메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages

A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD59 ANTIGEN; PARVOVIRUS VECTOR; COMPLEMENT MEMBRANE ATTACK COMPLEX;

EID: 79955721853     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019078     Document Type: Article
Times cited : (109)

References (41)
  • 1
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • de Jong PT, (2006) Age-related macular degeneration. N Engl J Med 355: 1474-1485.
    • (2006) N Engl J Med , vol.355 , pp. 1474-1485
    • de Jong, P.T.1
  • 3
    • 77249147331 scopus 로고    scopus 로고
    • The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited
    • Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, et al. (2010) The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 29: 95-112.
    • (2010) Prog Retin Eye Res , vol.29 , pp. 95-112
    • Anderson, D.H.1    Radeke, M.J.2    Gallo, N.B.3    Chapin, E.A.4    Johnson, P.T.5
  • 4
    • 0035849176 scopus 로고    scopus 로고
    • Complement. Second of two parts
    • Walport MJ, (2001) Complement. Second of two parts. N Engl J Med 344: 1140-1144.
    • (2001) N Engl J Med , vol.344 , pp. 1140-1144
    • Walport, M.J.1
  • 5
    • 0035810399 scopus 로고    scopus 로고
    • Complement. First of two parts
    • Walport MJ, (2001) Complement. First of two parts. N Engl J Med 344: 1058-1066.
    • (2001) N Engl J Med , vol.344 , pp. 1058-1066
    • Walport, M.J.1
  • 6
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV, (2002) A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 134: 411-431.
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 7
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, et al. (2005) A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 102: 7227-7232.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3    Hancox, L.S.4    Taiber, A.J.5
  • 8
    • 0028014275 scopus 로고
    • Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells
    • Benzaquen LR, Nicholson-Weller A, Halperin JA, (1994) Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells. J Exp Med 179: 985-992.
    • (1994) J Exp Med , vol.179 , pp. 985-992
    • Benzaquen, L.R.1    Nicholson-Weller, A.2    Halperin, J.A.3
  • 9
    • 0027217325 scopus 로고
    • Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells
    • Halperin JA, Taratuska A, Nicholson-Weller A, (1993) Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells. J Clin Invest 91: 1974-1978.
    • (1993) J Clin Invest , vol.91 , pp. 1974-1978
    • Halperin, J.A.1    Taratuska, A.2    Nicholson-Weller, A.3
  • 10
    • 33846507393 scopus 로고    scopus 로고
    • CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration
    • Bora NS, Kaliappan S, Jha P, Xu Q, Sivasankar B, et al. (2007) CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration. J Immunol 178: 1783-1790.
    • (2007) J Immunol , vol.178 , pp. 1783-1790
    • Bora, N.S.1    Kaliappan, S.2    Jha, P.3    Xu, Q.4    Sivasankar, B.5
  • 11
    • 0025179976 scopus 로고
    • Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers
    • Meri S, Morgan BP, Davies A, Daniels RH, Olavesen MG, et al. (1990) Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology 71: 1-9.
    • (1990) Immunology , vol.71 , pp. 1-9
    • Meri, S.1    Morgan, B.P.2    Davies, A.3    Daniels, R.H.4    Olavesen, M.G.5
  • 12
    • 0024456866 scopus 로고
    • CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells
    • Davies A, Simmons DL, Hale G, Harrison RA, Tighe H, et al. (1989) CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. J Exp Med 170: 637-654.
    • (1989) J Exp Med , vol.170 , pp. 637-654
    • Davies, A.1    Simmons, D.L.2    Hale, G.3    Harrison, R.A.4    Tighe, H.5
  • 13
    • 0025233715 scopus 로고
    • The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9
    • Rollins SA, Sims PJ, (1990) The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. J Immunol 144: 3478-3483.
    • (1990) J Immunol , vol.144 , pp. 3478-3483
    • Rollins, S.A.1    Sims, P.J.2
  • 14
    • 0027441972 scopus 로고
    • Interactions of soluble CD59 with the terminal complement complexes. CD59 and C9 compete for a nascent epitope on C8
    • Lehto T, Meri S, (1993) Interactions of soluble CD59 with the terminal complement complexes. CD59 and C9 compete for a nascent epitope on C8. J Immunol 151: 4941-4949.
