-
1
-
-
33846088785
-
The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint
-
Ahnesorg P, Jackson SP. (2007). The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint. DNA Repair (Amst) 6: 190-201.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 190-201
-
-
Ahnesorg, P.1
Jackson, S.P.2
-
2
-
-
31044432090
-
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
-
Ahnesorg P, Smith P, Jackson SP. (2006). XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell 124: 301-313.
-
(2006)
Cell
, vol.124
, pp. 301-313
-
-
Ahnesorg, P.1
Smith, P.2
Jackson, S.P.3
-
3
-
-
0033302071
-
An evolutionary classification of the metallo-beta-lactamase fold proteins
-
Aravind L. (1999). An evolutionary classification of the metallo-beta-lactamase fold proteins. In Silico Biol 1: 69-91.
-
(1999)
In Silico Biol
, vol.1
, pp. 69-91
-
-
Aravind, L.1
-
4
-
-
11244280890
-
Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
-
Audebert M, Salles B, Calsou P. (2004). Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. J Biol Chem 279: 55117-55126.
-
(2004)
J Biol Chem
, vol.279
, pp. 55117-55126
-
-
Audebert, M.1
Salles, B.2
Calsou, P.3
-
5
-
-
2442706035
-
H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity
-
Bassing CH, Alt FW. (2004). H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity. Cell Cycle 3: 149-153.
-
(2004)
Cell Cycle
, vol.3
, pp. 149-153
-
-
Bassing, C.H.1
Alt, F.W.2
-
6
-
-
24344461251
-
A patient with mutations in DNA Ligase IV: Clinical features and overlap with Nijmegen breakage syndrome
-
Ben-Omran TI, Cerosaletti K, Concannon P, Weitzman S, Nezarati MM. (2005). A patient with mutations in DNA Ligase IV: clinical features and overlap with Nijmegen breakage syndrome. Am J Med Genet A 137: 283-287.
-
(2005)
Am J Med Genet A
, vol.137
, pp. 283-287
-
-
Ben-Omran, T.I.1
Cerosaletti, K.2
Concannon, P.3
Weitzman, S.4
Nezarati, M.M.5
-
7
-
-
0026071588
-
Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
-
Biedermann KA, Sum JR, Giaccia AJ, Tosto LM, Brown JM. (1991). Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc Natl Acad Sci USA 88: 1394-1397.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1394-1397
-
-
Biedermann, K.A.1
Sum, J.R.2
Giaccia, A.J.3
Tosto, L.M.4
Brown, J.M.5
-
8
-
-
0020663062
-
A severe combined immunodeficiency mutation in the mouse
-
Bosma GC, Custer RP, Bosma MJ. (1983). A severe combined immunodeficiency mutation in the mouse. Nature 301: 527-530.
-
(1983)
Nature
, vol.301
, pp. 527-530
-
-
Bosma, G.C.1
Custer, R.P.2
Bosma, M.J.3
-
9
-
-
0037011116
-
DNA-dependent protein kinase activity is not required for immunoglobulin class switching
-
Bosma GC, Kim J, Urich T, Fath DM, Cotticelli MG, Ruetsch NR et al. (2002). DNA-dependent protein kinase activity is not required for immunoglobulin class switching. J Exp Med 196: 1483-1495.
-
(2002)
J Exp Med
, vol.196
, pp. 1483-1495
-
-
Bosma, G.C.1
Kim, J.2
Urich, T.3
Fath, D.M.4
Cotticelli, M.G.5
Ruetsch, N.R.6
-
10
-
-
0029791694
-
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
-
Boulton SJ, Jackson SP. (1996). Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J 15: 5093-5103.
-
(1996)
EMBO J
, vol.15
, pp. 5093-5103
-
-
Boulton, S.J.1
Jackson, S.P.2
-
11
-
-
31044440630
-
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
-
Buck D, Malivert L, de Chasseval R, Barraud A, Fondaneche MC, Sanal O et al. (2006a). Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. Cell 124: 287-299.
-
(2006)
Cell
, vol.124
, pp. 287-299
-
-
Buck, D.1
Malivert, L.2
de Chasseval, R.3
Barraud, A.4
Fondaneche, M.C.5
Sanal, O.6
-
12
-
-
30944455282
-
Severe combined immunodeficiency and microcephaly in siblings with hypomorphic mutations in DNA ligase IV
-
Buck D, Moshous D, de Chasseval R, Ma Y, le Deist F, Cavazzana-Calvo M et al. (2006b). Severe combined immunodeficiency and microcephaly in siblings with hypomorphic mutations in DNA ligase IV. Eur J Immunol 36: 224-235.
-
(2006)
Eur J Immunol
, vol.36
, pp. 224-235
-
-
Buck, D.1
Moshous, D.2
de Chasseval, R.3
Ma, Y.4
le Deist, F.5
Cavazzana-Calvo, M.6
-
13
-
-
33744938713
-
Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1
-
Callebaut I, Malivert L, Fischer A, Mornon JP, Revy P, de Villartay JP. (2006). Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1. J Biol Chem 281: 13857-13860.
-
(2006)
J Biol Chem
, vol.281
, pp. 13857-13860
-
-
Callebaut, I.1
Malivert, L.2
Fischer, A.3
Mornon, J.P.4
Revy, P.5
de Villartay, J.P.6
-
14
-
-
0037102538
-
Metallo-β-lactamase fold within nucleic acids processing enzymes: The β-CASP family
-
Callebaut I, Moshous D, Mornon JP, De Villartay JP. (2002). Metallo-β-lactamase fold within nucleic acids processing enzymes: the β-CASP family. Nucl Acid Res 30: 3592-3601.
-
(2002)
Nucl Acid Res
, vol.30
, pp. 3592-3601
-
-
Callebaut, I.1
Moshous, D.2
Mornon, J.P.3
De Villartay, J.P.4
-
15
-
-
0032522564
-
Ku80 is required for immunoglobulin isotype switching
-
Casellas R, Nussenzweig A, Wuerffel R, Pelanda R, Reichlin A, Suh H et al. (1998). Ku80 is required for immunoglobulin isotype switching. EMBO J 17: 2404-2411.
-
(1998)
EMBO J
, vol.17
, pp. 2404-2411
-
-
Casellas, R.1
Nussenzweig, A.2
Wuerffel, R.3
Pelanda, R.4
Reichlin, A.5
Suh, H.6
-
16
-
-
0042931069
-
The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region
-
Catalan N, Selz F, Imai K, Revy P, Fischer A, Durandy A. (2003). The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region. J Immunol 171: 2504-2509.
-
(2003)
J Immunol
, vol.171
, pp. 2504-2509
-
-
Catalan, N.1
Selz, F.2
Imai, K.3
Revy, P.4
Fischer, A.5
Durandy, A.6
-
17
-
-
0027404942
-
Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency
-
Cavazzana-Calvo M, Le Deist F, de Saint Basile G, Papadopoulo D, de Villartay JP, Fischer A. (1993). Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency. J Clin Invest 91: 1214-1218.
