-
3
-
-
14944364782
-
The US twin study of age-related macular degeneration: Relative roles of geneticand environmental influences
-
Seddon JM, Cote J, Page WF, Aggen SH, Neale MC. The US twin study of age-related macular degeneration: relative roles of geneticand environmental influences. Arch Ophthalmol. 2005;123:321-327.
-
(2005)
Arch Ophthalmol.
, vol.123
, pp. 321-327
-
-
Seddon, J.M.1
Cote, J.2
Page, W.F.3
Aggen, S.H.4
Neale, M.C.5
-
4
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
Haines JL, Hauser MA, Schmidt S, et al. Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005;308:419-421.
-
(2005)
Science.
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
-
5
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
Hageman GS, Anderson DH, Johnson LV, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005;102:7227-7232.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
-
6
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science. 2005;308: 385-389.
-
(2005)
Science.
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
-
7
-
-
27744462212
-
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
-
Rivera A, Fisher SA, Fritsche LG, et al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet. 2005;14:3227-3236.
-
(2005)
Hum Mol Genet.
, vol.14
, pp. 3227-3236
-
-
Rivera, A.1
Fisher, S.A.2
Fritsche, L.G.3
-
8
-
-
33751004690
-
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
-
Yang Z, Camp NJ, Sun H, et al. A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science. 2006;314:992-993.
-
(2006)
Science.
, vol.314
, pp. 992-993
-
-
Yang, Z.1
Camp, N.J.2
Sun, H.3
-
9
-
-
33751011889
-
HTRA1 promoter polymorphism in wet age-related macular degeneration
-
Dewan A, Liu M, Hartman S, et al. HTRA1 promoter polymorphism in wet age-related macular degeneration. Science. 2006;314:989-992.
-
(2006)
Science.
, vol.314
, pp. 989-992
-
-
Dewan, A.1
Liu, M.2
Hartman, S.3
-
10
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with agerelated macular degeneration
-
Gold B, Merriam JE, Zernant J, et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with agerelated macular degeneration. Nat Genet. 2006;38:458-462.
-
(2006)
Nat Genet.
, vol.38
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
-
11
-
-
34547764305
-
Complement C3 variant and the risk of age-related macular degeneration
-
Yates JR, Sepp T, Matharu BK, et al. Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med. 2007;357:553-561.
-
(2007)
N Engl J Med.
, vol.357
, pp. 553-561
-
-
Yates, J.R.1
Sepp, T.2
Matharu, B.K.3
-
12
-
-
57649215855
-
Variation near complement factor I is associated with risk of advanced AMD
-
Fagerness JA, Maller JB, Neale BM, Reynolds RC, Daly MJ, Seddon JM. Variation near complement factor I is associated with risk of advanced AMD. Eur J Hum Genet. 2009;17:100-104.
-
(2009)
Eur J Hum Genet.
, vol.17
, pp. 100-104
-
-
Fagerness, J.A.1
Maller, J.B.2
Neale, B.M.3
Reynolds, R.C.4
Daly, M.J.5
Seddon, J.M.6
-
13
-
-
33748309136
-
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
-
Maller J, George S, Purcell S, et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet. 2006;38: 1055-1059.
-
(2006)
Nat Genet.
, vol.38
, pp. 1055-1059
-
-
Maller, J.1
George, S.2
Purcell, S.3
-
14
-
-
77952120581
-
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
-
Neale BM, Fagerness J, Reynolds R, et al. Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proc Natl Acad Sci U S A. 2010;107:7395-7400.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, pp. 7395-7400
-
-
Neale, B.M.1
Fagerness, J.2
Reynolds, R.3
-
15
-
-
77952147434
-
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration
-
Chen W, Stambolian D, Edwards AO, et al. Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A. 2010;107:7401-7406.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, pp. 7401-7406
-
-
Chen, W.1
Stambolian, D.2
Edwards, A.O.3
-
16
-
-
0028097367
-
Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy
-
Weber BH, Vogt G, Pruett RC, Stohr H, Felbor U. Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy. Nat Genet. 1994;8:352-356.
-
(1994)
Nat Genet.
, vol.8
, pp. 352-356
-
-
Weber, B.H.1
Vogt, G.2
Pruett, R.C.3
Stohr, H.4
Felbor, U.5
-
17
-
-
2942610664
-
Is medication use associated with the incidence of early age-related maculopathy? Pooled findings from 3 continents
-
van Leeuwen R, Tomany SC, Wang JJ, et al. Is medication use associated with the incidence of early age-related maculopathy? Pooled findings from 3 continents. Ophthalmology. 2004;111: 1169-1175.
-
(2004)
Ophthalmology.
, vol.111
, pp. 1169-1175
-
-
van Leeuwen, R.1
Tomany, S.C.2
Wang, J.J.3
-
18
-
-
0842349042
-
Munster age-and retina study (MARS). Association between risk factors for arteriosclerosis and age-related macular degeneration [in German]
-
Wachter A, Sun Y, Dasch B, Krause K, Pauleikhoff D, Hense HW. Munster age-and retina study (MARS). Association between risk factors for arteriosclerosis and age-related macular degeneration [in German]. Ophthalmologe. 2004;101:50-53.
-
(2004)
Ophthalmologe.
