-
1
-
-
0004146634
-
-
Cambridge University Press Cambridge, UK
-
E. Schroedinger What is Life? 1944 Cambridge University Press Cambridge, UK
-
(1944)
What Is Life?
-
-
Schroedinger, E.1
-
2
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
T. Lindahl Instability and decay of the primary structure of DNA Nature 362 1993 709 715
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
3
-
-
0142150241
-
Harmful health effects of cigarette smoking
-
S.K. Das Harmful health effects of cigarette smoking Mol. Cell. Biochem. 253 2003 159 165
-
(2003)
Mol. Cell. Biochem.
, vol.253
, pp. 159-165
-
-
Das, S.K.1
-
5
-
-
0242268065
-
Mammalian DNA base excision repair proteins: Their interactions and role in repair of oxidative DNA damage
-
T. Izumi, L.R. Wiederhold, G. Roy, R. Roy, A. Jaiswal, K.K. Bhakat, S. Mitra, and T.K. Hazra Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage Toxicology 193 2003 43 65
-
(2003)
Toxicology
, vol.193
, pp. 43-65
-
-
Izumi, T.1
Wiederhold, L.R.2
Roy, G.3
Roy, R.4
Jaiswal, A.5
Bhakat, K.K.6
Mitra, S.7
Hazra, T.K.8
-
6
-
-
0348140585
-
Abasic sites in DNA: Repair and biological consequences in Saccharomyces cerevisiae
-
S. Boiteux, and M. Guillet Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae DNA Repair (Amsterdam) 3 2004 1 12
-
(2004)
DNA Repair (Amsterdam)
, vol.3
, pp. 1-12
-
-
Boiteux, S.1
Guillet, M.2
-
7
-
-
0141925645
-
Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses
-
R.W. Sobol, M. Kartalou, K.H. Almeida, D.F. Joyce, B.P. Engelward, J.K. Horton, R. Prasad, L.D. Samson, and S.H. Wilson Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses J. Biol. Chem. 278 2003 39951 39959
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39951-39959
-
-
Sobol, R.W.1
Kartalou, M.2
Almeida, K.H.3
Joyce, D.F.4
Engelward, B.P.5
Horton, J.K.6
Prasad, R.7
Samson, L.D.8
Wilson, S.H.9
-
8
-
-
0030035663
-
Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase
-
B. Kavli, G. Slupphaug, C.D. Mol, A.S. Arvai, S.B. Peterson, J.A. Tainer, and H.E. Krokan Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase EMBO J. 15 1996 3442 3447
-
(1996)
EMBO J.
, vol.15
, pp. 3442-3447
-
-
Kavli, B.1
Slupphaug, G.2
Mol, C.D.3
Arvai, A.S.4
Peterson, S.B.5
Tainer, J.A.6
Krokan, H.E.7
-
9
-
-
2942532239
-
Modulation of the 5′-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1
-
D. Wong, and B. Demple Modulation of the 5′-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1 J. Biol. Chem. 279 2004 25268 25275
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25268-25275
-
-
Wong, D.1
Demple, B.2
-
11
-
-
0035940441
-
Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair
-
I.I. Dianova, V.A. Bohr, and G.L. Dianov Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair Biochemistry 40 2001 12639 12644
-
(2001)
Biochemistry
, vol.40
, pp. 12639-12644
-
-
Dianova, I.I.1
Bohr, V.A.2
Dianov, G.L.3
-
12
-
-
0342350255
-
Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair
-
D.S. Levin, A.E. McKenna, T.A. Motycka, Y. Matsumoto, and A.E. Tomkinson Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair Curr. Biol. 10 2000 919 922
-
(2000)
Curr. Biol.
, vol.10
, pp. 919-922
-
-
Levin, D.S.1
McKenna, A.E.2
Motycka, T.A.3
Matsumoto, Y.4
Tomkinson, A.E.5
-
13
-
-
0034733694
-
Base excision repair in yeast and mammals
-
A. Memisoglu, and L. Samson Base excision repair in yeast and mammals Mutat. Res. 451 2000 39 51
-
(2000)
Mutat. Res.
, vol.451
, pp. 39-51
-
-
Memisoglu, A.1
Samson, L.2
-
16
-
-
0028604549
-
Unified catalytic mechanism for DNA glycosylases
-
M.L. Dodson, M.L. Michaels, and R.S. Lloyd Unified catalytic mechanism for DNA glycosylases J. Biol. Chem. 269 1994 32709 32712
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32709-32712
-
-
Dodson, M.L.1
Michaels, M.L.2
Lloyd, R.S.3
-
17
-
-
0029013243
-
The catalytic mechanism of Fpg protein. Evidence for a Schiff base intermediate and amino terminus localization of the catalytic site
-
J. Tchou, and A.P. Grollman The catalytic mechanism of Fpg protein. Evidence for a Schiff base intermediate and amino terminus localization of the catalytic site J. Biol. Chem. 270 1995 11671 11677
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11671-11677
-
-
Tchou, J.1
Grollman, A.P.2
-
18
-
-
0036294464
-
Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM
-
J.C. Fromme, and G.L. Verdine Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM Nat. Struct. Biol. 9 2002 544 552
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 544-552
-
-
Fromme, J.C.1
Verdine, G.L.2
-
19
-
-
0037925462
-
Structure of a trapped endonuclease III-DNA covalent intermediate
-
J.C. Fromme, and G.L. Verdine Structure of a trapped endonuclease III-DNA covalent intermediate EMBO J. 22 2003 3461 3471
-
(2003)
EMBO J.
