메뉴 건너뛰기




Volumn 145, Issue 4, 2008, Pages

Pigment Epithelium-Derived Factor Gene Met72Thr Polymorphism Is Associated With Increased Risk of Wet Age-related Macular Degeneration

Author keywords

[No Author keywords available]

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR;

EID: 40849135678     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2007.11.006     Document Type: Article
Times cited : (32)

References (51)
  • 1
    • 0038748022 scopus 로고    scopus 로고
    • The Bowman lecture: towards an understanding of age-related macular disease
    • Bird A.C. The Bowman lecture: towards an understanding of age-related macular disease. Eye 17 (2003) 457-466
    • (2003) Eye , vol.17 , pp. 457-466
    • Bird, A.C.1
  • 2
    • 1842530296 scopus 로고    scopus 로고
    • Causes and prevalence of visual impairment among adults in the United States
    • Congdon N., O'Colmain B.J., Klaver C.C., et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol 122 (2004) 477-485
    • (2004) Arch Ophthalmol , vol.122 , pp. 477-485
    • Congdon, N.1    O'Colmain, B.J.2    Klaver, C.C.3
  • 3
    • 11144354339 scopus 로고    scopus 로고
    • Prevalence of age-related macular degeneration in the United States
    • Friedman D.S., O'Colmain B.J., Munoz B., et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 122 (2004) 564-572
    • (2004) Arch Ophthalmol , vol.122 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Munoz, B.3
  • 4
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein R.J., Zeiss C., Chew E.Y., et al. Complement factor H polymorphism in age-related macular degeneration. Science 308 (2005) 385-389
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 5
    • 33644872864 scopus 로고    scopus 로고
    • Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers
    • Sepp T., Khan J.C., Thurlby D.A., et al. Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers. Invest Ophthalmol Vis Sci 47 (2006) 536-540
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 536-540
    • Sepp, T.1    Khan, J.C.2    Thurlby, D.A.3
  • 6
    • 33748106362 scopus 로고    scopus 로고
    • Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients
    • Lau L.I., Chen S.J., Cheng C.Y., et al. Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients. Invest Ophthalmol Vis Sci 47 (2006) 3242-3246
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3242-3246
    • Lau, L.I.1    Chen, S.J.2    Cheng, C.Y.3
  • 7
    • 34347244210 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Narayanan R., Butani V., Boyer D.S., et al. Complement factor H polymorphism in age-related macular degeneration. Ophthalmology 114 (2007) 1327-1331
    • (2007) Ophthalmology , vol.114 , pp. 1327-1331
    • Narayanan, R.1    Butani, V.2    Boyer, D.S.3
  • 8
    • 33751011889 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism in wet age-related macular degeneration
    • DeWan A., Liu M., Hartman S., et al. HTRA1 promoter polymorphism in wet age-related macular degeneration. Science 314 (2006) 989-992
    • (2006) Science , vol.314 , pp. 989-992
    • DeWan, A.1    Liu, M.2    Hartman, S.3
  • 9
    • 33751004690 scopus 로고    scopus 로고
    • A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
    • Yang Z., Camp N.J., Sun H., et al. A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 314 (2006) 992-993
    • (2006) Science , vol.314 , pp. 992-993
    • Yang, Z.1    Camp, N.J.2    Sun, H.3
  • 10
    • 34047270761 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration
    • Yoshida T., DeWan A., Zhang H., et al. HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration. Mol Vis 13 (2007) 545-548
    • (2007) Mol Vis , vol.13 , pp. 545-548
    • Yoshida, T.1    DeWan, A.2    Zhang, H.3
  • 11
    • 33845536782 scopus 로고    scopus 로고
    • Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy
    • Zhang S.X., and Ma J.X. Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy. Prog Retin Eye Res 26 (2007) 1-37
