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Volumn 5, Issue 4, 2013, Pages 1-22

Base excision repair

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EID: 84870763054     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a012583     Document Type: Article
Times cited : (936)

References (173)
  • 2
    • 0030912695 scopus 로고    scopus 로고
    • Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue
    • Aburatani H, Hippo Y, Ishida T, Takashima R, Matsuba C, Kodama T, Takao M, Yasui A, Yamamoto K, Asano M. 1997. Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. Cancer Res 57: 2151-2156.
    • (1997) Cancer Res , vol.57 , pp. 2151-2156
    • Aburatani, H.1    Hippo, Y.2    Ishida, T.3    Takashima, R.4    Matsuba, C.5    Kodama, T.6    Takao, M.7    Yasui, A.8    Yamamoto, K.9    Asano, M.10
  • 3
    • 6044230603 scopus 로고    scopus 로고
    • Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells
    • Akbari M, Otterlei M, Pena-Diaz J, Aas PA, Kavli B, Liabakk NB, Hagen L, Imai K, Durandy A, Slupphaug G, et al. 2004. Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. Nucleic Acids Res 32: 5486-5498.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5486-5498
    • Akbari, M.1    Otterlei, M.2    Pena-Diaz, J.3    Aas, P.A.4    Kavli, B.5    Liabakk, N.B.6    Hagen, L.7    Imai, K.8    Durandy, A.9    Slupphaug, G.10
  • 4
    • 34247173885 scopus 로고    scopus 로고
    • Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress
    • Akbari M, Otterlei M, Pena-Diaz J, Krokan HE. 2007. Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress. Neuroscience 145: 1201-1212.
    • (2007) Neuroscience , vol.145 , pp. 1201-1212
    • Akbari, M.1    Otterlei, M.2    Pena-Diaz, J.3    Krokan, H.E.4
  • 5
    • 40649109989 scopus 로고    scopus 로고
    • Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis
    • Akbari M, Visnes T, Krokan HE, Otterlei M. 2008. Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis. DNA Repair (Amst) 7: 605-616.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 605-616
    • Akbari, M.1    Visnes, T.2    Krokan, H.E.3    Otterlei, M.4
  • 6
    • 67349099614 scopus 로고    scopus 로고
    • Extracts of proliferating and nonproliferating human cells display different base excision pathways and repair fidelity
    • Akbari M, Pena-Diaz J, Andersen S, Liabakk NB, Otterlei M, Krokan HE. 2009. Extracts of proliferating and nonproliferating human cells display different base excision pathways and repair fidelity. DNA Repair (Amst) 8: 834- 843.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 834
    • Akbari, M.1    Pena-Diaz, J.2    Andersen, S.3    Liabakk, N.B.4    Otterlei, M.5    Krokan, H.E.6
  • 7
    • 34247599335 scopus 로고    scopus 로고
    • A unified view of base excision repair: Lesion-dependent protein complexes regulated by post-translational modification
    • Almeida KH, Sobol RW. 2007. A unified view of base excision repair: Lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst) 6: 695-711.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 695-711
    • Almeida, K.H.1    Sobol, R.W.2
  • 9
    • 16244423009 scopus 로고    scopus 로고
    • Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts
    • Andersen S, Heine T, Sneve R, Konig I, Krokan HE, Epe B, Nilsen H. 2005. Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts. Carcinogenesis 26: 547-555.
    • (2005) Carcinogenesis , vol.26 , pp. 547-555
    • Andersen, S.1    Heine, T.2    Sneve, R.3    Konig, I.4    Krokan, H.E.5    Epe, B.6    Nilsen, H.7
  • 11
    • 0037125133 scopus 로고    scopus 로고
    • A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII
    • Bandaru V, Sunkara S, Wallace SS, Bond JP. 2002. A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII. DNA Repair (Amst) 1: 517-529.
    • (2002) DNA Repair (Amst) , vol.1 , pp. 517-529
    • Bandaru, V.1    Sunkara, S.2    Wallace, S.S.3    Bond, J.P.4
  • 12
    • 4544322045 scopus 로고    scopus 로고
    • Free radicals and aging
    • Barja G. 2004. Free radicals and aging. Trends Neurosci 27: 595-600.
    • (2004) Trends Neurosci , vol.27 , pp. 595-600
    • Barja, G.1
  • 13
    • 84862503948 scopus 로고    scopus 로고
    • Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase
    • Bashtrykov P, Ragozin S, Jeltsch A. 2012. Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase. FEBS Lett 586: 1821-1823.
    • (2012) FEBS Lett , vol.586 , pp. 1821-1823
    • Bashtrykov, P.1    Ragozin, S.2    Jeltsch, A.3
  • 14
    • 84855490596 scopus 로고    scopus 로고
    • Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress
    • Bauer M, Goldstein M, Christmann M, Becker H, Heylmann D, Kaina B. 2011. Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress. Proc Natl Acad Sci 108: 21105-21110.
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 21105-21110
    • Bauer, M.1    Goldstein, M.2    Christmann, M.3    Becker, H.4    Heylmann, D.5    Kaina, B.6
  • 15
    • 33644634986 scopus 로고    scopus 로고
    • Structure and mechanism of DNA polymerase b
    • Beard WA, Wilson SH. 2006. Structure and mechanism of DNA polymerase b. Chem Rev 106: 361-382.
    • (2006) Chem Rev , vol.106 , pp. 361-382
    • Beard, W.A.1    Wilson, S.H.2
  • 16
    • 33745211646 scopus 로고    scopus 로고
    • Activities and mechanism of DNA polymerase b
    • Beard WA, Prasad R, Wilson SH. 2006. Activities and mechanism of DNA polymerase b. Methods Enzymol 408: 91-107.
    • (2006) Methods Enzymol , vol.408 , pp. 91-107
    • Beard, W.A.1    Prasad, R.2    Wilson, S.H.3
  • 17
    • 50549086678 scopus 로고    scopus 로고
    • Uracil in DNA: Consequences for carcinogenesis and chemotherapy
    • Berger SH, Pittman DL, Wyatt MD. 2008. Uracil in DNA: Consequences for carcinogenesis and chemotherapy. Biochem Pharmacol 76: 697-706.
    • (2008) Biochem Pharmacol , vol.76 , pp. 697-706
    • Berger, S.H.1    Pittman, D.L.2    Wyatt, M.D.3
  • 18
    • 33644635257 scopus 로고    scopus 로고
    • Toward a detailed understanding of base excision repair enzymes: Transition state and mechanistic analyses of N-glycoside hydrolysis and N-glycoside transfer
    • Berti PJ, McCann JA. 2006. Toward a detailed understanding of base excision repair enzymes: Transition state and mechanistic analyses of N-glycoside hydrolysis and N-glycoside transfer. Chem Rev 106: 506-555.