-
(1993)
J Clin Invest
, vol.91
, pp. 1214-1218
-
-
Cavazzana-Calvo, M.1
Le Deist, F.2
de Saint Basile, G.3
Papadopoulo, D.4
de Villartay, J.P.5
Fischer, A.6
-
18
-
-
34247877686
-
Xlf1 is required for DNA repair by nonhomologous end joining in Schizosaccharomyces pombe
-
Cavero S, Chahwan C, Russell P. (2007). Xlf1 is required for DNA repair by nonhomologous end joining in Schizosaccharomyces pombe. Genetics 175: 963-967.
-
(2007)
Genetics
, vol.175
, pp. 963-967
-
-
Cavero, S.1
Chahwan, C.2
Russell, P.3
-
19
-
-
3142765336
-
Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair
-
Chaudhuri J, Alt FW. (2004). Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat Rev Immunol 4: 541-552.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 541-552
-
-
Chaudhuri, J.1
Alt, F.W.2
-
20
-
-
20144370280
-
Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage
-
Chen L, Morio T, Minegishi Y, Nakada S, Nagasawa M, Komatsu K et al. (2005). Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage. Cancer Sci 96: 134-141.
-
(2005)
Cancer Sci
, vol.96
, pp. 134-141
-
-
Chen, L.1
Morio, T.2
Minegishi, Y.3
Nakada, S.4
Nagasawa, M.5
Komatsu, K.6
-
21
-
-
0345735841
-
Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions
-
Cook AJ, Oganesian L, Harumal P, Basten A, Brink R, Jolly CJ. (2003). Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions. J Immunol 171: 6556-6564.
-
(2003)
J Immunol
, vol.171
, pp. 6556-6564
-
-
Cook, A.J.1
Oganesian, L.2
Harumal, P.3
Basten, A.4
Brink, R.5
Jolly, C.J.6
-
22
-
-
34848843525
-
Rag mutations reveal robust alternative end joining
-
Corneo B, Wendland RL, Deriano L, Cui X, Klein I, SY W et al. (2007). Rag mutations reveal robust alternative end joining. Nature 449: 483-486.
-
(2007)
Nature
, vol.449
, pp. 483-486
-
-
Corneo, B.1
Wendland, R.L.2
Deriano, L.3
Cui, X.4
Klein, I.5
SY, W.6
-
23
-
-
0345505218
-
Nonhomologous end joining and V(D)J recombination require an additional factor
-
Dai Y, Kysela B, Hanakahi LA, Manolis K, Riballo E, Stumm M et al. (2003). Nonhomologous end joining and V(D)J recombination require an additional factor. Proc Natl Acad Sci USA 100: 2462-2467.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2462-2467
-
-
Dai, Y.1
Kysela, B.2
Hanakahi, L.A.3
Manolis, K.4
Riballo, E.5
Stumm, M.6
-
24
-
-
33846021317
-
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle
-
Darroudi F, Wiegant W, Meijers M, Friedl AA, van der Burg M, Fomina J et al. (2007). Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle. Mutat Res 615: 111-124.
-
(2007)
Mutat Res
, vol.615
, pp. 111-124
-
-
Darroudi, F.1
Wiegant, W.2
Meijers, M.3
Friedl, A.A.4
van der Burg, M.5
Fomina, J.6
-
25
-
-
33947204449
-
Chromosome breakage after G2 checkpoint release
-
Deckbar D, Birraux J, Krempler A, Tchouandong L, Beucher A, Walker S et al. (2007). Chromosome breakage after G2 checkpoint release. J Cell Biol 176: 749-755.
-
(2007)
J Cell Biol
, vol.176
, pp. 749-755
-
-
Deckbar, D.1
Birraux, J.2
Krempler, A.3
Tchouandong, L.4
Beucher, A.5
Walker, S.6
-
26
-
-
34547132093
-
Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination
-
Decottignies A. (2007). Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination. Genetics 176: 1403-1415.
-
(2007)
Genetics
, vol.176
, pp. 1403-1415
-
-
Decottignies, A.1
-
27
-
-
34548567192
-
Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4
-
Deshpande RA, Wilson TE. (2007). Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4. DNA Repair 6: 1507-1516.
-
(2007)
DNA Repair
, vol.6
, pp. 1507-1516
-
-
Deshpande, R.A.1
Wilson, T.E.2
-
28
-
-
33748872519
-
Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends
-
Drouet J, Frit P, Delteil C, de Villartay JP, Salles B, Calsou P. (2006). Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends. J Biol Chem 281: 27784-27793.
-
(2006)
J Biol Chem
, vol.281
, pp. 27784-27793
-
-
Drouet, J.1
Frit, P.2
Delteil, C.3
de Villartay, J.P.4
Salles, B.5
Calsou, P.6
-
29
-
-
13444301307
-
Mechanism and control of V(D)J recombination versus class switch recombination: Similarities and differences
-
Dudley DD, Chaudhuri J, Bassing CH, Alt FW. (2005). Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. Adv Immunol 86: 43-112.
-
(2005)
Adv Immunol
, vol.86
, pp. 43-112
-
-
Dudley, D.D.1
Chaudhuri, J.2
Bassing, C.H.3
Alt, F.W.4
-
30
-
-
19344374008
-
Omenn syndrome due to ARTEMIS mutations
-
Ege M, Ma Y, Manfras B, Kalwak K, Lu H, Lieber MR et al. (2005). Omenn syndrome due to ARTEMIS mutations. Blood 105: 4179-4186.
-
(2005)
Blood
, vol.105
, pp. 4179-4186
-
-
Ege, M.1
Ma, Y.2
Manfras, B.3
Kalwak, K.4
Lu, H.5
Lieber, M.R.6
-
31
-
-
33645785057
-
A severe form of human combined immunodeficiency due to mutations in DNA ligase IV
-
Enders A, Fisch P, Schwarz K, Duffner U, Pannicke U, Nikolopoulos E et al. (2006). A severe form of human combined immunodeficiency due to mutations in DNA ligase IV. J Immunol 176: 5060-5068.
-
(2006)
J Immunol
, vol.176
, pp. 5060-5068
-
-
Enders, A.1
Fisch, P.2
Schwarz, K.3
Duffner, U.4
Pannicke, U.5
Nikolopoulos, E.6
-
32
-
-
33645834965
-
Radiation-induced delayed cell death in a hypomorphic Artemis cell line
-
Evans PM, Woodbine L, Riballo E, Gennery AR, Hubank M, Jeggo PA. (2006). Radiation-induced delayed cell death in a hypomorphic Artemis cell line. Hum Mol Genet 15: 1303-1311.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1303-1311
-
-
Evans, P.M.1
Woodbine, L.2
Riballo, E.3
Gennery, A.R.4
Hubank, M.5
Jeggo, P.A.6
-
33
-
-
0345865076
-
Human primary immunodeficiency diseases: A perspective
-
Fischer A. (2004). Human primary immunodeficiency diseases: a perspective. Nat Immunol 5: 23-30.