, vol.22
, pp. 3461-3471
-
-
Fromme, J.C.1
Verdine, G.L.2
-
20
-
-
0346319010
-
Product-assisted catalysis in base-excision DNA repair
-
J.C. Fromme, S.D. Bruner, W. Yang, M. Karplus, and G.L. Verdine Product-assisted catalysis in base-excision DNA repair Nat. Struct. Biol. 10 2003 204 211
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 204-211
-
-
Fromme, J.C.1
Bruner, S.D.2
Yang, W.3
Karplus, M.4
Verdine, G.L.5
-
21
-
-
0037205477
-
Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA
-
R. Gilboa, D.O. Zharkov, G. Golan, A.S. Fernandes, S.E. Gerchman, E. Matz, J.H. Kycia, A.P. Grollman, and G. Shoham Structure of formamidopyrimidine- DNA glycosylase covalently complexed to DNA J. Biol. Chem. 277 2002 19811 19816
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19811-19816
-
-
Gilboa, R.1
Zharkov, D.O.2
Golan, G.3
Fernandes, A.S.4
Gerchman, S.E.5
Matz, E.6
Kycia, J.H.7
Grollman, A.P.8
Shoham, G.9
-
22
-
-
0037084112
-
Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate
-
D.O. Zharkov, G. Golan, R. Gilboa, A.S. Fernandes, S.E. Gerchman, J.H. Kycia, R.A. Rieger, A.P. Grollman, and G. Shoham Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate EMBO J. 21 2002 789 800
-
(2002)
EMBO J.
, vol.21
, pp. 789-800
-
-
Zharkov, D.O.1
Golan, G.2
Gilboa, R.3
Fernandes, A.S.4
Gerchman, S.E.5
Kycia, J.H.6
Rieger, R.A.7
Grollman, A.P.8
Shoham, G.9
-
23
-
-
0032534053
-
Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA
-
S.D. Williams, and S.S. David Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA Nucl. Acids Res. 26 1998 5123 5133
-
(1998)
Nucl. Acids Res.
, vol.26
, pp. 5123-5133
-
-
Williams, S.D.1
David, S.S.2
-
24
-
-
3543029188
-
DNA binding and nucleotide flipping by the human DNA repair protein AGT
-
D.S. Daniels, T.T. Woo, K.X. Luu, D.M. Noll, N.D. Clarke, A.E. Pegg, and J.A. Tainer DNA binding and nucleotide flipping by the human DNA repair protein AGT Nat. Struct. Mol. Biol. 11 2004 714 720
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 714-720
-
-
Daniels, D.S.1
Woo, T.T.2
Luu, K.X.3
Noll, D.M.4
Clarke, N.D.5
Pegg, A.E.6
Tainer, J.A.7
-
25
-
-
0034651873
-
DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA
-
T. Hollis, Y. Ichikawa, and T. Ellenberger DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA EMBO J. 19 2000 758 766
-
(2000)
EMBO J.
, vol.19
, pp. 758-766
-
-
Hollis, T.1
Ichikawa, Y.2
Ellenberger, T.3
-
26
-
-
0034708226
-
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
-
S.D. Bruner, D.P. Norman, and G.L. Verdine Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA Nature 403 2000 859 866
-
(2000)
Nature
, vol.403
, pp. 859-866
-
-
Bruner, S.D.1
Norman, D.P.2
Verdine, G.L.3
-
27
-
-
0032498302
-
Crystal structure of a G:T/U mismatch-specific DNA glycosylase: Mismatch recognition by complementary-strand interactions
-
T.E. Barrett, R. Savva, G. Panayotou, T. Barlow, T. Brown, J. Jiricny, and L.H. Pearl Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions Cell 92 1998 117 129
-
(1998)
Cell
, vol.92
, pp. 117-129
-
-
Barrett, T.E.1
Savva, R.2
Panayotou, G.3
Barlow, T.4
Brown, T.5
Jiricny, J.6
Pearl, L.H.7
-
28
-
-
0032167424
-
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
-
S.S. Parikh, C.D. Mol, G. Slupphaug, S. Bharati, H.E. Krokan, and J.A. Tainer Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA EMBO J. 17 1998 5214 5226
-
(1998)
EMBO J.
, vol.17
, pp. 5214-5226
-
-
Parikh, S.S.1
Mol, C.D.2
Slupphaug, G.3
Bharati, S.4
Krokan, H.E.5
Tainer, J.A.6
-
29
-
-
0034719372
-
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
-
C.D. Mol, T. Izumi, S. Mitra, and J.A. Tainer DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination Nature 403 2000 451 456
-
(2000)
Nature
, vol.403
, pp. 451-456
-
-
Mol, C.D.1
Izumi, T.2
Mitra, S.3
Tainer, J.A.4
-
30
-
-
0033529716
-
Structure of the DNA repair enzyme endonuclease IV and its DNA complex: Double-nucleotide flipping at abasic sites and three-metal-ion catalysis
-
D.J. Hosfield, Y. Guan, B.J. Haas, R.P. Cunningham, and J.A. Tainer Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis Cell 98 1999 397 408
-
(1999)
Cell
, vol.98
, pp. 397-408
-
-
Hosfield, D.J.1
Guan, Y.2
Haas, B.J.3
Cunningham, R.P.4
Tainer, J.A.5
-
31
-
-
0034625082
-
Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
-
S.S. Parikh, G. Walcher, G.D. Jones, G. Slupphaug, H.E. Krokan, G.M. Blackburn, and J.A. Tainer Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects Proc. Natl. Acad. Sci. U.S.A. 97 2000 5083 5088
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 5083-5088
-
-
Parikh, S.S.1
Walcher, G.2
Jones, G.D.3
Slupphaug, G.4
Krokan, H.E.5
Blackburn, G.M.6
Tainer, J.A.7
-
32
-
-
0029119097
-
Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure
-
M.M. Thayer, H. Ahern, D. Xing, R.P. Cunningham, and J.A. Tainer Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure EMBO J. 14 1995 4108 4120
-
(1995)
EMBO J.