, vol.101
, pp. 50-53
-
-
Wachter, A.1
Sun, Y.2
Dasch, B.3
Krause, K.4
Pauleikhoff, D.5
Hense, H.W.6
-
19
-
-
17844406381
-
Associations of cardiovascular disease and its risk factors with age-related macular degeneration: The POLA study
-
Delcourt C, Michel F, Colvez A, Lacroux A, Delage M, Vernet MH. Associations of cardiovascular disease and its risk factors with age-related macular degeneration: the POLA study. Ophthalmic Epidemiol. 2001;8:237-249.
-
(2001)
Ophthalmic Epidemiol.
, vol.8
, pp. 237-249
-
-
Delcourt, C.1
Michel, F.2
Colvez, A.3
Lacroux, A.4
Delage, M.5
Vernet, M.H.6
-
20
-
-
20244380799
-
Changes in lipid metabolism in women with age-related macular degeneration
-
Nowak M, Swietochowska E, Marek B, et al. Changes in lipid metabolism in women with age-related macular degeneration. Clin Exp Med. 2005;4:183-187.
-
(2005)
Clin Exp Med.
, vol.4
, pp. 183-187
-
-
Nowak, M.1
Swietochowska, E.2
Marek, B.3
-
21
-
-
0036890348
-
Is age-related macular degeneration associated with serum lipoprotein and lipoparticle levels?
-
Abalain JH, Carre JL, Leglise D, et al. Is age-related macular degeneration associated with serum lipoprotein and lipoparticle levels? Clin Chim Acta. 2002;326:97-104.
-
(2002)
Clin Chim Acta.
, vol.326
, pp. 97-104
-
-
Abalain, J.H.1
Carre, J.L.2
Leglise, D.3
-
22
-
-
34249680358
-
Cardiovascular risk factors and the long-term incidence of age-related macular degeneration: The Blue Mountains Eye Study
-
Tan JS, Mitchell P, Smith W, Wang JJ. Cardiovascular risk factors and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmology. 2007;114:1143-1150.
-
(2007)
Ophthalmology.
, vol.114
, pp. 1143-1150
-
-
Tan, J.S.1
Mitchell, P.2
Smith, W.3
Wang, J.J.4
-
23
-
-
0026439413
-
The Eye Disease Case-Control Study Group
-
Risk factors for neovascular age-related macular degeneration
-
Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group. Arch Ophthalmol. 1992;110:1701-1708.
-
(1992)
Arch Ophthalmol.
, vol.110
, pp. 1701-1708
-
-
-
25
-
-
77249147331
-
The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
-
Anderson DH, Radeke MJ, Gallo NB, et al. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res. 2010;29:95-112.
-
(2010)
Prog Retin Eye Res.
, vol.29
, pp. 95-112
-
-
Anderson, D.H.1
Radeke, M.J.2
Gallo, N.B.3
-
26
-
-
75749140621
-
ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations
-
Kortvely E, Hauck SM, Duetsch G, et al. ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations. Invest Ophthalmol Vis Sci. 2010;51:79-88.
-
(2010)
Invest Ophthalmol Vis Sci.
, vol.51
, pp. 79-88
-
-
Kortvely, E.1
Hauck, S.M.2
Duetsch, G.3
-
27
-
-
0037393850
-
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
-
Qi JH, Ebrahem Q, Moore N, et al. A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med. 2003;9:407-415.
-
(2003)
Nat Med.
, vol.9
, pp. 407-415
-
-
Qi, J.H.1
Ebrahem, Q.2
Moore, N.3
-
28
-
-
77957576743
-
Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration
-
Reynolds R, Rosner B, Seddon JM. Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration. Ophthalmology. 2010;117:1989-1995.
-
(2010)
Ophthalmology.
, vol.117
, pp. 1989-1995
-
-
Reynolds, R.1
Rosner, B.2
Seddon, J.M.3
-
29
-
-
77956812723
-
Genetic causes of high and low serum HDL-cholesterol
-
Weissglas-Volkov D, Pajukanta P. Genetic causes of high and low serum HDL-cholesterol. J Lipid Res. 2010;51:2032-2057.
-
(2010)
J Lipid Res.
, vol.51
, pp. 2032-2057
-
-
Weissglas-Volkov, D.1
Pajukanta, P.2
-
30
-
-
0034958770
-
ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice
-
Vaisman BL, Lambert G, Amar M, et al. ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice. J Clin Invest. 2001;108:303-309.
-
(2001)
J Clin Invest.
, vol.108
, pp. 303-309
-
-
Vaisman, B.L.1
Lambert, G.2
Amar, M.3
-
31
-
-
67349093946
-
A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD
-
Fujihara M, Bartels E, Nielsen LB, Handa JT. A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD. Exp Eye Res. 2009;88:1115-1123.
-
(2009)
Exp Eye Res.
, vol.88
, pp. 1115-1123
-
-
Fujihara, M.1
Bartels, E.2
Nielsen, L.B.3
Handa, J.T.4
-
32
-
-
0042510743
-
Inflammatory reactions in the pathogenesis of atherosclerosis
-
Fan J, Watanabe T. Inflammatory reactions in the pathogenesis of atherosclerosis. J Atheroscler Thromb. 2003;10:63-71.
-
(2003)
J Atheroscler Thromb.
, vol.10
, pp. 63-71
-
-
Fan, J.1
Watanabe, T.2
|