Uracil in DNA - Occurrence, consequences and repair

Oncogene

Volumn 21, Issue 58 REV. ISS. 8, 2002, Pages 8935-8948

  Krokan, Hans E ^a   Drabløs, Finn ^a   Slupphaug, Geir ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

DNA repair; Uracil; Uracil DNA glycosylase

Indexed keywords

ADENINE; DEAMINASE; DNA; DNA GLYCOSYLTRANSFERASE; FLUOROURACIL; GUANINE; IMMUNOGLOBULIN; PROTEIN MLH1; PROTEIN MSH2; SINGLE STRANDED DNA; THYMINE; URACIL;

AMINO ACID SUBSTITUTION; BASE MISPAIRING; BIODIVERSITY; CPG ISLAND; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; GENE MUTATION; GLYCOSYLATION; HUMAN; LIFESPAN; LYMPHOPROLIFERATIVE DISEASE; MOLECULAR EVOLUTION; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REVIEW; SITE DIRECTED MUTAGENESIS;

BASE PAIR MISMATCH; CATALYTIC DOMAIN; DNA; DNA GLYCOSYLASES; DNA REPAIR; ENDODEOXYRIBONUCLEASES; EVOLUTION, MOLECULAR; HUMANS; N-GLYCOSYL HYDROLASES; THYMINE DNA GLYCOSYLASE; URACIL; URACIL-DNA GLYCOSIDASE;

EID: 0037115911     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205996     Document Type: Review

References (111)

