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Volumn 16, Issue 20, 1997, Pages 6314-6322

Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites

Author keywords

8 oxoguanine; AP lyase; Base excision; DNA glycosylase; DNA repair

Indexed keywords

DNA GLYCOSYLTRANSFERASE; GREEN FLUORESCENT PROTEIN; GUANINE DERIVATIVE;

EID: 0030703177     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.20.6314     Document Type: Article
Times cited : (333)

References (47)
  • 4
    • 0027171181 scopus 로고
    • Evidence for two DNA repair enzymes for 8-hydroxyguanine (7.8-dihydro-8-oxoguanine) in human cells
    • Bessho,T. Tano,K., Kasai,H., Ohtsuka,E.. and Nishimura,N. (1993a) Evidence for two DNA repair enzymes for 8-hydroxyguanine (7.8-dihydro-8-oxoguanine) in human cells. J. Biol. Chem., 268. 19416-19421.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19416-19421
    • Bessho, T.1    Tano, K.2    Kasai, H.3    Ohtsuka, E.4    Nishimura, N.5
  • 7
    • 0027250070 scopus 로고
    • Properties and biological functions of the NTH and FPG proteins of Escherichia call: Two DNA glycosylascs that repair oxidative DNA damage
    • Boileux,S. (1993) Properties and biological functions of the NTH and FPG proteins of Escherichia call: two DNA glycosylascs that repair oxidative DNA damage. J. Photochem. Photobiol., 19, 87-96.
    • (1993) J. Photochem. Photobiol. , vol.19 , pp. 87-96
    • Boileux, S.1
  • 8
    • 0020672349 scopus 로고
    • Imidazole open ring 7-mcthylguaninc: An inhibitor of DNA synthesis
    • Boiteux,S. and Laval, J. (1983) Imidazole open ring 7-mcthylguaninc: an inhibitor of DNA synthesis. Biochem. Biophys. Res. Commun. 110, 552-558.
    • (1983) Biochem. Biophys. Res. Commun. , vol.110 , pp. 552-558
    • Boiteux, S.1    Laval, J.2
  • 9
    • 0021760535 scopus 로고
    • Two numeric forms of open ring 7-mcthylguaninc are present in alkylated polynucleotides
    • Boileux,S., Belleney,J., Roques,B.P. and Laval,J. (1984) Two numeric forms of open ring 7-mcthylguaninc are present in alkylated polynucleotides. Nucleic Acids Res., 12, 5429-5439.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 5429-5439
    • Boileux, S.1    Belleney, J.2    Roques, B.P.3    Laval, J.4
  • 10
    • 0023433565 scopus 로고
    • FormamidopyrimidineDNA glycosylase of Escherichia coli: Cloning and sequencing of the fpg structural gene and overproduction of the protein
    • Boiteux,S., O'Connor,T.R. and Laval,J. (1987) FormamidopyrimidineDNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein. EMBO J., 6. 3177-3183.
    • (1987) EMBO J. , vol.6 , pp. 3177-3183
    • Boiteux, S.1    O'Connor, T.R.2    Laval, J.3
  • 11
    • 0026533905 scopus 로고
    • Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization
    • Boiteux,S., Gajewski,J., Laval,J. and Dizdaroglu,M. (1992) Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry, 31, 106-110.
    • (1992) Biochemistry , vol.31 , pp. 106-110
    • Boiteux, S.1    Gajewski, J.2    Laval, J.3    Dizdaroglu, M.4
  • 12
    • 0026592966 scopus 로고
    • 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G T and AC substitutions
    • Cheng,K.C. Cahill,D.S., Kasai,H., Nishimura,S. and Loeb,L.A. (1992) 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G T and AC substitutions. J. Biol. Chem., 267, 166-172.
    • (1992) J. Biol. Chem. , vol.267 , pp. 166-172
    • Cheng, K.C.1    Cahill, D.S.2    Kasai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 13
    • 0028342951 scopus 로고
    • Repair of oxidativc damage to DNA: Enzymology and biology
    • Demple,B. and Harrison,L. (1994) Repair of oxidativc damage to DNA: enzymology and biology. Annu. Rev. Biochem., 63, 915-948.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 915-948
    • Demple, B.1    Harrison, L.2
  • 14
    • 0027301692 scopus 로고
    • Evidence for an imino intermediate in the T4 endonuclease V reaction
    • Dodson,M.L., Schrock,R.D. and Lloyd,S. (1993) Evidence for an imino intermediate in the T4 endonuclease V reaction. Biochemistry. 32. 8284-8290