, vol.14
, pp. 4108-4120
-
-
Thayer, M.M.1
Ahern, H.2
Xing, D.3
Cunningham, R.P.4
Tainer, J.A.5
-
33
-
-
16044372779
-
Three-dimensional structure of a DNA repair enzyme, 3-methyladenine DNA glycosylase II, from Escherichia coli
-
Y. Yamagata, M. Kato, K. Odawara, Y. Tokuno, Y. Nakashima, N. Matsushima, K. Yasumura, K. Tomita, K. Ihara, Y. Fujii, Y. Nakabeppu, M. Sekiguchi, and S. Fujii Three-dimensional structure of a DNA repair enzyme, 3-methyladenine DNA glycosylase II, from Escherichia coli Cell 86 1996 311 319
-
(1996)
Cell
, vol.86
, pp. 311-319
-
-
Yamagata, Y.1
Kato, M.2
Odawara, K.3
Tokuno, Y.4
Nakashima, Y.5
Matsushima, N.6
Yasumura, K.7
Tomita, K.8
Ihara, K.9
Fujii, Y.10
Nakabeppu, Y.11
Sekiguchi, M.12
Fujii, S.13
-
35
-
-
0141754009
-
Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
-
B.F. Eichman, E.J. O'Rourke, J.P. Radicella, and T. Ellenberger Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases EMBO J. 22 2003 4898 4909
-
(2003)
EMBO J.
, vol.22
, pp. 4898-4909
-
-
Eichman, B.F.1
O'Rourke, E.J.2
Radicella, J.P.3
Ellenberger, T.4
-
36
-
-
0028863468
-
Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: Structural basis for damaged DNA recognition
-
D.G. Vassylyev, T. Kashiwagi, Y. Mikami, M. Ariyoshi, S. Iwai, E. Ohtsuka, and K. Morikawa Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognition Cell 83 1995 773 782
-
(1995)
Cell
, vol.83
, pp. 773-782
-
-
Vassylyev, D.G.1
Kashiwagi, T.2
Mikami, Y.3
Ariyoshi, M.4
Iwai, S.5
Ohtsuka, E.6
Morikawa, K.7
-
37
-
-
0036305835
-
Structure and activity of a thermostable thymine-DNA glycosylase: Evidence for base twisting to remove mismatched normal DNA bases
-
C.D. Mol, A.S. Arvai, T.J. Begley, R.P. Cunningham, and J.A. Tainer Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases J. Mol. Biol. 315 2002 373 384
-
(2002)
J. Mol. Biol.
, vol.315
, pp. 373-384
-
-
Mol, C.D.1
Arvai, A.S.2
Begley, T.J.3
Cunningham, R.P.4
Tainer, J.A.5
-
38
-
-
0030602838
-
Structural basis for the excision repair of alkylation-damaged DNA
-
J. Labahn, O.D. Scharer, A. Long, K. Ezaz-Nikpay, G.L. Verdine, and T.E. Ellenberger Structural basis for the excision repair of alkylation-damaged DNA Cell 86 1996 321 329
-
(1996)
Cell
, vol.86
, pp. 321-329
-
-
Labahn, J.1
Scharer, O.D.2
Long, A.3
Ezaz-Nikpay, K.4
Verdine, G.L.5
Ellenberger, T.E.6
-
39
-
-
0031763884
-
MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily
-
Y. Guan, R.C. Manuel, A.S. Arvai, S.S. Parikh, C.D. Mol, J.H. Miller, S. Lloyd, and J.A. Tainer MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily Nat. Struct. Biol. 5 1998 1058 1064
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 1058-1064
-
-
Guan, Y.1
Manuel, R.C.2
Arvai, A.S.3
Parikh, S.S.4
Mol, C.D.5
Miller, J.H.6
Lloyd, S.7
Tainer, J.A.8
-
40
-
-
0036730599
-
3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member
-
A.C. Drohat, K. Kwon, D.J. Krosky, and J.T. Stivers 3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member Nat. Struct. Biol. 9 2002 659 664
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 659-664
-
-
Drohat, A.C.1
Kwon, K.2
Krosky, D.J.3
Stivers, J.T.4
-
41
-
-
1342304229
-
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
-
J.C. Fromme, A. Banerjee, S.J. Huang, and G.L. Verdine Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase Nature 427 2004 652 656
-
(2004)
Nature
, vol.427
, pp. 652-656
-
-
Fromme, J.C.1
Banerjee, A.2
Huang, S.J.3
Verdine, G.L.4
-
42
-
-
11844306632
-
A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
-
G.M. Lingaraju, A.A. Sartori, D. Kostrewa, A.E. Prota, J. Jiricny, and F.K. Winkler A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure Structure (Cambridge) 13 2005 87 98
-
(2005)
Structure (Cambridge)
, vol.13
, pp. 87-98
-
-
Lingaraju, G.M.1
Sartori, A.A.2
Kostrewa, D.3
Prota, A.E.4
Jiricny, J.5
Winkler, F.K.6
-
43
-
-
0032538337
-
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: Mechanisms for nucleotide flipping and base excision
-
A.Y. Lau, O.D. Scharer, L. Samson, G.L. Verdine, and T. Ellenberger Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision Cell 95 1998 249 258
-
(1998)
Cell
, vol.95
, pp. 249-258
-
-
Lau, A.Y.1
Scharer, O.D.2
Samson, L.3
Verdine, G.L.4
Ellenberger, T.5
-
44
-
-
0029929070
-
The helix-hairpin-helix DNA-binding motif: A structural basis for non-sequence-specific recognition of DNA
-
A.J. Doherty, L.C. Serpell, and C.P. Ponting The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA Nucl. Acids Res. 24 1996 2488 2497
-
(1996)
Nucl. Acids Res.
, vol.24
, pp. 2488-2497
-
-
Doherty, A.J.1
Serpell, L.C.2
Ponting, C.P.3
-
45
-
-
0032475933
-
Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: Coupling DNA and PCNA binding to FEN-1 activity
-
D.J. Hosfield, C.D. Mol, B. Shen, and J.A. Tainer Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity Cell 95 1998 135 146
-
(1998)
Cell
, vol.95
, pp. 135-146
-
-
Hosfield, D.J.1
Mol, C.D.2
Shen, B.3
Tainer, J.A.4
-
46
-
-
0034254724
-
Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8
-
M. Sugahara, T. Mikawa, T. Kumasaka, M. Yamamoto, R. Kato, K. Fukuyama, Y. Inoue, and S. Kuramitsu Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8 EMBO J. 19 2000 3857 3869
-
(2000)
EMBO J.