1. Altschul SF, Gish W, Miller W, Myers EW and Lipman DJ. (1990). J. Mol. Biol., 215, 403-410.
2. Aravind L and Koonin EV. (2000). Genome Biol., 1, RESEARCH0007.
3. Baker D, Liu P, Burdzy A and Sowers LC. (2002). Chem. Res. Toxicol., 15, 33-39.
4. Barrett TE, Savva R, Panayotou G, Barlow T, Brown T, Jiricny J and Pearl LH. (1998). Cell, 92, 117-129.
5. Barrett TE, Scharer OD, Savva R, Brown T, Jiricny J, Verdine GL and Pearl LH. (1999). EMBO J., 18, 6599-6609.
6. Bartsch H and Nair J. (2000). Toxicology, 153, 105-114.
7. Basu AK, Wood ML, Niedernhofer LJ, Ramos LA and Essigmann JM. (1993). Biochemistry, 32, 12793-12801.
8. Bateman A, Birney E, Cerruti L, Durbin R, Etwiller L, Eddy SR, Griffiths-Jones S, Howe KL, Marshall M and Sonnhammer ELL. (2002). Nucleic Acids Res., 30, 276-280.
9. Bellacosa A. (2001). J. Cell Physiol., 187, 137-144.
10. Bellacosa A, Cicchillitti L, Schepis F, Riccio A, Yeung AT, Matsumoto Y, Golemis EA, Genuardi M and Neri G. (1999). Proc. Natl. Acad. Sci. USA, 96, 3969-3974.
11. Bellamy SR and Baldwin GS. (2001). Nucleic Acids Res., 29, 3857-3863.
12. Bennett SE, Sanderson RJ and Mosbaugh DW. (1995). Biochemistry, 34, 6109-6119.
13. Bharati S, Krokan HE, Kristiansen L, Otterlei M and Slupphaug G. (1998). Nucleic Acids Res., 26, 4953-4959.
14. Boorstein RJ, Cummings Jr A, Marenstein DR, Chan MK, Ma Y, Neubert TA, Brown SM and Teebor GW. (2001). J. Biol. Chem., 276, 41991-41997.
15. Boorstein RJ, Levy DD and Teebor GW. (1987). Mutat. Res., 183, 257-263.
16. Bouhamdan M, Benichou S, Rey F, Navarro JM, Agostini I, Spire B, Camonis J, Slupphaug G, Vigne R, Benarous R and Sire J. (1996). J. Virol., 70, 697-704.
17. Brown TC and Jiricny J. (1987). Cell, 50, 945-950.
18. Bruner SD, Norman DPG and Verdine GL. (2000). Nature, 403, 859-866.
19. Cannon Carlson SV, Gokhale H and Teebor GW. (1989). J. Biol. Chem., 264, 13306-13312.
20. Di Noia J and Neuberger MS. (2002). Nature, 419, 43-48.
21. Dinner AR, Blackburn GM and Karplus M. (2001). Nature, 413, 752-755.
22. Dogliotti E, Fortini P, Pascucci B and Parlanti E. (2001). Prog. Nucleic Acids Res. Mol. Biol., 68, 3-27.
23. Drohat AC, Xiao G, Tordova M, Jagadeesh J, Pankiewicz KW, Watanabe KA, Gilliland GL and Stivers JT. (1999). Biochemistry, 38, 11876-11886.
24. Eftedal I, Guddal PH, Slupphaug G, Volden G and Krokan HE. (1993). Nucleic Acids Res., 21, 2095-2101.
25. Eftedal I, Volden G and Krokan HE. (1994). Ann. NY Acad Sci., 726, 312-314.
26. Eisen JA and Hanawalt PC. (1999). Mutat. Res., 435, 171-213.
27. Faure H, Mousseau M, Cadet J, Guimier C, Tripier M, Hida H and Favier A. (1998). Free Radical Res., 28, 377-382.
28. Friedberg EC, Walker GC and Siede W. (1995). DNA Repair and Mutagenesis. Washington, DC: ASM Press. pp. 698.
29. Gruss A and Michel B. (2001). Curr. Opin. Microbiol., 4, 595-601.
30. Handa P, Roy S and Varshney U. (2001). J. Biol. Chem., 276, 17324-17331.
31. Hang B, Medina M, Fraenkel-Conrat H and Singer B. (1998). Proc. Natl. Acad. Sci. USA, 95, 13561-13566.
32. Haracska L, Johnson RE, Unk I, Phillips BB, Hurwitz J, Prakash L and Prakash S. (2001). Proc. Natl. Acad. Sci. USA, 98, 14256-14261.
33. Hardeland U, Bentele M, Jiricny J and Schar P. (2000). J. Biol. Chem., 275, 33449-33456.
34. Hardeland U, Bentele M, Lettieri T, Steinacher R, Jiricny J and Schar P. (2001). Prog. Nucleic Acids Res. Mol. Biol., 68, 235-253.
35. Hardeland U, Steinacher R, Jiricny J and Schar P. (2002). EMBO J., 21, 1456-1464.
36. Haug T, Skorpen F, Aas PA, Malm V, Skjelbred C and Krokan HE. (1998). Nucleic Acids Res., 26, 1449-1457.
37. Haushalter KA, Todd Stukenberg MW, Kirschner MW and Verdine GL. (1999). Curr. Biol., 9, 174-185.
38. Hendrich B and Bird A. (1998). Mol. Cell. Biol., 18, 6538-6547.
39. Hendrich B and Bird A. (2000). DNA Methylation and Cancer, 249, 55-74.
40. Hendrich B, Hardeland U, Ng HH, Jiricny J and Bird A. (1999). Nature, 401, 301-304.