    • (2006) Chem Rev , vol.106 , pp. 506-555
    • Berti, P.J.1    McCann, J.A.2
  • 19
    • 0030703177 scopus 로고    scopus 로고
    • Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
    • Bjoras M, Luna L, Johnsen B, Hoff E, Haug T, Rognes T, Seeberg E. 1997. Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J 16: 6314-6322.
    • (1997) EMBO J , vol.16 , pp. 6314-6322
    • Bjoras, M.1    Luna, L.2    Johnsen, B.3    Hoff, E.4    Haug, T.5    Rognes, T.6    Seeberg, E.7
  • 22
    • 33750614308 scopus 로고    scopus 로고
    • Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition
    • Broderick P, Bagratuni T, Vijayakrishnan J, Lubbe S, Chandler I, Houlston RS. 2006. Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition. BMC Cancer 6: 243.
    • (2006) BMC Cancer , vol.6 , pp. 243
    • Broderick, P.1    Bagratuni, T.2    Vijayakrishnan, J.3    Lubbe, S.4    Chandler, I.5    Houlston, R.S.6
  • 24
    • 84866284780 scopus 로고    scopus 로고
    • Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice
    • Canugovi C, Yoon JS, Feldman NH, Croteau DL, Mattson MP, Bohr VA. 2012. Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice. Proc Natl Acad Sci 109: 14948-14953.
    • (2012) Proc Natl Acad Sci , vol.109 , pp. 14948-14953
    • Canugovi, C.1    Yoon, J.S.2    Feldman, N.H.3    Croteau, D.L.4    Mattson, M.P.5    Bohr, V.A.6
  • 25
    • 0348111465 scopus 로고    scopus 로고
    • Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I
    • Cao C, Kwon K, Jiang YL, Drohat AC, Stivers JT. 2003. Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I. J Biol Chem 278: 48012- 48020.
    • (2003) J Biol Chem , vol.278 , pp. 48012-48020
    • Cao, C.1    Kwon, K.2    Jiang, Y.L.3    Drohat, A.C.4    Stivers, J.T.5
  • 26
    • 16544386633 scopus 로고    scopus 로고
    • Dynamic opening of DNA during the enzymatic search for a damaged base
    • Cao C, Jiang YL, Stivers JT, Song F. 2004. Dynamic opening of DNA during the enzymatic search for a damaged base. Nat Struct Mol Biol 11: 1230-1236.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1230-1236
    • Cao, C.1    Jiang, Y.L.2    Stivers, J.T.3    Song, F.4
  • 28
    • 84856583250 scopus 로고    scopus 로고
    • Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae
    • Collura A, Kemp PA, Boiteux S. 2012. Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11: 294-303.
    • (2012) DNA Repair (Amst) , vol.11 , pp. 294-303
    • Collura, A.1    Kemp, P.A.2    Boiteux, S.3
  • 29
    • 34249807921 scopus 로고    scopus 로고
    • DNA deamination in immunity: AID in the context of its APOBEC relatives
    • Conticello SG, Langlois MA, Yang Z, Neuberger MS. 2007. DNA deamination in immunity: AID in the context of its APOBEC relatives. Adv Immunol 94: 37-73.
    • (2007) Adv Immunol , vol.94 , pp. 37-73
    • Conticello, S.G.1    Langlois, M.A.2    Yang, Z.3    Neuberger, M.S.4
  • 33
    • 34249862768 scopus 로고    scopus 로고
    • Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats
    • Dalhus B, Helle IH, Backe PH, Alseth I, Rognes T, Bjoras M, Laerdahl JK. 2007. Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats. Nucleic Acids Res 35: 2451-2459.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2451-2459
    • Dalhus, B.1    Helle, I.H.2    Backe, P.H.3    Alseth, I.4    Rognes, T.5    Bjoras, M.6    Laerdahl, J.K.7
  • 35
    • 34250900982 scopus 로고    scopus 로고
    • Base-excision repair of oxidative DNA damage
    • David SS, O'Shea VL, Kundu S. 2007. Base-excision repair of oxidative DNA damage. Nature 447: 941-950.
    • (2007) Nature , vol.447 , pp. 941-950
    • David, S.S.1    O'Shea, V.L.2    Kundu, S.3
  • 37
    • 3343022751 scopus 로고    scopus 로고
    • An evolutionary analysis of the helix-hairpin-helix superfamily of DNA repair glycosylases
    • Denver DR, Swenson SL, Lynch M. 2003. An evolutionary analysis of the helix-hairpin-helix superfamily of DNA repair glycosylases. Mol Biol Evol 20: 1603-1611.
    • (2003) Mol Biol Evol , vol.20 , pp. 1603-1611
    • Denver, D.R.1    Swenson, S.L.2    Lynch, M.3
  • 38
    • 84861231399 scopus 로고    scopus 로고
    • The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art
    • De Vos M, Schreiber V, Dantzer F. 2012. The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art. Biochem Pharmacol 84: 137-146.
    • (2012) Biochem Pharmacol , vol.84 , pp. 137-146
    • de Vos, M.1    Schreiber, V.2    Dantzer, F.3
  • 39
    • 34249790004 scopus 로고    scopus 로고
    • Molecular mechanisms of antibody somatic hypermutation
    • Di Noia JM, Neuberger MS. 2007. Molecular mechanisms of antibody somatic hypermutation. Annu Rev Biochem 76: 1-22.
    • (2007) Annu Rev Biochem , vol.76 , pp. 1-22
    • Di Noia, J.M.1    Neuberger, M.S.2
  • 40
    • 84861479923 scopus 로고    scopus 로고
    • Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil
    • Doseth B, Ekre C, Slupphaug G, Krokan HE, Kavli B. 2012. Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil. DNA Repair (Amst) 11: 587- 593.
    • (2012) DNA Repair (Amst) , vol.11 , pp. 587
    • Doseth, B.1    Ekre, C.2    Slupphaug, G.3    Krokan, H.E.4    Kavli, B.5
  • 41
    • 0347379928 scopus 로고    scopus 로고
    • Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
    • Dou H, Mitra S, Hazra TK. 2003. Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. J Biol Chem 278: 49679-49684.