    • (1993) J Immunol , vol.151 , pp. 4941-4949
    • Lehto, T.1    Meri, S.2
  • 15
    • 0027936442 scopus 로고
    • Recombinant soluble CD59 inhibits reactive haemolysis with complement
    • Sugita Y, Ito K, Shiozuka K, Suzuki H, Gushima H, et al. (1994) Recombinant soluble CD59 inhibits reactive haemolysis with complement. Immunology 82: 34-41.
    • (1994) Immunology , vol.82 , pp. 34-41
    • Sugita, Y.1    Ito, K.2    Shiozuka, K.3    Suzuki, H.4    Gushima, H.5
  • 16
    • 0028086145 scopus 로고
    • High-density lipoproteins can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma
    • Vakeva A, Jauhiainen M, Ehnholm C, Lehto T, Meri S, (1994) High-density lipoproteins can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma. Immunology 82: 28-33.
    • (1994) Immunology , vol.82 , pp. 28-33
    • Vakeva, A.1    Jauhiainen, M.2    Ehnholm, C.3    Lehto, T.4    Meri, S.5
  • 17
    • 1542781737 scopus 로고    scopus 로고
    • Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo
    • Fraser DA, Harris CL, Williams AS, Mizuno M, Gallagher S, et al. (2003) Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo. J Biol Chem 278: 48921-48927.
    • (2003) J Biol Chem , vol.278 , pp. 48921-48927
    • Fraser, D.A.1    Harris, C.L.2    Williams, A.S.3    Mizuno, M.4    Gallagher, S.5
  • 18
    • 0034761870 scopus 로고    scopus 로고
    • Membrane complement regulators protect against the development of type II collagen-induced arthritis in rats
    • Mizuno M, Nishikawa K, Spiller OB, Morgan BP, Okada N, et al. (2001) Membrane complement regulators protect against the development of type II collagen-induced arthritis in rats. Arthritis Rheum 44: 2425-2434.
    • (2001) Arthritis Rheum , vol.44 , pp. 2425-2434
    • Mizuno, M.1    Nishikawa, K.2    Spiller, O.B.3    Morgan, B.P.4    Okada, N.5
  • 19
    • 77958590255 scopus 로고    scopus 로고
    • Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice
    • Bora NS, Jha P, Lyzogubov VV, Kaliappan S, Liu J, et al. (2010) Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice. J Biol Chem 285: 33826-33833.
    • (2010) J Biol Chem , vol.285 , pp. 33826-33833
    • Bora, N.S.1    Jha, P.2    Lyzogubov, V.V.3    Kaliappan, S.4    Liu, J.5
  • 20
    • 53149105921 scopus 로고    scopus 로고
    • Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE
    • Ramo K, Cashman SM, Kumar-Singh R, (2008) Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE. Invest Ophthalmol Vis Sci 49: 4126-4136.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4126-4136
    • Ramo, K.1    Cashman, S.M.2    Kumar-Singh, R.3
  • 21
    • 57049106918 scopus 로고    scopus 로고
    • Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors
    • Appledorn DM, McBride A, Seregin S, Scott JM, Schuldt N, et al. (2008) Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Ther 15: 1606-1617.
    • (2008) Gene Ther , vol.15 , pp. 1606-1617
    • Appledorn, D.M.1    McBride, A.2    Seregin, S.3    Scott, J.M.4    Schuldt, N.5
  • 22
    • 10344260641 scopus 로고    scopus 로고
    • Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies
    • Jiang H, Wang Z, Serra D, Frank MM, Amalfitano A, (2004) Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies. Mol Ther 10: 1140-1142.
    • (2004) Mol Ther , vol.10 , pp. 1140-1142
    • Jiang, H.1    Wang, Z.2    Serra, D.3    Frank, M.M.4    Amalfitano, A.5
  • 23
    • 79551622680 scopus 로고    scopus 로고
    • Preclinical Safety Evaluation of AAV2-sFLT01- A Gene Therapy for Age-related Macular Degeneration
    • Maclachlan TK, Lukason M, Collins M, Munger R, Isenberger E, et al. (2011) Preclinical Safety Evaluation of AAV2-sFLT01- A Gene Therapy for Age-related Macular Degeneration. Mol Ther 19 (2): 326-34.