, vol.19
, pp. 3857-3869
-
-
Sugahara, M.1
Mikawa, T.2
Kumasaka, T.3
Yamamoto, M.4
Kato, R.5
Fukuyama, K.6
Inoue, Y.7
Kuramitsu, S.8
-
47
-
-
0037124320
-
Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA
-
L. Serre, K. Pereira de Jesus, S. Boiteux, C. Zelwer, and B. Castaing Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA EMBO J. 21 2002 2854 2865
-
(2002)
EMBO J.
, vol.21
, pp. 2854-2865
-
-
Serre, L.1
Pereira De Jesus, K.2
Boiteux, S.3
Zelwer, C.4
Castaing, B.5
-
48
-
-
0346435086
-
DNA lesion recognition by the bacterial repair enzyme MutM
-
J.C. Fromme, and G.L. Verdine DNA lesion recognition by the bacterial repair enzyme MutM J. Biol. Chem. 278 2003 51543 51548
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51543-51548
-
-
Fromme, J.C.1
Verdine, G.L.2
-
49
-
-
3142702720
-
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity
-
S. Doublie, V. Bandaru, J.P. Bond, and S.S. Wallace The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity Proc. Natl. Acad. Sci. U.S.A. 101 2004 10284 10289
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10284-10289
-
-
Doublie, S.1
Bandaru, V.2
Bond, J.P.3
Wallace, S.S.4
-
50
-
-
8744262953
-
Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein
-
A. Das, L. Rajagopalan, V.S. Mathura, S.J. Rigby, S. Mitra, and T.K. Hazra Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein J. Biol. Chem. 279 2004 47132 47138
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47132-47138
-
-
Das, A.1
Rajagopalan, L.2
Mathura, V.S.3
Rigby, S.J.4
Mitra, S.5
Hazra, T.K.6
-
51
-
-
0347379928
-
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
-
H. Dou, S. Mitra, and T.K. Hazra Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2 J. Biol. Chem. 278 2003 49679 49684
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49679-49684
-
-
Dou, H.1
Mitra, S.2
Hazra, T.K.3
-
52
-
-
3242710517
-
AP endonuclease-independent DNA base excision repair in human cells
-
L. Wiederhold, J.B. Leppard, P. Kedar, F. Karimi-Busheri, A. Rasouli-Nia, M. Weinfeld, A.E. Tomkinson, T. Izumi, R. Prasad, S.H. Wilson, S. Mitra, and T.K. Hazra AP endonuclease-independent DNA base excision repair in human cells Mol. Cell 15 2004 209 220
-
(2004)
Mol. Cell
, vol.15
, pp. 209-220
-
-
Wiederhold, L.1
Leppard, J.B.2
Kedar, P.3
Karimi-Busheri, F.4
Rasouli-Nia, A.5
Weinfeld, M.6
Tomkinson, A.E.7
Izumi, T.8
Prasad, R.9
Wilson, S.H.10
Mitra, S.11
Hazra, T.K.12
-
53
-
-
0037509930
-
Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions
-
A. Masaoka, M. Matsubara, R. Hasegawa, T. Tanaka, S. Kurisu, H. Terato, Y. Ohyama, N. Karino, A. Matsuda, and H. Ide Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions Biochemistry 42 2003 5003 5012
-
(2003)
Biochemistry
, vol.42
, pp. 5003-5012
-
-
Masaoka, A.1
Matsubara, M.2
Hasegawa, R.3
Tanaka, T.4
Kurisu, S.5
Terato, H.6
Ohyama, Y.7
Karino, N.8
Matsuda, A.9
Ide, H.10
-
54
-
-
0038771139
-
Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1
-
J.E. Wibley, T.R. Waters, K. Haushalter, G.L. Verdine, and L.H. Pearl Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1 Mol. Cell 11 2003 1647 1659
-
(2003)
Mol. Cell
, vol.11
, pp. 1647-1659
-
-
Wibley, J.E.1
Waters, T.R.2
Haushalter, K.3
Verdine, G.L.4
Pearl, L.H.5
-
55
-
-
0028934537
-
Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis
-
C.D. Mol, A.S. Arvai, G. Slupphaug, B. Kavli, I. Alseth, H.E. Krokan, and J.A. Tainer Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis Cell 80 1995 869 878
-
(1995)
Cell
, vol.80
, pp. 869-878
-
-
Mol, C.D.1
Arvai, A.S.2
Slupphaug, G.3
Kavli, B.4
Alseth, I.5
Krokan, H.E.6
Tainer, J.A.7
-
57
-
-
0037449138
-
Energetics of lesion recognition by a DNA repair protein: Thermodynamic characterization of formamidopyrimidine-glycosylase (Fpg) interactions with damaged DNA duplexes
-
C.A. Minetti, D.P. Remeta, D.O. Zharkov, G.E. Plum, F. Johnson, A.P. Grollman, and K.J. Breslauer Energetics of lesion recognition by a DNA repair protein: thermodynamic characterization of formamidopyrimidine-glycosylase (Fpg) interactions with damaged DNA duplexes J. Mol. Biol. 328 2003 1047 1060
-
(2003)
J. Mol. Biol.
, vol.328
, pp. 1047-1060
-
-
Minetti, C.A.1
Remeta, D.P.2
Zharkov, D.O.3
Plum, G.E.4
Johnson, F.5
Grollman, A.P.6
Breslauer, K.J.7
-
58
-
-
0042342532
-
A mechanistic perspective on the chemistry of DNA repair glycosylases
-
J.T. Stivers, and Y.L. Jiang A mechanistic perspective on the chemistry of DNA repair glycosylases Chem. Rev. 103 2003 2729 2759
-
(2003)
Chem. Rev.
