Dietary antioxidants and primary prevention of age related macular degeneration: Systematic review and meta-analysis

British Medical Journal

Volumn 335, Issue 7623, 2007, Pages 755-759

  Chong, Elaine W T ^a   Wong, Tien Y ^a   Kreis, Andreas J ^a   Simpson, Julie A ^a   Guymer, Robyn H ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CAROTENE; ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; BETA CRYPTOXANTHIN; LYCOPENE; PLACEBO; RETINOL; XANTHOPHYLL; ZEAXANTHIN; ZINC;

ANTIOXIDANT ACTIVITY; ARTICLE; CATARACT; CLINICAL FEATURE; CLINICAL TRIAL; DIET SUPPLEMENTATION; DIETARY INTAKE; DISEASE COURSE; DRUG ACTIVITY; DRUG EFFECT; FOLLOW UP; HUMAN; META ANALYSIS; NUTRITIONAL ASSESSMENT; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROPHYLAXIS; QUESTIONNAIRE; RETINA MACULA AGE RELATED DEGENERATION; SYMPTOM; SYSTEMATIC REVIEW; VITAMIN SUPPLEMENTATION;

ANTIOXIDANTS; COHORT STUDIES; HUMANS; MACULAR DEGENERATION; PROSPECTIVE STUDIES; RANDOMIZED CONTROLLED TRIALS; TREATMENT FAILURE;

EID: 35348966298     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.39350.500428.47     Document Type: Article

References (29)

1. Arroyo JG. A 76-year-old man with macular degeneration. JAMA 2006;295:2394-406.
2. Chakravarthy U. Age related macular degeneration. BMJ 2006;333:869-70.
3. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, et al. Complement factor H variant increases the risk of age-related macular degeneration. Science 2005;308:419-21.
4. Baird PN, Richardson AJ, Robman LD, Dimitrov PN, Tikellis G, McCarty CA, et al. Apolipoprotein (APOE) gene is associated with progression of age-related macular degeneration (AMD). Hum Mutat 2006;27:337-42.
5. Thornton J, Edwards R, Mitchell P, Harrison RA, Buchan I, Kelly SP. Smoking and age-related macular degeneration: a review of association. Eye 2005;19:935-44.
6. Christen WG, Glynn RJ, Manson JE, Ajani UA, Buring JE. A prospective study of cigarette smoking and risk of age-related macular degeneration in men. JAMA 1996;276:1147-51.
7. Seddon JM, Willett WC, Speizer FE, Hankinson SE. A prospective study of cigarette smoking and age-related macular degeneration in women. JAMA 1996;276:1141-6.
8. Kelly SP, Thornton J, Lyratzopoulos G, Edwards R, Mitchell P. Smoking and blindness. BMJ 2004;328:537-8.
9. Eter N, Krohne TU, Holz FG. New pharmacologic approaches to therapy for age-related macular degeneration. BioDrugs 2006;20:167-79.
10. Gragoudas ES, Adamis AP, Cunningham ET Jr, Feinsod M, Guyer DR. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 2004;351:2805-16.
11. Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355:1419-31.
12. Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim RY, et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 2006;355:1432-44.
13. Jampol LM, Ferris FL 3rd. Antioxidants and zinc to prevent progression of age-related macular degeneration. JAMA 2001;286:2466-8.
14. Seddon JM, Hennekens CH. Vitamins, minerals, and macular degeneration: promising but unproven hypotheses. Arch Ophthalmol 1994;112:176-9.
15. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report No 8. Arch Ophthalmol 2001;119:1417-36.
16. Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. JAMA 1994;272:1413-20.
17. National Institutes of Health. Clinical Trials Database. http://clinicaltrials.gov (accessed November 2006)
18. Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health 1998;52:377-84.
19. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000;283:2008-12.
20. Deeks JJ, Dinnes J, D'Amico R, Sowden AJ, Sakarovitch C, Song F, et al. Evaluating non-randomised intervention studies. Health Technol Assess 2003;7:iii-x, 1-173.
21. Clarke M. The QUORUM statement. Lancet 2000;355:756-7.
22. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327:557-60.
23. Sterne JA, Egger M. Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol 2001;54:1046-55.
24. Egger M, Davey Smith G, Schneider M, Minder C. Bias in metaanalysis detected by a simple, graphical test. BMJ 1997;315:629-34.
25. Britton G. Structure and properties of carotenoids in relation to function. Faseb J 1995;9:1551-8.
26. Evans JR. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane Database Syst Rev 2006;(4):CD000254.
27. Egger M, Zellweger-Zahner T, Schneider M, Junker C, Lengeler C, Antes G. Language bias in randomised controlled trials published in English and German. Lancet 1997;350:326-9.
28. Moher D, Fortin P, Jadad AR, Juni P, Klassen T, Le Lorier J, et al. Completeness of reporting of trials published in languages other than English: implications for conduct and reporting of systematic reviews. Lancet 1996;347:363-6.
29. Egger M, Schneider M, Davey Smith G. Spurious precision? Metaanalysis of observational studies. BMJ 1998;316:140-4.