ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease

Journal of Biological Chemistry

Volumn 276, Issue 15, 2001, Pages 11766-11774

  Sun, Hui ^a   Nathans, Jeremy ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHROMOPHORES; GELS; PHOTOOXIDATION; PROTEINS;

PHOTODAMAGE; PHOTORECEPTOR CELLS;

ADENOSINETRIPHOSPHATE;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; PERIPHERIN; PROTEIN; PROTEIN A2E; PROTEIN ABCR; PROTEIN ROM 1; RETINAL; RETINOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHROMATOPHORE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; IN VITRO STUDY; LIGHT EXPOSURE; NONHUMAN; PATHOGENESIS; PHOTOOXIDATION; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RETINA DISEASE; RETINA ROD; STARGARDT DISEASE; ANIMAL; CATTLE; CONGENITAL CORNEA DYSTROPHY; DRUG EFFECT; METABOLISM; OXIDATIVE STRESS; RADIATION EXPOSURE; RETINA ROD OUTER SEGMENT; ULTRAVIOLET RADIATION;

ANIMALIA;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CATTLE; CORNEAL DYSTROPHIES, HEREDITARY; OXIDATIVE STRESS; RETINALDEHYDE; ROD OUTER SEGMENTS; ULTRAVIOLET RAYS;

EID: 0035853719     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010152200     Document Type: Article

References (96)