    • (2007) Prog Retin Eye Res , vol.26 , pp. 1-37
    • Zhang, S.X.1    Ma, J.X.2
  • 12
    • 0036329579 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration
    • Holekamp N.M., Bouck N., and Volpert O. Pigment epithelium-derived factor is deficient in the vitreous of patients with choroidal neovascularization due to age-related macular degeneration. Am J Ophthalmol 134 (2002) 220-227
    • (2002) Am J Ophthalmol , vol.134 , pp. 220-227
    • Holekamp, N.M.1    Bouck, N.2    Volpert, O.3
  • 13
    • 30344447284 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration
    • Bhutto I.A., McLeod D.S., Hasegawa T., et al. Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration. Exp Eye Res 82 (2006) 99-110
    • (2006) Exp Eye Res , vol.82 , pp. 99-110
    • Bhutto, I.A.1    McLeod, D.S.2    Hasegawa, T.3
  • 14
    • 33644893607 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor
    • Zhang S.X., Wang J.J., Gao G., Shao C., Mott R., and Ma J.X. Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor. FASEB J 20 (2006) 323-325
    • (2006) FASEB J , vol.20 , pp. 323-325
    • Zhang, S.X.1    Wang, J.J.2    Gao, G.3    Shao, C.4    Mott, R.5    Ma, J.X.6
  • 15
    • 0035956869 scopus 로고    scopus 로고
    • Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor
    • Stellmach V., Crawford S.E., Zhou W., and Bouck N. Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor. Proc Natl Acad Sci U S A 98 (2001) 2593-2597
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2593-2597
    • Stellmach, V.1    Crawford, S.E.2    Zhou, W.3    Bouck, N.4
  • 16
    • 20844447893 scopus 로고    scopus 로고
    • Periocular gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization in a human-sized eye
    • Saishin Y., Silva R.L., Saishin Y., et al. Periocular gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization in a human-sized eye. Hum Gene Ther 16 (2005) 473-478
    • (2005) Hum Gene Ther , vol.16 , pp. 473-478
    • Saishin, Y.1    Silva, R.L.2    Saishin, Y.3
  • 17
    • 0034945843 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization
    • Mori K., Duh E., Gehlbach P., et al. Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. J Cell Physiol 188 (2001) 253-263
    • (2001) J Cell Physiol , vol.188 , pp. 253-263
    • Mori, K.1    Duh, E.2    Gehlbach, P.3
  • 18
    • 0036297886 scopus 로고    scopus 로고
    • Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor
    • Mori K., Gehlbach P., Ando A., et al. Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci 43 (2002) 2428-2434
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 2428-2434
    • Mori, K.1    Gehlbach, P.2    Ando, A.3
  • 19
    • 0036271989 scopus 로고    scopus 로고
    • AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization
    • Mori K., Gehlbach P., Yamamoto S., et al. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci 43 (2002) 1994-2000
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1994-2000
    • Mori, K.1    Gehlbach, P.2    Yamamoto, S.3
  • 20
    • 2342507629 scopus 로고    scopus 로고
    • Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site
    • Liu H., Ren J.G., Cooper W.L., Hawkins C.E., Cowan M.R., and Tong P.Y. Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site. Proc Natl Acad Sci U S A 101 (2004) 6605-6610
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6605-6610
    • Liu, H.1    Ren, J.G.2    Cooper, W.L.3    Hawkins, C.E.4    Cowan, M.R.5    Tong, P.Y.6
  • 21
    • 32944481724 scopus 로고    scopus 로고
    • Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: results of a phase I clinical trial
    • Campochiaro P.A., Nguyen Q.D., Shah S.M., et al. Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: results of a phase I clinical trial. Hum Gene Ther 17 (2006) 167-176
    • (2006) Hum Gene Ther , vol.17 , pp. 167-176
    • Campochiaro, P.A.1    Nguyen, Q.D.2    Shah, S.M.3
  • 22
    • 33947243060 scopus 로고    scopus 로고