-
(2004)
Nat Immunol
, vol.5
, pp. 23-30
-
-
Fischer, A.1
-
34
-
-
33748144349
-
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
-
Franco S, Alt FW, Manis JP. (2006). Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations. DNA Repair (Amst) 5: 1030-1041.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 1030-1041
-
-
Franco, S.1
Alt, F.W.2
Manis, J.P.3
-
35
-
-
0032511976
-
Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV
-
Frank KM, Sekiguchi JM, Seidl KJ, Swat W, Rathbun GA, Cheng HL et al. (1998). Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV. Nature 396: 173-177.
-
(1998)
Nature
, vol.396
, pp. 173-177
-
-
Frank, K.M.1
Sekiguchi, J.M.2
Seidl, K.J.3
Swat, W.4
Rathbun, G.A.5
Cheng, H.L.6
-
36
-
-
0035889233
-
NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway
-
Frank-Vaillant M, Marcand S. (2001). NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev 15: 3005-3012.
-
(2001)
Genes Dev
, vol.15
, pp. 3005-3012
-
-
Frank-Vaillant, M.1
Marcand, S.2
-
37
-
-
0025011134
-
The scid mutation in mice causes a general defect in DNA repair
-
Fulop GM, Phillips RA. (1990). The scid mutation in mice causes a general defect in DNA repair. Nature 347: 479-482.
-
(1990)
Nature
, vol.347
, pp. 479-482
-
-
Fulop, G.M.1
Phillips, R.A.2
-
38
-
-
0032417640
-
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
-
Gao Y, Sun Y, Frank KM, Dikkes P, Fujiwara Y, Seidl KJ et al. (1998). A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 95: 891-902.
-
(1998)
Cell
, vol.95
, pp. 891-902
-
-
Gao, Y.1
Sun, Y.2
Frank, K.M.3
Dikkes, P.4
Fujiwara, Y.5
Seidl, K.J.6
-
39
-
-
34147216135
-
Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B
-
Geng L, Zhang X, Zheng S, Legerski RJ. (2007). Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B. Mol Cell Biol 27: 2625-2635.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2625-2635
-
-
Geng, L.1
Zhang, X.2
Zheng, S.3
Legerski, R.J.4
-
40
-
-
23444456160
-
Omenn's syndrome occurring in patients without mutations in recombination activating genes
-
Gennery AR, Hodges E, Williams AP, Harris S, Villa A, Angus B et al. (2005). Omenn's syndrome occurring in patients without mutations in recombination activating genes. Clin Immunol 116: 246-256.
-
(2005)
Clin Immunol
, vol.116
, pp. 246-256
-
-
Gennery, A.R.1
Hodges, E.2
Williams, A.P.3
Harris, S.4
Villa, A.5
Angus, B.6
-
41
-
-
33748089029
-
DNA-PK autophosphorylation facilitates Artemis endonuclease activity
-
Goodarzi AA, Yu Y, Riballo E, Douglas P, Walker SA, Ye R et al. (2006). DNA-PK autophosphorylation facilitates Artemis endonuclease activity. EMBO J 25: 3880-3889.
-
(2006)
EMBO J
, vol.25
, pp. 3880-3889
-
-
Goodarzi, A.A.1
Yu, Y.2
Riballo, E.3
Douglas, P.4
Walker, S.A.5
Ye, R.6
-
42
-
-
0030743386
-
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
-
Grawunder U, Wilm M, Wu X, Kulesza P, Wilson TE, Mann M et al. (1997). Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 388: 492-495.
-
(1997)
Nature
, vol.388
, pp. 492-495
-
-
Grawunder, U.1
Wilm, M.2
Wu, X.3
Kulesza, P.4
Wilson, T.E.5
Mann, M.6
-
43
-
-
0032537803
-
DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains
-
Grawunder U, Zimmer D, Leiber MR. (1998). DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains. Curr Biol 8: 873-876.
-
(1998)
Curr Biol
, vol.8
, pp. 873-876
-
-
Grawunder, U.1
Zimmer, D.2
Leiber, M.R.3
-
44
-
-
34848841930
-
Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: Influence of terminal DNA sequence
-
Gu J, Lu H, Tsai AG, Schwarz K, Lieber MR. (2007). Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence. Nucleic Acids Res 35: 5755-5762.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5755-5762
-
-
Gu, J.1
Lu, H.2
Tsai, A.G.3
Schwarz, K.4
Lieber, M.R.5
-
45
-
-
0025778519
-
A link between double-strand break related repair and V(D)J recombination : The scid mutation
-
Hendrickson EA, Qin XQ, Bump EA, Schatz DG, Oettinger M, Weaver DT. (1991). A link between double-strand break related repair and V(D)J recombination : the scid mutation. Proc Natl Acad Sci USA 88: 4061-4065.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4061-4065
-
-
Hendrickson, E.A.1
Qin, X.Q.2
Bump, E.A.3
Schatz, D.G.4
Oettinger, M.5
Weaver, D.T.6
-
46
-
-
33846002032
-
Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos
-
Hentges P, Ahnesorg P, Pitcher RS, Bruce CK, Kysela B, Green AJ et al. (2006). Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos. J Biol Chem 281: 37517-37526.
-
(2006)
J Biol Chem
, vol.281
, pp. 37517-37526
-
-
Hentges, P.1
Ahnesorg, P.2
Pitcher, R.S.3
Bruce, C.K.4
Kysela, B.5
Green, A.J.6
-
47
-
-
0142092610
-
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
-
Imai K, Slupphaug G, Lee WI, Revy P, Nonoyama S, Catalan N et al. (2003). Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Nat Immunol 4: 1023-1028.
-
(2003)
Nat Immunol
, vol.4
, pp. 1023-1028
-
-
Imai, K.1
Slupphaug, G.2
Lee, W.I.3
Revy, P.4
Nonoyama, S.5
Catalan, N.6
-
48
-
-
35148863458
-
A role of DNA-PKcs and Artemis in opening viral DNA hairpin termini in various tissues in mice
-
Inagaki K, Ma C, Storm TA, Kay MA, Nakai H. (2007). A role of DNA-PKcs and Artemis in opening viral DNA hairpin termini in various tissues in mice. J Virol 81: 11304-11321.
-
(2007)
J Virol
, vol.81
, pp. 11304-11321
-
-
Inagaki, K.1
Ma, C.2
Storm, T.A.3
Kay, M.A.4
Nakai, H.5
-
49
-
-
33845286132
-
Crystal structure of TTHA0252 from Thermus thermophilus HB8, a RNA degradation protein of the metallo-beta-lactamase superfamily
-
Ishikawa H, Nakagawa N, Kuramitsu S, Masui R. (2006). Crystal structure of TTHA0252 from Thermus thermophilus HB8, a RNA degradation protein of the metallo-beta-lactamase superfamily. J Biochem (Tokyo) 140: 535-542.
