Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications

Annals of Medicine

Volumn 38, Issue 8, 2006, Pages 592-604

  Hageman, Gregory S ^a,b   Hancox, Lisa S ^a   Taiber, Andrew J ^a   Gehrs, Karen M ^a   Anderson, Don H ^b   Johnson, Lincoln V ^b   Radeke, Monte J ^b   Kavanagh, David ^c   Richards, Anna ^c   Atkinson, John ^c   Meri, Seppo ^d   Bergeron, Julie ^e   Zernant, Jana ^g   Merriam, Joanna ^g   Gold, Bert ^f   Allikmets, Rando ^g,h   Dean, Michael ^f   Hageman, Jill ^a   Hoballah, Jamal ^a   Stockman, Heather ^a   Immonen, Ilkka ^d   Laine, Matti ^d   Jarva, Hanna ^d   Järvelä, Irma ^d   Seitsonen, Sanna ^d   Barile, Gaetano ^e   Chang, Stanley ^e   Merriam, John C ^e   Smith, R Theodore ^e   Yannuzzi, Lawrence A ^e   more..

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF HELSINKI   (Finland)

^e SAIC FREDERICK INC   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g Och Spine at New York Presbyterian Hospitals   (United States)

^h NewYork Presbyterian Hospital   (United States)

Author keywords

Age related macular degeneration; Alternative pathway; Complement; Deletion; Evolution; Factor H; Factor H related; Haplotype; Vision

Indexed keywords

COMPLEMENT FACTOR H;

ALLELE; ARTICLE; CHOROID; COMPLEMENT FACTOR H RELATED GENE 1; COMPLEMENT FACTOR H RELATED GENE 3; CONTROLLED STUDY; ETHNIC DIFFERENCE; ETHNIC GROUP; EVOLUTION; GENE; GENE DELETION; GENE LOCUS; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HOMOZYGOTE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; LIVER; MAJOR CLINICAL STUDY; MULTIGENE FAMILY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION;

BLOTTING, WESTERN; CASE-CONTROL STUDIES; COHORT STUDIES; COMPLEMENT FACTOR H; CONTINENTAL POPULATION GROUPS; GENE DELETION; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HOMOZYGOTE; HUMANS; MACULAR DEGENERATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 33847153137     PISSN: 07853890     EISSN: 16512219     Source Type: Journal    
DOI: 10.1080/07853890601097030     Document Type: Article

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