    • (2003) J Biol Chem , vol.278 , pp. 49679-49684
    • Dou, H.1    Mitra, S.2    Hazra, T.K.3
  • 42
    • 0036730599 scopus 로고    scopus 로고
    • 3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member
    • Drohat AC, Kwon K, Krosky DJ, Stivers JT. 2002. 3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member. Nat Struct Biol 9: 659- 664.
    • Nat Struct Biol , vol.9 , pp. 659
    • Drohat, A.C.1    Kwon, K.2    Krosky, D.J.3    Stivers, J.T.4
  • 43
    • 33846025805 scopus 로고    scopus 로고
    • ' -terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase l
    • ' -terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase l. J Biol Chem 281: 35649-35655.
    • (2006) J Biol Chem , vol.281 , pp. 35649-35655
    • Duym, W.W.1    Fiala, K.A.2    Bhatt, N.3    Suo, Z.4
  • 44
    • 0141754009 scopus 로고    scopus 로고
    • Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
    • Eichman BF, O'Rourke EJ, Radicella JP, Ellenberger T. 2003. Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases. EMBO J 22: 4898-4909.
    • (2003) EMBO J , vol.22 , pp. 4898-4909
    • Eichman, B.F.1    O'Rourke, E.J.2    Radicella, J.P.3    Ellenberger, T.4
  • 46
    • 36549061567 scopus 로고    scopus 로고
    • 5-Fluorouracil is efficiently removed from DNA by the base excision and mismatch repair systems
    • Fischer F, Baerenfaller K, Jiricny J. 2007. 5-Fluorouracil is efficiently removed from DNA by the base excision and mismatch repair systems. Gastroenterology 133: 1858- 1868.
    • Gastroenterology , vol.133 , pp. 1858-1868
    • Fischer, F.1    Baerenfaller, K.2    Jiricny, J.3
  • 47
    • 34547225606 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase
    • Fisher AE, Hochegger H, Takeda S, Caldecott KW. 2007. Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase. Mol Cell Biol 27: 5597-5605.
    • (2007) Mol Cell Biol , vol.27 , pp. 5597-5605
    • Fisher, A.E.1    Hochegger, H.2    Takeda, S.3    Caldecott, K.W.4
  • 48
    • 67650302611 scopus 로고    scopus 로고
    • Cat alytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
    • Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjoras M, Boberg KM, Alseth I. 2009. Cat alytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. Carcinogenesis 30: 1147-1154.
    • (2009) Carcinogenesis , vol.30 , pp. 1147-1154
    • Forsbring, M.1    Vik, E.S.2    Dalhus, B.3    Karlsen, T.H.4    Bergquist, A.5    Schrumpf, E.6    Bjoras, M.7    Boberg, K.M.8    Alseth, I.9
  • 49
    • 33847625356 scopus 로고    scopus 로고
    • Base damage and single-strand break repair: Mechanisms and functional significance of short- and long-patch repair subpathways
    • Fortini P, Dogliotti E. 2007. Base damage and single-strand break repair: Mechanisms and functional significance of short- and long-patch repair subpathways. DNA Repair (Amst) 6: 398-409.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 398-409
    • Fortini, P.1    Dogliotti, E.2
  • 50
    • 0033591336 scopus 로고    scopus 로고
    • The type of DNA glycosylase determines the base excision repair pathway in mammalian cells
    • Fortini P, Parlanti E, Sidorkina OM, Laval J, Dogliotti E. 1999. The type of DNA glycosylase determines the base excision repair pathway in mammalian cells. J Biol Chem 274: 15230-15236.
    • (1999) J Biol Chem , vol.274 , pp. 15230-15236
    • Fortini, P.1    Parlanti, E.2    Sidorkina, O.M.3    Laval, J.4    Dogliotti, E.5
  • 51
    • 30344455023 scopus 로고    scopus 로고
    • Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7
    • Friedberg EC, Meira LB. 2006. Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7. DNA Repair (Amst) 5: 189-209.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 189-209
    • Friedberg, E.C.1    Meira, L.B.2
  • 53
    • 77953654163 scopus 로고    scopus 로고
    • Detection of damaged DNA bases by DNA glycosylase enzymes
    • Friedman JI, Stivers JT. 2010. Detection of damaged DNA bases by DNA glycosylase enzymes. Biochemistry 49: 4957-4967.
    • (2010) Biochemistry , vol.49 , pp. 4957-4967
    • Friedman, J.I.1    Stivers, J.T.2
  • 54
    • 79952368682 scopus 로고    scopus 로고
    • DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair
    • Gao Y, Katyal S, Lee Y, Zhao J, Rehg JE, Russell HR, McKinnon PJ. 2011. DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair. Nature 471: 240-244.
    • (2011) Nature , vol.471 , pp. 240-244
    • Gao, Y.1    Katyal, S.2    Lee, Y.3    Zhao, J.4    Rehg, J.E.5    Russell, H.R.6    McKinnon, P.J.7
  • 55
    • 84862758175 scopus 로고    scopus 로고
    • New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
    • Gibson BA, Kraus WL. 2012. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nat Rev Mol Cell Biol 13: 411-424.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 411-424
    • Gibson, B.A.1    Kraus, W.L.2
  • 56
    • 77951285397 scopus 로고    scopus 로고
    • The role of mammalian NEIL1 protein in the repair of 8-oxo-7,8-dihydroadenine in DNA
    • Grin IR, Dianov GL, Zharkov DO. 2010. The role of mammalian NEIL1 protein in the repair of 8-oxo-7,8-dihydroadenine in DNA. FEBS Lett 584: 1553-1557.
    • (2010) FEBS Lett , vol.584 , pp. 1553-1557
    • Grin, I.R.1    Dianov, G.L.2    Zharkov, D.O.3
  • 57
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase b gene segment in T cells using cell type-specific gene targeting
    • Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K. 1994. Deletion of a DNA polymerase b gene segment in T cells using cell type-specific gene targeting. Science 265: 103-106.
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 59
    • 0242412184 scopus 로고    scopus 로고
    • Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae
    • Guillet M, Boiteux S. 2003. Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae. Mol Cell Biol 23: 8386-8394.
    • (2003) Mol Cell Biol , vol.23 , pp. 8386-8394
    • Guillet, M.1    Boiteux, S.2
  • 61
    • 7944222565 scopus 로고    scopus 로고
    • Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2
    • Hailer MK, Slade PG, Martin BD, Rosenquist TA, Sugden KD. 2005. Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2. DNA Repair (Amst) 4: 41-50.