, vol.103
, pp. 2729-2759
-
-
Stivers, J.T.1
Jiang, Y.L.2
-
59
-
-
0036829538
-
A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue
-
M. Takao, S.I. Kanno, K. Kobayashi, Q.M. Zhang, S. Yonei, G.T. Van Der Horst, and A. Yasui A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue J. Biol. Chem. 277 2002 42205 42213
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42205-42213
-
-
Takao, M.1
Kanno, S.I.2
Kobayashi, K.3
Zhang, Q.M.4
Yonei, S.5
Van Der Horst, G.T.6
Yasui, A.7
-
60
-
-
0030816108
-
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
-
J.P. Radicella, C. Dherin, C. Desmaze, M.S. Fox, and S. Boiteux Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae Proc. Natl. Acad. Sci. U.S.A. 94 1997 8010 8015
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 8010-8015
-
-
Radicella, J.P.1
Dherin, C.2
Desmaze, C.3
Fox, M.S.4
Boiteux, S.5
-
61
-
-
0032555571
-
Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease. III. Direct identification of Lys-212 as the active nucleophilic residue
-
S. Ikeda, T. Biswas, R. Roy, T. Izumi, I. Boldogh, A. Kurosky, A.H. Sarker, S. Seki, and S. Mitra Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease. III. Direct identification of Lys-212 as the active nucleophilic residue J. Biol. Chem. 273 1998 21585 21593
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21585-21593
-
-
Ikeda, S.1
Biswas, T.2
Roy, R.3
Izumi, T.4
Boldogh, I.5
Kurosky, A.6
Sarker, A.H.7
Seki, S.8
Mitra, S.9
-
62
-
-
0037162995
-
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions
-
T.K. Hazra, Y.W. Kow, Z. Hatahet, B. Imhoff, I. Boldogh, S.K. Mokkapati, S. Mitra, and T. Izumi Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions J. Biol. Chem. 277 2002 30417 30420
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30417-30420
-
-
Hazra, T.K.1
Kow, Y.W.2
Hatahet, Z.3
Imhoff, B.4
Boldogh, I.5
Mokkapati, S.K.6
Mitra, S.7
Izumi, T.8
-
63
-
-
0037133684
-
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
-
T.K. Hazra, T. Izumi, I. Boldogh, B. Imhoff, Y.W. Kow, P. Jaruga, M. Dizdaroglu, and S. Mitra Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA Proc. Natl. Acad. Sci. U.S.A. 99 2002 3523 3528
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 3523-3528
-
-
Hazra, T.K.1
Izumi, T.2
Boldogh, I.3
Imhoff, B.4
Kow, Y.W.5
Jaruga, P.6
Dizdaroglu, M.7
Mitra, S.8
-
64
-
-
0030703177
-
Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
-
M. Bjoras, L. Luna, B. Johnsen, E. Hoff, T. Haug, T. Rognes, and E. Seeberg Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites EMBO J. 16 1997 6314 6322
-
(1997)
EMBO J.
, vol.16
, pp. 6314-6322
-
-
Bjoras, M.1
Luna, L.2
Johnsen, B.3
Hoff, E.4
Haug, T.5
Rognes, T.6
Seeberg, E.7
-
65
-
-
0036290411
-
Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase
-
M. Bjoras, E. Seeberg, L. Luna, L.H. Pearl, and T.E. Barrett Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase J. Mol. Biol. 317 2002 171 177
-
(2002)
J. Mol. Biol.
, vol.317
, pp. 171-177
-
-
Bjoras, M.1
Seeberg, E.2
Luna, L.3
Pearl, L.H.4
Barrett, T.E.5
-
66
-
-
1342266756
-
The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk
-
J. Park, L. Chen, M.S. Tockman, A. Elahi, and P. Lazarus The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk Pharmacogenetics 14 2004 103 109
-
(2004)
Pharmacogenetics
, vol.14
, pp. 103-109
-
-
Park, J.1
Chen, L.2
Tockman, M.S.3
Elahi, A.4
Lazarus, P.5
-
67
-
-
0036117844
-
Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk
-
L. Le Marchand, T. Donlon, A. Lum-Jones, A. Seifried, and L.R. Wilkens Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk Cancer Epidemiol. Biomarkers Prev. 11 2002 409 412
-
(2002)
Cancer Epidemiol. Biomarkers Prev.
, vol.11
, pp. 409-412
-
-
Le Marchand, L.1
Donlon, T.2
Lum-Jones, A.3
Seifried, A.4
Wilkens, L.R.5
-
68
-
-
12344307152
-
Product inhibition and magnesium modulate the dual reaction mode of hOgg1
-
I. Morland, L. Luna, E. Gustad, E. Seeberg, and M. Bjoras Product inhibition and magnesium modulate the dual reaction mode of hOgg1 DNA Repair (Amsterdam) 4 2005 381 387
-
(2005)
DNA Repair (Amsterdam)
, vol.4
, pp. 381-387
-
-
Morland, I.1
Luna, L.2
Gustad, E.3
Seeberg, E.4
Bjoras, M.5
-
69
-
-
0026701365
-
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
-
M.L. Michaels, and J.H. Miller The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8- oxoguanine) J. Bacteriol. 174 1992 6321 6325
-
(1992)
