Y.1    Liao, J.2    Zhang, Y.3    Zhou, J.4    Zhang, H.5    Mao, M.6
  • 276
    • 11144258543 scopus 로고    scopus 로고
    • Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
    • J.W. Crabb, M. Miyagi, and X. Gu Drusen proteome analysis: an approach to the etiology of age-related macular degeneration Proc Natl Acad Sci U S A 99 23 2002 14682 14687
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.23 , pp. 14682-14687
    • Crabb, J.W.1    Miyagi, M.2    Gu, X.3
  • 277
    • 3242719404 scopus 로고    scopus 로고
    • Missense variations in the fibulin 5 gene and age-related macular degeneration
    • E.M. Stone, T.A. Braun, and S.R. Russell Missense variations in the fibulin 5 gene and age-related macular degeneration N Engl J Med 351 4 2004 346 353
    • (2004) N Engl J Med , vol.351 , Issue.4 , pp. 346-353
    • Stone, E.M.1    Braun, T.A.2    Russell, S.R.3
  • 278
    • 0026439413 scopus 로고
    • Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group Arch Ophthalmol 110 12 1992 1701 1708
    • (1992) Arch Ophthalmol , vol.110 , Issue.12 , pp. 1701-1708
  • 279
    • 0027397668 scopus 로고
    • Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group Arch Ophthalmol 111 1 1993 104 109
    • (1993) Arch Ophthalmol , vol.111 , Issue.1 , pp. 104-109
  • 280
    • 0027946498 scopus 로고
    • Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group
    • J.M. Seddon, U.A. Ajani, and R.D. Sperduto Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group JAMA 272 18 1994 1413 1420
    • (1994) JAMA , vol.272 , Issue.18 , pp. 1413-1420
    • Seddon, J.M.1    Ajani, U.A.2    Sperduto, R.D.3
  • 281
    • 0023813198 scopus 로고
    • Factors associated with age-related macular degeneration. An analysis of data from the first National Health and Nutrition Examination Survey
    • J. Goldberg, G. Flowerdew, E. Smith, J.A. Brody, and M.O. Tso Factors associated with age-related macular degeneration. An analysis of data from the first National Health and Nutrition Examination Survey Am J Epidemiol 128 4 1988 700 710
    • (1988) Am J Epidemiol , vol.128 , Issue.4 , pp. 700-710
    • Goldberg, J.1    Flowerdew, G.2    Smith, E.3    Brody, J.A.4    Tso, M.O.5
  • 282
    • 0032527738 scopus 로고    scopus 로고
    • Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculopathy in the Beaver Dam Eye Study
    • G.M. VandenLangenberg, J.A. Mares-Perlman, R. Klein, B.E. Klein, W.E. Brady, and M. Palta Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculopathy in the Beaver Dam Eye Study Am J Epidemiol 148 2 1998 204 214
    • (1998) Am J Epidemiol , vol.148 , Issue.2 , pp. 204-214
    • Vandenlangenberg, G.M.1    Mares-Perlman, J.A.2    Klein, R.3    Klein, B.E.4    Brady, W.E.5    Palta, M.6
  • 283
    • 0033436360 scopus 로고    scopus 로고
    • The Age-Related Eye Disease Study (AREDS): Design implications. AREDS report no. 1
    • Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group The Age-Related Eye Disease Study (AREDS): design implications. AREDS report no. 1 Control Clin Trials 20 6 1999 573 600
    • (1999) Control Clin Trials , vol.20 , Issue.6 , pp. 573-600
  • 284
    • 0034109890 scopus 로고    scopus 로고
    • The Age-Related Eye Disease Study: A clinical trial of zinc and antioxidants - Age-Related Eye Disease Study report no. 2
    • Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group The Age-Related Eye Disease Study: a clinical trial of zinc and antioxidants - Age-Related Eye Disease Study report no. 2 J Nutr 130 5S Suppl 2000 1516S 1519S
    • (2000) J Nutr , vol.130 , Issue.5 SUPPL.
  • 285
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
    • Age-Related Eye Disease Study Research Group
    • Age-Related Eye Disease Study Research Group A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8 Arch Ophthalmol 119 10 2001 1417 1436
    • (2001) Arch Ophthalmol , vol.119 , Issue.10 , pp. 1417-1436
  • 286
    • 0034791751 scopus 로고    scopus 로고
    • Antioxidants, zinc, and age-related macular degeneration: Results and recommendations
    • L.M. Jampol Antioxidants, zinc, and age-related macular degeneration: results and recommendations Arch Ophthalmol 119 10 2001 1533 1534
    • (2001) Arch Ophthalmol , vol.119 , Issue.10 , pp. 1533-1534
    • Jampol, L.M.1
  • 287
    • 0036295596 scopus 로고    scopus 로고
    • AREDS investigators distort findings
    • D. Seigel AREDS investigators distort findings Arch Ophthalmol 120 1 2002 100 101
    • (2002) Arch Ophthalmol , vol.120 , Issue.1 , pp. 100-101
    • Seigel, D.1
  • 288
    • 0036315248 scopus 로고    scopus 로고
    • Age-related eye disease study caveats
    • author reply 997-999
    • J. Ambati, and B.K. Ambati Age-related eye disease study caveats Arch Ophthalmol 120 7 2002 997 author reply 997-999
    • (2002) Arch Ophthalmol , vol.120 , Issue.7 , pp. 997
    • Ambati, J.1    Ambati, B.K.2
  • 289
    • 0036315248 scopus 로고    scopus 로고
    • Age-related eye disease study caveats [author reply]
    • author reply 997-999
    • F. Ferris III, A.S. Lindblad, and R.C. Milton Age-related eye disease study caveats [author reply] Arch Ophthalmol 120 7 2002 997 author reply 997-999
    • (2002) Arch Ophthalmol , vol.120 , Issue.7 , pp. 997
    • Ferris Iii, F.1    Lindblad, A.S.2    Milton, R.C.3
  • 290
    • 29544441148 scopus 로고    scopus 로고
    • Dietary intake of antioxidants and risk of age-related macular degeneration
    • R. van Leeuwen, S. Boekhoorn, and J.R. Vingerling Dietary intake of antioxidants and risk of age-related macular degeneration JAMA 294 24 2005 3101 3107
    • (2005) JAMA , vol.294 , Issue.24 , pp. 3101-3107
    • Van Leeuwen, R.1    Boekhoorn, S.2    Vingerling, J.R.3
  • 291
    • 79958726856 scopus 로고    scopus 로고
    • Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and omega-3 fatty acids: The Rotterdam study
    • L. Ho, R. van Leeuwen, and J.C. Witteman Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and omega-3 fatty acids: the Rotterdam study Arch Ophthalmol 129 6 2011 758 766
    • (2011) Arch Ophthalmol , vol.129 , Issue.6 , pp. 758-766
    • Ho, L.1    Van Leeuwen, R.2    Witteman, J.C.3
  • 292
    • 27744508407 scopus 로고    scopus 로고
    • The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS report no. 17
    • M.D. Davis, R.E. Gangnon, and L.Y. Lee The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS report no. 17 Arch Ophthalmol 123 11 2005 1484 1498
    • (2005) Arch Ophthalmol , vol.123 , Issue.11 , pp. 1484-1498
    • Davis, M.D.1    Gangnon, R.E.2    Lee, L.Y.3
  • 293
    • 27744516278 scopus 로고    scopus 로고
    • A simplified severity scale for age-related macular degeneration: AREDS report no. 18
    • F.L. Ferris, M.D. Davis, and T.E. Clemons A simplified severity scale for age-related macular degeneration: AREDS report no. 18 Arch Ophthalmol 123 11 2005 1570 1574
    • (2005) Arch Ophthalmol , vol.123 , Issue.11 , pp. 1570-1574
    • Ferris, F.L.1    Davis, M.D.2    Clemons, T.E.3
  • 294
    • 33745023856 scopus 로고    scopus 로고
    • Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration
    • J.R. Evans Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration Cochrane Database Syst Rev 2 2006 CD000254
    • (2006) Cochrane Database Syst Rev , Issue.2 , pp. 000254
    • Evans, J.R.1
  • 295
    • 45449118333 scopus 로고    scopus 로고
    • Antioxidant supplements to prevent or slow down the progression of AMD: A systematic review and meta-analysis
    • J. Evans Antioxidant supplements to prevent or slow down the progression of AMD: a systematic review and meta-analysis Eye (Lond) 22 6 2008 751 760
    • (2008) Eye (Lond) , vol.22 , Issue.6 , pp. 751-760
    • Evans, J.1
  • 296
    • 35348966298 scopus 로고    scopus 로고
    • Dietary antioxidants and primary prevention of age related macular degeneration: Systematic review and meta-analysis
    • E.W. Chong, T.Y. Wong, A.J. Kreis, J.A. Simpson, and R.H. Guymer Dietary antioxidants and primary prevention of age related macular degeneration: systematic review and meta-analysis BMJ 335 7623 2007 755
    • (2007) BMJ , vol.335 , Issue.7623 , pp. 755
    • Chong, E.W.1    Wong, T.Y.2    Kreis, A.J.3    Simpson, J.A.4    Guymer, R.H.5
