TIMP-3 in Bruch's membrane: Changes during aging and in age-related macular degeneration

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 10, 1999, Pages 2367-2375

  Kamei, Motohiro ^a   Hollyfield, Joe G ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; BRUCH MEMBRANE; CHOROID; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA DEGENERATION; RETINA MACULA AGE RELATED DEGENERATION;

EID: 0032820720     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Birkedal-Hansen H, Moore W, Bodden M, et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med. 1993;4:197-250.
2. Klagsbrun M, Folkman J. Handbook of Experimental Pharmacology. New York, NY: Plenum; 1990.
3. Pavloff N, Staskus P, Kishnani NS, Hawkes SP. A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family. J Biol Chem. 1992;267:17321-17326.
4. Kishnani NS, Staskus PW, Yang TT, Masiarz FR, Hawkes SP. Identification and characterization of human tissue inhibitor of metalloproteinase-3 and detection of three additional metalloproteinase inhibitor activities in extracellular matrix. Matrix Biol. 1994;14: 479-488.
5. Apte SS, Mattei M-G, Olsen BR. Cloning of cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP-3 gene to chromosome 22. Genomics. 1994;19:86-90.
6. Apte SS, Olsen BR, Murphy G. The gene structure of tissue inhibitor of metalloproteinases-3 (TIMP-3) and its inhibitory activities define the distinct TIMP family. J Biol Chem. 1995;270:14313-14318.
7. Woessner JF. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 1991;5:2145-2154.
8. Moses MA, Langer R. A metalloproteinase inhibitor as an inhibitor of neovascularization. J Cell Biochem. 1991;47:230-235.
9. Anand-Apte B, Bao L, Smith R, et al. A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth. Biochem Cell Biol. 1996;74:853-862.
10. Anand-Apte B, Pepper M, Voest E, et al. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3. Invest Ophthatmol Vis Sci. 1997;38:817-823.
11. Leco K, Khokha R, Pavloff N, Hawkesi S, Edwards D. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J Biol Chem. 1994;269:9352-9360.
12. Fariss RN, Apte SS, Olsen BR, Milam AH, Iwata K. Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye. Am J Pathol. 1997;150:323-328.
13. Kamei M, Apte S, Lewis H, Hollyfield JG. TIMP-3 accumulation in Bruch's membrane and drusen in eyes from normal and age-related macular degeneration donors. In: LaVail MM, Hollyfield JG, Anderson RE, eds. Degenerative Retinal Diseases. New York, Plenum Press; 1997:11-15.
14. Della NG, Campochiaro PA, Zack DJ. Localization of TIMP-3 mRNA expression to the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1996;37:1921-1924.
15. Ruiz A, Brett P, Bok D. TIMP-3 is expressed in human retinal pigment epithelium. Biochem Biophys Res Commun. 1996;226: 467-474.
16. Weber BH, Vogt G, Pruett RC, Stohr H, Felbor U. Mutations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) in patients with Sorsby's fundus dystrophy. Nat Genet. 1994;8:352-356.
17. Fariss RN, Apte SS, Luthert PJ, Bird AC, Milam AH. Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa. Br J Ophthalmol. 1998;82:1329-1334.
18. Felbor U, Doepner D, Schneider U, Zrenner E, Weber BH. Evaluation of the gene encoding the tissue inhibitor of metalloproteinases-3 in various maculopathies. Invest Ophthalmol Vis Sci. 1997; 38:1054-1059.
19. De La Paz MA, Pericak-Vance MA, Lennon FJLH, Seddon JM. Exclusion of TIMP-3 as a candidate locus in age-related macular degeneration. Invest Ophthalmol Vis Sci. 1997;38:1060-1065.
20. Piguet B, Wells J, Palmvangi I, Wormald R, Chisholm I, Bird A. Age-related Bruch's membrane change: a clinical study of the relative role of heredity and environment. Br J Ophthalmol. 1993; 77:400-403.
21. Green WR, Enger C. Age-related macular degeneration histopathologic studies: the 1992 Lorenz E. Zimmerman Lecture. Ophthalmology. 1993;100:1519-1535.
22. Curcio C, Medeiros N, Millican C. The Alabama Age-Related Macular Degeneration Grading System for donor eyes. Invest Ophthalmol Vis Sci. 1998;39:1085-1096.
23. Yamada M, Tsukagoshii H, Otomo E, Hayakawa M. Systemic amyloid deposition in old age and dementia of Alzheimer type: the relationship of brain amyloid to other amyloid. Acta Neuropathol. 1988;77:136-141.
24. McFall-Ngai M, Ding L, Takemoto L, Horwitz J. Spatial and temporal mapping of the age-related changes in human lens crystallins. Exp Eye Res. 1985;41:745-758.
25. Heiba IM, Elston RC, Klein EK, Klein R. Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study. Genet Epidemiol. 1994;11:51-67.
26. Seddon JM, Ajani UA, Mitchell BD. Familial aggregation of age-related maculopathy. Am J Ophthalmol. 1997;123:199-206.
27. Allikmets R, Shroyer N, Singh N, et al. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science. 1997;277:1805-1807.
28. The Eye Disease Case-Control Study Group. Risk factors for neovascular age-related macular degeneration. Arch Ophthalmol. 1992;110:1701-1708.
29. West S, Vitale S, Halfrisch J, Munoz B, Muller D, Bressler S, Bressler N. Are antioxidants or supplements protective for age-related macular degeneration? Arch Ophthalmol. 1994;112:222-227.
30. Gottsch J, Bynoe L, Harlan J, Rencs E, Green W. Light-induced deposits in Bruch's membrane of protoporphyric mice. Arch Ophthalmol. 1993;111:126-129.
31. Hammond BR Jr, Wooten BR, Snodderly DM. Cigarette smoking and retinal carotenoids: implications for age-related macular degeneration. Vision Res. 1996;36:3003-3009.
32. Eldred G. Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular degeneration. Gerontology. 1995;41(suppl 2):15-28.
33. Rakoczy P, Baines M, Kennedy C, Constable I. Correlation between autofluorescent debris accumulation and the presence of partially processed forms of cathepsin D in cultured retinal pigment epithelial cells challenged with rod outer segments. Exp Eye Res. 1996;63:159-167.