-
(2006)
J Biochem (Tokyo)
, vol.140
, pp. 535-542
-
-
Ishikawa, H.1
Nakagawa, N.2
Kuramitsu, S.3
Masui, R.4
-
50
-
-
34547115451
-
Antigen receptor diversification and chromosome translocations
-
Jankovic M, Nussenzweig A, Nussenzweig MC. (2007). Antigen receptor diversification and chromosome translocations. Nat Immunol 8: 801-808.
-
(2007)
Nat Immunol
, vol.8
, pp. 801-808
-
-
Jankovic, M.1
Nussenzweig, A.2
Nussenzweig, M.C.3
-
51
-
-
0034669204
-
Crystal structure of the Xrcc4 DNA repair protein and implications for end joining
-
Junop MS, Modesti M, Guarne A, Ghirlando R, Gellert M, Yang W. (2000). Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. EMBO J 19: 5962-5970.
-
(2000)
EMBO J
, vol.19
, pp. 5962-5970
-
-
Junop, M.S.1
Modesti, M.2
Guarne, A.3
Ghirlando, R.4
Gellert, M.5
Yang, W.6
-
52
-
-
0035899933
-
Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast
-
Kegel A, Sjostrand JO, Astrom SU. (2001). Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast. Curr Biol 11: 1611-1617.
-
(2001)
Curr Biol
, vol.11
, pp. 1611-1617
-
-
Kegel, A.1
Sjostrand, J.O.2
Astrom, S.U.3
-
53
-
-
33847276659
-
The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination
-
Kiefer K, Oshinsky J, Kim J, Nakajima PB, Bosma GC, Bosma MJ. (2007). The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination. Proc Natl Acad Sci USA 104: 2843-2848.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2843-2848
-
-
Kiefer, K.1
Oshinsky, J.2
Kim, J.3
Nakajima, P.B.4
Bosma, G.C.5
Bosma, M.J.6
-
54
-
-
13444281917
-
Nibrin functions in Ig class-switch recombination
-
Kracker S, Bergmann Y, Demuth I, Frappart PO, Hildebrand G, Christine R et al. (2005). Nibrin functions in Ig class-switch recombination. Proc Natl Acad Sci USA 102: 1584-1589.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1584-1589
-
-
Kracker, S.1
Bergmann, Y.2
Demuth, I.3
Frappart, P.O.4
Hildebrand, G.5
Christine, R.6
-
55
-
-
34548223252
-
An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells
-
Krempler A, Deckbar D, Jeggo PA, Lobrich M. (2007). An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells. Cell Cycle 6: 1682-1686.
-
(2007)
Cell Cycle
, vol.6
, pp. 1682-1686
-
-
Krempler, A.1
Deckbar, D.2
Jeggo, P.A.3
Lobrich, M.4
-
56
-
-
1942421722
-
RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination
-
Lee GS, Neiditch MB, Salus SS, Roth DB. (2004). RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination. Cell 117: 171-184.
-
(2004)
Cell
, vol.117
, pp. 171-184
-
-
Lee, G.S.1
Neiditch, M.B.2
Salus, S.S.3
Roth, D.B.4
-
57
-
-
33745651993
-
The Apollo 5′ exonuclease functions together with TRF2 to protect telomeres from DNA repair
-
Lenain C, Bauwens S, Amiard S, Brunori M, Giraud-Panis MJ, Gilson E. (2006). The Apollo 5′ exonuclease functions together with TRF2 to protect telomeres from DNA repair. Curr Biol 16: 1303-1310.
-
(2006)
Curr Biol
, vol.16
, pp. 1303-1310
-
-
Lenain, C.1
Bauwens, S.2
Amiard, S.3
Brunori, M.4
Giraud-Panis, M.J.5
Gilson, E.6
-
58
-
-
0031893610
-
The gene for severe combined immunodeficiency disease in Athabascan-speaking native Americans is located on chromosome 10p
-
Li L, Drayna D, Hu D, Hayward A, Gahagan S, Pabst H et al. (1998). The gene for severe combined immunodeficiency disease in Athabascan-speaking native Americans is located on chromosome 10p. Am J Hum Genet 62: 136-144.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 136-144
-
-
Li, L.1
Drayna, D.2
Hu, D.3
Hayward, A.4
Gahagan, S.5
Pabst, H.6
-
59
-
-
13544259957
-
Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation
-
Li L, Salido E, Zhou Y, Bhattacharyya S, Yannone SM, Dunn E et al. (2005). Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation. J Immunol 174: 2420-2428.
-
(2005)
J Immunol
, vol.174
, pp. 2420-2428
-
-
Li, L.1
Salido, E.2
Zhou, Y.3
Bhattacharyya, S.4
Yannone, S.M.5
Dunn, E.6
-
60
-
-
0023801238
-
The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
-
Lieber MR, Hesse JE, Lewis S, Bosma GC, Rosenberg N, Mizuuchi K et al. (1988). The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination. Cell 55: 7-16.
-
(1988)
Cell
, vol.55
, pp. 7-16
-
-
Lieber, M.R.1
Hesse, J.E.2
Lewis, S.3
Bosma, G.C.4
Rosenberg, N.5
Mizuuchi, K.6
-
61
-
-
34249685474
-
Length-dependent binding of human XLF to DNA and stimulation of XRCC4·DNA ligase IV activity
-
Lu H, Pannicke U, Schwarz K, Lieber MR. (2007). Length-dependent binding of human XLF to DNA and stimulation of XRCC4·DNA ligase IV activity. J Biol Chem 282: 11155-11162.
-
(2007)
J Biol Chem
, vol.282
, pp. 11155-11162
-
-
Lu, H.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
62
-
-
8644242383
-
Immunoglobulin class switch recombination is impaired in Atm-deficient mice
-
Lumsden JM, McCarty T, Petiniot LK, Shen R, Barlow C, Wynn TA et al. (2004). Immunoglobulin class switch recombination is impaired in Atm-deficient mice. J Exp Med 200: 1111-1121.
-
(2004)
J Exp Med
, vol.200
, pp. 1111-1121
-
-
Lumsden, J.M.1
McCarty, T.2
Petiniot, L.K.3
Shen, R.4
Barlow, C.5
Wynn, T.A.6
-
63
-
-
26644444577
-
The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis
-
Ma Y, Pannicke U, Lu H, Niewolik D, Schwarz K, Lieber MR. (2005). The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis. J Biol Chem 280: 33839-33846.
