DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair

Nature

Volumn 471, Issue 7337, 2011, Pages 240-246

  Gao, Yankun ^a   Katyal, Sachin ^a   Lee, Youngsoo ^a   Zhao, Jingfeng ^a   Rehg, Jerold E ^a   Russell, Helen R ^a   McKinnon, Peter J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE III; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

CELL ORGANELLE; EMBRYO; ENZYME ACTIVITY; HOMEOSTASIS; MITOCHONDRIAL DNA; MUSCLE; NERVOUS SYSTEM; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; CELL DISRUPTION; CONTROLLED STUDY; DNA REPAIR; FEMALE; GENE INACTIVATION; HEART FAILURE; HEART FUNCTION; HEART MUSCLE; HOMEOSTASIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ATAXIA; BIOCATALYSIS; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; DNA LIGASES; DNA REPAIR; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; GENES, ESSENTIAL; HEART; INTERNEURONS; MICE; MITOCHONDRIA; MUSCLE, SKELETAL; MYOCARDIUM; NERVOUS SYSTEM; PHENOTYPE;

MAMMALIA; MURINAE;

EID: 79952368682     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09773     Document Type: Article

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