Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Jun, Gyungah ^a,b   Nicolaou, Michael ^a   Morrison, Margaux A ^c,d   Buros, Jacqueline ^a   Morgan, Denise J ^d   Radeke, Monte J ^e   Yonekawa, Yoshihiro ^c,f   Tsironi, Evangelia E ^g   Kotoula, Maria G ^g   Zacharaki, Fani ^g   Mollema, Nissa ^h   Yuan, Yang ^h   Miller, Joan W ^c   Haider, Neena B ^h   Hageman, Gregory S ^d   Kim, Ivana K ^c   Schaumberg, Debra A ⁱ   Farrer, Lindsay A ^a,b   DeAngelis, Margaret M ^c,d  

^a BOSTON UNIVERSITY   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g UNIVERSITY OF THESSALY   (Greece)

^h UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME; IMMUNOGLOBULIN RECEPTOR; NERVE PROTEIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RORA PROTEIN, HUMAN; ROUNDABOUT RECEPTOR;

ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE CLASSIFICATION; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GREECE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; RAR RELATED ORPHAN RECEPTOR ALPHA GENE; RETINA MACULA AGE RELATED DEGENERATION; ROUNDABOUT 1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; ANIMAL; EXUDATIVE MACULAR DEGENERATION; EYE; GENETIC EPISTASIS; GENETIC PREDISPOSITION; GENETICS; GEOGRAPHIC ATROPHY; METABOLISM; RETINA MACULA DEGENERATION;

AGED; ANIMALS; CHROMATIN IMMUNOPRECIPITATION; EPISTASIS, GENETIC; EYE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GEOGRAPHIC ATROPHY; HUMANS; MACULAR DEGENERATION; MALE; MICE; NERVE TISSUE PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, IMMUNOLOGIC; TRANSCRIPTOME; WET MACULAR DEGENERATION;

EID: 80053590169     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025775     Document Type: Article

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