  • 297
    • 44949238599 scopus 로고    scopus 로고
    • Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration
    • J.R. Evans, and K. Henshaw Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration Cochrane Database Syst Rev 1 2008 CD000253
    • (2008) Cochrane Database Syst Rev , Issue.1 , pp. 000253
    • Evans, J.R.1    Henshaw, K.2
  • 298
    • 44949238599 scopus 로고    scopus 로고
    • Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration
    • J.R. Evans, and J.G. Lawrenson Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration Cochrane Database Syst Rev 6 2012 CD000253
    • (2012) Cochrane Database Syst Rev , vol.6 , pp. 000253
    • Evans, J.R.1    Lawrenson, J.G.2
  • 299
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • J.L. Haines, M.A. Hauser, and S. Schmidt Complement factor H variant increases the risk of age-related macular degeneration Science 308 5720 2005 419 421
    • (2005) Science , vol.308 , Issue.5720 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3
  • 301
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • R.J. Klein, C. Zeiss, and E.Y. Chew Complement factor H polymorphism in age-related macular degeneration Science 308 5720 2005 385 389
    • (2005) Science , vol.308 , Issue.5720 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 302
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • G.S. Hageman, D.H. Anderson, and L.V. Johnson A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc Natl Acad Sci U S A 102 20 2005 7227 7232
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.20 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3
  • 303
    • 20544471911 scopus 로고    scopus 로고
    • Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration
    • S. Zareparsi, K.E. Branham, and M. Li Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration Am J Hum Genet 77 1 2005 149 153
    • (2005) Am J Hum Genet , vol.77 , Issue.1 , pp. 149-153
    • Zareparsi, S.1    Branham, K.E.2    Li, M.3
  • 304
    • 44349192752 scopus 로고    scopus 로고
    • CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
    • M.L. Klein, P.J. Francis, and B. Rosner CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration Ophthalmology 115 6 2008 1019 1025
    • (2008) Ophthalmology , vol.115 , Issue.6 , pp. 1019-1025
    • Klein, M.L.1    Francis, P.J.2    Rosner, B.3
  • 305
    • 33846013969 scopus 로고    scopus 로고
    • High dose zinc increases hospital admissions due to genitourinary complications
    • A.R. Johnson, A. Munoz, J.L. Gottlieb, and D.F. Jarrard High dose zinc increases hospital admissions due to genitourinary complications J Urol 177 2 2007 639 643
    • (2007) J Urol , vol.177 , Issue.2 , pp. 639-643
    • Johnson, A.R.1    Munoz, A.2    Gottlieb, J.L.3    Jarrard, D.F.4
  • 306
    • 58149389262 scopus 로고    scopus 로고
    • Vitamin A and retinol intakes and the risk of fractures among participants of the Women's Health Initiative Observational Study
    • G. Caire-Juvera, C. Ritenbaugh, J. Wactawski-Wende, L.G. Snetselaar, and Z. Chen Vitamin A and retinol intakes and the risk of fractures among participants of the Women's Health Initiative Observational Study Am J Clin Nutr 89 1 2009 323 330
    • (2009) Am J Clin Nutr , vol.89 , Issue.1 , pp. 323-330
    • Caire-Juvera, G.1    Ritenbaugh, C.2    Wactawski-Wende, J.3    Snetselaar, L.G.4    Chen, Z.5
  • 307
    • 66349125617 scopus 로고    scopus 로고
    • Protective effect of total carotenoid and lycopene intake on the risk of hip fracture: A 17-year follow-up from the Framingham Osteoporosis Study
    • S. Sahni, M.T. Hannan, J. Blumberg, L.A. Cupples, D.P. Kiel, and K.L. Tucker Protective effect of total carotenoid and lycopene intake on the risk of hip fracture: a 17-year follow-up from the Framingham Osteoporosis Study J Bone Miner Res 24 6 2009 1086 1094
    • (2009) J Bone Miner Res , vol.24 , Issue.6 , pp. 1086-1094
    • Sahni, S.1    Hannan, M.T.2    Blumberg, J.3    Cupples, L.A.4    Kiel, D.P.5    Tucker, K.L.6
  • 308
    • 80053954605 scopus 로고    scopus 로고
    • Vitamin e and the risk of prostate cancer: The Selenium and Vitamin e Cancer Prevention Trial (SELECT)
    • E.A. Klein, I.M. Thompson Jr., and C.M. Tangen Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT) JAMA 306 14 2011 1549 1556
    • (2011) JAMA , vol.306 , Issue.14 , pp. 1549-1556
    • Klein, E.A.1    Thompson Jr., I.M.2    Tangen, C.M.3
  • 309
    • 58149375890 scopus 로고    scopus 로고
    • Vitamins e and C in the prevention of prostate and total cancer in men: The Physicians' Health Study II randomized controlled trial
    • J.M. Gaziano, R.J. Glynn, and W.G. Christen Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial JAMA 301 1 2009 52 62
    • (2009) JAMA , vol.301 , Issue.1 , pp. 52-62
    • Gaziano, J.M.1    Glynn, R.J.2    Christen, W.G.3
  • 310
    • 0028818968 scopus 로고
    • Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study
    • D. Albanes, O.P. Heinonen, and J.K. Huttunen Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study Am J Clin Nutr 62 6 Suppl 1995 1427S 1430S
    • (1995) Am J Clin Nutr , vol.62 , Issue.6 SUPPL.
    • Albanes, D.1    Heinonen, O.P.2    Huttunen, J.K.3
  • 312
    • 33747185607 scopus 로고    scopus 로고
    • Associations between intermediate age-related macular degeneration and lutein and zeaxanthin in the Carotenoids in Age-related Eye Disease Study (CAREDS): Ancillary study of the Women's Health Initiative
    • S.M. Moeller, N. Parekh, and L. Tinker Associations between intermediate age-related macular degeneration and lutein and zeaxanthin in the Carotenoids in Age-related Eye Disease Study (CAREDS): ancillary study of the Women's Health Initiative Arch Ophthalmol 124 8 2006 1151 1162
    • (2006) Arch Ophthalmol , vol.124 , Issue.8 , pp. 1151-1162
    • Moeller, S.M.1    Parekh, N.2    Tinker, L.3
  • 313
    • 38749097003 scopus 로고    scopus 로고
    • Dietary antioxidants and the long-term incidence of age-related macular degeneration: The Blue Mountains Eye Study
    • J.S. Tan, J.J. Wang, V. Flood, E. Rochtchina, W. Smith, and P. Mitchell Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study Ophthalmology 115 2 2008 334 341
    • (2008) Ophthalmology , vol.115 , Issue.2 , pp. 334-341
    • Tan, J.S.1    Wang, J.J.2    Flood, V.3    Rochtchina, E.4    Smith, W.5    Mitchell, P.6
  • 314
    • 34548650913 scopus 로고    scopus 로고
    • The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS report no. 22
    • J.P. SanGiovanni, E.Y. Chew, and T.E. Clemons The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS report no. 22 Arch Ophthalmol 125 9 2007 1225 1232
    • (2007) Arch Ophthalmol , vol.125 , Issue.9 , pp. 1225-1232
    • Sangiovanni, J.P.1    Chew, E.Y.2    Clemons, T.E.3
  • 315
    • 84868196171 scopus 로고    scopus 로고
    • The Age-Related Eye Disease Study 2 (AREDS2): Study design and baseline characteristics (AREDS2 report number 1)
    • E.Y. Chew, T. Clemons, and J.P. Sangiovanni The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1) Ophthalmology 119 11 2012 2282 2289
    • (2012) Ophthalmology , vol.119 , Issue.11 , pp. 2282-2289
    • Chew, E.Y.1    Clemons, T.2    Sangiovanni, J.P.3
  • 316
    • 77951298125 scopus 로고    scopus 로고
    • Nutritional supplements for age-related macular degeneration
    • N. Krishnadev, A.D. Meleth, and E.Y. Chew Nutritional supplements for age-related macular degeneration Curr Opin Ophthalmol 21 3 2010 184 189
    • (2010) Curr Opin Ophthalmol , vol.21 , Issue.3 , pp. 184-189
    • Krishnadev, N.1    Meleth, A.D.2    Chew, E.Y.3
  • 317
    • 79956214436 scopus 로고    scopus 로고
    • Fatty acids and retinopathy
    • E.Y. Chew Fatty acids and retinopathy N Engl J Med 364 20 2011 1970 1971
    • (2011) N Engl J Med , vol.364 , Issue.20 , pp. 1970-1971
    • Chew, E.Y.1
  • 318
    • 84871181392 scopus 로고    scopus 로고
    • National Eye Institute (NEI) http://clinicaltrials.gov/ct2/show/ NCT00345176. Accessed October 15
    • National Eye Institute (NEI). Age-Related Eye Disease Study 2 (AREDS2). In: ClinicalTrials.gov. Available at: http://clinicaltrials.gov/ct2/show/ NCT00345176. Accessed October 15, 2012.