J. Bacteriol.
, vol.174
, pp. 6321-6325
-
-
Michaels, M.L.1
Miller, J.H.2
-
70
-
-
0037459233
-
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: Complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E. coli enzymes
-
N.H. Chmiel, A.L. Livingston, and S.S. David Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E. coli enzymes J. Mol. Biol. 327 2003 431 443
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 431-443
-
-
Chmiel, N.H.1
Livingston, A.L.2
David, S.S.3
-
71
-
-
0035949687
-
Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
-
T. Tsuzuki, A. Egashira, H. Igarashi, T. Iwakuma, Y. Nakatsuru, Y. Tominaga, H. Kawate, K. Nakao, K. Nakamura, F. Ide, S. Kura, Y. Nakabeppu, M. Katsuki, T. Ishikawa, and M. Sekiguchi Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase Proc. Natl. Acad. Sci. U.S.A. 98 2001 11456 11461
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 11456-11461
-
-
Tsuzuki, T.1
Egashira, A.2
Igarashi, H.3
Iwakuma, T.4
Nakatsuru, Y.5
Tominaga, Y.6
Kawate, H.7
Nakao, K.8
Nakamura, K.9
Ide, F.10
Kura, S.11
Nakabeppu, Y.12
Katsuki, M.13
Ishikawa, T.14
Sekiguchi, M.15
-
72
-
-
0242363184
-
DNA-mediated charge transport for DNA repair
-
E.M. Boon, A.L. Livingston, N.H. Chmiel, S.S. David, and J.K. Barton DNA-mediated charge transport for DNA repair Proc. Natl. Acad. Sci. U.S.A. 100 2003 12543 12547
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 12543-12547
-
-
Boon, E.M.1
Livingston, A.L.2
Chmiel, N.H.3
David, S.S.4
Barton, J.K.5
-
73
-
-
0034610354
-
Role for lysine 142 in the excision of adenine from A:G mispairs by MutY DNA glycosylase of Escherichia coli
-
D.O. Zharkov, R. Gilboa, I. Yagil, J.H. Kycia, S.E. Gerchman, G. Shoham, and A.P. Grollman Role for lysine 142 in the excision of adenine from A:G mispairs by MutY DNA glycosylase of Escherichia coli Biochemistry 39 2000 14768 14778
-
(2000)
Biochemistry
, vol.39
, pp. 14768-14778
-
-
Zharkov, D.O.1
Gilboa, R.2
Yagil, I.3
Kycia, J.H.4
Gerchman, S.E.5
Shoham, G.6
Grollman, A.P.7
-
74
-
-
0042324507
-
Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product
-
M.A. Massiah, V. Saraswat, H.F. Azurmendi, and A.S. Mildvan Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product Biochemistry 42 2003 10140 10154
-
(2003)
Biochemistry
, vol.42
, pp. 10140-10154
-
-
Massiah, M.A.1
Saraswat, V.2
Azurmendi, H.F.3
Mildvan, A.S.4
-
75
-
-
0036478899
-
Inherited variants of MYH associated with somatic G:C → T:A mutations in colorectal tumors
-
N. Al-Tassan, N.H. Chmiel, J. Maynard, N. Fleming, A.L. Livingston, G.T. Williams, A.K. Hodges, D.R. Davies, S.S. David, J.R. Sampson, and J.P. Cheadle Inherited variants of MYH associated with somatic G:C → T:A mutations in colorectal tumors Nat. Genet. 30 2002 227 232
-
(2002)
Nat. Genet.
, vol.30
, pp. 227-232
-
-
Al-Tassan, N.1
Chmiel, N.H.2
Maynard, J.3
Fleming, N.4
Livingston, A.L.5
Williams, G.T.6
Hodges, A.K.7
Davies, D.R.8
David, S.S.9
Sampson, J.R.10
Cheadle, J.P.11
-
76
-
-
0030818650
-
Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein
-
A. Karakaya, P. Jaruga, V.A. Bohr, A.P. Grollman, and M. Dizdaroglu Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein Nucl. Acids Res. 25 1997 474 479
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 474-479
-
-
Karakaya, A.1
Jaruga, P.2
Bohr, V.A.3
Grollman, A.P.4
Dizdaroglu, M.5
-
77
-
-
0025871264
-
MutM, a protein that prevents G.C → T.A transversions, is formamidopyrimidine-DNA glycosylase
-
M.L. Michaels, L. Pham, C. Cruz, and J.H. Miller MutM, a protein that prevents G.C → T.A transversions, is formamidopyrimidine-DNA glycosylase Nucl. Acids Res. 19 1991 3629 3632
-
(1991)
Nucl. Acids Res.
, vol.19
, pp. 3629-3632
-
-
Michaels, M.L.1
Pham, L.2
Cruz, C.3
Miller, J.H.4
-
78
-
-
0142187125
-
Structural characterization of the Fpg family of DNA glycosylases
-
D.O. Zharkov, G. Shoham, and A.P. Grollman Structural characterization of the Fpg family of DNA glycosylases DNA Repair (Amsterdam) 2 2003 839 862
-
(2003)
DNA Repair (Amsterdam)
, vol.2
, pp. 839-862
-
-
Zharkov, D.O.1
Shoham, G.2
Grollman, A.P.3
-
79
-
-
6344223490
-
Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase
-
F. Coste, M. Ober, T. Carell, S. Boiteux, C. Zelwer, and B. Castaing Structural basis for the recognition of the FapydG lesion (2,6-diamino-4- hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase J. Biol. Chem. 279 2004 44074 44083
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44074-44083
-
-
Coste, F.1
Ober, M.2
Carell, T.3
Boiteux, S.4
Zelwer, C.5
Castaing, B.6
-
80
-
-
0018166688
-
Accumulation of small fragments of DNA in isolated HeLa cell nuclei due to transient incorporation of dUMP
-
E. Wist, O. Unhjem, and H. Krokan Accumulation of small fragments of DNA in isolated HeLa cell nuclei due to transient incorporation of dUMP Biochim. Biophys. Acta 520 1978 253 270
-
(1978)
Biochim. Biophys. Acta
, vol.520
, pp. 253-270
-
-
Wist, E.1
Unhjem, O.2
Krokan, H.3
-
81
-
-
0013608322
-
Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA
-
B.K. Tye, P.O. Nyman, I.R. Lehman, S. Hochhauser, and B. Weiss Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA Proc. Natl. Acad. Sci. U.S.A. 74 1977 154 157
-
(1977)
Proc. Natl. Acad. Sci. U.S.A.
