Genetics of age-related macular degeneration: Current concepts, future directions

Seminars in Ophthalmology

Volumn 26, Issue 3, 2011, Pages 77-93

  Deangelis, Margaret M ^a,b   Silveira, Alexandra C ^a   Carr, Elizabeth A ^b   Kim, Ivana K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

ARMS2 HTRA1; CFH; choroidal neovascularization; complement; geographic atrophy; susceptibility

Indexed keywords

ADENOSINE TRIPHOSPHATE BINDING CASSETTE TRANSPORTER SUBFAMILY A MEMBER 4 PROTEIN; AGE RELATED MACULOPATHY SUSCEPTIBILITY 2 PROTEIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; ARYLDIALKYLPHOSPHATASE 1; CHEMOKINE RECEPTOR CX3CR1; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; CX3C CHEMOKINE; CYSTATIN C; ELONGATION OF VERY LONG CHAIN FATTY ACID; FIBULIN 5; HEMICENTIN 1; HTRA SERINE PEPTIDASE 1; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PEPTIDES AND PROTEINS; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING FAMILY A MEMBER 1 PROTEIN; SYNAPSIN 3; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VERY LONG CHAIN FATTY ACID; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

3' UNTRANSLATED REGION; AGE; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CHOROID CAPILLARY LAYER; CHROMOSOME 10; CHROMOSOME 10Q; CHROMOSOME 12P; CHROMOSOME 12Q; CHROMOSOME 14Q; CHROMOSOME 15Q; CHROMOSOME 16P; CHROMOSOME 17Q; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME 1Q; CHROMOSOME 21Q; CHROMOSOME 22Q; CHROMOSOME 2P; CHROMOSOME 5Q; CHROMOSOME 6Q; CHROMOSOME 9Q; CIGARETTE SMOKING; COPY NUMBER VARIATION; CYTOSOL; DISEASE COURSE; DISEASE SEVERITY; DRUSEN; EXON; GENE DELETION; GENE EXPRESSION; GENE INTERACTION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GEOGRAPHIC ATROPHY; HUMAN; HUMAN GENOME; HYPERTENSION; INDEL MUTATION; INTRON; KNOCKOUT MOUSE; LIPID TRANSPORT; MICROARRAY ANALYSIS; MICROSATELLITE MARKER; MITOCHONDRIAL TARGETING SIGNAL; NONHUMAN; PATHOGENESIS; PHOTORECEPTOR; PIGMENT EPITHELIUM; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROTEOMICS; RETINA; RETINA MACULA AGE RELATED DEGENERATION; RISK FACTOR; SHORT TANDEM REPEAT; SINGLE NUCLEOTIDE POLYMORPHISM; SUBRETINAL NEOVASCULARIZATION;

CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 10; COMPLEMENT FACTOR H; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACULAR DEGENERATION; MEMBRANE PROTEINS; PROTEINS; SERINE ENDOPEPTIDASES;

EID: 79957604976     PISSN: 08820538     EISSN: 17445205     Source Type: Journal    
DOI: 10.3109/08820538.2011.577129     Document Type: Article

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