    • (2012) Age-Related Eye Disease Study 2 (AREDS2)
  • 319
    • 34447119437 scopus 로고    scopus 로고
    • Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis
    • K.M. Connor, J.P. SanGiovanni, and C. Lofqvist Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis Nat Med 13 7 2007 868 873
    • (2007) Nat Med , vol.13 , Issue.7 , pp. 868-873
    • Connor, K.M.1    Sangiovanni, J.P.2    Lofqvist, C.3
  • 320
    • 77956230472 scopus 로고    scopus 로고
    • Short communication: PPAR gamma mediates a direct antiangiogenic effect of omega 3-PUFAs in proliferative retinopathy
    • A. Stahl, P. Sapieha, and K.M. Connor Short communication: PPAR gamma mediates a direct antiangiogenic effect of omega 3-PUFAs in proliferative retinopathy Circ Res 107 4 2010 495 500
    • (2010) Circ Res , vol.107 , Issue.4 , pp. 495-500
    • Stahl, A.1    Sapieha, P.2    Connor, K.M.3
  • 321
    • 79851475199 scopus 로고    scopus 로고
    • 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of omega-3 polyunsaturated fatty acids
    • P. Sapieha, A. Stahl, and J. Chen 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of omega-3 polyunsaturated fatty acids Sci Transl Med 3 69 2011 69ra12
    • (2011) Sci Transl Med , vol.3 , Issue.69
    • Sapieha, P.1    Stahl, A.2    Chen, J.3
  • 322
    • 84855299970 scopus 로고    scopus 로고
    • Associations between aspirin use and aging macula disorder: The European Eye Study
    • P.T. de Jong, U. Chakravarthy, and M. Rahu Associations between aspirin use and aging macula disorder: the European Eye Study Ophthalmology 119 1 2012 112 118
    • (2012) Ophthalmology , vol.119 , Issue.1 , pp. 112-118
    • De Jong, P.T.1    Chakravarthy, U.2    Rahu, M.3
  • 323
    • 0034908261 scopus 로고    scopus 로고
    • Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians
    • W.G. Christen, R.J. Glynn, and U.A. Ajani Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians Arch Ophthalmol 119 8 2001 1143 1149
    • (2001) Arch Ophthalmol , vol.119 , Issue.8 , pp. 1143-1149
    • Christen, W.G.1    Glynn, R.J.2    Ajani, U.A.3
  • 324
    • 70649099133 scopus 로고    scopus 로고
    • Low-dose aspirin and medical record-confirmed age-related macular degeneration in a randomized trial of women
    • W.G. Christen, R.J. Glynn, E.Y. Chew, and J.E. Buring Low-dose aspirin and medical record-confirmed age-related macular degeneration in a randomized trial of women Ophthalmology 116 12 2009 2386 2392
    • (2009) Ophthalmology , vol.116 , Issue.12 , pp. 2386-2392
    • Christen, W.G.1    Glynn, R.J.2    Chew, E.Y.3    Buring, J.E.4
  • 325
    • 54949156790 scopus 로고    scopus 로고
    • Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? the Age-Related Maculopathy Statin Study (ARMSS)
    • R.H. Guymer, P.N. Dimitrov, and M. Varsamidis Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The Age-Related Maculopathy Statin Study (ARMSS) Clin Interv Aging 3 3 2008 581 593
    • (2008) Clin Interv Aging , vol.3 , Issue.3 , pp. 581-593
    • Guymer, R.H.1    Dimitrov, P.N.2    Varsamidis, M.3
  • 327
    • 67649643741 scopus 로고    scopus 로고
    • Statins do not decrease the risk for wet age-related macular degeneration
    • N. Kaiserman, S. Vinker, and I. Kaiserman Statins do not decrease the risk for wet age-related macular degeneration Curr Eye Res 34 4 2009 304 310
    • (2009) Curr Eye Res , vol.34 , Issue.4 , pp. 304-310
    • Kaiserman, N.1    Vinker, S.2    Kaiserman, I.3
  • 328
    • 77952672357 scopus 로고    scopus 로고
    • Recent statin use and 1-year incidence of exudative age-related macular degeneration
    • D.S. Fong, and R. Contreras Recent statin use and 1-year incidence of exudative age-related macular degeneration Am J Ophthalmol 149 6 2010 955 958.e1
    • (2010) Am J Ophthalmol , vol.149 , Issue.6
    • Fong, D.S.1    Contreras, R.2
  • 329
    • 14644394842 scopus 로고    scopus 로고
    • The use of cholesterol-lowering medications and age-related macular degeneration
    • G. McGwin Jr., A. Xie, and C. Owsley The use of cholesterol-lowering medications and age-related macular degeneration Ophthalmology 112 3 2005 488 494
    • (2005) Ophthalmology , vol.112 , Issue.3 , pp. 488-494
    • Mcgwin Jr., G.1    Xie, A.2    Owsley, C.3
  • 330
    • 38949137323 scopus 로고    scopus 로고
    • Use of statins and angiotensin converting enzyme inhibitors (ACE-Is) and the risk of age-related macular degeneration: Nested case-control study
    • M. Etminan, J.M. Brophy, and D. Maberley Use of statins and angiotensin converting enzyme inhibitors (ACE-Is) and the risk of age-related macular degeneration: nested case-control study Curr Drug Saf 3 1 2008 24 26
    • (2008) Curr Drug Saf , vol.3 , Issue.1 , pp. 24-26
    • Etminan, M.1    Brophy, J.M.2    Maberley, D.3
  • 331
    • 70649100017 scopus 로고    scopus 로고
    • Statin use and the incidence of advanced age-related macular degeneration in the Complications of Age-Related Macular Degeneration Prevention Trial
    • M.G. Maguire, G.S. Ying, C.A. McCannel, C. Liu, and Y. Dai Statin use and the incidence of advanced age-related macular degeneration in the Complications of Age-Related Macular Degeneration Prevention Trial Ophthalmology 116 12 2009 2381 2385
    • (2009) Ophthalmology , vol.116 , Issue.12 , pp. 2381-2385
    • Maguire, M.G.1    Ying, G.S.2    McCannel, C.A.3    Liu, C.4    Dai, Y.5
  • 332
    • 33847072001 scopus 로고    scopus 로고
    • Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study
    • R. Klein, Y. Deng, and B.E. Klein Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study Am J Ophthalmol 143 3 2007 473 483
    • (2007) Am J Ophthalmol , vol.143 , Issue.3 , pp. 473-483
    • Klein, R.1    Deng, Y.2    Klein, B.E.3
  • 333
    • 79952685446 scopus 로고    scopus 로고
    • Statin use and the risk of age related macular degeneration in a large health organization in Israel
    • V. Shalev, M. Sror, I. Goldshtein, E. Kokia, and G. Chodick Statin use and the risk of age related macular degeneration in a large health organization in Israel Ophthalmic Epidemiol 18 2 2011 83 90
    • (2011) Ophthalmic Epidemiol , vol.18 , Issue.2 , pp. 83-90
    • Shalev, V.1    Sror, M.2    Goldshtein, I.3    Kokia, E.4    Chodick, G.5
  • 335
    • 0015816276 scopus 로고
    • Drusen and disciform macular detachment and degeneration
    • J.D. Gass Drusen and disciform macular detachment and degeneration Arch Ophthalmol 90 3 1973 206 217
    • (1973) Arch Ophthalmol , vol.90 , Issue.3 , pp. 206-217
    • Gass, J.D.1
  • 336
    • 0018620874 scopus 로고
    • Prophylactic photocoagulation of the fellow eye in exudative senile maculopathy. A preliminary report
    • G.W. Cleasby, A.S. Nakanishi, and J.L. Norris Prophylactic photocoagulation of the fellow eye in exudative senile maculopathy. A preliminary report Mod Probl Ophthalmol 20 1979 141 147
    • (1979) Mod Probl Ophthalmol , vol.20 , pp. 141-147
    • Cleasby, G.W.1    Nakanishi, A.S.2    Norris, J.L.3
  • 337
    • 0028611978 scopus 로고
    • Photocoagulation of drusen-related macular degeneration: A long-term outcome
    • discussion 303-306
    • P.C. Wetzig Photocoagulation of drusen-related macular degeneration: a long-term outcome Trans Am Ophthalmol Soc 92 1994 299 303 discussion 303-306
    • (1994) Trans Am Ophthalmol Soc , vol.92 , pp. 299-303
    • Wetzig, P.C.1
  • 338
    • 0031821170 scopus 로고    scopus 로고
    • Prophylactic laser treatment to fellow eyes of unilateral retinal pigment epithelial tears
    • M. Gross-Jendroska, S.L. Owens, C.J. Flaxel, R.H. Guymer, and A.C. Bird Prophylactic laser treatment to fellow eyes of unilateral retinal pigment epithelial tears Am J Ophthalmol 126 1 1998 77 81
    • (1998) Am J Ophthalmol , vol.126 , Issue.1 , pp. 77-81
    • Gross-Jendroska, M.1    Owens, S.L.2    Flaxel, C.J.3    Guymer, R.H.4    Bird, A.C.5
  • 339
    • 70049083998 scopus 로고    scopus 로고
    • Laser treatment of drusen to prevent progression to advanced age-related macular degeneration
    • M.B. Parodi, G. Virgili, and J.R. Evans Laser treatment of drusen to prevent progression to advanced age-related macular degeneration Cochrane Database Syst Rev 3 2009 CD006537
    • (2009) Cochrane Database Syst Rev , Issue.3 , pp. 006537
    • Parodi, M.B.1    Virgili, G.2    Evans, J.R.3
  • 340
    • 84859508530 scopus 로고    scopus 로고
    • Vectorial release of matrix metalloproteinases (MMPs) from porcine RPE-choroid explants following selective retina therapy (SRT): Towards slowing the macular ageing process
    • F. Treumer, A. Klettner, and J. Baltz Vectorial release of matrix metalloproteinases (MMPs) from porcine RPE-choroid explants following selective retina therapy (SRT): towards slowing the macular ageing process Exp Eye Res 97 1 2012 63 72
    • (2012) Exp Eye Res , vol.97 , Issue.1 , pp. 63-72
    • Treumer, F.1    Klettner, A.2    Baltz, J.3
  • 341
    • 84865163185 scopus 로고    scopus 로고
    • Laser-mediated activation of human retinal pigment epithelial cells and concomitant release of matrix metalloproteinases
    • J.J. Zhang, Y. Sun, A.A. Hussain, and J. Marshall Laser-mediated activation of human retinal pigment epithelial cells and concomitant release of matrix metalloproteinases Invest Ophthalmol Vis Sci 53 6 2012 2928 2937