1. Verhoeff, F. H., and Bell, L. (1916) Proc. Am. Acad. Arts Sci. 51, 630-818
2. Duke-Elder, S. (1954) Textbook of Ophthalmology, Volume VI, pp. 6494-6517, C. V. Mosby, St. Louis, MO
3. Clark, B., Johnson, M. L., and Dreher, R. H. (1946) Am. J. Ophthalmol. 29, 828-836
4. Cordes, F. C. (1944) Am. J. Ophthalmol. 27, 803-816
5. Smith, H. E. (1944) U. S. Naval Med. Bull. 42, 675-680
6. Borley, W. E., McAlester, A. W., and Lower, R. A. (1945) U. S. Naval Med. Bull. 45, 511-516
7. Rosen, E. (1948) Br. J. Ophthalmol. 32, 23-35
8. Marlor, R. L., Blais, B. R., Preston, F. R., and Boyden, D. G. (1973) Investig. Ophthalmol. 12, 5-16
9. Young, R. W. (1988) Surv. Ophthalmol. 32, 252-269
10. Taylor, H. R., Munoz, B., West, S., Bressler, N. M., Bressler, S. B., and Rosenthal, F. S. (1990) Trans. Am. Ophthalmol. Soc. 88, 163-178
11. Taylor, H. R., West, S., Munoz, B., Rosenthal, F. S., Bressler, S. B., and Bressler, N. M. (1992) Arch. Ophthalmol. 110, 99-104
12. Cruickshanks, K. J., Klein, R., and Wein, B. E. K. (1993) Arch. Ophthalmol. 111, 514-518
13. Lanum, J. (1978) Surv. Ophthalmol. 22, 221-249
14. Oranisciak, D. T., and Winkler, B. S. (1994) Prog. Retinal Eye Res. 13, 1-29
15. Reme, C. E., Hafezi, F., Marti, A., Munz, K., and Reinboth, J. J. (1998) in The Retinal Pigment Epithelium (Marmor, M. F., and Wolfensberger, T. J., eds) pp. 563-586, Oxford University Press, Oxford
16. Ham, W. T., Mueller, H. A., and Sliney, D. H. (1976) Nature 260, 153-155
17. Rapp, L. M., Tolman, B. L., and Dhindsa, H. S. (1990) Investig. Ophthalmol. Vis. Sci. 31, 1186-1190
18. Rapp, L. M., and Smith, S. C. (1992) Investig. Ophthalmol. Vis. Sci. 33, 3367-3377
19. Gorgels, G. M. F., and van Norren, D. (1995) Investig. Ophthalmol. Vis. Sci. 36, 851-863
20. Noell, W. K., Walker, V. S., Kang, B. S., and Berman, S. (1966) Investig. Ophthalmol. Vis. Sci. 5, 450-473
21. Williams, T. P., and Howell, W. L. (1983) Investig. Ophthalmol. Vis. Sci. 24, 285-287
22. Noell, W. K. (1980) Vision Res. 20, 1163-1171
23. Lion, Y., Delmelle, M., and van de Vorst, A. (1976) Nature 263, 442-443
24. Delmelle, M. (1978) Photochem. Photobiol. 27, 731-734
25. Delmelle, M. (1978) Photochem. Photobiol. 28, 357-360
26. Pogozheva, I. D., Federovich, I. B., Ostrosvskii, M. A., and Emanual, N. M. (1981) Biofizika 26, 398-403
27. Starostin, A. V., Federovich, I. B., and Ostrovskii, M. A. (1985) Biofizika 30, 995-999
28. Murata, M., and Kawanashi, S. (2000) J. Biol. Chem. 275, 2003-2008
29. Ostrovskii, M. A., and Fedorovich, I. B. (1994) Biofizika 39, 13-25
30. Noell, W. K., Delmelle, M. C., and Albrecht, R. (1971) Science 172, 72-75
31. Noell, W. K., and Albrecht, R. (1971) Science 172, 76-80
32. Grimm, C., Wenzel, A., Hafezi, F., Yu, S., Redmond, T. M., and Reme, C. (2000) Nat. Genet. 25, 63-66
33. Organisciak, D. T., Darrow, R. M., Jiang, Y., Marak, G. E., and Blanks, J. C. (1992) Investig. Ophthalmol. Vis. Sci. 33, 1599-1609
34. Reme, C. E., Braschler, U. F., Roberts, J., and Dillon, J. (1991) Photochem. Photobiol. 54, 137-142
35. Kagan, V. E., Shvedova, A. A., Novikov, K. N., and Kozlov, Y. P. (1973) Biochim. Biophys. Acta 330, 76-79
36. Wiegand, R. D., Giusto, N. M., Rapp, L. M., and Anderson, R. E. (1983) Investig. Ophthalmol. Vis. Sci. 24, 1433-1435