    • Four polymorphic variations in the PEDF gene identified during the mutation screening of patients with Leber congenital amaurosis
    • Koenekoop R., Pina A.L., Loyer M., et al. Four polymorphic variations in the PEDF gene identified during the mutation screening of patients with Leber congenital amaurosis. Mol Vis 5 (1999) 10
    • (1999) Mol Vis , vol.5 , pp. 10
    • Koenekoop, R.1    Pina, A.L.2    Loyer, M.3
  • 23
    • 0038715435 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor Met72Thr polymorphism in patients with diabetic microangiopathy
    • Yamagishi S., Amano S., Inagaki Y., et al. Pigment epithelium-derived factor Met72Thr polymorphism in patients with diabetic microangiopathy. Int J Clin Pharmacol Res 22 (2002) 67-71
    • (2002) Int J Clin Pharmacol Res , vol.22 , pp. 67-71
    • Yamagishi, S.1    Amano, S.2    Inagaki, Y.3
  • 24
    • 17044428933 scopus 로고    scopus 로고
    • Met72Thr polymorphism of pigment epithelium-derived factor gene and susceptibility to age-related macular degeneration
    • Yamagishi S., Nakamura K., Inoue H., and Takeuchi M. Met72Thr polymorphism of pigment epithelium-derived factor gene and susceptibility to age-related macular degeneration. Med Hypotheses 64 (2005) 1202-1204
    • (2005) Med Hypotheses , vol.64 , pp. 1202-1204
    • Yamagishi, S.1    Nakamura, K.2    Inoue, H.3    Takeuchi, M.4
  • 25
    • 0028934221 scopus 로고
    • An international classification and grading system for age-related maculopathy and age-related macular degeneration. The international ARM Epidemiological Study Group
    • Bird A.C., Bressler N.M., Bressler S.B., et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The international ARM Epidemiological Study Group. Surv Ophthalmol 39 (1995) 367-374
    • (1995) Surv Ophthalmol , vol.39 , pp. 367-374
    • Bird, A.C.1    Bressler, N.M.2    Bressler, S.B.3
  • 26
    • 33745013336 scopus 로고    scopus 로고
    • Consequences of verteporfin photodynamic therapy on choroidal neovascular membranes
    • 2
    • Tatar O., Kaiserling E., Adam A., et al. Consequences of verteporfin photodynamic therapy on choroidal neovascular membranes. Arch Ophthalmol 124 (2006) 815-823 2
    • (2006) Arch Ophthalmol , vol.124 , pp. 815-823
    • Tatar, O.1    Kaiserling, E.2    Adam, A.3
  • 27
    • 0029879849 scopus 로고    scopus 로고
    • Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes
    • Lopez P.F., Sippy B.D., Lambert H.M., Thach A.B., and Hinton D.R. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Invest Ophthalmol Vis Sci 37 (1996) 855-868
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 855-868
    • Lopez, P.F.1    Sippy, B.D.2    Lambert, H.M.3    Thach, A.B.4    Hinton, D.R.5
  • 28
    • 0029831672 scopus 로고    scopus 로고
    • Subfoveal fibrovascular membranes in age-related macular degeneration expresses vascular endothelial growth factor
    • Kvanta A., Algvere P.V., Berglin L., and Seregard S. Subfoveal fibrovascular membranes in age-related macular degeneration expresses vascular endothelial growth factor. Invest Ophthalmol Vis Sci 37 (1996) 1929-1934
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1929-1934
    • Kvanta, A.1    Algvere, P.V.2    Berglin, L.3    Seregard, S.4
  • 29
    • 0028037723 scopus 로고
    • Growth factor localization in choroidal neovascular membranes of age-related macular degeneration
    • Amin R., Puklin J.E., and Frank R.N. Growth factor localization in choroidal neovascular membranes of age-related macular degeneration. Invest Ophthalmol Vis Sci 35 (1994) 3178-3188
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3178-3188
    • Amin, R.1    Puklin, J.E.2    Frank, R.N.3
  • 30
    • 0035087499 scopus 로고    scopus 로고
    • Age-related macular degeneration is associated with increased vascular endothelial growth factor, hemorheology and endothelial dysfunction