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.6 , pp. 2928-2937
    • Zhang, J.J.1    Sun, Y.2    Hussain, A.A.3    Marshall, J.4
  • 342
    • 15044338733 scopus 로고    scopus 로고
    • Age-related macular degeneration 1969-2004: A 35-year personal perspective
    • S.L. Fine Age-related macular degeneration 1969-2004: a 35-year personal perspective Am J Ophthalmol 139 3 2005 405 420
    • (2005) Am J Ophthalmol , vol.139 , Issue.3 , pp. 405-420
    • Fine, S.L.1
  • 343
    • 0026409933 scopus 로고
    • Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group Arch Ophthalmol 109 8 1991 1109 1114
    • (1991) Arch Ophthalmol , vol.109 , Issue.8 , pp. 1109-1114
  • 344
    • 0025368325 scopus 로고
    • Krypton laser photocoagulation for neovascular lesions of age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group Krypton laser photocoagulation for neovascular lesions of age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group Arch Ophthalmol 108 6 1990 816 824
    • (1990) Arch Ophthalmol , vol.108 , Issue.6 , pp. 816-824
  • 345
    • 0022534775 scopus 로고
    • Argon laser photocoagulation for neovascular maculopathy. Three-year results from randomized clinical trials. Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group Argon laser photocoagulation for neovascular maculopathy. Three-year results from randomized clinical trials. Macular Photocoagulation Study Group Arch Ophthalmol 104 5 1986 694 701
    • (1986) Arch Ophthalmol , vol.104 , Issue.5 , pp. 694-701
  • 346
    • 0027237206 scopus 로고
    • Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration. Updated findings from two clinical trials. Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group
    • Macular Photocoagulation Study Group Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration. Updated findings from two clinical trials. Macular Photocoagulation Study Group Arch Ophthalmol 111 9 1993 1200 1209
    • (1993) Arch Ophthalmol , vol.111 , Issue.9 , pp. 1200-1209
  • 347
    • 0026085878 scopus 로고
    • Surgical removal of subfoveal neovascularization in the presumed ocular histoplasmosis syndrome
    • M.A. Thomas, and H.J. Kaplan Surgical removal of subfoveal neovascularization in the presumed ocular histoplasmosis syndrome Am J Ophthalmol 111 1 1991 1 7
    • (1991) Am J Ophthalmol , vol.111 , Issue.1 , pp. 1-7
    • Thomas, M.A.1    Kaplan, H.J.2
  • 348
    • 0033778464 scopus 로고    scopus 로고
    • Visual outcome after surgical removal of choroidal neovascularization in pediatric patients
    • A. Uemura, and M.A. Thomas Visual outcome after surgical removal of choroidal neovascularization in pediatric patients Arch Ophthalmol 118 10 2000 1373 1378
    • (2000) Arch Ophthalmol , vol.118 , Issue.10 , pp. 1373-1378
    • Uemura, A.1    Thomas, M.A.2
  • 349
    • 7444227954 scopus 로고    scopus 로고
    • Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: Ophthalmic findings: SST report no. 11
    • B.S. Hawkins, N.M. Bressler, and P.H. Miskala Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: ophthalmic findings: SST report no. 11 Ophthalmology 111 11 2004 1967 1980
    • (2004) Ophthalmology , vol.111 , Issue.11 , pp. 1967-1980
    • Hawkins, B.S.1    Bressler, N.M.2    Miskala, P.H.3
  • 350
    • 0031781192 scopus 로고    scopus 로고
    • Macular translocation
    • R. Machemer Macular translocation Am J Ophthalmol 125 5 1998 698 700
    • (1998) Am J Ophthalmol , vol.125 , Issue.5 , pp. 698-700
    • MacHemer, R.1
  • 351
    • 79955644519 scopus 로고    scopus 로고
    • Sub-macular surgery: Is still an option for age-related macular degeneration?
    • M.R. Romano, X. Valldeperas, P. Vinciguerra, and D. Wong Sub-macular surgery: is still an option for age-related macular degeneration? Curr Drug Targets 12 2 2011 190 198
    • (2011) Curr Drug Targets , vol.12 , Issue.2 , pp. 190-198
    • Romano, M.R.1    Valldeperas, X.2    Vinciguerra, P.3    Wong, D.4
  • 352
    • 70349118692 scopus 로고    scopus 로고
    • Submacular surgery for choroidal neovascularisation secondary to age-related macular degeneration
    • F. Giansanti, C.M. Eandi, and G. Virgili Submacular surgery for choroidal neovascularisation secondary to age-related macular degeneration Cochrane Database Syst Rev 2 2009 CD006931
    • (2009) Cochrane Database Syst Rev , Issue.2 , pp. 006931
    • Giansanti, F.1    Eandi, C.M.2    Virgili, G.3
  • 354
    • 67649208336 scopus 로고    scopus 로고
    • Recurrent choroidal neovascularization after macular translocation surgery with 360-degree peripheral retinectomy
    • C.A. Baer, C.B. Rickman, S. Srivastava, G. Malek, S. Stinnett, and C.A. Toth Recurrent choroidal neovascularization after macular translocation surgery with 360-degree peripheral retinectomy Retina 28 9 2008 1221 1227
    • (2008) Retina , vol.28 , Issue.9 , pp. 1221-1227
    • Baer, C.A.1    Rickman, C.B.2    Srivastava, S.3    Malek, G.4    Stinnett, S.5    Toth, C.A.6
  • 355
    • 7544230169 scopus 로고    scopus 로고
    • The age-related macular degeneration radiotherapy trial (AMDRT): One year results from a pilot study
    • D.M. Marcus, E. Peskin, and M. Maguire The age-related macular degeneration radiotherapy trial (AMDRT): one year results from a pilot study Am J Ophthalmol 138 5 2004 818 828
    • (2004) Am J Ophthalmol , vol.138 , Issue.5 , pp. 818-828
    • Marcus, D.M.1    Peskin, E.2    Maguire, M.3
  • 356
    • 0345863697 scopus 로고    scopus 로고
    • Radiotherapy for recurrent choroidal neovascularisation complicating age related macular degeneration
    • D.M. Marcus, W.C. Sheils, and J.O. Young Radiotherapy for recurrent choroidal neovascularisation complicating age related macular degeneration Br J Ophthalmol 88 1 2004 114 119
    • (2004) Br J Ophthalmol , vol.88 , Issue.1 , pp. 114-119
    • Marcus, D.M.1    Sheils, W.C.2    Young, J.O.3
  • 357
    • 0035128938 scopus 로고    scopus 로고
    • External beam irradiation of subfoveal choroidal neovascularization complicating age-related macular degeneration: One-year results of a prospective, double-masked, randomized clinical trial
    • D.M. Marcus, W. Sheils, and M.H. Johnson External beam irradiation of subfoveal choroidal neovascularization complicating age-related macular degeneration: one-year results of a prospective, double-masked, randomized clinical trial Arch Ophthalmol 119 2 2001 171 180
    • (2001) Arch Ophthalmol , vol.119 , Issue.2 , pp. 171-180
    • Marcus, D.M.1    Sheils, W.2    Johnson, M.H.3
  • 358
    • 0033512396 scopus 로고    scopus 로고
    • Sham radiation in clinical trials assessing radiotherapy for exudative age-related macular degeneration
    • D.M. Marcus, M.W. Camp, and W.C. Sheils Sham radiation in clinical trials assessing radiotherapy for exudative age-related macular degeneration Retina 19 6 1999 525 530
    • (1999) Retina , vol.19 , Issue.6 , pp. 525-530
    • Marcus, D.M.1    Camp, M.W.2    Sheils, W.C.3
  • 359
    • 23144446773 scopus 로고    scopus 로고
    • Visual functioning and quality of life in the SubFoveal Radiotherapy Study (SFRADS): SFRADS report 2
    • M.R. Stevenson, P.M. Hart, and U. Chakravarthy Visual functioning and quality of life in the SubFoveal Radiotherapy Study (SFRADS): SFRADS report 2 Br J Ophthalmol 89 8 2005 1045 1051
    • (2005) Br J Ophthalmol , vol.89 , Issue.8 , pp. 1045-1051
    • Stevenson, M.R.1    Hart, P.M.2    Chakravarthy, U.3
  • 360
    • 0036340086 scopus 로고    scopus 로고
    • Visual outcomes in the subfoveal radiotherapy study: A randomized controlled trial of teletherapy for age-related macular degeneration
    • P.M. Hart, U. Chakravarthy, and G. Mackenzie Visual outcomes in the subfoveal radiotherapy study: a randomized controlled trial of teletherapy for age-related macular degeneration Arch Ophthalmol 120 8 2002 1029 1038
    • (2002) Arch Ophthalmol , vol.120 , Issue.8 , pp. 1029-1038
    • Hart, P.M.1    Chakravarthy, U.2    MacKenzie, G.3
  • 361
    • 0034026061 scopus 로고    scopus 로고
    • External beam radiotherapy in exudative age-related macular degeneration: A pooled analysis of phase i data
    • U. Chakravarthy, and G. MacKenzie External beam radiotherapy in exudative age-related macular degeneration: a pooled analysis of phase I data Br J Radiol 73 867 2000 305 313
    • (2000) Br J Radiol , vol.73 , Issue.867 , pp. 305-313
    • Chakravarthy, U.1    MacKenzie, G.2
  • 363
    • 33750304884 scopus 로고    scopus 로고
    • Proton beam irradiation for neovascular age-related macular degeneration
    • H.J. Zambarakji, A.M. Lane, and E. Ezra Proton beam irradiation for neovascular age-related macular degeneration Ophthalmology 113 11 2006 2012 2019
    • (2006) Ophthalmology , vol.113 , Issue.11 , pp. 2012-2019
    • Zambarakji, H.J.1    Lane, A.M.2    Ezra, E.3
  • 364
    • 84871194871 scopus 로고    scopus 로고
    • King's College Hospital NHS Trust http://clinicaltrials.gov/ct2/show/ NCT01006538. Accessed October 15
    • King's College Hospital NHS Trust. Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT). In: ClinicalTrials.gov. Available at: http://clinicaltrials.gov/ct2/show/NCT01006538. Accessed October 15, 2012.