, vol.74
, pp. 154-157
-
-
Tye, B.K.1
Nyman, P.O.2
Lehman, I.R.3
Hochhauser, S.4
Weiss, B.5
-
82
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
S.K. Petersen-Mahrt, R.S. Harris, and M.S. Neuberger AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification Nature 418 2002 99 103
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
83
-
-
0037076208
-
AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization
-
C. Rada, J.M. Jarvis, and C. Milstein AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization Proc. Natl. Acad. Sci. U.S.A. 99 2002 7003 7008
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 7003-7008
-
-
Rada, C.1
Jarvis, J.M.2
Milstein, C.3
-
84
-
-
0142092610
-
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
-
K. Imai, G. Slupphaug, W.I. Lee, P. Revy, S. Nonoyama, N. Catalan, L. Yel, M. Forveille, B. Kavli, H.E. Krokan, H.D. Ochs, A. Fischer, and A. Durandy Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination Nat. Immunol. 4 2003 1023 1028
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1023-1028
-
-
Imai, K.1
Slupphaug, G.2
Lee, W.I.3
Revy, P.4
Nonoyama, S.5
Catalan, N.6
Yel, L.7
Forveille, M.8
Kavli, B.9
Krokan, H.E.10
Ochs, H.D.11
Fischer, A.12
Durandy, A.13
-
85
-
-
0041639515
-
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas
-
H. Nilsen, G. Stamp, S. Andersen, G. Hrivnak, H.E. Krokan, T. Lindahl, and D.E. Barnes Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas Oncogene 22 2003 5381 5386
-
(2003)
Oncogene
, vol.22
, pp. 5381-5386
-
-
Nilsen, H.1
Stamp, G.2
Andersen, S.3
Hrivnak, G.4
Krokan, H.E.5
Lindahl, T.6
Barnes, D.E.7
-
86
-
-
18644363009
-
HUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
-
B. Kavli, O. Sundheim, M. Akbari, M. Otterlei, H. Nilsen, F. Skorpen, P.A. Aas, L. Hagen, H.E. Krokan, and G. Slupphaug hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup J. Biol. Chem. 277 2002 39926 39936
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39926-39936
-
-
Kavli, B.1
Sundheim, O.2
Akbari, M.3
Otterlei, M.4
Nilsen, H.5
Skorpen, F.6
Aas, P.A.7
Hagen, L.8
Krokan, H.E.9
Slupphaug, G.10
-
87
-
-
0019306430
-
Uracil DNA-glycosylase. Purification and properties of this enzyme isolated from blast cells of acute myelocytic leukemia patients
-
S.J. Caradonna, and Y.C. Cheng Uracil DNA-glycosylase. Purification and properties of this enzyme isolated from blast cells of acute myelocytic leukemia patients J. Biol. Chem. 255 1980 2293 2300
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 2293-2300
-
-
Caradonna, S.J.1
Cheng, Y.C.2
-
88
-
-
0020478598
-
Properties of purified uracil-DNA glycosylase from calf thymus. An in vitro study using synthetic DNA-like substrates
-
M. Talpaert-Borle, F. Campagnari, and D.M. Creissen Properties of purified uracil-DNA glycosylase from calf thymus. An in vitro study using synthetic DNA-like substrates J. Biol. Chem. 257 1982 1208 1214
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 1208-1214
-
-
Talpaert-Borle, M.1
Campagnari, F.2
Creissen, D.M.3
-
89
-
-
0030841051
-
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
-
H. Nilsen, M. Otterlei, T. Haug, K. Solum, T.A. Nagelhus, F. Skorpen, and H.E. Krokan Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene Nucl. Acids Res. 25 1997 750 755
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 750-755
-
-
Nilsen, H.1
Otterlei, M.2
Haug, T.3
Solum, K.4
Nagelhus, T.A.5
Skorpen, F.6
Krokan, H.E.7
-
90
-
-
0028959237
-
The structural basis of specific base-excision repair by uracil-DNA glycosylase
-
R. Savva, K. McAuley-Hecht, T. Brown, and L. Pearl The structural basis of specific base-excision repair by uracil-DNA glycosylase Nature 373 1995 487 493
-
(1995)
Nature
, vol.373
, pp. 487-493
-
-
Savva, R.1
McAuley-Hecht, K.2
Brown, T.3
Pearl, L.4
-
91
-
-
0029904839
-
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
-
G. Slupphaug, C.D. Mol, B. Kavli, A.S. Arvai, H.E. Krokan, and J.A. Tainer A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA Nature 384 1996 87 92
-
(1996)
Nature
, vol.384
, pp. 87-92
-
-
Slupphaug, G.1
Mol, C.D.2
Kavli, B.3
Arvai, A.S.4
Krokan, H.E.5
Tainer, J.A.6
-
92
-
-
0033120232
-
Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: Structure and glycosylase mechanism revisited
-
G. Xiao, M. Tordova, J. Jagadeesh, A.C. Drohat, J.T. Stivers, and G.L. Gilliland Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited Proteins 35 1999 13 24
-
(1999)
Proteins
, vol.35
, pp. 13-24
-
-
Xiao, G.1
Tordova, M.2
Jagadeesh, J.3
Drohat, A.C.4
Stivers, J.T.5
Gilliland, G.L.6
-
93
-
-
0042568932
-
The structure of uracil-DNA glycosylase from Atlantic cod (Gadus morhua) reveals cold-adaptation features
-
I. Leiros, E. Moe, O. Lanes, A.O. Smalas, and N.P. Willassen The structure of uracil-DNA glycosylase from Atlantic cod (Gadus morhua) reveals cold-adaptation features Acta Crystallogr. D: Biol. Crystallogr. 59 2003 1357 1365
-
(2003)
Acta Crystallogr. D: Biol. Crystallogr.
