Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production

European Journal of Immunology

Volumn 42, Issue 10, 2012, Pages 2760-2770

  Landego, Ivan ^a   Jayachandran, Nipun ^a   Wullschleger, Stephan ^b   Zhang, Ting Ting ^a   Gibson, Ian W ^a   Miller, Angela ^a   Alessi, Dario R ^b   Marshall, Aaron J ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Antigen receptor; Autoantibody; B lymphocyte; PI 3 kinase; Tandem PH domain containing protein (TAPP)

Indexed keywords

ADAPTOR PROTEIN; ANTINUCLEAR ANTIBODY; AUTOANTIBODY; CD86 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; PHOSPHATIDYLINOSITOL 3,4 BISPHOSPHATE; PROTEIN KINASE B; TANDEM PH DOMAIN CONTAINING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CROSS LINKING; FEMALE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, CD86; AUTOANTIBODIES; B-LYMPHOCYTES; BINDING SITES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; FEEDBACK, PHYSIOLOGICAL; FEMALE; GLOMERULONEPHRITIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING;

EID: 84867214110     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242371     Document Type: Article

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