    • (2012) Macular EpiRetinal Brachytherapy Versus Lucentis® only Treatment (MERLOT)
  • 367
    • 63249111858 scopus 로고    scopus 로고
    • Twelve-month safety and visual acuity results from a feasibility study of intraocular, epiretinal radiation therapy for the treatment of subfoveal CNV secondary to AMD
    • M.P. Avila, M.E. Farah, and A. Santos Twelve-month safety and visual acuity results from a feasibility study of intraocular, epiretinal radiation therapy for the treatment of subfoveal CNV secondary to AMD Retina 29 2 2009 157 169
    • (2009) Retina , vol.29 , Issue.2 , pp. 157-169
    • Avila, M.P.1    Farah, M.E.2    Santos, A.3
  • 368
    • 61749100479 scopus 로고    scopus 로고
    • Twelve-month short-term safety and visual-acuity results from a multicentre prospective study of epiretinal strontium-90 brachytherapy with bevacizumab for the treatment of subfoveal choroidal neovascularisation secondary to age-related macular degeneration
    • M.P. Avila, M.E. Farah, A. Santos, J.P. Duprat, B.W. Woodward, and J. Nau Twelve-month short-term safety and visual-acuity results from a multicentre prospective study of epiretinal strontium-90 brachytherapy with bevacizumab for the treatment of subfoveal choroidal neovascularisation secondary to age-related macular degeneration Br J Ophthalmol 93 3 2009 305 309
    • (2009) Br J Ophthalmol , vol.93 , Issue.3 , pp. 305-309
    • Avila, M.P.1    Farah, M.E.2    Santos, A.3    Duprat, J.P.4    Woodward, B.W.5    Nau, J.6
  • 369
    • 83055174622 scopus 로고    scopus 로고
    • 16-Gy low-voltage x-ray irradiation followed by as-needed ranibizumab therapy for AMD: 6-month outcomes of a "radiation-first" strategy
    • A.A. Moshfeghi, V.M. Canton, and H. Quiroz-Mercado 16-Gy low-voltage x-ray irradiation followed by as-needed ranibizumab therapy for AMD: 6-month outcomes of a "radiation-first" strategy Ophthalmic Surg Lasers Imaging 42 6 2011 460 467
    • (2011) Ophthalmic Surg Lasers Imaging , vol.42 , Issue.6 , pp. 460-467
    • Moshfeghi, A.A.1    Canton, V.M.2    Quiroz-Mercado, H.3
  • 370
    • 20444490737 scopus 로고    scopus 로고
    • Intereye difference in exudative age-related macular degeneration with minimally classic or occult subfoveal neovascularization after unilateral intravitreal injection of triamcinolone acetonide
    • J.B. Jonas, U.H. Spandau, B. Harder, U. Vossmerbaeumer, and B.A. Kamppeter Intereye difference in exudative age-related macular degeneration with minimally classic or occult subfoveal neovascularization after unilateral intravitreal injection of triamcinolone acetonide Am J Ophthalmol 139 6 2005 1073 1079
    • (2005) Am J Ophthalmol , vol.139 , Issue.6 , pp. 1073-1079
    • Jonas, J.B.1    Spandau, U.H.2    Harder, B.3    Vossmerbaeumer, U.4    Kamppeter, B.A.5
  • 371
    • 34250777149 scopus 로고    scopus 로고
    • The effect of intravitreal triamcinolone on foveal edema in exudative macular degeneration
    • M.C. Gillies, and J. Larsson The effect of intravitreal triamcinolone on foveal edema in exudative macular degeneration Am J Ophthalmol 144 1 2007 134 136
    • (2007) Am J Ophthalmol , vol.144 , Issue.1 , pp. 134-136
    • Gillies, M.C.1    Larsson, J.2
  • 372
    • 44949176621 scopus 로고    scopus 로고
    • Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration
    • A. Geltzer, A. Turalba, and S.S. Vedula Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration Cochrane Database Syst Rev 4 2007 CD005022
    • (2007) Cochrane Database Syst Rev , Issue.4 , pp. 005022
    • Geltzer, A.1    Turalba, A.2    Vedula, S.S.3
  • 373
    • 13444273215 scopus 로고    scopus 로고
    • Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization
    • R.F. Spaide, J. Sorenson, and L. Maranan Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization Ophthalmology 112 2 2005 301 304
    • (2005) Ophthalmology , vol.112 , Issue.2 , pp. 301-304
    • Spaide, R.F.1    Sorenson, J.2    Maranan, L.3
  • 374
    • 0042029477 scopus 로고    scopus 로고
    • Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization
    • R.F. Spaide, J. Sorenson, and L. Maranan Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization Ophthalmology 110 8 2003 1517 1525
    • (2003) Ophthalmology , vol.110 , Issue.8 , pp. 1517-1525
    • Spaide, R.F.1    Sorenson, J.2    Maranan, L.3
  • 375
    • 0029012421 scopus 로고
    • Photodynamic therapy of experimental choroidal neovascularization using lipoprotein-delivered benzoporphyrin
    • J.W. Miller, A.W. Walsh, and M. Kramer Photodynamic therapy of experimental choroidal neovascularization using lipoprotein-delivered benzoporphyrin Arch Ophthalmol 113 6 1995 810 818
    • (1995) Arch Ophthalmol , vol.113 , Issue.6 , pp. 810-818
    • Miller, J.W.1    Walsh, A.W.2    Kramer, M.3
  • 376
    • 0029864913 scopus 로고    scopus 로고
    • Liposomal benzoporphyrin derivative verteporfin photodynamic therapy. Selective treatment of choroidal neovascularization in monkeys
    • M. Kramer, J.W. Miller, and N. Michaud Liposomal benzoporphyrin derivative verteporfin photodynamic therapy. Selective treatment of choroidal neovascularization in monkeys Ophthalmology 103 3 1996 427 438
    • (1996) Ophthalmology , vol.103 , Issue.3 , pp. 427-438
    • Kramer, M.1    Miller, J.W.2    Michaud, N.3
  • 377
    • 0342632445 scopus 로고    scopus 로고
    • Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: One-year results of 2 randomized clinical trials - TAP report. Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group
    • Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group
    • Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials - TAP report. Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group Arch Ophthalmol 117 10 1999 1329 1345
    • (1999) Arch Ophthalmol , vol.117 , Issue.10 , pp. 1329-1345
  • 378
    • 0033804922 scopus 로고    scopus 로고
    • Transpupillary thermotherapy for age-related macular degeneration: Long-pulse photocoagulation, apoptosis, and heat shock proteins
    • M.A. Mainster, and E. Reichel Transpupillary thermotherapy for age-related macular degeneration: long-pulse photocoagulation, apoptosis, and heat shock proteins Ophthalmic Surg Lasers 31 5 2000 359 373
    • (2000) Ophthalmic Surg Lasers , vol.31 , Issue.5 , pp. 359-373
    • Mainster, M.A.1    Reichel, E.2
  • 379
    • 0035987218 scopus 로고    scopus 로고
    • Thermotherapy in the management of choroidal melanoma
    • J.G. Journee-de Korver, and J.E. Keunen Thermotherapy in the management of choroidal melanoma Prog Retin Eye Res 21 3 2002 303 317
    • (2002) Prog Retin Eye Res , vol.21 , Issue.3 , pp. 303-317
    • Journee-De Korver, J.G.1    Keunen, J.E.2
  • 380
    • 79953805728 scopus 로고    scopus 로고
    • Long-term follow-up 10 years after transpupillary thermotherapy (TTT) for small, posterior located malignant melanomas of the choroid
    • B.M. Stoffelns, K. Schoepfer, J. Vetter, A. Mirshahi, and H. Elflein [Long-term follow-up 10 years after transpupillary thermotherapy (TTT) for small, posterior located malignant melanomas of the choroid] Klin Monbl Augenheilkd 228 4 2011 277 283
    • (2011) Klin Monbl Augenheilkd , vol.228 , Issue.4 , pp. 277-283
    • Stoffelns, B.M.1    Schoepfer, K.2    Vetter, J.3    Mirshahi, A.4    Elflein, H.5
  • 381
    • 0034991606 scopus 로고    scopus 로고
    • Transpupillary thermotherapy of subfoveal occult choroidal neovascularization
    • A.H. Rogers, and E. Reichel Transpupillary thermotherapy of subfoveal occult choroidal neovascularization Curr Opin Ophthalmol 12 3 2001 212 215
    • (2001) Curr Opin Ophthalmol , vol.12 , Issue.3 , pp. 212-215
    • Rogers, A.H.1    Reichel, E.2
  • 382
    • 0035734289 scopus 로고    scopus 로고
    • Transpupillary thermotherapy (TTT) of occult choroidal neovascularization: A retrospective, noncomparative case series of fifty-seven eyes
    • C.H. Park, J.S. Duker, M.A. Mainster, C.A. Puliafito, and E. Reichel Transpupillary thermotherapy (TTT) of occult choroidal neovascularization: a retrospective, noncomparative case series of fifty-seven eyes Semin Ophthalmol 16 2 2001 66 69