    • (2011) Mol Ther , vol.19 , Issue.2 , pp. 326-334
    • Maclachlan, T.K.1    Lukason, M.2    Collins, M.3    Munger, R.4    Isenberger, E.5
  • 24
    • 36048937343 scopus 로고    scopus 로고
    • Complement-targeted therapeutics
    • Ricklin D, Lambris JD, (2007) Complement-targeted therapeutics. Nat Biotechnol 25: 1265-1275.
    • (2007) Nat Biotechnol , vol.25 , pp. 1265-1275
    • Ricklin, D.1    Lambris, J.D.2
  • 25
    • 0033056675 scopus 로고    scopus 로고
    • Assessment of complement deficiency in patients with meningococcal disease in The Netherlands
    • Fijen CA, Kuijper EJ, te Bulte MT, Daha MR, Dankert J, (1999) Assessment of complement deficiency in patients with meningococcal disease in The Netherlands. Clin Infect Dis 28: 98-105.
    • (1999) Clin Infect Dis , vol.28 , pp. 98-105
    • Fijen, C.A.1    Kuijper, E.J.2    te Bulte, M.T.3    Daha, M.R.4    Dankert, J.5
  • 26
    • 0031901920 scopus 로고    scopus 로고
    • Characterization of Neisseria meningitidis strains causing disease in complement-deficient and complement-sufficient patients
    • Fijen CA, Kuijper EJ, Dankert J, Daha MR, Caugant DA, (1998) Characterization of Neisseria meningitidis strains causing disease in complement-deficient and complement-sufficient patients. J Clin Microbiol 36: 2342-2345.
    • (1998) J Clin Microbiol , vol.36 , pp. 2342-2345
    • Fijen, C.A.1    Kuijper, E.J.2    Dankert, J.3    Daha, M.R.4    Caugant, D.A.5
  • 27
    • 0031008871 scopus 로고    scopus 로고
    • Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality
    • Homann C, Varming K, Hogasen K, Mollnes TE, Graudal N, et al. (1997) Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality. Gut 40: 544-549.
    • (1997) Gut , vol.40 , pp. 544-549
    • Homann, C.1    Varming, K.2    Hogasen, K.3    Mollnes, T.E.4    Graudal, N.5
  • 28
    • 77955883153 scopus 로고    scopus 로고
    • Complement: a key system for immune surveillance and homeostasis
    • Ricklin D, Hajishengallis G, Yang K, Lambris JD, (2010) Complement: a key system for immune surveillance and homeostasis. Nat Immunol 11: 785-797.
    • (2010) Nat Immunol , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 29
    • 79952115634 scopus 로고    scopus 로고
    • The role of the classical complement cascade in synapse loss during development and glaucoma
    • Rosen AM, Stevens B, (2010) The role of the classical complement cascade in synapse loss during development and glaucoma. Adv Exp Med Biol 703: 75-93.
    • (2010) Adv Exp Med Biol , vol.703 , pp. 75-93
    • Rosen, A.M.1    Stevens, B.2
  • 31
    • 0035818555 scopus 로고    scopus 로고
    • Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector
    • Kim IH, Jozkowicz A, Piedra PA, Oka K, Chan L, (2001) Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector. Proc Natl Acad Sci U S A 98: 13282-13287.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13282-13287
    • Kim, I.H.1    Jozkowicz, A.2    Piedra, P.A.3    Oka, K.4    Chan, L.5
  • 32
    • 58149484922 scopus 로고    scopus 로고
    • Ocular gene therapy: current progress and future prospects
    • Colella P, Cotugno G, Auricchio A, (2009) Ocular gene therapy: current progress and future prospects. Trends Mol Med 15: 23-31.
    • (2009) Trends Mol Med , vol.15 , pp. 23-31
    • Colella, P.1    Cotugno, G.2    Auricchio, A.3
  • 33
    • 33746909909 scopus 로고    scopus 로고
    • Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B
    • Jiang H, Pierce GF, Ozelo MC, de Paula EV, Vargas JA, et al. (2006) Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B. Mol Ther 14: 452-455.
