Hydrodynamics of ageing Bruch's membrane: Implications for macular disease

Experimental Eye Research

Volumn 62, Issue 5, 1996, Pages 565-572

  Starita, Carla ^a,b   Hussain, Ali A ^a   Pagliarini, Sergio ^a   Marshall, John ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Age related macular degeneration; Ageing; Bruch's membrane; Drusen; Hydraulic conductivity

Indexed keywords

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; BRUCH MEMBRANE; FEMALE; HUMAN; HUMAN TISSUE; HYDRODYNAMICS; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; WATER TRANSPORT;

EID: 0029950660     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1996.0066     Document Type: Article

References (17)

1. Bird, A. C. and Marshall, J. (1986). Retinal pigment epithelial detachments in the elderly. Trans. Ophthalmol. Soc. U.K. 105, 674-682.
2. Bok, D. (1985). Retinal photoreceptor-pigment epithelium interactions. Invest. Ophthalmol. Vis. Sci. 26, 169.
3. Burns, R. P. and Feeney-Burns, L. (1980). Clinico-morphological correlations of drusen and Bruch's membrane. Trans. Am. Ophthalmol. Soc. 78, 206.
4. Feeney-Burns, L. and Ellersieck, M. R. (1985). Age-related changes in the ultrastructure of Bruch's membrane. Am. J. Ophthalmol. 100, 686-97.
5. Fisher, R. F. (1987). The influence of age on some ocular basement membranes. Eye 1, 184-9.
6. Green, W. R., Key, S. N. (1977). Senile macular degeneration: a histopathological study. Trans. Am. Ophthalmol. Soc. 75, 180-250.
7. Green, W. R., Enger, C. (1992). Age-related macular degeneration: histopathological studies. Ophthalmology 100, 1519-35.
8. Grindle, C. M. J. and Marshall, J. (1978). Ageing changes in Bruch's membrane and their functional implications. Trans. Ophthalmol. Soc. U.K. 98, 172-5.
9. Hogan, M. J. and Alvarado, J. (1967). Studies on the human macula: IV. Aging changes in Bruch's membrane. Arch. Ophthalmol. 77, 410-20.
10. Holz, F. G., Sheraidah, G. S., Pauleikhoff, D. and Bird, A. C. (1994). Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane. Arch. Ophthalmol. 112, 402-6.
11. Killings worth, M. C. (1987). Age-related components of Bruch's membrane in the human eye. Graefe's Arch. Clin. Exp. Ophthalmol. 225, 406-12.
12. Moore, D., Hussain, A. A. and Marshall, J. (1995). Age-related variation in the hydraulic conductivity of Bruch's membrane. Invest. Ophthalmol. Vis. Sci. 36, 1290-7.
13. Pauleikhoff, D., Harper, A., Marshall, J. and Bird, A. C. (1989). Aging changes in Bruch's membrane: a histochemical and morphological study. Ophthalmology 97, 171-7.
14. Ramrattan, R. S., Van der Schaft, T. L., Mooy, C. L., de Bruijn, W. C., Mulder, P. G. H. and de Jong, P. T. V. M. (1994). Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging. Invest. Ophthalmol. Vis. Sci. 35, 2857-64.
15. Sarks, S. H. (1976). Ageing and degeneration in the macular region: a clinico-pathological study. Br. J. Ophthalmol. 60, 324-41.
16. Sheraidah, G., Steinmetz, R., Maguire, J., Pauleikhoff, D., Marshall, J. and Bird, A. C. (1993). Correlation between lipids extracted from Bruch's membrane and age. Ophthalmology 100, 47-51.
17. Young, R.W. (1987). Pathophysiology of age related macular degeneration. Surv. Ophthalmol. 31, 291-306.