41. Holm L and Sander C. (1993). J. Mol. Biol., 233, 123-138.
42. Horsfall MJ, Borden A and Lawrence CW. (1997). J. Bact., 179, 2835-2839.
43. Hubbard T, Barker D, Birney E, Cameron G, Chen Y, Clark L, Cox T, Cuff J, Curwen V, Down T, Durbin R, Eyras E, Gilbert J, Hammond M, Huminiecki L, Kasprzyk A, Lehvaslaiho H, Lijnzaad P, Melsopp C, Mongin E, Pettett R, Pocock M, Potter S, Rust A, Schmidt E, Searle S, Slater G, Smith J, Spooner W, Stabenau A, Stalker J, Stupka E, Ureta-Vidal A, Vastrik I and Clamp M. (2002). Nucleic Acids Res., 30, 38-41.
44. Jiang YL and Stivers JT. (2001). Biochemistry, 40, 7710-7719.
45. Kavli B, Slupphaug G, Mol CD, Arvai AS, Petersen SB, Tainer JA and Krokan HE. (1996). EMBO J., 15, 3442-3447.
46. Kavli B, Sundheim O, Akbari M, Otterlei M, Nilsen H, Skorpen F, Aas PA, Hagen L, Krokan HE and Slupphaug G. (2002). J. Biol. Chem. (In press). Electronic publication ahead of print, August 2, 2002.
47. Krokan HE, Otterlei M, Nilsen H, Kavli B, Skorpen F, Andersen S, Skjelbred C, Akbari M, Aas PA and Slupphaug G. (2001). Prog. Nucleic Acids Res. Mol. Biol., 68, 365-386.
48. Krokan HE, Standal R and Slupphaug G. (1997). Biochem. J., 325, 1-16.
49. Levy DD and Teebor GW. (1991). Nucleic Acids Res., 19, 3337-3343.
50. Lindahl T. (1974). Proc. Natl. Acad. Sci. USA, 71, 3649-3653.
51. Lindahl T. (1993). Nature, 362, 709-715.
52. Mellac S, Fazakerley GV and Sowers LC. (1993). Biochemistry, 32, 7779-7786.
53. Missero C, Pirro MT, Simeone S, Pischetola M and Di Lauro R. (2001). J. Biol. Chem., 276, 33569-33575.
54. Mol CD, Arvai AS, Begley TJ, Cunningham RP and Tainer JA. (2002). J. Mol. Biol., 315, 373-384.
55. Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE and Tainer JA. (1995). Cell, 80, 869-878.
56. Moriya M, Zhang W, Johnson F and Grollman AP. (1994). Proc. Natl. Acad. Sci. USA, 91, 11899-11903.
57. Muller S, Hoege C, Pyrowolakis G and Jentsch S. (2001). Nature Rev. Mol. Cell Biol., 2, 202-210.
58. Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y and Honjo T. (2000). Cell, 102, 553-563.
59. Muramatsu M, Sankaranand VS, Anant S, Sugai M, Kinoshita K, Davidson NO and Honjo T. (1999). J. Biol. Chem., 274, 18470-18476.
60. Neddermann P, Gallinari P, Lettieri T, Schmid D, Truong O, Hsuan JJ, Wiebauer K and Jiricny J. (1996). J. Biol. Chem., 271, 12767-12774.
61. Neddermann P and Jiricny J. (1993). J. Biol. Chem., 268, 21218-21224.
62. Nilsen H, Haushalter KA, Robins P, Barnes DE, Verdine GL and Lindahl T. (2001). EMBO J., 20, 4278-4286.
63. Nilsen H, Otterlei M, Haug T, Solum K, Nagelhus TA, Skorpen F and Krokan HE. (1997). Nucleic Acids Res., 25, 750-755.
64. Nilsen H, Rosewell I, Robins P, Skjelbred CF, Andersen S, Slupphaug G, Daly G, Krokan HE, Lindahl T and Barnes DE. (2000). Mol. Cell, 5, 1059-1065.
65. Nilsen H, Yazdankhah SP, Eftedal I and Krokan HE. (1995). FEBS Lett., 362, 205-209.
66. Olsen LC, Aasland R, Wittwer CU, Krokan HE and Helland DE. (1989). EMBO J., 8, 3121-3125.
67. Otterlei M, Haug T, Nagelhus TA, Slupphaug G, Lindmo T and Krokan HE. (1998). Nucleic Acids Res., 26, 4611-4617.
68. Otterlei M, Kavli B, Standal R, Skjelbred C, Bharati S and Krokan HE. (2000). EMBO J., 19, 5542-5551.
69. Otterlei M, Warbrick E, Nagelhus TA, Haug T, Slupphaug G, Akbari M, Aas PA, Steinsbekk K, Bakke O and Krokan HE. (1999). EMBO J., 18, 3834-3844.
70. Parikh SS, Mol CD, Slupphaug G, Bharati S, Krokan HE and Tainer JA. (1998). EMBO J., 17, 5214-5226.
71. Parikh SS, Putnam CD and Tainer JA. (2000a). Mutat. Res., 460, 183-199.
72. Parikh SS, Walcher G, Jones GD, Slupphaug G, Krokan HE, Blackburn GM and Tainer JA. (2000b). Proc. Natl. Acad. Sci. USA, 97, 5083-5088.
73. Pasternack LB, Bramham J, Mayol L, Galeone A, Jia X and Kearns DR. (1996). Nucleic Acids Res., 24, 2740-2745.