    • (1993) Biochemistry , vol.32 , pp. 8284-8290
    • Dodson, M.L.1    Schrock, R.D.2    Lloyd, S.3
  • 15
    • 0028604549 scopus 로고
    • Unified catalytic mechanism for DNA glycosylases
    • Dodson,M.L., Michaels,M.L. and Lloyd,R.S. (1994) Unified catalytic mechanism for DNA glycosylases. J. Biol. Chem., 269, 32709-32712.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32709-32712
    • Dodson, M.L.1    Michaels, M.L.2    Lloyd, R.S.3
  • 16
    • 0029743301 scopus 로고    scopus 로고
    • Base excision of oxidative purine and pyrimidine DNA damage by a DNA glycosylase from yeast whose sequence is similar to endonuclease III from E. coli
    • Eide,L., Pirovano,M., Bjørås,M., Alscth,I., Berdal,K.G. and Seeberg,E.. (1996) Base excision of oxidative purine and pyrimidine DNA damage by a DNA glycosylase from yeast whose sequence is similar to endonuclease III from E. coli. Proc. Natl Acad. Sci. USA, 93. 10735-10740.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 10735-10740
    • Eide, L.1    Pirovano, M.2    Bjørås, M.3    Alscth, I.4    Berdal, K.G.5    Seeberg, E.6
  • 17
    • 0026499118 scopus 로고
    • Atomic structure of the DNA repair 4Fc-4S| enzyme endonuclease III
    • Fisher,C.L., O'Handley,S.F., Cunningham,R.P. and Tainer,J.A. (1992) Atomic structure of the DNA repair [4Fc-4S| enzyme endonuclease III. Science. 258, 434-440.
    • (1992) Science , vol.258 , pp. 434-440
    • Fisher, C.L.1    O'Handley, S.F.2    Cunningham, R.P.3    Tainer, J.A.4
  • 18
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2-deoxyguanosine in rat organ DNA and urine
    • Fraga,C.G., Shigenaga.M.K., Park,J.W. and Ames,B.N. (1990) Oxidative damage to DNA during aging: 8-hydroxy-2-deoxyguanosine in rat organ DNA and urine. Proc. Nail Acad. Sci. USA, 87, 4533-4537.
    • (1990) Proc. Nail Acad. Sci. USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.W.3    Ames, B.N.4
  • 19
    • 0027324378 scopus 로고
    • Mulagenesis by 8-oxoguanine: An enemy within
    • Grollman,A.P. and Moriya,M. (1993) Mulagenesis by 8-oxoguanine: an enemy within. Trends Genet., 9, 246-249.
    • (1993) Trends Genet. , vol.9 , pp. 246-249
    • Grollman, A.P.1    Moriya, M.2
  • 20
    • 0029125761 scopus 로고
    • Human calcium-calmodulin dependent protein kinase I: CDNA cloning. domain structure and activation by phosphorylation at thrconine-177 by calcium-calmodulin dependent protein kinase I kinase
    • Haribabu,B., Hook,S.S., Selbert,M.A., Goldstein,E..G., Tomhave,E..D., Edelman,A.M., Snyderman,R. and Means,A.R. (1995) Human calcium-calmodulin dependent protein kinase I: cDNA cloning. domain structure and activation by phosphorylation at thrconine-177 by calcium-calmodulin dependent protein kinase I kinase. EMBO J., 14, 3679-3686.
    • (1995) EMBO J. , vol.14 , pp. 3679-3686
    • Haribabu, B.1    Hook, S.S.2    Selbert, M.A.3    Goldstein, E.G.4    Tomhave, E.D.5    Edelman, A.M.6    Snyderman, R.7    Means, A.R.8
  • 21
    • 0023905646 scopus 로고
    • Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro
    • Imlay,J.A., Chin,S.M. and Linn.S. (1988) Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro. Science. 240. 640-642.
    • (1988) Science , vol.240 , pp. 640-642
    • Imlay, J.A.1    Chin, S.M.2    Linn, S.3
  • 22
    • 0002738322 scopus 로고
    • Formation of 8-hydroxydeoxyguanosine in DNA by oxygen radicals and its biological significance
    • Sies,H. (ed.) Academic Press, London, UK
    • Kasai,H. and Nishimura,S. (1991) Formation of 8-hydroxydeoxyguanosine in DNA by oxygen radicals and its biological significance. In Sies,H. (ed.) Oxidaiive Stress: Oxidants and Antioxidants. Academic Press, London, UK, pp. 99-116.
    • (1991) Oxidaiive Stress: Oxidants and Antioxidants , pp. 99-116
    • Kasai, H.1    Nishimura, S.2
  • 23
    • 0022809670 scopus 로고
    • Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair
    • Kasai,H., Crain,P.F., Kuchino,Y., Nishimura,S., Ootsuyama,A. and Tanooka,H. (1986) Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis.7, 1849-1851.