-
(2005)
J Biol Chem
, vol.280
, pp. 33839-33846
-
-
Ma, Y.1
Pannicke, U.2
Lu, H.3
Niewolik, D.4
Schwarz, K.5
Lieber, M.R.6
-
64
-
-
0037155703
-
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
-
Ma Y, Pannicke U, Schwarz K, Lieber MR. (2002). Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108: 781-794.
-
(2002)
Cell
, vol.108
, pp. 781-794
-
-
Ma, Y.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
65
-
-
33845902048
-
Polyadenylation factor CPSF-73 is the pre-mRNA 3′-end-processing endonuclease
-
Mandel CR, Kaneko S, Zhang H, Gebauer D, Vethantham V, Manley JL et al. (2006). Polyadenylation factor CPSF-73 is the pre-mRNA 3′-end-processing endonuclease. Nature 444: 953-956.
-
(2006)
Nature
, vol.444
, pp. 953-956
-
-
Mandel, C.R.1
Kaneko, S.2
Zhang, H.3
Gebauer, D.4
Vethantham, V.5
Manley, J.L.6
-
66
-
-
0036224604
-
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
-
Manis JP, Dudley D, Kaylor L, Alt FW. (2002a). IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells. Immunity 16: 607-617.
-
(2002)
Immunity
, vol.16
, pp. 607-617
-
-
Manis, J.P.1
Dudley, D.2
Kaylor, L.3
Alt, F.W.4
-
67
-
-
0032526290
-
Ku70 is required for late B cell development and immunoglobulin heavy chain class switching
-
Manis JP, Gu Y, Lansford R, Sonoda E, Ferrini R, Davidson L et al. (1998). Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. J Exp Med 187: 2081-2089.
-
(1998)
J Exp Med
, vol.187
, pp. 2081-2089
-
-
Manis, J.P.1
Gu, Y.2
Lansford, R.3
Sonoda, E.4
Ferrini, R.5
Davidson, L.6
-
68
-
-
2442707746
-
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
-
Manis JP, Morales JC, Xia Z, Kutok JL, Alt FW, Carpenter PB. (2004). 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat Immunol 5: 481-487.
-
(2004)
Nat Immunol
, vol.5
, pp. 481-487
-
-
Manis, J.P.1
Morales, J.C.2
Xia, Z.3
Kutok, J.L.4
Alt, F.W.5
Carpenter, P.B.6
-
69
-
-
0036152242
-
Mechanism and control of classs-witch recombination
-
Manis JP, Tian M, Alt FW. (2002b). Mechanism and control of classs-witch recombination. Trends Immunol 23: 31-39.
-
(2002)
Trends Immunol
, vol.23
, pp. 31-39
-
-
Manis, J.P.1
Tian, M.2
Alt, F.W.3
-
70
-
-
0035917489
-
ARTEMIS, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F et al. (2001a). ARTEMIS, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105: 177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
Callebaut, I.2
de Chasseval, R.3
Corneo, B.4
Cavazzana-Calvo, M.5
Le Deist, F.6
-
71
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F et al. (2001b). Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105: 177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
Callebaut, I.2
de Chasseval, R.3
Corneo, B.4
Cavazzana-Calvo, M.5
Le Deist, F.6
-
72
-
-
0034162828
-
A new gene involved in DNA double-strand break repair and V(D)J recombination is located on human chromosome 10p
-
Moshous D, Li L, de Chasseval R, Philippe N, Jabado N, Cowan MJ et al. (2000). A new gene involved in DNA double-strand break repair and V(D)J recombination is located on human chromosome 10p. Hum Mol Genet 9: 583-588.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 583-588
-
-
Moshous, D.1
Li, L.2
de Chasseval, R.3
Philippe, N.4
Jabado, N.5
Cowan, M.J.6
-
73
-
-
0037312006
-
Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis
-
Moshous D, Pannetier C, Chasseval Rd R, Deist Fl F, Cavazzana-Calvo M, Romana S et al. (2003). Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis. J Clin Invest 111: 381-387.
-
(2003)
J Clin Invest
, vol.111
, pp. 381-387
-
-
Moshous, D.1
Pannetier, C.2
Chasseval, R.R.3
Deist, F.F.4
Cavazzana-Calvo, M.5
Romana, S.6
-
74
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. (2000). Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102: 553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
75
-
-
0029971123
-
Lack of detectable defect in DNA double-strand break repair and DNA-dependant protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts
-
Nicolas N, Finnie NJ, Cavazzana-Calvo M, Papadopoulo D, Le Deist F, Fischer A et al. (1996). Lack of detectable defect in DNA double-strand break repair and DNA-dependant protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts. Eur J Immunol 26: 1118-1122.
-
(1996)
Eur J Immunol
, vol.26
, pp. 1118-1122
-
-
Nicolas, N.1
Finnie, N.J.2
Cavazzana-Calvo, M.3
Papadopoulo, D.4
Le Deist, F.5
Fischer, A.6
-
76
-
-
0032541313
-
A human SCID condition with increased sensitivity to ionizing radiations and impaired V(D)J rearrangements defines a new DNA recombination/repair deficiency
-
Nicolas N, Moshous D, Papadopoulo D, Cavazzana-Calvo M, de Chasseval R, le Deist F et al. (1998). A human SCID condition with increased sensitivity to ionizing radiations and impaired V(D)J rearrangements defines a new DNA recombination/repair deficiency. J Exp Med 188: 627-634.
-
(1998)
J Exp Med
, vol.188
, pp. 627-634
-
-
Nicolas, N.1
Moshous, D.2
Papadopoulo, D.3
Cavazzana-Calvo, M.4
de Chasseval, R.5
le Deist, F.6
-
77
-
-
33750685856
-
DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5′ or 3′ overhangs
-
Niewolik D, Pannicke U, Lu H, Ma Y, Wang LC, Kulesza P et al. (2006). DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5′ or 3′ overhangs. J Biol Chem 281: 33900-33909.
-
(2006)
J Biol Chem
, vol.281
, pp. 33900-33909
-
-
Niewolik, D.1
Pannicke, U.2
Lu, H.3
Ma, Y.4
Wang, L.C.5
Kulesza, P.6
-
78
-
-
18244362081
-
DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency
-
O'Driscoll M, Cerosaletti KM, Girard PM, Dai Y, Stumm M, Kysela B et al. (2001). DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency. Mol Cell 8: 1175-1185.
-
(2001)
Mol Cell
, vol.8
, pp. 1175-1185
-
-
O'Driscoll, M.1
Cerosaletti, K.M.2
Girard, P.M.3
Dai, Y.4
Stumm, M.5
Kysela, B.6
-
79
-
-
0025301095
-
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
-
Oettinger MA, Schatz DG, Gorka C, Baltimore D. (1990). RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 248: 1517-1523.