    • Lip P.L., Blann A.D., Hope-Ross M., Gibson J.M., and Lip G.Y. Age-related macular degeneration is associated with increased vascular endothelial growth factor, hemorheology and endothelial dysfunction. Ophthalmology 108 (2001) 705-710
    • (2001) Ophthalmology , vol.108 , pp. 705-710
    • Lip, P.L.1    Blann, A.D.2    Hope-Ross, M.3    Gibson, J.M.4    Lip, G.Y.5
  • 31
    • 0029935043 scopus 로고    scopus 로고
    • Levels of vascular endothelial growth factor are elevated in the vitreous of patients with subretinal neovascularization
    • Wells J.A., Murthy R., Chibber R., et al. Levels of vascular endothelial growth factor are elevated in the vitreous of patients with subretinal neovascularization. Br J Ophthalmol 80 (1996) 363-366
    • (1996) Br J Ophthalmol , vol.80 , pp. 363-366
    • Wells, J.A.1    Murthy, R.2    Chibber, R.3
  • 32
    • 0031050126 scopus 로고    scopus 로고
    • Increased expression of angiogenic growth factors in age-related maculopathy
    • Kliffen M., Sharma H.S., Mooy C.M., Kerkvliet S., and de Jong P.T. Increased expression of angiogenic growth factors in age-related maculopathy. Br J Ophthalmol 81 (1997) 154-162
    • (1997) Br J Ophthalmol , vol.81 , pp. 154-162
    • Kliffen, M.1    Sharma, H.S.2    Mooy, C.M.3    Kerkvliet, S.4    de Jong, P.T.5
  • 33
    • 0029025831 scopus 로고
    • Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity
    • Tombran-Tink J., Shivaram S.M., Chader G.J., Johnson L.V., and Bok D. Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci 15 (1995) 4992-5003
    • (1995) J Neurosci , vol.15 , pp. 4992-5003
    • Tombran-Tink, J.1    Shivaram, S.M.2    Chader, G.J.3    Johnson, L.V.4    Bok, D.5
  • 34
    • 0036235046 scopus 로고    scopus 로고
    • Expression of pigment epithelium-derived factor in experimental choroidal neovascularization
    • Renno R.Z., Youssri A.I., Michaud N., Gragoudas E.S., and Miller J.W. Expression of pigment epithelium-derived factor in experimental choroidal neovascularization. Invest Ophthalmol Vis Sci 43 (2002) 1574-1580
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1574-1580
    • Renno, R.Z.1    Youssri, A.I.2    Michaud, N.3    Gragoudas, E.S.4    Miller, J.W.5
  • 35
    • 2442453475 scopus 로고    scopus 로고
    • Differential expression of angioregulatory factors in normal and CNV-derived human retinal pigment epithelium
    • Martin G., Schlunck G., Hansen L.L., and Agostini H.T. Differential expression of angioregulatory factors in normal and CNV-derived human retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol 242 (2004) 321-326
    • (2004) Graefes Arch Clin Exp Ophthalmol , vol.242 , pp. 321-326
    • Martin, G.1    Schlunck, G.2    Hansen, L.L.3    Agostini, H.T.4
  • 36
    • 0024394207 scopus 로고
    • Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells
    • Tombran-Tink J., and Johnson L.V. Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells. Invest Ophthalmol Vis Sci 30 (1989) 1700-1707
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , pp. 1700-1707
    • Tombran-Tink, J.1    Johnson, L.V.2
  • 37
  • 38
    • 0028803776 scopus 로고
    • Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop
    • Becerra S.P., Sagasti A., Spinella P., and Notario V. Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop. J Biol Chem 270 (1995) 25992-25999
    • (1995) J Biol Chem , vol.270 , pp. 25992-25999
    • Becerra, S.P.1    Sagasti, A.2    Spinella, P.3    Notario, V.4
  • 39
    • 0031455819 scopus 로고    scopus 로고
    • Structure-function studies on PEDF. A noninhibitory serpin with neurotrophic activity
    • Becerra S.P. Structure-function studies on PEDF. A noninhibitory serpin with neurotrophic activity. Adv Exp Med Biol 425 (1997) 223-237
    • (1997) Adv Exp Med Biol , vol.425 , pp. 223-237
    • Becerra, S.P.1
  • 40
    • 0032125517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death
    • Araki T., Taniwaki T., Becerra S.P., Chader G.J., and Schwartz J.P. Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death. J Neurosci Res 53 (1998) 7-15