    • (1986) Carcinogenesis. , vol.7 , pp. 1849-1851
    • Kasai, H.1    Crain, P.F.2    Kuchino, Y.3    Nishimura, S.4    Ootsuyama, A.5    Tanooka, H.6
  • 26
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindaht,T. (1993) Instability and decay of the primary structure of DNA. Nature, 362, 709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindaht, T.1
  • 27
    • 0026513966 scopus 로고
    • MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
    • Maki,H. and Sekiguchi,M. (1992) MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. Nature. 355,273-275.
    • (1992) Nature , vol.355 , pp. 273-275
    • Maki, H.1    Sekiguchi, M.2
  • 29
    • 0026701365 scopus 로고
    • The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine 7.8-dihydm-8-oxoguanine
    • Michaels,M.L. and Miller,J.H. (1992) The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7.8-dihydm-8-oxoguanine. J. Bacteriol., 174, 6321-6325.
    • (1992) J. Bacteriol. , vol.174 , pp. 6321-6325
    • Michaels, M.L.1    Miller, J.H.2
  • 30
    • 0025301064 scopus 로고
    • MutY. an adenine glycosylase active on G-A mispairs, has homology to endonuclease III
    • Michaels,M.L., Pham,L., Nghiem.Y., Cruz,C. and Miller,J.H. (1990) MutY. an adenine glycosylase active on G-A mispairs, has homology to endonuclease III. Nucleic Acids Res., 18, 3841-3845.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3841-3845
    • Michaels, M.L.1    Pham, L.2    Nghiem, Y.3    Cruz, C.4    Miller, J.H.5
  • 31
    • 0026684849 scopus 로고
    • Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA
    • Michaels,M.L., Cruz,C., Grollman,A.P. and Miller,J.H. (1992) Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA. Proc. Natl Acad. Sci. USA, 89. 7022-7025.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7022-7025
    • Michaels, M.L.1    Cruz, C.2    Grollman, A.P.3    Miller, J.H.4
  • 32
    • 0025802822 scopus 로고
    • Site-specific mutagenesis using a gapped duplex vector: A study of translesion synthesis past 8-oxodeoxyguanosine in E. coli
    • Moriya,M., Ou.C., Bodepudi,V., Johnson,F., Takeshita,M. and Grollman,A.P. (1991 ) Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli. Mutat. Res., 254, 281-288.
    • (1991) Mutat. Res. , vol.254 , pp. 281-288
    • Moriya, M.1    Ou, C.2    Bodepudi, V.3    Johnson, F.4    Takeshita, M.5    Grollman, A.P.6
  • 33
    • 0027105007 scopus 로고
    • A knowledge base for predicting protein localization sites in eukaryotic cells
    • Nakai,K. and Kanehisa,M. (1992) A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics. 14, 897-911.
    • (1992) Genomics , vol.14 , pp. 897-911
    • Nakai, K.1    Kanehisa, M.2
  • 34
    • 0030220956 scopus 로고    scopus 로고
    • Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision repair protein superfamily
    • Nash,H., Bruner,S.D., Scharer,O.D., Kawate,T., Addona,T.A., Spooner,E.., Lane,W.S. and Verdine,G. (1996) Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision repair protein superfamily. Curr. Biol., 6, 968-980.
    • (1996) Curr. Biol. , vol.6 , pp. 968-980
    • Nash, H.1    Bruner, S.D.2    Scharer, O.D.3    Kawate, T.4    Addona, T.A.5    Spooner, E.6    Lane, W.S.7    Verdine, G.8
  • 35
    • 0030841051 scopus 로고    scopus 로고
    • Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
    • Nilsen,H., Ottcrlei,M., Haug,T., Solum,K., Nagclhus,T.A., Skorpen,F. and Krokan,H. (1997) Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. Nucleic Acids Res., 25, 750-755.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 750-755
    • Nilsen, H.1    Ottcrlei, M.2    Haug, T.3    Solum, K.4    Nagclhus, T.A.5    Skorpen, F.6    Krokan, H.7
  • 36
    • 0027368923 scopus 로고
    • Cloning and expression of cDNA for a human enzyme that hydrolyzcs 8-oxodGTP, a mutagenic substrate for DNA synthesis