-
(1990)
Science
, vol.248
, pp. 1517-1523
-
-
Oettinger, M.A.1
Schatz, D.G.2
Gorka, C.3
Baltimore, D.4
-
80
-
-
0035930651
-
A DNA microarray-based genetic screen for nonhomologous end-joining mutants in Saccharomyces cerevisiae
-
Ooi SL, Shoemaker DD, Boeke JD. (2001). A DNA microarray-based genetic screen for nonhomologous end-joining mutants in Saccharomyces cerevisiae. Science 294: 2552-2556.
-
(2001)
Science
, vol.294
, pp. 2552-2556
-
-
Ooi, S.L.1
Shoemaker, D.D.2
Boeke, J.D.3
-
81
-
-
13244268505
-
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
-
Pan-Hammarstrom Q, Jones AM, Lahdesmaki A, Zhou W, Gatti RA, Hammarstrom L et al. (2005). Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells. J Exp Med 201: 189-194.
-
(2005)
J Exp Med
, vol.201
, pp. 189-194
-
-
Pan-Hammarstrom, Q.1
Jones, A.M.2
Lahdesmaki, A.3
Zhou, W.4
Gatti, R.A.5
Hammarstrom, L.6
-
82
-
-
3142555854
-
Functional and biochemical dissection of the structure-specific nuclease ARTEMIS
-
Pannicke U, Ma Y, Hopfner KP, Niewolik D, Lieber MR, Schwarz K. (2004). Functional and biochemical dissection of the structure-specific nuclease ARTEMIS. EMBO J 23: 1987-1997.
-
(2004)
EMBO J
, vol.23
, pp. 1987-1997
-
-
Pannicke, U.1
Ma, Y.2
Hopfner, K.P.3
Niewolik, D.4
Lieber, M.R.5
Schwarz, K.6
-
83
-
-
0036234455
-
Somatic hypermutation of immunoglobulin genes: Merging mechanisms for genetic diversity
-
Papavasiliou FN, Schatz DG. (2002). Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity. Cell 109(Suppl): S35-S44.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Papavasiliou, F.N.1
Schatz, D.G.2
-
84
-
-
0027245559
-
V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
-
Pergola F, Zdzienicka MZ, Lieber MR. (1993). V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol Cell Biol 13: 3464-3471.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 3464-3471
-
-
Pergola, F.1
Zdzienicka, M.Z.2
Lieber, M.R.3
-
85
-
-
34249058024
-
A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair
-
Peron S, Pan-Hammarstrom Q, Imai K, Du L, Taubenheim N, Sanal O et al. (2007). A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair. J Exp Med 204: 1207-1216.
-
(2007)
J Exp Med
, vol.204
, pp. 1207-1216
-
-
Peron, S.1
Pan-Hammarstrom, Q.2
Imai, K.3
Du, L.4
Taubenheim, N.5
Sanal, O.6
-
86
-
-
0035818990
-
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching
-
Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC et al. (2001). AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching. Nature 414: 660-665.
-
(2001)
Nature
, vol.414
, pp. 660-665
-
-
Petersen, S.1
Casellas, R.2
Reina-San-Martin, B.3
Chen, H.T.4
Difilippantonio, M.J.5
Wilson, P.C.6
-
87
-
-
9244239168
-
Phosphorylation of Artemis following irradiation-induced DNA damage
-
Poinsignon C, de Chasseval R, Soubeyrand S, Moshous D, Fischer A, Hache RJ et al. (2004a). Phosphorylation of Artemis following irradiation-induced DNA damage. Eur J Immunol 34: 3146-3155.
-
(2004)
Eur J Immunol
, vol.34
, pp. 3146-3155
-
-
Poinsignon, C.1
de Chasseval, R.2
Soubeyrand, S.3
Moshous, D.4
Fischer, A.5
Hache, R.J.6
-
88
-
-
1342300521
-
The metallo-β-lactamase/β-CASP domain of Artemis constitutes the catalytic core required for V(D)J recombination
-
Poinsignon C, Moshous D, Callebaut I, de Chasseval R, Villey I, de Villartay JP. (2004b). The metallo-β-lactamase/β-CASP domain of Artemis constitutes the catalytic core required for V(D)J recombination. J Exp Med 199: 315-321.
-
(2004)
J Exp Med
, vol.199
, pp. 315-321
-
-
Poinsignon, C.1
Moshous, D.2
Callebaut, I.3
de Chasseval, R.4
Villey, I.5
de Villartay, J.P.6
-
89
-
-
33947541157
-
Processing of 3′-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease
-
Povirk LF, Zhou T, Zhou R, Cowan MJ, Yannone SM. (2007). Processing of 3′-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease. J Biol Chem 282: 3547-3558.
-
(2007)
J Biol Chem
, vol.282
, pp. 3547-3558
-
-
Povirk, L.F.1
Zhou, T.2
Zhou, R.3
Cowan, M.J.4
Yannone, S.M.5
-
90
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada C, Williams GT, Nilsen H, Barnes DE, Lindahl T, Neuberger MS. (2002). Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr Biol 12: 1748-1755.
-
(2002)
Curr Biol
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindahl, T.5
Neuberger, M.S.6
-
91
-
-
8644238314
-
ATM is required for efficient recombination between immunoglobulin switch regions
-
Reina-San-Martin B, Chen HT, Nussenzweig A, Nussenzweig MC. (2004). ATM is required for efficient recombination between immunoglobulin switch regions. J Exp Med 200: 1103-1110.
-
(2004)
J Exp Med
, vol.200
, pp. 1103-1110
-
-
Reina-San-Martin, B.1
Chen, H.T.2
Nussenzweig, A.3
Nussenzweig, M.C.4
-
92
-
-
0037866984
-
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
-
Reina-San-Martin B, Difilippantonio S, Hanitsch L, Masilamani RF, Nussenzweig A, Nussenzweig MC. (2003). H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. J Exp Med 197: 1767-1778.
-
(2003)
J Exp Med
, vol.197
, pp. 1767-1778
-
-
Reina-San-Martin, B.1
Difilippantonio, S.2
Hanitsch, L.3
Masilamani, R.F.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
93
-
-
13444309097
-
Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1
-
Reina-San-Martin B, Nussenzweig MC, Nussenzweig A, Difilippantonio S. (2005). Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1. Proc Natl Acad Sci USA 102: 1590-1595.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1590-1595
-
-
Reina-San-Martin, B.1
Nussenzweig, M.C.2
Nussenzweig, A.3
Difilippantonio, S.4
-
94
-
-
23644452672
-
The repair of DNA damages/modifications during the maturation of the immune system: Lessons from human primary immunodeficiency disorders and animal models
-
Revy P, Buck D, le Deist F, de Villartay JP. (2005). The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models. Adv Immunol 87: 237-295.
-
(2005)
Adv Immunol
, vol.87
, pp. 237-295
-
-
Revy, P.1
Buck, D.2
le Deist, F.3
de Villartay, J.P.4
-
95
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2)
-
Revy P, Muto T, Levy Y, Geissmann F, Plebani A, Sanal O et al. (2000). Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2). Cell 102: 565-575.