74. Pearl FMG, Lee D, Bray JE, Sillitoe I, Todd AE, Harrison AP, Thornton JM and Orengo CA. (2000). Nucleic Acids Res., 28, 277-282.
75. Pearl LH. (2000). Mutat. Res., 460, 165-181.
76. Petersen-Mahrt SK, Harris RS and Neuberger MS. (2002). Nature, 418, 99-103.
77. Petronzelli F, Riccio A, Markham GD, Seeholzer SH, Stoerker J, Genuardi M, Yeung AT, Matsumoto Y and Bellacosa A. (2000). J. Biol. Chem., 275, 32422-32429.
78. Radany EH, Dornfeld KJ, Sanderson RJ, Savage MK, Majumdar A, Seidman MM and Mosbaugh DW. (2000). Mutat. Res., 461, 41-58.
79. Riccio A, Aaltonen LA, Godwin AK, Loukola A, Percesepe A, Salovaara R, Masciullo V, Genuardi M, Paravatou-Petsotas M, Bassi DE, Ruggeri BA, Klein-Szanto AJP, Testa JR, Neri G and Bellacosa A. (1999). Nature Genetics, 23, 266-268.
80. Robu ME, Inman RB and Cox MM. (2001). Proc. Natl. Acad. Sci. USA, 98, 8211-8218.
81. Rossi R, Villa A, Negri C, Scovassi I, Ciarrocchi G, Biamonti G and Montecucco A. (1999). EMBO J., 18, 5745-5754.
82. Rusmintratip V and Sowers LC. (2000). Proc. Natl. Acad. Sci. USA, 97, 14183-14187.
83. Saparbaev M and Laval J. (1998). Proc. Natl. Acad. Sci. USA, 95, 8508-8513.
84. Sartori AA, Fitz-Gibbon S, Hanjing Y, Miller JH and Jiricny J. (2002). EMBO J., 21, 3182-3191.
85. Sartori AA, Schar P, Fitz-Gibbon S, Miller JH and Jiricny J. (2001). J. Biol. Chem., 276, 29979-29986.
86. Savva R, McAuley Hecht K, Brown T and Pearl L. (1995). Nature, 373, 487-493.
87. Sekiguchi M, Hayakawa M, Makino F, Tanaka K and Okada Y. (1976). Biochem. Biophys. Res. Commun., 73, 293-299.
88. Shapiro R. (1980). Chromosome damage and repair. Seeberg E, Kleppe K (ed). New York: Plenum Press, pp. 3-18.
89. Sheehy AM, Gaddis NC, Choi JD and Malim MH. (2002). Nature, 418, 646-650.
90. Shroyer MJ, Bennett SE, Putnam CD, Tainer JA and Mosbaugh DW. (1999). Biochemistry, 38, 4834-4845.
91. Slupphaug G, Eftedal I, Kavli B, Bharati S, Helle NM, Haug T, Levine DW and Krokan HE. (1995). Biochemistry, 34, 128-138.
92. Slupphaug G, Mol CD, Kavli B, Arvai AS, Krokan HE and Tainer JA. (1996). Nature, 384, 87-92.
93. Spek EJ, Wright TL, Stitt MS, Taghizadeh NR, Tannenbaum SR, Marinus MG and Engelward BP. (2001). J. Bact., 183, 131-138.
94. Stivers JT, Pankiewicz KW and Watanabe KA. (1999). Biochemistry, 38, 952-963.
95. Thayer MM, Ahern H, Xing D, Cunningham RP and Tainer JA. (1995). EMBO J., 14, 4108-4120.
96. Tu YQ, Dammann R and Pfeifer GP. (1998). J. Mol. Biol., 284, 297-311.
97. Tye BK, Nyman PO, Lehman IR, Hochhauser S and Weiss B. (1977). Proc. Natl. Acad. Sci. USA, 74, 154-157.
98. Um S, Harbers M, Benecke A, Pieratt B, Losson R and Chambon P. (1998). J. Biol. Chem., 273, 20728-20736.
99. Vidal AE, Hickson ID, Boiteux S and Radicella JP. (2001). Nucleic Acids Res., 29, 1285-1292.
100. Vilpo JA and Vilpo LM. (1995). Mutat. Res., 316, 123-131.
101. Waters TR, Gallinari P, Jiricny J and Swann PF. (1999). J. Biol. Chem., 274, 67-74.
102. Waters TR and Swann PF. (2000). Mutat. Res., 462, 137-147.
103. Werner RM, Jiang YL, Gordley RG, Jagadeesh GJ, Ladner JE, Xiao G, Tordova M, Gilliland GL and Stivers JT. (2000). Biochemistry, 39, 12585-12594.
104. Werner RM and Stivers JT. (2000). Biochemistry, 39, 14054-14064.
105. Willetts KE, Rey F, Agostini I, Navarro JM, Baudat Y, Vigne R and Sire J. (1999). J. Virol., 73, 1682-1688.
106. Wist E, Unhjem O and Krokan HE. (1978). Biochim. Biophys. Acta. 250, 253-270.
107. Wittwer CU, Bauw G and Krokan HE. (1989). Biochemistry, 28, 780-784.
108. Wong I, Lundquist AJ, Bernards AS and Mosbaugh DW. (2002). J. Biol. Chem., 277, 19424-19432.
109. Xiao G, Tordova M, Jagadeesh J, Drohat AC, Stivers JT and Gilliland GL. (1999). Proteins, 35, 13-24.
110. Zhu B, Zheng Y, Angliker H, Schwarz S, Thiry S, Siegmann M and Jost JP. (2000a). Nucleic Acids Res., 28, 4157-4165.
111. Zhu B, Zheng Y, Hess D, Angliker H, Schwarz S, Siegmann M, Thiry S and Jost JP. (2000b). Proc. Natl. Acad. Sci. USA, 97, 5135-5139.