EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV

Gene Therapy

Volumn 13, Issue 15, 2006, Pages 1153-1165

  Balaggan, K S ^a   Binley, K ^b   Esapa, M ^b   MacLaren, R E ^a   Iqball, S ^b   Duran, Y ^a   Pearson, R A ^a,c   Kan, O ^b   Barker, S E ^a   Smith, A J ^a   Bainbridge, J W B ^a   Naylor, S ^b   Ali, R R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b OXFORD BIOMEDICA UK LTD   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOSTATIN; ENDOSTATIN; LENTIVIRUS VECTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DRUG EFFICACY; EQUINE INFECTIOUS ANEMIA VIRUS; EXPERIMENTAL MODEL; FLUORESCENCE ANGIOGRAPHY; HISTOPATHOLOGY; IMAGE ANALYSIS; IN VIVO STUDY; LASER; LONGITUDINAL STUDY; MOUSE; MOUSE STRAIN; NICK END LABELING; NONHUMAN; PATIENT CARE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINA MACULA AGE RELATED DEGENERATION; SUBRETINAL NEOVASCULARIZATION; VIRAL GENE DELIVERY SYSTEM;

ANGIOGENESIS INHIBITORS; ANGIOSTATINS; ANIMALS; APOPTOSIS; CAPILLARY PERMEABILITY; CHOROIDAL NEOVASCULARIZATION; ENDOSTATINS; FLUORESCEIN ANGIOGRAPHY; GENE THERAPY; GENETIC VECTORS; IN SITU NICK-END LABELING; INFECTIOUS ANEMIA VIRUS, EQUINE; LASERS; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; NEOVASCULARIZATION, PATHOLOGIC; TRANSDUCTION, GENETIC; UP-REGULATION;

EQUIDAE; EQUINE INFECTIOUS ANEMIA VIRUS;

EID: 33746164355     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302769     Document Type: Article

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