The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization

Molecular Immunology

Volumn 48, Issue 6-7, 2011, Pages

  Rohrer, Bärbel ^a   Coughlin, Beth ^a   Kunchithapautham, Kannan ^a   Long, Qin ^a   Tomlinson, Stephen ^a   Takahashi, Kazue ^b   Holers, V Michael ^c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Age related macular degeneration; Alternative pathway; Choroidal neovascularization; Complement activation; Mouse model; PEDF; VEGF

Indexed keywords

COMPLEMENT COMPONENT C5A; PIGMENT EPITHELIUM DERIVED FACTOR; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; DISEASE COURSE; GENE INACTIVATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SUBRETINAL NEOVASCULARIZATION; WILD TYPE;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; CHOROIDAL NEOVASCULARIZATION; COMPLEMENT PATHWAY, ALTERNATIVE; COMPLEMENT SYSTEM PROTEINS; ELECTRORETINOGRAPHY; GENE EXPRESSION REGULATION; LASERS; MICE; PHOTORECEPTOR CELLS, VERTEBRATE; RETINA; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 79951551543     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.12.016     Document Type: Article

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