37. Darrow, R. A., Darrow, R. M., and Organisciak, D. T. (1997) Curr. Eye Res. 16, 144-151
38. Gaillard, E. R., Atherton, S. J., Eldred, G., and Dillon, J. (1995) Photochem, Photobiol. 61, 448-453
39. Rozanowska, M., Jarvis-Evans, J., Korytowski, W., Boulton, M. E., Burke, J. M., and Sarna, T. (1995) J. Biol. Chem. 270, 18825-18830
40. Eldred, G. E., and Lasky, M. R. (1993) Nature 361, 724-726
41. Eldred, G. E. (1998) in The Retinal Pigment Epithelium (Marmor, M. F., and Wolfensberger, T. J., eds) pp. 651-668, Oxford University Press, Oxford
42. Parish, C. A., Hashimoto, M., Nakanishi, K., Dillon, J., and Sparrow, J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14609-14613
43. Mata, N. L., Weng, J., and Travis, G. H. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7154-7159
44. Liu, J., Itagaki, Y., Ben-Shabat, S., Nakanishi, K., and Sparrow, J. R. (2000) J. Biol. Chem. 275, 29354-29360
45. Sparrow, J. R., Nakanishi, K., and Parish, C. A. (2000) Investig. Ophthalmol. Vis. Sci. 41, 1981-1989
46. Allikmets, R., Singh, N., Sun, H., Shroyer, N. F., Hutchinson, A., Chidambaram, A., Gerrard, B., Baird, L., Stauffer, D., Peiffer, A., Rattner, A., Smallwood, P., Li, Y., Anderson, K. L., Lewis, R. A., Nathans, J., Leppert, M., Dean, M., and Lupski, J. R. (1997) Nat. Genet. 15, 236-246
47. Nasonkin, I., Illing, M., Koehler, M. R., Schmid, M., Molday, R. S., and Weber, B. H. F. (1998) Hum. Genet. 102, 21-26
48. Rozet, J.-M., Gerber, S., Souied, E., Perrault, I., Chatelin, S., Ghazi, I., Leowski, C., Dufier, J.-L., Munnich, A., and Kaplan, J. (1998) Eur. J. Hum. Genet. 6, 291-295
49. Stone, E. M., Webster, A. R., Vandenburgh, K., Streb, L. M., Hockey, R. R. Lotery, A. J., and Sheffield, V. C. (1998) Nat. Genet. 20, 328-329
50. Lewis, R. A., Shroyer, N. F., Singh, N., Allikmets, R., Hutchinson, A., Li, Y., Lupski, J. R., Leppert, M., and Dean, M. (1999) Am. J. Hum. Genet. 64, 422-434
51. Sun, H., Smallwood, P. M., and Nathans, J. (2000) Nat. Genet. 26, 242-246
52. Illing, M., Molday, L. L., and Molday, R. S. (1997) J. Biol. Chem. 272, 10303-10310
53. Sun, H., and Nathans, J. (1997) Nat. Genet. 17, 15-16
54. Molday, L. L., Rabin, A. R., and Molday, R. S. (2000) Nat. Genet. 25, 257-258
55. Klein, B. A., and Krill, A. E. (1967) Am. J. Ophthalmol. 64, 3-23
56. Eagle, R. C., Lucier, A. C., Bernardino, V. B., and Yanoff, M. (1980) Ophthalmology 87, 1189-1200
57. Blacharski, P. A. (1988) in Retinal Dystrophies and Degenerations (Newsome, D. A., ed) pp 135-159, Raven Press, New York
58. Fishman, G. A., Farbman, J. S., and Alexander, K. R. (1991) Ophthalmology 98, 957-962
59. Steinmetz, R. L., Garner, A., Maguirre, J. I., and Bird, A. C. (1991) Ophthalmology 98, 953-956
60. Delori, F. C., Dorey, C. K., Staurenghi, G., Arend, O., Goger, D. G., and Weiter, J. J. (1995) Investig. Ophthalmol. Vis. Sci. 36, 718-729
61. Delori, F. C., Staurenghi, G., Arend, O., Dorey, C. K., Goger, D. G., and Weiter, J. J. (1995) Investig. Ophthalmol. Vis. Sci. 36, 2327-2331
62. Cremers, F. P. M., van de Pol, D. J. R., van Driel, M., den Hollander, A. I., van Haren, F. J. J., Knoers, N. V. A. M., Tijmes, N., Bergen, A. A. B., Rohrschneider, K., Blankenagel, A., Pinckers, A. J. L. G., Deutman, A. F., and Hoyng, C. B. (1998) Hum. Mol. Genet. 7, 355-362