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
Geissmann, F.4
Plebani, A.5
Sanal, O.6
-
96
-
-
9744220428
-
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci
-
Riballo E, Kuhne M, Rief N, Doherty A, Smith GC, Recio MJ et al. (2004). A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell 16: 715-724.
-
(2004)
Mol Cell
, vol.16
, pp. 715-724
-
-
Riballo, E.1
Kuhne, M.2
Rief, N.3
Doherty, A.4
Smith, G.C.5
Recio, M.J.6
-
97
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. (1998). DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273: 5858-5868.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
98
-
-
14044253569
-
Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development
-
Rooney S, Alt FW, Sekiguchi J, Manis JP. (2005). Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development. Proc Natl Acad Sci USA 102: 2471-2475.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2471-2475
-
-
Rooney, S.1
Alt, F.W.2
Sekiguchi, J.3
Manis, J.P.4
-
99
-
-
0036932453
-
Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice
-
Rooney S, Sekiguchi J, Zhu C, Cheng HL, Manis J, Whitlow S et al. (2002). Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol Cell 10: 1379-1390.
-
(2002)
Mol Cell
, vol.10
, pp. 1379-1390
-
-
Rooney, S.1
Sekiguchi, J.2
Zhu, C.3
Cheng, H.L.4
Manis, J.5
Whitlow, S.6
-
100
-
-
0141720776
-
Restraining the V(D)J recombinase
-
Roth DB. (2003). Restraining the V(D)J recombinase. Nat Rev Immunol 3: 656-666.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 656-666
-
-
Roth, D.B.1
-
101
-
-
0026792892
-
V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
-
Roth DB, Menetski JP, Nakajima PB, Bosma MJ, Gellert M. (1992). V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes. Cell 70: 983-991.
-
(1992)
Cell
, vol.70
, pp. 983-991
-
-
Roth, D.B.1
Menetski, J.P.2
Nakajima, P.B.3
Bosma, M.J.4
Gellert, M.5
-
102
-
-
0022256461
-
Mechanisms of nonhomologous recombination in mammalian cells
-
Roth DB, Porter TN, Wilson JH. (1985). Mechanisms of nonhomologous recombination in mammalian cells. Mol Cell Biol 5: 2599-2607.
-
(1985)
Mol Cell Biol
, vol.5
, pp. 2599-2607
-
-
Roth, D.B.1
Porter, T.N.2
Wilson, J.H.3
-
103
-
-
1842865725
-
Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination
-
Rush JS, Fugmann SD, Schatz DG. (2004). Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination. Int Immunol 16: 549-557.
-
(2004)
Int Immunol
, vol.16
, pp. 549-557
-
-
Rush, J.S.1
Fugmann, S.D.2
Schatz, D.G.3
-
105
-
-
0030749258
-
A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks
-
Schar P, Herrmann G, Daly G, Lindahl T. (1997). A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev 11: 1912-1924.
-
(1997)
Genes Dev
, vol.11
, pp. 1912-1924
-
-
Schar, P.1
Herrmann, G.2
Daly, G.3
Lindahl, T.4
-
106
-
-
0024846088
-
The V(D)J recombination activating gene, RAG-1
-
Schatz DG, Oettinger MA, Baltimore D. (1989). The V(D)J recombination activating gene, RAG-1. Cell 59: 1035-1048.
-
(1989)
Cell
, vol.59
, pp. 1035-1048
-
-
Schatz, D.G.1
Oettinger, M.A.2
Baltimore, D.3
-
107
-
-
0035191378
-
Crystal structure of an Xrcc4-DNA ligase IV complex
-
Sibanda BL, Critchlow SE, Begun J, Pei XY, Jackson SP, Blundell TL et al. (2001). Crystal structure of an Xrcc4-DNA ligase IV complex. Nat Struct Biol 8: 1015-1019.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 1015-1019
-
-
Sibanda, B.L.1
Critchlow, S.E.2
Begun, J.3
Pei, X.Y.4
Jackson, S.P.5
Blundell, T.L.6
-
108
-
-
33747889217
-
Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
-
Sonoda E, Hochegger H, Saberi A, Taniguchi Y, Takeda S. (2006). Differential usage of non-homologous end-joining and homologous recombination in double strand break repair. DNA Repair (Amst) 5: 1021-1029.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 1021-1029
-
-
Sonoda, E.1
Hochegger, H.2
Saberi, A.3
Taniguchi, Y.4
Takeda, S.5
-
109
-
-
33646090620
-
Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin
-
Soubeyrand S, Pope L, De Chasseval R, Gosselin D, Dong F, de Villartay JP et al. (2006). Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin. J Mol Biol 358: 1200-1211.
-
(2006)
J Mol Biol
, vol.358
, pp. 1200-1211
-
-
Soubeyrand, S.1
Pope, L.2
De Chasseval, R.3
Gosselin, D.4
Dong, F.5
de Villartay, J.P.6
-
110
-
-
34447288912
-
Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination
-
Soulas-Sprauel P, Le Guyader G, Rivera-Munoz P, Abramowski V, Olivier-Martin C, Goujet-Zalc C et al. (2007). Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination. J Exp Med 204: 1717-1727.
-
(2007)
J Exp Med
, vol.204
, pp. 1717-1727
-
-
Soulas-Sprauel, P.1
Le Guyader, G.2
Rivera-Munoz, P.3
Abramowski, V.4
Olivier-Martin, C.5
Goujet-Zalc, C.6
-
111
-
-
0027156278
-
Impairment of V(D)Jrecombinati on in double-strand break repair mutants
-
Taccioli GE, Rathbun G, Oltz E, Stamato T, Jeggo PA, Alt FW. (1993). Impairment of V(D)Jrecombinati on in double-strand break repair mutants. Science 260: 207-210.
-
(1993)
Science
, vol.260
, pp. 207-210
-
-
Taccioli, G.E.1
Rathbun, G.2
Oltz, E.3
Stamato, T.4
Jeggo, P.A.5
Alt, F.W.6
-
112
-
-
0030849085
-
Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
-
Teo SH, Jackson SP. (1997). Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair. EMBO J 16: 4788-4795.
-
(1997)
EMBO J
, vol.16
, pp. 4788-4795
-
-
Teo, S.H.1
Jackson, S.P.2
-
113
-
-
0034628617
-
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks
-
Teo SH, Jackson SP. (2000). Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks. Curr Biol 10: 165-168.
-
(2000)
Curr Biol
, vol.10
, pp. 165-168
-
-
Teo, S.H.1
Jackson, S.P.2
-
114
-
-
0020534965
-
Somatic generation of antibody diversity
-
Tonegawa S. (1983). Somatic generation of antibody diversity. Nature 302: 575-581.
