An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

Progress in Retinal and Eye Research

Volumn 20, Issue 6, 2001, Pages 705-732

  Hageman, Gregory S ^a   Luthert, Phil J ^b   Victor Chong, N H ^a,b   Johnson, Lincoln V ^c   Anderson, Don H ^c   Mullins, Robert F ^a  

^a UNIVERSITY OF IOWA   (United States)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID A PROTEIN; AMYLOID BETA PROTEIN; AMYLOID P COMPONENT; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR 10; CD83 ANTIGEN; CD86 ANTIGEN; CHONDROITIN SULFATE; FIBRINOGEN; GLUCOSE; GLYCOLIPID; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HLA DR ANTIGEN; IMMUNOGLOBULIN; INTEGRIN; MANNOSE; N ACETYLGLUCOSAMINE; PROTHROMBIN; SIALIC ACID; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UBIQUITIN; VITRONECTIN;

AGING; ANGIOGRAPHY; ANTIGEN PRESENTING CELL; ARTICLE; BIOCHEMISTRY; BIOGENESIS; BRUCH MEMBRANE; CARBOHYDRATE ANALYSIS; CELLULAR PARAMETERS; CHOROID PLEXUS; CYTOCHEMISTRY; DENDRITIC CELL; DRUSEN; GENOTYPE; HISTOCHEMISTRY; HUMAN; IMMUNE MEDIATED INJURY; INFLAMMATION; LIPID COMPOSITION; MOLECULAR BIOLOGY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; RETINA MACULA AGE RELATED DEGENERATION; RISK FACTOR;

EID: 0034832029     PISSN: 13509462     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1350-9462(01)00010-6     Document Type: Review

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