    • (2005) DNA Repair (Amst) , vol.4 , pp. 41-50
    • Hailer, M.K.1    Slade, P.G.2    Martin, B.D.3    Rosenquist, T.A.4    Sugden, K.D.5
  • 63
    • 34547101263 scopus 로고    scopus 로고
    • Cell cycle regulation as a mechanism for functional separation of the apparently redundant uracil DNA glycosylases TDG and UNG2
    • Hardeland U, Kunz C, Focke F, Szadkowski M, Schar P. 2007. Cell cycle regulation as a mechanism for functional separation of the apparently redundant uracil DNA glycosylases TDG and UNG2. Nucleic Acids Res 35: 3859-3867.
    • (2007) Nucleic Acids Res , vol.35 , pp. 3859-3867
    • Hardeland, U.1    Kunz, C.2    Focke, F.3    Szadkowski, M.4    Schar, P.5
  • 65
    • 84866887356 scopus 로고    scopus 로고
    • Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: Structural basis and implications for active DNA demethylation
    • Hashimoto H, Zhang X, Cheng X. 2012b. Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: Structural basis and implications for active DNA demethylation. Nucleic Acids Res 40: 8276-8284.
    • (2012) Nucleic Acids Res , vol.40 , pp. 8276-8284
    • Hashimoto, H.1    Zhang, X.2    Cheng, X.3
  • 66
    • 0037133684 scopus 로고    scopus 로고
    • Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
    • Hazra TK, Izumi T, Boldogh I, Imhoff B, Kow YW, Jaruga P, Dizdaroglu M, Mitra S. 2002a. Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proc Natl Acad Sci 99: 3523-3528.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 3523-3528
    • Hazra, T.K.1    Izumi, T.2    Boldogh, I.3    Imhoff, B.4    Kow, Y.W.5    Jaruga, P.6    Dizdaroglu, M.7    Mitra, S.8
  • 67
    • 0037162995 scopus 로고    scopus 로고
    • Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions
    • Hazra TK, Kow YW, Hatahet Z, Imhoff B, Boldogh I, Mokkapati SK, Mitra S, Izumi T. 2002b. Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions. J Biol Chem 277: 30417-30420.
    • (2002) J Biol Chem , vol.277 , pp. 30417-30420
    • Hazra, T.K.1    Kow, Y.W.2    Hatahet, Z.3    Imhoff, B.4    Boldogh, I.5    Mokkapati, S.K.6    Mitra, S.7    Izumi, T.8
  • 68
    • 38049112778 scopus 로고    scopus 로고
    • Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
    • Hegde ML, Hazra TK, Mitra S. 2008a. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res 18: 27-47.
    • (2008) Cell Res , vol.18 , pp. 27-47
    • Hegde, M.L.1    Hazra, T.K.2    Mitra, S.3
  • 69
    • 55249083320 scopus 로고    scopus 로고
    • Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1
    • Hegde ML, Theriot CA, Das A, Hegde PM, Guo Z, Gary RK, Hazra TK, Shen B, Mitra S. 2008b. Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1. J Biol Chem 283: 27028-27037.
    • (2008) J Biol Chem , vol.283 , pp. 27028-27037
    • Hegde, M.L.1    Theriot, C.A.2    Das, A.3    Hegde, P.M.4    Guo, Z.5    Gary, R.K.6    Hazra, T.K.7    Shen, B.8    Mitra, S.9
  • 70
    • 78149469033 scopus 로고    scopus 로고
    • Functions of disordered regions in mammalian early base excision repair proteins
    • Hegde ML, Hazra TK, Mitra S. 2010. Functions of disordered regions in mammalian early base excision repair proteins. Cell Mol Life Sci 67: 3573-3587.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 3573-3587
    • Hegde, M.L.1    Hazra, T.K.2    Mitra, S.3
  • 71
    • 0034651873 scopus 로고    scopus 로고
    • DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA
    • Hollis T, Ichikawa Y, Ellenberger T. 2000. DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA. EMBO J 19: 758-766.
    • (2000) EMBO J , vol.19 , pp. 758-766
    • Hollis, T.1    Ichikawa, Y.2    Ellenberger, T.3
  • 72
    • 33847669187 scopus 로고    scopus 로고
    • Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency
    • Horton JK, Wilson SH. 2007. Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency. DNA Repair (Amst) 6: 530-543.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 530-543
    • Horton, J.K.1    Wilson, S.H.2
  • 73
    • 24044460415 scopus 로고    scopus 로고
    • DNA base damage recognition and removal: New twists and grooves
    • Huffman JL, Sundheim O, Tainer JA. 2005. DNA base damage recognition and removal: New twists and grooves. Mutat Res 577: 55-76.
    • (2005) Mutat Res , vol.577 , pp. 55-76
    • Huffman, J.L.1    Sundheim, O.2    Tainer, J.A.3
  • 75
    • 84859749531 scopus 로고    scopus 로고
    • DNA glycosylases: In DNA repair and beyond
    • Jacobs AL, Schar P. 2012. DNA glycosylases: In DNA repair and beyond. Chromosoma 121: 1-20.
    • (2012) Chromosoma , vol.121 , pp. 1-20
    • Jacobs, A.L.1    Schar, P.2
  • 78
    • 35148820034 scopus 로고    scopus 로고
    • A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine
    • Johnson RE, Yu SL, Prakash S, Prakash L. 2007. A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine. Mol Cell Biol 27: 7198-7205.
    • (2007) Mol Cell Biol , vol.27 , pp. 7198-7205
    • Johnson, R.E.1    Yu, S.L.2    Prakash, S.3    Prakash, L.4
  • 81
    • 33847621554 scopus 로고    scopus 로고
    • Uracil in DNA-general mutagen, but normal intermediate in acquired immunity
    • Kavli B, Otterlei M, Slupphaug G, Krokan HE. 2007. Uracil in DNA-general mutagen, but normal intermediate in acquired immunity. DNA Repair (Amst) 6: 505-516.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 505-516
    • Kavli, B.1    Otterlei, M.2    Slupphaug, G.3    Krokan, H.E.4
  • 82
    • 84864452214 scopus 로고    scopus 로고
    • Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice
    • Kemmerich K, Dingler FA, Rada C, Neuberger MS. 2012. Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice. Nucleic Acids Res 40: 6016- 6025.
    • (2012) Nucleic Acids Res , vol.40 , pp. 6016
    • Kemmerich, K.1    Dingler, F.A.2    Rada, C.3    Neuberger, M.S.4
  • 84
    • 0037115911 scopus 로고    scopus 로고
    • Uracil in DNA- occurrence, consequences and repair
    • Krokan HE, Drablos F, Slupphaug G. 2002. Uracil in DNA- occurrence, consequences and repair. Oncogene 21: 8935-8948.