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
115
-
-
34249938518
-
Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends
-
Tsai CJ, Kim SA, Chu G. (2007). Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proc Natl Acad Sci USA 104: 7851-7856.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7851-7856
-
-
Tsai, C.J.1
Kim, S.A.2
Chu, G.3
-
116
-
-
0035818985
-
NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae
-
Valencia M, Bentele M, Vaze MB, Herrmann G, Kraus E, Lee SE et al. (2001). NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature 414: 666-669.
-
(2001)
Nature
, vol.414
, pp. 666-669
-
-
Valencia, M.1
Bentele, M.2
Vaze, M.B.3
Herrmann, G.4
Kraus, E.5
Lee, S.E.6
-
117
-
-
31044446450
-
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation
-
van der Burg M, van Veelen LR, Verkaik NS, Wiegant WW, Hartwig NG, Barendregt BH et al. (2006). A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation. J Clin Invest 116: 137-145.
-
(2006)
J Clin Invest
, vol.116
, pp. 137-145
-
-
van der Burg, M.1
van Veelen, L.R.2
Verkaik, N.S.3
Wiegant, W.W.4
Hartwig, N.G.5
Barendregt, B.H.6
-
118
-
-
33745652501
-
Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase
-
van Overbeek M, de Lange T. (2006). Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase. Curr Biol 16: 1295-1302.
-
(2006)
Curr Biol
, vol.16
, pp. 1295-1302
-
-
van Overbeek, M.1
de Lange, T.2
-
119
-
-
0035161258
-
V(D)J recombination defects in lymphocytes due to RAG mutations: Severe immunodeficiency with a spectrum of clinical presentations
-
Villa A, Sobacchi C, Notarangelo LD, Bozzi F, Abinun M, Abrahamsen TG et al. (2001). V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations. Blood 97: 81-88.
-
(2001)
Blood
, vol.97
, pp. 81-88
-
-
Villa, A.1
Sobacchi, C.2
Notarangelo, L.D.3
Bozzi, F.4
Abinun, M.5
Abrahamsen, T.G.6
-
120
-
-
20144363082
-
DNA ligase III as a candidate component of backup pathways of nonhomologous end joining
-
Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F et al. (2005a). DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res 65: 4020-4030.
-
(2005)
Cancer Res
, vol.65
, pp. 4020-4030
-
-
Wang, H.1
Rosidi, B.2
Perrault, R.3
Wang, M.4
Zhang, L.5
Windhofer, F.6
-
121
-
-
16244401671
-
Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression
-
Wang J, Pluth JM, Cooper PK, Cowan MJ, Chen DJ, Yannone SM. (2005b). Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression. DNA Repair (Amst) 4: 556-570.
-
(2005)
DNA Repair (Amst)
, vol.4
, pp. 556-570
-
-
Wang, J.1
Pluth, J.M.2
Cooper, P.K.3
Cowan, M.J.4
Chen, D.J.5
Yannone, S.M.6
-
122
-
-
33845657443
-
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathway s
-
Wang M, Wu W, Rosidi B, Zhang L, Wang H, Iliakis G. (2006). PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathway s. Nucleic Acids Res 34: 6170-6182.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 6170-6182
-
-
Wang, M.1
Wu, W.2
Rosidi, B.3
Zhang, L.4
Wang, H.5
Iliakis, G.6
-
123
-
-
2542463148
-
53BP1 is required for class switch recombination
-
Ward IM, Reina-San-Martin B, Olaru A, Minn K, Tamada K, Lau JS et al. (2004). 53BP1 is required for class switch recombination. J Cell Biol 165: 459-464.
-
(2004)
J Cell Biol
, vol.165
, pp. 459-464
-
-
Ward, I.M.1
Reina-San-Martin, B.2
Olaru, A.3
Minn, K.4
Tamada, K.5
Lau, J.S.6
-
124
-
-
4544362838
-
The mechanism of non-homologous end-joining: A synopsis of synapsis
-
Weterings E, van Gent DC. (2004). The mechanism of non-homologous end-joining: a synopsis of synapsis. DNA Repair (Amst) 3: 1425-1435.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1425-1435
-
-
Weterings, E.1
van Gent, D.C.2
-
125
-
-
0030811523
-
Yeast DNA ligase IV mediates non-homologous DNA end joining
-
Wilson TE, Grawunder U, Lieber MR. (1997). Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature 388: 495-498.
-
(1997)
Nature
, vol.388
, pp. 495-498
-
-
Wilson, T.E.1
Grawunder, U.2
Lieber, M.R.3
-
126
-
-
36949020443
-
Interplay between Cernunnos/XLF and NHEJ proteins at DNA ends in the cell
-
e-pub ahead of print: 24 August
-
Wu PY, Frit P, Malivert L, Revy P, Biard D, Salles B et al. (2007). Interplay between Cernunnos/XLF and NHEJ proteins at DNA ends in the cell. J biol Chem; e-pub ahead of print: 24 August 2007.
-
(2007)
J biol Chem
-
-
Wu, P.Y.1
Frit, P.2
Malivert, L.3
Revy, P.4
Biard, D.5
Salles, B.6
-
127
-
-
0031278299
-
Ig Sgamma3 DNA-specific double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination
-
Wuerffel RA, Du J, Thompson RJ, Kenter AL. (1997). Ig Sgamma3 DNA-specific double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination. J Immunol 159: 4139-4144.
-
(1997)
J Immunol
, vol.159
, pp. 4139-4144
-
-
Wuerffel, R.A.1
Du, J.2
Thompson, R.J.3
Kenter, A.L.4
-
128
-
-
33845604556
-
DNA double-strand break repair: All's well that ends well
-
Wyman C, Kanaar R. (2006). DNA double-strand break repair: all's well that ends well. Annu Rev Genet 40: 363-383.
-
(2006)
Annu Rev Genet
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
129
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical end-joining pathway
-
Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M et al. (2007). IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 449: 478-483.
-
(2007)
Nature
, vol.449
, pp. 478-483
-
-
Yan, C.T.1
Boboila, C.2
Souza, E.K.3
Franco, S.4
Hickernell, T.R.5
Murphy, M.6
-
130
-
-
34248400443
-
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
-
Zha S, Alt FW, Cheng HL, Brush JW, Li G. (2007). Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells. Proc Natl Acad Sci USA 104: 4518-4523.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4518-4523
-
-
Zha, S.1
Alt, F.W.2
Cheng, H.L.3
Brush, J.W.4
Li, G.5
-
131
-
-
4744373121
-
Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response
-
Zhang X, Succi J, Feng Z, Prithivirajsingh S, Story MD, Legerski RJ. (2004). Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol 24: 9207-9220.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9207-9220
-
-
Zhang, X.1
Succi, J.2
Feng, Z.3
Prithivirajsingh, S.4
Story, M.D.5
Legerski, R.J.6
|