Rev1 and Polζ influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent

DNA Repair

Volumn 7, Issue 3, 2008, Pages 431-438

  Monti, Paola ^a   Ciribilli, Yari ^a   Russo, Debora ^a   Bisio, Alessandra ^a   Perfumo, Chiara ^a   Andreotti, Virginia ^a   Menichini, Paola ^a   Inga, Alberto ^a   Huang, Xiaofen ^b   Gold, Barry ^b   Fronza, Gilberto ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Me lex; N3 methyladenine; p53; Translesion synthesis; Yeast

Indexed keywords

3 METHYLADENINE; [1 METHYL 4 [1 METHYL 4 (3 METHOXYSULFONYLPROPANAMIDO)PYRROLE 2 CARBOXAMIDO]PYRROLE 2 CARBOXAMIDO]PROPANE; DNA POLYMERASE; DNA POLYMERASE REV1; DNA POLYMERASE REV3; DNA POLYMERASE ZETA; PROPIONAMIDE DERIVATIVE; PROTEIN P53; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE; ANTIMUTAGENIC AGENT; APN1 PROTEIN, S CEREVISIAE; APN2 PROTEIN, S CEREVISIAE; CONGOCIDINE; DEOXYRIBONUCLEASE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA DIRECTED DNA POLYMERASE; DNA GLYCOSYLTRANSFERASE; DRUG DERIVATIVE; MAG1 PROTEIN, S CEREVISIAE; METHYL LEXITROPSIN; MUTAGENIC AGENT; NUCLEOTIDYLTRANSFERASE; RAD14 PROTEIN, S CEREVISIAE; REV1 PROTEIN, S CEREVISIAE; REV3 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CENTROMERE; CONTROLLED STUDY; ENZYME ACTIVE SITE; EXCISION REPAIR; EXPRESSION VECTOR; FUNGAL GENE; FUNGAL STRAIN; GENE CONTROL; GENE DELETION; MUTAGENICITY; NONHUMAN; PLASMID; PRIORITY JOURNAL; REPORTER GENE; SACCHAROMYCES CEREVISIAE; STRAIN DIFFERENCE; TOXICITY; WILD TYPE; CELL SURVIVAL; CHEMISTRY; DNA METHYLATION; DNA REPAIR; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY;

ADENINE; ANTIMUTAGENIC AGENTS; CELL SURVIVAL; DNA GLYCOSYLASES; DNA METHYLATION; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-DIRECTED DNA POLYMERASE; ENDODEOXYRIBONUCLEASES; MUTAGENS; NETROPSIN; NUCLEOTIDYLTRANSFERASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 39149145145     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2007.11.015     Document Type: Article

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