    • (2002) Oncogene , vol.21 , pp. 8935-8948
    • Krokan, H.E.1    Drablos, F.2    Slupphaug, G.3
  • 86
    • 34547195827 scopus 로고    scopus 로고
    • The E295K DNA polymerase b gastric cancer-associated variant interferes with base excision repair and induces cellular transformation
    • Lang T, Dalal S, Chikova A, DiMaio D, Sweasy JB. 2007. The E295K DNA polymerase b gastric cancer-associated variant interferes with base excision repair and induces cellular transformation. Mol Cell Biol 27: 5587-5596.
    • (2007) Mol Cell Biol , vol.27 , pp. 5587-5596
    • Lang, T.1    Dalal, S.2    Chikova, A.3    Dimaio, D.4    Sweasy, J.B.5
  • 87
    • 0032538337 scopus 로고    scopus 로고
    • Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: Mechanisms for nucleotide flipping and base excision
    • Lau AY, Scharer OD, Samson L, Verdine GL, Ellenberger T. 1998. Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: Mechanisms for nucleotide flipping and base excision. Cell 95: 249-258.
    • (1998) Cell , vol.95 , pp. 249-258
    • Lau, A.Y.1    Scharer, O.D.2    Samson, L.3    Verdine, G.L.4    Ellenberger, T.5
  • 88
    • 0034610336 scopus 로고    scopus 로고
    • Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
    • Lau AY, Wyatt MD, Glassner BJ, Samson LD, Ellenberger T. 2000. Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc Natl Acad Sci 97: 13573-13578.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 13573-13578
    • Lau, A.Y.1    Wyatt, M.D.2    Glassner, B.J.3    Samson, L.D.4    Ellenberger, T.5
  • 89
    • 0000476915 scopus 로고
    • An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues
    • Lindahl T. 1974. An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc Natl Acad Sci 71: 3649-3653.
    • (1974) Proc Natl Acad Sci , vol.71 , pp. 3649-3653
    • Lindahl, T.1
  • 90
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl T. 1993. Instability and decay of the primary structure of DNA. Nature 362: 709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 92
    • 77953484497 scopus 로고    scopus 로고
    • DNA repair in mammalian mitochondria: Much more than we thought?
    • Liu P, Demple B. 2010. DNA repair in mammalian mitochondria: Much more than we thought? Environ Mol Mutagen 51: 417-426.
    • (2010) Environ Mol Mutagen , vol.51 , pp. 417-426
    • Liu, P.1    Demple, B.2
  • 95
    • 74549121930 scopus 로고    scopus 로고
    • HMGB1: Roles in base excision repair and related function
    • Liu Y, Prasad R, Wilson SH. 2010b. HMGB1: Roles in base excision repair and related function. Biochim Biophys Acta 1799: 119-130.
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 119-130
    • Liu, Y.1    Prasad, R.2    Wilson, S.H.3
  • 97
    • 0031172802 scopus 로고    scopus 로고
    • A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer
    • Lu R, Nash HM, Verdine GL. 1997. A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer. Curr Biol 7: 397-407.
    • (1997) Curr Biol , vol.7 , pp. 397-407
    • Lu, R.1    Nash, H.M.2    Verdine, G.L.3
  • 98
    • 79952147727 scopus 로고    scopus 로고
    • Phylogenomic analysis of the uracil-DNA glycosylase superfamily
    • Lucas-Lledo JI, Maddamsetti R, Lynch M. 2011. Phylogenomic analysis of the uracil-DNA glycosylase superfamily. Mol Biol Evol 28: 1307-1317.
    • (2011) Mol Biol Evol , vol.28 , pp. 1307-1317
    • Lucas-Lledo, J.I.1    Maddamsetti, R.2    Lynch, M.3
  • 99
    • 77955964086 scopus 로고    scopus 로고
    • AID and somatic hypermutation
    • Maul RW, Gearhart PJ. 2010a. AID and somatic hypermutation. Adv Immunol 105: 159-191.
    • (2010) Adv Immunol , vol.105 , pp. 159-191
    • Maul, R.W.1    Gearhart, P.J.2
  • 100
    • 77953962524 scopus 로고    scopus 로고
    • Controlling somatic hypermutation in immunoglobulin variable and switch regions
    • Maul RW, Gearhart PJ. 2010b. Controlling somatic hypermutation in immunoglobulin variable and switch regions. Immunol Res 47: 113-122.
    • (2010) Immunol Res , vol.47 , pp. 113-122
    • Maul, R.W.1    Gearhart, P.J.2
  • 102
    • 34548239142 scopus 로고    scopus 로고
    • ATP-dependent chromatin remodeling is required for base excision repair in conventional but not in variant H2A.Bbd nucleosomes
    • Menoni H, Gasparutto D, Hamiche A, Cadet J, Dimitrov S, Bouvet P, Angelov D. 2007. ATP-dependent chromatin remodeling is required for base excision repair in conventional but not in variant H2A.Bbd nucleosomes. Mol Cell Biol 27: 5949-5956.
    • (2007) Mol Cell Biol , vol.27 , pp. 5949-5956
    • Menoni, H.1    Gasparutto, D.2    Hamiche, A.3    Cadet, J.4    Dimitrov, S.5    Bouvet, P.6    Angelov, D.7
  • 103
    • 34247555529 scopus 로고    scopus 로고
    • DNA damage recognition and repair by 3-methyladenine DNA glycosylase I (TAG)
    • Metz AH, Hollis T, Eichman BF. 2007. DNA damage recognition and repair by 3-methyladenine DNA glycosylase I (TAG). EMBO J 26: 2411-2420.
    • (2007) EMBO J , vol.26 , pp. 2411-2420
    • Metz, A.H.1    Hollis, T.2    Eichman, B.F.3
  • 104
    • 0028934537 scopus 로고
    • Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis
    • Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE, Tainer JA. 1995. Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis. Cell 80: 869-878.
    • (1995) Cell , vol.80 , pp. 869-878
    • Mol, C.D.1    Arvai, A.S.2    Slupphaug, G.3    Kavli, B.4    Alseth, I.5    Krokan, H.E.6    Tainer, J.A.7
  • 105
    • 0034719372 scopus 로고    scopus 로고
    • DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]
    • Mol CD, Izumi T, Mitra S, Tainer JA. 2000. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]. Nature 403: 451-456.