    • (2001) Semin Ophthalmol , vol.16 , Issue.2 , pp. 66-69
    • Park, C.H.1    Duker, J.S.2    Mainster, M.A.3    Puliafito, C.A.4    Reichel, E.5
  • 383
    • 0035734290 scopus 로고    scopus 로고
    • Efficacy of transpupillary thermotherapy (TTT) in the treatment of occult subfoveal choroidal neovascularization in age-related macular degeneration
    • R.M. Ahuja, J.D. Benner, J.C. Schwartz, J.W. Butler, and S.M. Steidl Efficacy of transpupillary thermotherapy (TTT) in the treatment of occult subfoveal choroidal neovascularization in age-related macular degeneration Semin Ophthalmol 16 2 2001 81 85
    • (2001) Semin Ophthalmol , vol.16 , Issue.2 , pp. 81-85
    • Ahuja, R.M.1    Benner, J.D.2    Schwartz, J.C.3    Butler, J.W.4    Steidl, S.M.5
  • 384
    • 84871224487 scopus 로고    scopus 로고
    • Results from pivotal clinical trials released at AAO meeting: Specialists comment on their significance
    • Results from pivotal clinical trials released at AAO meeting: specialists comment on their significance Retinal Physician 2005(January) e100045
    • (2005) Retinal Physician , pp. 100045
  • 386
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • P.J. Rosenfeld, D.M. Brown, and J.S. Heier Ranibizumab for neovascular age-related macular degeneration N Engl J Med 355 14 2006 1419 1431
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 387
    • 79956191542 scopus 로고    scopus 로고
    • Bevacizumab versus ranibizumab for AMD
    • P.J. Rosenfeld Bevacizumab versus ranibizumab for AMD N Engl J Med 364 20 2011 1966 1967
    • (2011) N Engl J Med , vol.364 , Issue.20 , pp. 1966-1967
    • Rosenfeld, P.J.1
  • 388
    • 79956218863 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for neovascular age-related macular degeneration
    • CATT Research Group
    • CATT Research Group D.F. Martin, and M.G. Maguire Ranibizumab and bevacizumab for neovascular age-related macular degeneration N Engl J Med 364 20 2011 1897 1908
    • (2011) N Engl J Med , vol.364 , Issue.20 , pp. 1897-1908
    • Martin, D.F.1    Maguire, M.G.2
  • 389
    • 84863320414 scopus 로고    scopus 로고
    • Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: Two-year results
    • CATT Research Group
    • CATT Research Group D.F. Martin, M.G. Maguire, and S.L. Fine Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results Ophthalmology 119 7 2012 1388 1398
    • (2012) Ophthalmology , vol.119 , Issue.7 , pp. 1388-1398
    • Martin, D.F.1    Maguire, M.G.2    Fine, S.L.3
  • 390
    • 84871199860 scopus 로고    scopus 로고
    • CATT, meet IVAN: What have we learned from the ongoing ranibizumab vs bevacizumab trials?
    • A.J. Lotery CATT, meet IVAN: what have we learned from the ongoing ranibizumab vs bevacizumab trials? Retinal Physician 2012(June) e107120
    • (2012) Retinal Physician , pp. 107120
    • Lotery, A.J.1
  • 391
    • 52949129894 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: A report by the American Academy of Ophthalmology
    • M.S. Ip, I.U. Scott, and G.C. Brown Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: a report by the American Academy of Ophthalmology Ophthalmology 115 10 2008 1837 1846
    • (2008) Ophthalmology , vol.115 , Issue.10 , pp. 1837-1846
    • Ip, M.S.1    Scott, I.U.2    Brown, G.C.3
  • 394
    • 84871210391 scopus 로고    scopus 로고
    • United States Food and Drug Administration (FDA) Accessed October 1
    • United States Food and Drug Administration (FDA). FDA labeling information - Eylea. Available at: http://www.accessdata.fda.gov/drugsatfda- docs/label/2011/1253871bl.pdf. Accessed October 1, 2012.
    • (2012) FDA Labeling Information Eylea
  • 395
    • 58149478117 scopus 로고    scopus 로고
    • Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization
    • P. Pechan, H. Rubin, and M. Lukason Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization Gene Ther 16 1 2009 10 16
    • (2009) Gene Ther , vol.16 , Issue.1 , pp. 10-16
    • Pechan, P.1    Rubin, H.2    Lukason, M.3
  • 396
    • 79551622680 scopus 로고    scopus 로고
    • Preclinical safety evaluation of AAV2-sFLT01: A gene therapy for age-related macular degeneration
    • T.K. Maclachlan, M. Lukason, and M. Collins Preclinical safety evaluation of AAV2-sFLT01: a gene therapy for age-related macular degeneration Mol Ther 19 2 2011 326 334
    • (2011) Mol Ther , vol.19 , Issue.2 , pp. 326-334
    • MacLachlan, T.K.1    Lukason, M.2    Collins, M.3
  • 397
    • 84867403190 scopus 로고    scopus 로고
    • Preclinical safety evaluation of subretinal AAV2.sFlt-1 in non-human primates
    • C.M. Lai, M.J. Estcourt, and R.P. Himbeck Preclinical safety evaluation of subretinal AAV2.sFlt-1 in non-human primates Gene Ther 19 10 2012 999 1009
    • (2012) Gene Ther , vol.19 , Issue.10 , pp. 999-1009
    • Lai, C.M.1    Estcourt, M.J.2    Himbeck, R.P.3
  • 400
    • 84866306907 scopus 로고    scopus 로고
    • Safety and biodistribution of an EIAV-based gene therapy, RetinoStat(R), for age-related macular degeneration
    • K. Binley, P.S. Widdowson, and M. Kelleher Safety and biodistribution of an EIAV-based gene therapy, RetinoStat(R), for age-related macular degeneration Hum Gene Ther 23 9 2012 980 991
    • (2012) Hum Gene Ther , vol.23 , Issue.9 , pp. 980-991
    • Binley, K.1    Widdowson, P.S.2    Kelleher, M.3
  • 401
    • 0842307063 scopus 로고    scopus 로고
    • Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function
    • A.G. Marneros, D.R. Keene, and U. Hansen Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function EMBO J 23 1 2004 89 99
    • (2004) EMBO J , vol.23 , Issue.1 , pp. 89-99
    • Marneros, A.G.1    Keene, D.R.2    Hansen, U.3
  • 402
    • 2442654323 scopus 로고    scopus 로고
    • Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration
    • I.A. Bhutto, S.Y. Kim, and D.S. McLeod Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration Invest Ophthalmol Vis Sci 45 5 2004 1544 1552
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.5 , pp. 1544-1552
    • Bhutto, I.A.1    Kim, S.Y.2    McLeod, D.S.3
  • 403
    • 33744939462 scopus 로고    scopus 로고
    • Expression of endostatin in human choroidal neovascular membranes secondary to age-related macular degeneration
    • O. Tatar, K. Shinoda, and A. Adam Expression of endostatin in human choroidal neovascular membranes secondary to age-related macular degeneration Exp Eye Res 83 2 2006 329 338
    • (2006) Exp Eye Res , vol.83 , Issue.2 , pp. 329-338
    • Tatar, O.1    Shinoda, K.2    Adam, A.3
  • 404
    • 43549093349 scopus 로고    scopus 로고
    • Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration
    • I.A. Bhutto, K. Uno, C. Merges, L. Zhang, D.S. McLeod, and G.A. Lutty Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration Arch Ophthalmol 126 5 2008 670 678
    • (2008) Arch Ophthalmol , vol.126 , Issue.5 , pp. 670-678
    • Bhutto, I.A.1    Uno, K.2    Merges, C.3    Zhang, L.4    McLeod, D.S.5    Lutty, G.A.6
  • 405
    • 0035404544 scopus 로고    scopus 로고
    • Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin
    • K. Mori, A. Ando, and P. Gehlbach Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin Am J Pathol 159 1 2001 313 320
    • (2001) Am J Pathol , vol.159 , Issue.1 , pp. 313-320
    • Mori, K.1    Ando, A.2    Gehlbach, P.3
  • 406
    • 0034857729 scopus 로고    scopus 로고
    • Suppression of choroidal neovascularization by adeno-associated virus vector expressing angiostatin
    • C.C. Lai, W.C. Wu, and S.L. Chen Suppression of choroidal neovascularization by adeno-associated virus vector expressing angiostatin Invest Ophthalmol Vis Sci 42 10 2001 2401 2407
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.10 , pp. 2401-2407
    • Lai, C.C.1    Wu, W.C.2    Chen, S.L.3
  • 407
    • 0036798747 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents
    • A. Auricchio, K.C. Behling, and A.M. Maguire Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents Mol Ther 6 4 2002 490 494