    • (1998) J Neurosci Res , vol.53 , pp. 7-15
    • Araki, T.1    Taniwaki, T.2    Becerra, S.P.3    Chader, G.J.4    Schwartz, J.P.5
  • 41
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: a potent inhibitor of angiogenesis
    • Dawson D.W., Volpert O.V., Gillis P., et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 285 (1999) 245-248
    • (1999) Science , vol.285 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3
  • 42
    • 0035793436 scopus 로고    scopus 로고
    • Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularization
    • Gao G., Li Y., Zhang D., Gee S., Crosson C., and Ma J. Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularization. FEBS Lett 489 (2001) 270-276
    • (2001) FEBS Lett , vol.489 , pp. 270-276
    • Gao, G.1    Li, Y.2    Zhang, D.3    Gee, S.4    Crosson, C.5    Ma, J.6
  • 43
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • Volpert O.V., Zaichuk T., Zhou W., et al. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 8 (2002) 349-357
    • (2002) Nat Med , vol.8 , pp. 349-357
    • Volpert, O.V.1    Zaichuk, T.2    Zhou, W.3
  • 44
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • de Jong P.T. Age-related macular degeneration. N Engl J Med 355 (2006) 1474-1485
    • (2006) N Engl J Med , vol.355 , pp. 1474-1485
    • de Jong, P.T.1
  • 45
    • 33747873216 scopus 로고    scopus 로고
    • Complement factor H increases risk for atrophic age-related macular degeneration
    • Postel E.A., Agarwal A., Caldwell J., et al. Complement factor H increases risk for atrophic age-related macular degeneration. Ophthalmology 113 (2006) 1504-1507
    • (2006) Ophthalmology , vol.113 , pp. 1504-1507
    • Postel, E.A.1    Agarwal, A.2    Caldwell, J.3
  • 46
    • 22844438080 scopus 로고    scopus 로고
    • Recurrence of retinal pigment epithelial changes after macular translocation with 360 degrees peripheral retinectomy for geographic atrophy
    • Cahill M.T., Mruthyunjaya P., Bowes-Rickman C., and Toth C.A. Recurrence of retinal pigment epithelial changes after macular translocation with 360 degrees peripheral retinectomy for geographic atrophy. Arch Ophthalmol 123 (2005) 935-938
    • (2005) Arch Ophthalmol , vol.123 , pp. 935-938
    • Cahill, M.T.1    Mruthyunjaya, P.2    Bowes-Rickman, C.3    Toth, C.A.4
  • 47
    • 0036875316 scopus 로고    scopus 로고
    • The role of apoptosis in age-related macular degeneration
    • Dunaief J.L., Dentchev T., Ying G.S., and Milam A.H. The role of apoptosis in age-related macular degeneration. Arch Ophthalmol 120 (2002) 1435-1442
    • (2002) Arch Ophthalmol , vol.120 , pp. 1435-1442
    • Dunaief, J.L.1    Dentchev, T.2    Ying, G.S.3    Milam, A.H.4
  • 48
    • 34548749902 scopus 로고    scopus 로고
    • LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population
    • Kondo N., Honda S., Ishibashi K., Tsukahara Y., and Negi A. LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population. Am J Ophthalmol 144 (2007) 608-612
    • (2007) Am J Ophthalmol , vol.144 , pp. 608-612
    • Kondo, N.1    Honda, S.2    Ishibashi, K.3    Tsukahara, Y.4    Negi, A.5
  • 49
    • 36049042661 scopus 로고    scopus 로고
    • A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
    • Kanda A., Chen W., Othman M., et al. A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci U S A 104 (2007) 16227-16232
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16227-16232
    • Kanda, A.1    Chen, W.2    Othman, M.3
  • 51
    • 0035173448 scopus 로고    scopus 로고
    • Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF
    • Ohno-Matsui K., Morita I., Tombran-Tink J., et al. Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF. J Cell Physiol 189 (2001) 323-333
    • (2001) J Cell Physiol , vol.189 , pp. 323-333
    • Ohno-Matsui, K.1    Morita, I.2    Tombran-Tink, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.