    • (2000) Nature , vol.403 , pp. 451-456
    • Mol, C.D.1    Izumi, T.2    Mitra, S.3    Tainer, J.A.4
  • 108
    • 0037112668 scopus 로고    scopus 로고
    • Human DNA glycosylases of the bacterial Fpg/ MutM superfamily: An alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA
    • Morland I, Rolseth V, Luna L, Rognes T, Bjoras M, Seeberg E. 2002. Human DNA glycosylases of the bacterial Fpg/ MutM superfamily: An alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA. Nucleic Acids Res 30: 4926-4936.
    • (2002) Nucleic Acids Res , vol.30 , pp. 4926-4936
    • Morland, I.1    Rolseth, V.2    Luna, L.3    Rognes, T.4    Bjoras, M.5    Seeberg, E.6
  • 109
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu M, Sankaranand VS, Anant S, Sugai M, Kinoshita K, Davidson NO, Honjo T. 1999. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem 274: 18470-18476.
    • (1999) J Biol Chem , vol.274 , pp. 18470-18476
    • Muramatsu, M.1    Sankaranand, V.S.2    Anant, S.3    Sugai, M.4    Kinoshita, K.5    Davidson, N.O.6    Honjo, T.7
  • 110
    • 84863533866 scopus 로고    scopus 로고
    • The E288K colon tumor variant of DNA polymerase b is a sequence specific mutator
    • Murphy DL, Donigan KA, Jaeger J, Sweasy JB. 2012. The E288K colon tumor variant of DNA polymerase b is a sequence specific mutator. Biochemistry 51: 5269-5275.
    • (2012) Biochemistry , vol.51 , pp. 5269-5275
    • Murphy, D.L.1    Donigan, K.A.2    Jaeger, J.3    Sweasy, J.B.4
  • 111
    • 34547850642 scopus 로고    scopus 로고
    • Different structural states in oligonucleosomes are required for early versus late steps of base excision repair
    • Nakanishi S, Prasad R, Wilson SH, Smerdon M. 2007. Different structural states in oligonucleosomes are required for early versus late steps of base excision repair. Nucleic Acids Res 35: 4313-4321.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4313-4321
    • Nakanishi, S.1    Prasad, R.2    Wilson, S.H.3    Smerdon, M.4
  • 113
    • 84863614548 scopus 로고    scopus 로고
    • Colon cancer-associated DNA polymerase b variant induces genomic instability and cellular transformation
    • Nemec AA, Donigan KA, Murphy DL, Jaeger J, Sweasy JB. 2012. Colon cancer-associated DNA polymerase b variant induces genomic instability and cellular transformation. J Biol Chem 287: 23840-23849.
    • (2012) J Biol Chem , vol.287 , pp. 23840-23849
    • Nemec, A.A.1    Donigan, K.A.2    Murphy, D.L.3    Jaeger, J.4    Sweasy, J.B.5
  • 114
    • 3242876769 scopus 로고    scopus 로고
    • Sibling rivalry: Competition between Pol X family members in V(D)J recombination and general double strand break repair
    • Nick McElhinny SA, Ramsden DA. 2004. Sibling rivalry: Competition between Pol X family members in V(D)J recombination and general double strand break repair. Immunol Rev 200: 156-164.
    • (2004) Immunol Rev , vol.200 , pp. 156-164
    • Nick McElhinny, S.A.1    Ramsden, D.A.2
  • 115
    • 0030841051 scopus 로고    scopus 로고
    • Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
    • Nilsen H, Otterlei M, Haug T, Solum K, Nagelhus TA, Skorpen F, Krokan HE. 1997. Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. Nucleic Acids Res 25: 750-755.
    • (1997) Nucleic Acids Res , vol.25 , pp. 750-755
    • Nilsen, H.1    Otterlei, M.2    Haug, T.3    Solum, K.4    Nagelhus, T.A.5    Skorpen, F.6    Krokan, H.E.7
  • 117
    • 3042686671 scopus 로고    scopus 로고
    • The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site
    • O'Brien PJ, Ellenberger T. 2004. The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site. J Biol Chem 279: 26876-26884.
    • (2004) J Biol Chem , vol.279 , pp. 26876-26884
    • O'Brien, P.J.1    Ellenberger, T.2
  • 118
    • 84868035470 scopus 로고    scopus 로고
    • Rules of engagement for base excision repair in chromatin
    • Odell ID, Wallace SS, Pederson DS. 2013. Rules of engagement for base excision repair in chromatin. J Cell Physiol 228: 258-266.
    • (2013) J Cell Physiol , vol.228 , pp. 258-266
    • Odell, I.D.1    Wallace, S.S.2    Pederson, D.S.3
  • 120
    • 17444364433 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts
    • Parsons JL, Dianova, II, Allinson SL, Dianov GL. 2005a. Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts. FEBS J 272: 2012-2021.
    • (2005) FEBS J , vol.272 , pp. 2012-2021
    • Parsons, J.L.1    Dianova, I.I.2    Allinson, S.L.3    Dianov, G.L.4
  • 121
    • 24044523891 scopus 로고    scopus 로고
    • ' end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1
    • ' end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1. Nucleic Acids Res 33: 4849- 4856.
    • (2005) Nucleic Acids Res , vol.33 , pp. 4849
    • Parsons, J.L.1    Zharkov, D.O.2    Dianov, G.L.3
  • 122
    • 34047213485 scopus 로고    scopus 로고
    • NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break
    • Parsons JL, Kavli B, Slupphaug G, Dianov GL. 2007. NEIL1 is the major DNA glycosylase that processes 5-hydroxyuracil in the proximity of a DNA single-strand break. Biochemistry 46: 4158-4163.
    • (2007) Biochemistry , vol.46 , pp. 4158-4163
    • Parsons, J.L.1    Kavli, B.2    Slupphaug, G.3    Dianov, G.L.4
  • 124
    • 34547645005 scopus 로고    scopus 로고
    • Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms
    • Pettersen HS, Sundheim O, Gilljam KM, Slupphaug G, Krokan HE, Kavli B. 2007. Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms. Nucleic Acids Res 35: 3879-3892.
    • (2007) Nucleic Acids Res , vol.35 , pp. 3879-3892
    • Pettersen, H.S.1    Sundheim, O.2    Gilljam, K.M.3    Slupphaug, G.4    Krokan, H.E.5    Kavli, B.6
  • 125
    • 80455155967 scopus 로고    scopus 로고
    • UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation
    • Pettersen HS, Visnes T, Vagbo CB, Svaasand EK, Doseth B, Slupphaug G, Kavli B, Krokan HE. 2011. UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. Nucleic Acids Res 39: 8430-8444.