63. Martinez-Mir, A., Paloma, E., Allikmets, R., Ayoso, C., del Rio, T., Dean, M., Gonzalez-Duarte, R., and Balcells, S. (1998) Nat. Genet. 18, 11-12
64. Rozet, J.-M., Gerber, S., Ghazi, I., Perrault, I., Ducroq, D., Souied, E., Cabot, A., Dufier, J.-L., Munnich, A., and Kaplan, J. (1999) J. Med. Genet. 36, 447-451
65. Allikmets, R., and the International ABCR Screening Consortium (2000) Am. J. Hum. Genet. 67, 487-491
66. Sun, H., Molday, R. S., and Nathans, J. (1999) J. Biol. Chem. 274, 8269-8281
67. Ahn, J., Wong, J. T., and Molday, R. S. (2000) J. Biol. Chem. 275, 20399-20405
68. Weng, J., Mata, N. L., Azarian, S. M., Tzekov, R. D., Birch, D. G., and Travis, G. H. (1999) Cell 98, 13-23
69. Papermaster, D. S. (1982) Methods Enzymol. 81, 48-52
70. Rattner, A., Smallwood, P. M., and Nathans, J. (2000) J. Biol. Chem. 275, 11034-11043
71. Wyszecki, G., and Stiles, W. S. (1982) Color Science. Concepts and Methods, Quantitative Data and Formulas. 2nd Ed., pp. 108-111, John Wiley & Sons, New York
72. Keys, S. A., and Zimmerman, W. F. (1999) Exp. Eye Res. 68, 693-702
73. Palczewski, K., Jager, S., Buczylko, J., Crouch, R. K., Bredberg, D. L., Hofmann, K. P., Asson-Batres, M. A., and Saari, J. C. (1994) Biochemistry 33, 13741-13750
74. Farnsworth, C., and Dratz, E. A. (1976) Biochim. Biophys. Acta 443, 556-570
75. Baylor, D. A., and Lamb, T. D. (1982) J. Physiol. 328, 49-71
76. Cohen, G. B., Oprian, D. D., and Robinson, P. R. (1992) Biochemistry 31, 12592-12601
77. Surya, A., Foster, K. W., and Knox, B. E. (1995) J. Biol. Chem. 270, 5024-5031
78. Jager, S. Palczewski, K., and Hofmann, K. P. (1996) Biochemistry 35, 2901-2908
79. Alpern, M. (1971) J. Physiol. (Lond.) 217, 447-471
80. Alpern, M., Rushton, W. A. H., and Torii, S. (1970) J. Physiol. (Lond.) 207, 449-461
81. Zimmerman, W. H., Yost, M. T., and Daemen, F. J. M. (1974) Nature 250, 66-67
82. Lamb, T. D. (1980) Nature 87, 349-351
83. Fain, G. L., Matthews, H. R., and Cornwall, M. C. (1996) Trends Neurosci. 19, 502-507
84. Saari, J. C., Garwin, G. G., Van Hooser, J. P., and Palczewski, K. (1998) Vision, Res. 38, 1325-1333
85. Kaplan, M. W. (1985) Exp. Eye Res. 40, 721-729
86. Kuwabara, T., and Gorn, R. A. (1968) Arch. Ophthalmol. 79, 69-78
87. Sykes, S. M., Robison, W. G., Waxler, M., and Kuwabara, T. (1981) Investig. Ophthalmol. Vis. Sci. 20, 425-434
88. Linsenmeier, R. A. (1986) J. Gen. Physiol. 88, 521-542
89. Ahmed, J., Braun, R. D., Dunn, R., and Linsenmeier, R. A. (1993) Investig. Ophthalmol. Vis. Sci. 34, 516-521
90. Williams, T. P., and Penn, J. S. (1985) J. Gen. Physiol. 86, 413-422
91. Hsu, S.-C., and Molday, R. S. (1990) J. Biol. Chem. 265, 13308-13313
92. Hsu, S.-C., and Molday, R. S. (1994) J. Biol. Chem. 269, 17954-17959
93. Molday, R. S. (1998) Investig. Ophthalmol. Vis. Sci. 39, 2491-2513
94. Besharse, J. C., and Defoe, D. M. (1998) in The Retinal Pigment Epithelium (Marmor, M. F., and Wolfensberger, T. J., eds) pp. 152-172, Oxford University Press, Oxford
95. Burke, J. M. (1998) in The Retinal Pigment Epithelium (Marmor, M. F., and Wolfensberger, T. J., eds) pp. 86-102, Oxford University Press, Oxford
96. Cooper, A., Dixon, S. F., Nutley, M. A., and Robb, J. L. (1987) J. Am. Chem. Soc. 109, 7254-7263