    • (2002) Mol Ther , vol.6 , Issue.4 , pp. 490-494
    • Auricchio, A.1    Behling, K.C.2    Maguire, A.M.3
  • 408
    • 0038661164 scopus 로고    scopus 로고
    • Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment
    • K. Takahashi, Y. Saishin, and Y. Saishin Intraocular expression of endostatin reduces VEGF-induced retinal vascular permeability, neovascularization, and retinal detachment FASEB J 17 8 2003 896 898
    • (2003) FASEB J , vol.17 , Issue.8 , pp. 896-898
    • Takahashi, K.1    Saishin, Y.2    Saishin, Y.3
  • 409
    • 33746164355 scopus 로고    scopus 로고
    • EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV
    • K.S. Balaggan, K. Binley, and M. Esapa EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV Gene Ther 13 15 2006 1153 1165
    • (2006) Gene Ther , vol.13 , Issue.15 , pp. 1153-1165
    • Balaggan, K.S.1    Binley, K.2    Esapa, M.3
  • 410
    • 58849087072 scopus 로고    scopus 로고
    • Equine infectious anemia viral vector-mediated codelivery of endostatin and angiostatin driven by retinal pigmented epithelium-specific VMD2 promoter inhibits choroidal neovascularization
    • S. Kachi, K. Binley, and K. Yokoi Equine infectious anemia viral vector-mediated codelivery of endostatin and angiostatin driven by retinal pigmented epithelium-specific VMD2 promoter inhibits choroidal neovascularization Hum Gene Ther 20 1 2009 31 39
    • (2009) Hum Gene Ther , vol.20 , Issue.1 , pp. 31-39
    • Kachi, S.1    Binley, K.2    Yokoi, K.3
  • 411
    • 84856954338 scopus 로고    scopus 로고
    • Gene transfer for ocular neovascularization and macular edema
    • P.A. Campochiaro Gene transfer for ocular neovascularization and macular edema Gene Ther 19 2 2012 121 126
    • (2012) Gene Ther , vol.19 , Issue.2 , pp. 121-126
    • Campochiaro, P.A.1
  • 412
    • 16544386914 scopus 로고    scopus 로고
    • Experimental choroidal neovascularization is inhibited by subretinal administration of Endostatin
    • Q.L. Shang, J.X. Ma, J.S. Wei, Z.L. Shang, H.M. Xiu, and A.Q. Yang [Experimental choroidal neovascularization is inhibited by subretinal administration of Endostatin] Zhonghua Yan Ke Za Zhi 40 4 2004 266 271
    • (2004) Zhonghua Yan Ke Za Zhi , vol.40 , Issue.4 , pp. 266-271
    • Shang, Q.L.1    Ma, J.X.2    Wei, J.S.3    Shang, Z.L.4    Xiu, H.M.5    Yang, A.Q.6
  • 413
    • 36849018907 scopus 로고    scopus 로고
    • Endogenous endostatin inhibits choroidal neovascularization
    • A.G. Marneros, H. She, and H. Zambarakji Endogenous endostatin inhibits choroidal neovascularization FASEB J 21 14 2007 3809 3818
    • (2007) FASEB J , vol.21 , Issue.14 , pp. 3809-3818
    • Marneros, A.G.1    She, H.2    Zambarakji, H.3
  • 415
    • 3142744111 scopus 로고    scopus 로고
    • The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis
    • M. Kono, Y. Mi, and Y. Liu The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis J Biol Chem 279 28 2004 29367 29373
    • (2004) J Biol Chem , vol.279 , Issue.28 , pp. 29367-29373
    • Kono, M.1    Mi, Y.2    Liu, Y.3
  • 416
    • 84871246131 scopus 로고    scopus 로고
    • LPath, Inc. iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) http://clinicaltrials.gov/ct2/show/NCT01334255. Accessed October 15
    • LPath, Inc. iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects with Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV). In: ClinicalTrials.gov. Available at: http://clinicaltrials.gov/ct2/show/NCT01334255. Accessed October 15, 2012.
    • (2012) Subjects with Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV)
  • 417
    • 84871202242 scopus 로고    scopus 로고
    • LPath, Inc. Safety Study of iSONEP (Sonepcizumab/LT1009) http://clinicaltrials.gov/ct2/show/NCT00767949. Accessed October 15
    • LPath, Inc. Safety Study of iSONEP (Sonepcizumab/LT1009) to Treat Neovascular Age-Related Macular Degeneration. In: ClinicalTrials.gov. Available at: http://clinicaltrials.gov/ct2/show/NCT00767949. Accessed October 15, 2012.
    • (2012) Treat Neovascular Age-Related Macular Degeneration
  • 420
    • 79959925767 scopus 로고    scopus 로고
    • Anti-angiogenic effects of the receptor tyrosine kinase inhibitor, pazopanib, on choroidal neovascularization in rats
    • Y. Yafai, X.M. Yang, and M. Niemeyer Anti-angiogenic effects of the receptor tyrosine kinase inhibitor, pazopanib, on choroidal neovascularization in rats Eur J Pharmacol 666 1-3 2011 12 18
    • (2011) Eur J Pharmacol , vol.666 , Issue.13 , pp. 12-18
    • Yafai, Y.1    Yang, X.M.2    Niemeyer, M.3
  • 421
    • 84865751223 scopus 로고    scopus 로고
    • Inhibitory Activity of ranibizumab, sorafenib, and pazopanib on light-induced overexpression of platelet-derived growth factor and vascular endothelial growth factor A and the vascular endothelial growth factor A receptors 1 and 2 and neuropilin 1 and 2
    • M. Kernt, S. Thiele, and A.S. Neubauer Inhibitory Activity of ranibizumab, sorafenib, and pazopanib on light-induced overexpression of platelet-derived growth factor and vascular endothelial growth factor A and the vascular endothelial growth factor A receptors 1 and 2 and neuropilin 1 and 2 Retina 32 8 2012 1652 1663
    • (2012) Retina , vol.32 , Issue.8 , pp. 1652-1663
    • Kernt, M.1    Thiele, S.2    Neubauer, A.S.3
  • 422
    • 84871248421 scopus 로고    scopus 로고
    • Pazopanib explored for neovascular age-related macular degeneration
    • L. Charters Pazopanib explored for neovascular age-related macular degeneration Ophthalmology Times 2010;March 1
    • (2010) Ophthalmology Times
    • Charters, L.1
  • 425
    • 84860883878 scopus 로고    scopus 로고
    • DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
    • V. Tarallo, Y. Hirano, and B.D. Gelfand DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Cell 149 4 2012 847 859
    • (2012) Cell , vol.149 , Issue.4 , pp. 847-859
    • Tarallo, V.1    Hirano, Y.2    Gelfand, B.D.3
  • 426
    • 84871202185 scopus 로고    scopus 로고
    • Eyeing the inflammasome
    • T. Fulmer Eyeing the inflammasome SciBX 5 20 2012 1 3
    • (2012) SciBX , vol.5 , Issue.20 , pp. 1-3
    • Fulmer, T.1
  • 427
    • 84860671364 scopus 로고    scopus 로고
    • NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
    • S.L. Doyle, M. Campbell, and E. Ozaki NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components Nat Med 18 5 2012 791 798
    • (2012) Nat Med , vol.18 , Issue.5 , pp. 791-798
    • Doyle, S.L.1    Campbell, M.2    Ozaki, E.3
  • 428
    • 0034086115 scopus 로고    scopus 로고
    • The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
    • J.R. Sparrow, K. Nakanishi, and C.A. Parish The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells Invest Ophthalmol Vis Sci 41 7 2000 1981 1989
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.7 , pp. 1981-1989
    • Sparrow, J.R.1    Nakanishi, K.2    Parish, C.A.3
  • 429
    • 0035040640 scopus 로고    scopus 로고
    • Blue light-induced apoptosis of A2E-containing RPE: Involvement of caspase-3 and protection by Bcl-2
    • J.R. Sparrow, and B. Cai Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2 Invest Ophthalmol Vis Sci 42 6 2001 1356 1362
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.6 , pp. 1356-1362
    • Sparrow, J.R.1    Cai, B.2
  • 430
    • 18044366931 scopus 로고    scopus 로고
    • RPE lipofuscin and its role in retinal pathobiology
    • J.R. Sparrow, and M. Boulton RPE lipofuscin and its role in retinal pathobiology Exp Eye Res 80 5 2005 595 606
    • (2005) Exp Eye Res , vol.80 , Issue.5 , pp. 595-606
    • Sparrow, J.R.1    Boulton, M.2
  • 433
    • 33644795859 scopus 로고    scopus 로고
    • Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: A potential therapy for treatment of lipofuscin-based retinal diseases
    • R.A. Radu, Y. Han, and T.V. Bui Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases Invest Ophthalmol Vis Sci 46 12 2005 4393 4401
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , Issue.12 , pp. 4393-4401
    • Radu, R.A.1    Han, Y.2    Bui, T.V.3
  • 434