    • (2011) Nucleic Acids Res , vol.39 , pp. 8430-8444
    • Pettersen, H.S.1    Visnes, T.2    Vagbo, C.B.3    Svaasand, E.K.4    Doseth, B.5    Slupphaug, G.6    Kavli, B.7    Krokan, H.E.8
  • 127
    • 0037108463 scopus 로고    scopus 로고
    • Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
    • Rada C, Williams GT, Nilsen H, Barnes DE, Lindahl T, Neuberger MS. 2002. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr Biol 12: 1748-1755.
    • (2002) Curr Biol , vol.12 , pp. 1748-1755
    • Rada, C.1    Williams, G.T.2    Nilsen, H.3    Barnes, D.E.4    Lindahl, T.5    Neuberger, M.S.6
  • 128
    • 0030816108 scopus 로고    scopus 로고
    • Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
    • Radicella JP, Dherin C, Desmaze C, Fox MS, Boiteux S. 1997. Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. Proc Natl Acad Sci 94: 8010-8015.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 8010-8015
    • Radicella, J.P.1    Dherin, C.2    Desmaze, C.3    Fox, M.S.4    Boiteux, S.5
  • 129
    • 34247862129 scopus 로고    scopus 로고
    • Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations
    • Radom CT, Banerjee A, Verdine GL. 2007. Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J Biol Chem 282: 9182-9194.
    • (2007) J Biol Chem , vol.282 , pp. 9182-9194
    • Radom, C.T.1    Banerjee, A.2    Verdine, G.L.3
  • 131
    • 62349120246 scopus 로고    scopus 로고
    • DNA repair in mammalian cells: Base excision repair: The long and short of it
    • Robertson AB, Klungland A, Rognes T, Leiros I. 2009. DNA repair in mammalian cells: Base excision repair: The long and short of it. Cell Mol Life Sci 66: 981-993.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 981-993
    • Robertson, A.B.1    Klungland, A.2    Rognes, T.3    Leiros, I.4
  • 133
    • 48149114323 scopus 로고    scopus 로고
    • Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains
    • Rolseth V, Runden-Pran E, Luna L, McMurray C, Bjoras M, Ottersen OP. 2008. Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains. DNA Repair (Amst) 7: 1578-1588.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1578-1588
    • Rolseth, V.1    Runden-Pran, E.2    Luna, L.3    McMurray, C.4    Bjoras, M.5    Ottersen, O.P.6
  • 134
    • 0030738194 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase
    • Rosenquist TA, Zharkov DO, Grollman AP. 1997. Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. Proc Natl Acad Sci 94: 7429-7434.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 7429-7434
    • Rosenquist, T.A.1    Zharkov, D.O.2    Grollman, A.P.3
  • 135
    • 46649086715 scopus 로고    scopus 로고
    • A new protein architecture for processing alkylation damaged DNA: The crystal structure of DNA glycosylase AlkD
    • Rubinson EH, Metz AH, O'Quin J, Eichman BF. 2008. A new protein architecture for processing alkylation damaged DNA: The crystal structure of DNA glycosylase AlkD. J Mol Biol 381: 13-23.
    • (2008) J Mol Biol , vol.381 , pp. 13-23
    • Rubinson, E.H.1    Metz, A.H.2    O'Quin, J.3    Eichman, B.F.4
  • 137
    • 65249161710 scopus 로고    scopus 로고
    • Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation
    • Schanz S, Castor D, Fischer F, Jiricny J. 2009. Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation. Proc Natl Acad Sci 106: 5593-5598.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 5593-5598
    • Schanz, S.1    Castor, D.2    Fischer, F.3    Jiricny, J.4
  • 141
    • 4944235161 scopus 로고    scopus 로고
    • Exchangeability of mammalian DNA ligases between base excision repair pathways
    • Sleeth KM, Robson RL, Dianov GL. 2004. Exchangeability of mammalian DNA ligases between base excision repair pathways. Biochemistry 43: 12924-12930.
    • (2004) Biochemistry , vol.43 , pp. 12924-12930
    • Sleeth, K.M.1    Robson, R.L.2    Dianov, G.L.3
  • 142
    • 0029904839 scopus 로고    scopus 로고
    • A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
    • Slupphaug G, Mol CD, Kavli B, Arvai AS, Krokan HE, Tainer JA. 1996. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature 384: 87-92.
    • (1996) Nature , vol.384 , pp. 87-92
    • Slupphaug, G.1    Mol, C.D.2    Kavli, B.3    Arvai, A.S.4    Krokan, H.E.5    Tainer, J.A.6
  • 143
    • 0035225929 scopus 로고    scopus 로고
    • Mammalian DNA b-polymerase in base excision repair of alkylation damage
    • Sobol RW, Wilson SH. 2001. Mammalian DNA b-polymerase in base excision repair of alkylation damage. Prog Nucleic Acid Res Mol Biol 68: 57-74.
    • (2001) Prog Nucleic Acid Res Mol Biol , vol.68 , pp. 57-74
    • Sobol, R.W.1    Wilson, S.H.2
  • 146
    • 13944279514 scopus 로고    scopus 로고
    • Is there a link between DNA polymerase b and cancer?
    • Starcevic D, Dalal S, Sweasy JB. 2004. Is there a link between DNA polymerase b and cancer? Cell Cycle 3: 998-1001.
    • (2004) Cell Cycle , vol.3 , pp. 998-1001
    • Starcevic, D.1    Dalal, S.2    Sweasy, J.B.3
  • 147
    • 79955632686 scopus 로고    scopus 로고
    • Complex regulation and function of activation-induced cytidine deaminase
    • Stavnezer J. 2011. Complex regulation and function of activation-induced cytidine deaminase. Trends Immunol 32: 194-201.
    • (2011) Trends Immunol , vol.32 , pp. 194-201
    • Stavnezer, J.1
  • 148
    • 0033568311 scopus 로고    scopus 로고
    • Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts
    • Stierum RH, Dianov GL, Bohr VA. 1999. Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts. Nucleic Acids Res 27: 3712-3719.
    • (1999) Nucleic Acids Res , vol.27 , pp. 3712-3719
    • Stierum, R.H.1    Dianov, G.L.2    Bohr, V.A.3
  • 149
    • 38849207616 scopus 로고    scopus 로고
    • Extrahelical damaged base recognition by DNA glycosylase enzymes
    • Stivers JT. 2008. Extrahelical damaged base recognition by DNA glycosylase enzymes. Chemistry 14: 786-793.