    • (2006) Mol Ther , vol.14 , pp. 452-455
    • Jiang, H.1    Pierce, G.F.2    Ozelo, M.C.3    de Paula, E.V.4    Vargas, J.A.5
  • 34
    • 33748117817 scopus 로고    scopus 로고
    • Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD
    • Cashman SM, Bowman L, Christofferson J, Kumar-Singh R, (2006) Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD. Invest Ophthalmol Vis Sci 47: 3496-3504.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3496-3504
    • Cashman, S.M.1    Bowman, L.2    Christofferson, J.3    Kumar-Singh, R.4
  • 35
    • 34548061749 scopus 로고    scopus 로고
    • Improved Retinal Transduction In Vivo and Photoreceptor-specific Transgene Expression Using Adenovirus Vectors With Modified Penton Base
    • Cashman SM, McCullough L, Kumar-Singh R, (2007) Improved Retinal Transduction In Vivo and Photoreceptor-specific Transgene Expression Using Adenovirus Vectors With Modified Penton Base. Mol Ther 15: 1640-1646.
    • (2007) Mol Ther , vol.15 , pp. 1640-1646
    • Cashman, S.M.1    McCullough, L.2    Kumar-Singh, R.3
  • 36
    • 32944481724 scopus 로고    scopus 로고
    • Adenoviral Vector-Delivered Pigment Epithelium-Derived Factor for Neovascular Age-Related Macular Degeneration: Results of a Phase I Clinical Trial
    • Campochiaro PA, Dong Nguyen Q, Mahmood Shah S, Klein ML, Holz E, et al. (2006) Adenoviral Vector-Delivered Pigment Epithelium-Derived Factor for Neovascular Age-Related Macular Degeneration: Results of a Phase I Clinical Trial. Hum Gene Ther 17: 167-176.
    • (2006) Hum Gene Ther , vol.17 , pp. 167-176
    • Campochiaro, P.A.1    Dong Nguyen, Q.2    Mahmood Shah, S.3    Klein, M.L.4    Holz, E.5
  • 37
    • 31644447744 scopus 로고    scopus 로고
    • Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir
    • Chevez-Barrios P, Chintagumpala M, Mieler W, Paysse E, Boniuk M, et al. (2005) Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir. J Clin Oncol 23: 7927-7935.
    • (2005) J Clin Oncol , vol.23 , pp. 7927-7935
    • Chevez-Barrios, P.1    Chintagumpala, M.2    Mieler, W.3    Paysse, E.4    Boniuk, M.5
  • 38
    • 77957587385 scopus 로고    scopus 로고
    • Absence of systemic immune response to adenovectors after intraocular administration to children with retinoblastoma
    • Ildefonso CJ, Kong L, Leen A, Chai SJ, Petrochelli V, et al. Absence of systemic immune response to adenovectors after intraocular administration to children with retinoblastoma. Mol Ther 18: 1885-1890.
    • Mol Ther , vol.18 , pp. 1885-1890
    • Ildefonso, C.J.1    Kong, L.2    Leen, A.3    Chai, S.J.4    Petrochelli, V.5
  • 39
    • 0033659939 scopus 로고    scopus 로고
    • Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59
    • Sohn JH, Kaplan HJ, Suk HJ, Bora PS, Bora NS, (2000) Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59. Invest Ophthalmol Vis Sci 41: 4195-4202.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 4195-4202
    • Sohn, J.H.1    Kaplan, H.J.2    Suk, H.J.3    Bora, P.S.4    Bora, N.S.5
  • 40
    • 79551652669 scopus 로고    scopus 로고
    • Inhibition of Choroidal Neovascularization in a Nonhuman Primate Model by Intravitreal Administration of an AAV2 Vector Expressing a Novel Anti-VEGF Molecule
    • Lukason M, Dufresne E, Rubin H, Pechan P, Li Q, et al. (2011) Inhibition of Choroidal Neovascularization in a Nonhuman Primate Model by Intravitreal Administration of an AAV2 Vector Expressing a Novel Anti-VEGF Molecule. Mol Ther 19 (2): 260-5.
    • (2011) Mol Ther , vol.19 , Issue.2 , pp. 260-265
    • Lukason, M.1    Dufresne, E.2    Rubin, H.3    Pechan, P.4    Li, Q.5
  • 41
    • 0030024402 scopus 로고    scopus 로고
    • Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors
    • Fallaux FJ, Kranenburg O, Cramer SJ, Houweling A, Van Ormondt H, et al. (1996) Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors. HumGene Ther 7: 215-222.
    • (1996) HumGene Ther , vol.7 , pp. 215-222
    • Fallaux, F.J.1    Kranenburg, O.2    Cramer, S.J.3    Houweling, A.4    van Ormondt, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.