    • 84871217632 scopus 로고    scopus 로고
    • News in review: Fenretinide fights dry AMD
    • M. Karmel News in review: fenretinide fights dry AMD EyeNet Magazine October 2010
    • (2010) EyeNet Magazine
    • Karmel, M.1
  • 435
    • 33748937039 scopus 로고    scopus 로고
    • Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice
    • A. Maeda, T. Maeda, and M. Golczak Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice Mol Pharmacol 70 4 2006 1220 1229
    • (2006) Mol Pharmacol , vol.70 , Issue.4 , pp. 1220-1229
    • Maeda, A.1    Maeda, T.2    Golczak, M.3
  • 436
    • 84855205404 scopus 로고    scopus 로고
    • Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator
    • R. Kubota, N.L. Boman, R. David, S. Mallikaarjun, S. Patil, and D. Birch Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator Retina 32 1 2012 183 188
    • (2012) Retina , vol.32 , Issue.1 , pp. 183-188
    • Kubota, R.1    Boman, N.L.2    David, R.3    Mallikaarjun, S.4    Patil, S.5    Birch, D.6
  • 437
    • 79961005068 scopus 로고    scopus 로고
    • Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
    • J.D. Ding, L.V. Johnson, and R. Herrmann Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration Proc Natl Acad Sci U S A 108 28 2011 E279 E287
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.28
    • Ding, J.D.1    Johnson, L.V.2    Herrmann, R.3
  • 438
    • 79955056247 scopus 로고    scopus 로고
    • Treatment of geographic atrophy by the topical administration of OT-551: Results of a phase II clinical trial
    • W.T. Wong, W. Kam, and D. Cunningham Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial Invest Ophthalmol Vis Sci 51 12 2010 6131 6139
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.12 , pp. 6131-6139
    • Wong, W.T.1    Kam, W.2    Cunningham, D.3
  • 439
    • 33644872951 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase i trial of CNTF delivered by encapsulated cell intraocular implants
    • P.A. Sieving, R.C. Caruso, and W. Tao Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants Proc Natl Acad Sci U S A 103 10 2006 3896 3901
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.10 , pp. 3896-3901
    • Sieving, P.A.1    Caruso, R.C.2    Tao, W.3
  • 440
    • 79956021004 scopus 로고    scopus 로고
    • Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress
    • R.J. Collier, Y. Patel, and E.A. Martin Agonists at the serotonin receptor (5-HT(1A)) protect the retina from severe photo-oxidative stress Invest Ophthalmol Vis Sci 52 5 2011 2118 2126
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.5 , pp. 2118-2126
    • Collier, R.J.1    Patel, Y.2    Martin, E.A.3
  • 441
  • 443
    • 80555133359 scopus 로고    scopus 로고
    • RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death
    • Y. Murakami, J.W. Miller, and D.G. Vavvas RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death Oncotarget 2 6 2011 497 509
    • (2011) Oncotarget , vol.2 , Issue.6 , pp. 497-509
    • Murakami, Y.1    Miller, J.W.2    Vavvas, D.G.3
  • 444
    • 78650718758 scopus 로고    scopus 로고
    • Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
    • G. Trichonas, Y. Murakami, and A. Thanos Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis Proc Natl Acad Sci U S A 107 50 2010 21695 21700
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.50 , pp. 21695-21700
    • Trichonas, G.1    Murakami, Y.2    Thanos, A.3
  • 445
    • 80054780693 scopus 로고    scopus 로고
    • Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats
    • J. Suzuki, A. Manola, and Y. Murakami Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats Invest Ophthalmol Vis Sci 52 9 2011 6565 6571
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.9 , pp. 6565-6571
    • Suzuki, J.1    Manola, A.2    Murakami, Y.3
  • 446
    • 79955940404 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment
    • T. Nakazawa, M. Kayama, and M. Ryu Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment Invest Ophthalmol Vis Sci 52 3 2011 1384 1391
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.3 , pp. 1384-1391
    • Nakazawa, T.1    Kayama, M.2    Ryu, M.3
  • 447
    • 84857643783 scopus 로고    scopus 로고
    • Embryonic stem cell trials for macular degeneration: A preliminary report
    • S.D. Schwartz, J.P. Hubschman, and G. Heilwell Embryonic stem cell trials for macular degeneration: a preliminary report Lancet 379 9817 2012 713 720
    • (2012) Lancet , vol.379 , Issue.9817 , pp. 713-720
    • Schwartz, S.D.1    Hubschman, J.P.2    Heilwell, G.3
  • 448
    • 47549104714 scopus 로고    scopus 로고
    • Vision improvement in retinal degeneration patients by implantation of retina together with retinal pigment epithelium
    • N.D. Radtke, R.B. Aramant, H.M. Petry, P.T. Green, D.J. Pidwell, and M.J. Seiler Vision improvement in retinal degeneration patients by implantation of retina together with retinal pigment epithelium Am J Ophthalmol 146 2 2008 172 182
    • (2008) Am J Ophthalmol , vol.146 , Issue.2 , pp. 172-182
    • Radtke, N.D.1    Aramant, R.B.2    Petry, H.M.3    Green, P.T.4    Pidwell, D.J.5    Seiler, M.J.6
  • 449
    • 82355170259 scopus 로고    scopus 로고
    • Early events in xenograft development from the human embryonic stem cell line HS181 - Resemblance with an initial multiple epiblast formation
    • K. Gertow, J. Cedervall, and S. Jamil Early events in xenograft development from the human embryonic stem cell line HS181 - resemblance with an initial multiple epiblast formation PLoS One 6 11 2011 e27741
    • (2011) PLoS One , vol.6 , Issue.11 , pp. 27741
    • Gertow, K.1    Cedervall, J.2    Jamil, S.3
  • 450
    • 78650902662 scopus 로고    scopus 로고
    • Optogenetics
    • K. Deisseroth Optogenetics Nat Methods 8 1 2011 26 29
    • (2011) Nat Methods , vol.8 , Issue.1 , pp. 26-29
    • Deisseroth, K.1
  • 451
    • 44349103098 scopus 로고    scopus 로고
    • Light-activated channels targeted to on bipolar cells restore visual function in retinal degeneration
    • P.S. Lagali, D. Balya, and G.B. Awatramani Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration Nat Neurosci 11 6 2008 667 675
    • (2008) Nat Neurosci , vol.11 , Issue.6 , pp. 667-675
    • Lagali, P.S.1    Balya, D.2    Awatramani, G.B.3
  • 452
    • 61549136093 scopus 로고    scopus 로고
    • Remodeling of cone photoreceptor cells after rod degeneration in rd mice
    • B. Lin, R.H. Masland, and E. Strettoi Remodeling of cone photoreceptor cells after rod degeneration in rd mice Exp Eye Res 88 3 2009 589 599
    • (2009) Exp Eye Res , vol.88 , Issue.3 , pp. 589-599
    • Lin, B.1    Masland, R.H.2    Strettoi, E.3
  • 453
    • 85027946862 scopus 로고    scopus 로고
    • Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness
    • M.M. Doroudchi, K.P. Greenberg, and J. Liu Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness Mol Ther 19 7 2011 1220 1229
    • (2011) Mol Ther , vol.19 , Issue.7 , pp. 1220-1229
    • Doroudchi, M.M.1    Greenberg, K.P.2    Liu, J.3
  • 454
    • 79955436204 scopus 로고    scopus 로고
    • Gene therapy in ophthalmology: Validation on cultured retinal cells and explants from postmortem human eyes
    • M. Fradot, V. Busskamp, and V. Forster Gene therapy in ophthalmology: validation on cultured retinal cells and explants from postmortem human eyes Hum Gene Ther 22 5 2011 587 593
    • (2011) Hum Gene Ther , vol.22 , Issue.5 , pp. 587-593
    • Fradot, M.1    Busskamp, V.2    Forster, V.3
  • 455
    • 84856191188 scopus 로고    scopus 로고
    • Improving quality of life in patients with end-stage age-related macular degeneration: Focus on miniature ocular implants
    • M.A. Singer, N. Amir, A. Herro, S.S. Porbandarwalla, and J. Pollard Improving quality of life in patients with end-stage age-related macular degeneration: focus on miniature ocular implants Clin Ophthalmol 6 2012 33 39
    • (2012) Clin Ophthalmol , vol.6 , pp. 33-39
    • Singer, M.A.1    Amir, N.2    Herro, A.3    Porbandarwalla, S.S.4    Pollard, J.5


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