    • Sakumi,K., Furuichi,M., Tsuzuki,T., Kakuma,J., Kawahata,S., Maki,H. and Sekiguchi,M. (1993) Cloning and expression of cDNA for a human enzyme that hydrolyzcs 8-oxodGTP, a mutagenic substrate for DNA synthesis. J. Biol. Chem., 268, 23524-23530.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23524-23530
    • Sakumi, K.1    Furuichi, M.2    Tsuzuki, T.3    Kakuma, J.4    Kawahata, S.5    Maki, H.6    Sekiguchi, M.7
  • 39
    • 0025981359 scopus 로고
    • Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxoG
    • Shibutani,S., Takeshita,M. and Grollman,A.P. (1991) Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxoG. Nature, 349, 431-434.
    • (1991) Nature , vol.349 , pp. 431-434
    • Shibutani, S.1    Takeshita, M.2    Grollman, A.P.3
  • 40
    • 0030004207 scopus 로고    scopus 로고
    • Cloning and sequencing a human homolog (nMYH) of the Escherichia roll MutY gene whose function is required for the repair of oxidative DNA damage
    • Slupska,M.M., Baikalov,C., Luther,W.M., Chiang,J.-H., Wei,Y.-F. and Miller,J.H. (1996) Cloning and sequencing a human homolog (nMYH) of the Escherichia roll MutY gene whose function is required for the repair of oxidative DNA damage. J. Bacterial., 178, 3885-3892.
    • (1996) J. Bacterial. , vol.178 , pp. 3885-3892
    • Slupska, M.M.1    Baikalov, C.2    Luther, W.M.3    Chiang, J.-H.4    Wei, Y.-F.5    Miller, J.H.6
  • 41
    • 0028933674 scopus 로고
    • Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guaninc nuclcotidc in Escherichia coli
    • Tajiri,T., Maki,H. and Sekiguchi,M. (1995) Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guaninc nuclcotidc in Escherichia coli. Mutat. Res., 336, 257-267.
    • (1995) Mutat. Res. , vol.336 , pp. 257-267
    • Tajiri, T.1    Maki, H.2    Sekiguchi, M.3
  • 42
    • 0027528412 scopus 로고
    • Repair of DNA containing the oxidativelv-damagcd base, 8-oxoguaninc
    • Tchou,J. and Grollman,A.P. (1993) Repair of DNA containing the oxidativelv-damagcd base, 8-oxoguaninc. Mutation Res., 299, 277-287.
    • (1993) Mutation Res. , vol.299 , pp. 277-287
    • Tchou, J.1    Grollman, A.P.2
  • 44
    • 0029119097 scopus 로고
    • Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure
    • Thayer,M.M., Ahern,H., Xing,D., Cunningham,R.P. and Tainer,J.A. (1995) Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure. EMBO J., 14, 4108-4120.
    • (1995) EMBO J. , vol.14 , pp. 4108-4120
    • Thayer, M.M.1    Ahern, H.2    Xing, D.3    Cunningham, R.P.4    Tainer, J.A.5
  • 45
    • 0029896229 scopus 로고    scopus 로고
    • Cloning and expression in Escherichia coli of the OGGI gene of Saccharomyces cerrvisiae, which encodes a DNA glycosylase that excises 7.8-dihydro-8-oxoguanine and 2.6-diamino-4-hydroxy-5-N-methylformamidopyrimidine
    • van der Kemp,P.A., Thomas,D., Barbey,K., de Oliveira,R. and Boiteux,S. (1996) Cloning and expression in Escherichia coli of the OGGI gene of Saccharomyces cerrvisiae, which encodes a DNA glycosylase that excises 7.8-dihydro-8-oxoguanine and 2.6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. Proc. Natl Acad. Sci. USA, 93, 5197-5202.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 5197-5202
    • Van der Kemp, P.A.1    Thomas, D.2    Barbey, K.3    De Oliveira, R.4    Boiteux, S.5
  • 46
    • 0025334691 scopus 로고
    • Mechanistic studies of ionizing radiation and oxidative mutagenesis: Genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome
    • Wood,M.L., Dizdaroglu,M., Gajcwski,E.. and Essigmann,J.M. (1990) Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. Biochemistry. 29, 7024-7032.
    • (1990) Biochemistry , vol.29 , pp. 7024-7032
    • Wood, M.L.1    Dizdaroglu, M.2    Gajcwski, E.3    Essigmann, J.M.4
  • 47
    • 16044372779 scopus 로고    scopus 로고
    • Three-dimensional structure of a DNA repair enzyme. 3-methyladenine DNA glycosylase II. from Escherichia coli
    • Yamagata,Y. et al. (1996) Three-dimensional structure of a DNA repair enzyme. 3-methyladenine DNA glycosylase II. from Escherichia coli. Cell. 86, 311-319.
    • (1996) Cell , vol.86 , pp. 311-319
    • Yamagata, Y.1


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