    • (2008) Chemistry , vol.14 , pp. 786-793
    • Stivers, J.T.1
  • 150
    • 0035580975 scopus 로고    scopus 로고
    • Uracil DNA glycosylase: Insights from a master catalyst
    • Stivers JT, Drohat AC. 2001. Uracil DNA glycosylase: Insights from a master catalyst. Arch Biochem Biophys 396: 1-9.
    • (2001) Arch Biochem Biophys , vol.396 , pp. 1-9
    • Stivers, J.T.1    Drohat, A.C.2
  • 151
    • 79955588797 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate
    • Strom CE, Johansson F, Uhlen M, Szigyarto CA, Erixon K, Helleday T. 2011. Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate. Nucleic Acids Res 39: 3166-3175.
    • (2011) Nucleic Acids Res , vol.39 , pp. 3166-3175
    • Strom, C.E.1    Johansson, F.2    Uhlen, M.3    Szigyarto, C.A.4    Erixon, K.5    Helleday, T.6
  • 152
    • 0034254724 scopus 로고    scopus 로고
    • Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8
    • Sugahara M, Mikawa T, Kumasaka T, Yamamoto M, Kato R, Fukuyama K, Inoue Y, Kuramitsu S. 2000. Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8. EMBO J 19: 3857-3869.
    • (2000) EMBO J , vol.19 , pp. 3857-3869
    • Sugahara, M.1    Mikawa, T.2    Kumasaka, T.3    Yamamoto, M.4    Kato, R.5    Fukuyama, K.6    Inoue, Y.7    Kuramitsu, S.8
  • 154
    • 79957456954 scopus 로고    scopus 로고
    • Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage
    • Svilar D, Goellner EM, Almeida KH, Sobol RW. 2011. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxid Redox Signal 14: 2491-2507.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 2491-2507
    • Svilar, D.1    Goellner, E.M.2    Almeida, K.H.3    Sobol, R.W.4
  • 155
    • 55049124777 scopus 로고    scopus 로고
    • Long patch base excision repair in mammalian mitochondrial genomes
    • Szczesny B, Tann AW, Longley MJ, Copeland WC, Mitra S. 2008. Long patch base excision repair in mammalian mitochondrial genomes. J Biol Chem 283: 26349-26356.
    • (2008) J Biol Chem , vol.283 , pp. 26349-26356
    • Szczesny, B.1    Tann, A.W.2    Longley, M.J.3    Copeland, W.C.4    Mitra, S.5
  • 156
  • 161
    • 34447323281 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy
    • 6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy. DNA Repair (Amst) 6: 1100-1115.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 1100-1115
    • Tubbs, J.L.1    Pegg, A.E.2    Tainer, J.A.3
  • 163
    • 53149103171 scopus 로고    scopus 로고
    • The rate of base excision repair of uracil is controlled by the initiating glycosylase
    • Visnes T, Akbari M, Hagen L, Slupphaug G, Krokan HE. 2008. The rate of base excision repair of uracil is controlled by the initiating glycosylase. DNA Repair (Amst) 7: 1869-1881.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1869-1881
    • Visnes, T.1    Akbari, M.2    Hagen, L.3    Slupphaug, G.4    Krokan, H.E.5
  • 165
    • 0026671855 scopus 로고
    • DNA polymerase beta mutations in human colorectal cancer
    • Wang L, Patel U, Ghosh L, Banerjee S. 1992. DNA polymerase beta mutations in human colorectal cancer. Cancer Res 52: 4824-4827.
    • (1992) Cancer Res , vol.52 , pp. 4824-4827
    • Wang, L.1    Patel, U.2    Ghosh, L.3    Banerjee, S.4
  • 167
    • 0032534053 scopus 로고    scopus 로고
    • Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA
    • Williams SD, David SS. 1998. Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA. Nucleic Acids Res 26: 5123-5133.
    • (1998) Nucleic Acids Res , vol.26 , pp. 5123-5133
    • Williams, S.D.1    David, S.S.2
  • 169
    • 43849110460 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks
    • Woodhouse BC, Dianova II, Parsons JL, Dianov GL. 2008. Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks. DNA Repair (Amst) 7: 932-940.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 932-940
    • Woodhouse, B.C.1    Dianova, I.I.2    Parsons, J.L.3    Dianov, G.L.4
  • 170
    • 2342520175 scopus 로고    scopus 로고
    • Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
    • Xie Y, Yang H, Cunanan C, Okamoto K, Shibata D, Pan J, Barnes DE, Lindahl T, McIlhatton M, Fishel R, et al. 2004. Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res 64: 3096- 3102.
    • (2004) Cancer Res , vol.64 , pp. 3096
    • Xie, Y.1    Yang, H.2    Cunanan, C.3    Okamoto, K.4    Shibata, D.5    Pan, J.6    Barnes, D.E.7    Lindahl, T.8    McIlhatton, M.9    Fishel, R.10
  • 171
    • 42549128712 scopus 로고    scopus 로고
    • Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
    • Yang CG, Yi C, Duguid EM, Sullivan CT, Jian X, Rice PA, He C. 2008. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature 452: 961-965.
    • (2008) Nature , vol.452 , pp. 961-965
    • Yang, C.G.1    Yi, C.2    Duguid, E.M.3    Sullivan, C.T.4    Jian, X.5    Rice, P.A.6    He, C.7
  • 172
    • 77749252749 scopus 로고    scopus 로고
    • Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts
    • Zhao X, Krishnamurthy N, Burrows CJ, David SS. 2010. Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts. Biochemistry 49: 1658-1666.
    • (2010) Biochemistry , vol.49 , pp. 1658-1666
    • Zhao, X.1    Krishnamurthy, N.2    Burrows, C.J.3    David, S.S.4
  • 173
    • 55049112210 scopus 로고    scopus 로고
    • Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates
    • Zheng L, Zhou M, Guo Z, Lu H, Qian L, Dai H, Qiu J, Yakubovskaya E, Bogenhagen DF, Demple B, et al. 2008. Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates. Mol Cell 32: 325-336.
    • (2008) Mol Cell , vol.32 , pp. 325-336
    • Zheng, L.1    Zhou, M.2    Guo, Z.3    Lu, H.4    Qian, L.5    Dai, H.6    Qiu, J.7    Yakubovskaya, E.8    Bogenhagen, D.F.9    Demple, B.10


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