, vol.59
, pp. 1357-1365
-
-
Leiros, I.1
Moe, E.2
Lanes, O.3
Smalas, A.O.4
Willassen, N.P.5
-
94
-
-
0037205473
-
Presteady-state analysis of a single catalytic turnover by Escherichia coli uracil-DNA glycosylase reveals a "pinch-pull-push" mechanism
-
I. Wong, A.J. Lundquist, A.S. Bernards, and D.W. Mosbaugh Presteady-state analysis of a single catalytic turnover by Escherichia coli uracil-DNA glycosylase reveals a "pinch-pull-push" mechanism J. Biol. Chem. 277 2002 19424 19432
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19424-19432
-
-
Wong, I.1
Lundquist, A.J.2
Bernards, A.S.3
Mosbaugh, D.W.4
-
95
-
-
0034734383
-
Structure and function in the uracil-DNA glycosylase superfamily
-
L.H. Pearl Structure and function in the uracil-DNA glycosylase superfamily Mutat. Res. 460 2000 165 181
-
(2000)
Mutat. Res.
, vol.460
, pp. 165-181
-
-
Pearl, L.H.1
-
96
-
-
0023651289
-
A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine
-
T.C. Brown, and J. Jiricny A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine Cell 50 1987 945 950
-
(1987)
Cell
, vol.50
, pp. 945-950
-
-
Brown, T.C.1
Jiricny, J.2
-
97
-
-
0035233134
-
Thymine DNA glycosylase
-
U. Hardeland, M. Bentele, T. Lettieri, R. Steinacher, J. Jiricny, and P. Schar Thymine DNA glycosylase Prog. Nucl. Acid Res. Mol. Biol. 68 2001 235 253
-
(2001)
Prog. Nucl. Acid Res. Mol. Biol.
, vol.68
, pp. 235-253
-
-
Hardeland, U.1
Bentele, M.2
Lettieri, T.3
Steinacher, R.4
Jiricny, J.5
Schar, P.6
-
98
-
-
0029805081
-
A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase
-
P. Gallinari, and J. Jiricny A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase Nature 383 1996 735 738
-
(1996)
Nature
, vol.383
, pp. 735-738
-
-
Gallinari, P.1
Jiricny, J.2
-
99
-
-
0032506037
-
A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch
-
B. Hang, M. Medina, H. Fraenkel-Conrat, and B. Singer A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch Proc. Natl. Acad. Sci. U.S.A. 95 1998 13561 13566
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 13561-13566
-
-
Hang, B.1
Medina, M.2
Fraenkel-Conrat, H.3
Singer, B.4
-
100
-
-
0345296914
-
Crystal structure of a thwarted mismatch glycosylase DNA repair complex
-
T.E. Barrett, O.D. Scharer, R. Savva, T. Brown, J. Jiricny, G.L. Verdine, and L.H. Pearl Crystal structure of a thwarted mismatch glycosylase DNA repair complex EMBO J. 18 1999 6599 6609
-
(1999)
EMBO J.
, vol.18
, pp. 6599-6609
-
-
Barrett, T.E.1
Scharer, O.D.2
Savva, R.3
Brown, T.4
Jiricny, J.5
Verdine, G.L.6
Pearl, L.H.7
-
101
-
-
0033602148
-
Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors
-
K.A. Haushalter, M.W. Todd Stukenberg, M.W. Kirschner, and G.L. Verdine Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors Curr. Biol. 9 1999 174 185
-
(1999)
Curr. Biol.
, vol.9
, pp. 174-185
-
-
Haushalter, K.A.1
Todd Stukenberg, M.W.2
Kirschner, M.W.3
Verdine, G.L.4
-
102
-
-
0038185257
-
Mammalian 5-formyluracil-DNA glycosylase. 1. Identification and characterization of a novel activity that releases 5-formyluracil from DNA
-
M. Matsubara, A. Masaoka, T. Tanaka, T. Miyano, N. Kato, H. Terato, Y. Ohyama, S. Iwai, and H. Ide Mammalian 5-formyluracil-DNA glycosylase. 1. Identification and characterization of a novel activity that releases 5-formyluracil from DNA Biochemistry 42 2003 4993 5002
-
(2003)
Biochemistry
, vol.42
, pp. 4993-5002
-
-
Matsubara, M.1
Masaoka, A.2
Tanaka, T.3
Miyano, T.4
Kato, N.5
Terato, H.6
Ohyama, Y.7
Iwai, S.8
Ide, H.9
-
103
-
-
0035834708
-
Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1
-
R.J. Boorstein, A. Cummings Jr., D.R. Marenstein, M.K. Chan, Y. Ma, T.A. Neubert, S.M. Brown, and G.W. Teebor Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1 J. Biol. Chem. 276 2001 41991 41997
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41991-41997
-
-
Boorstein, R.J.1
Cummings Jr., A.2
Marenstein, D.R.3
Chan, M.K.4
Ma, Y.5
Neubert, T.A.6
Brown, S.M.7
Teebor, G.W.8
-
104
-
-
0141996214
-
Crystal structure of a family 4 uracil-DNA glycosylase from Thermus thermophilus HB8
-
J. Hoseki, A. Okamoto, R. Masui, T. Shibata, Y. Inoue, S. Yokoyama, and S. Kuramitsu Crystal structure of a family 4 uracil-DNA glycosylase from Thermus thermophilus HB8 J. Mol. Biol. 333 2003 515 526
-
(2003)
J. Mol. Biol.
, vol.333
, pp. 515-526
-
-
Hoseki, J.1
Okamoto, A.2
Masui, R.3
Shibata, T.4
Inoue, Y.5
Yokoyama, S.6
Kuramitsu, S.7
-
105
-
-
0033777253
-
Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): Fundamental role of the catalytic domain
-
F. Petronzelli, A. Riccio, G.D. Markham, S.H. Seeholzer, M. Genuardi, M. Karbowski, A.T. Yeung, Y. Matsumoto, and A. Bellacosa Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain J. Cell Physiol. 185 2000 473 480
-
(2000)
J. Cell Physiol.
, vol.185
, pp. 473-480
-
-
Petronzelli, F.1
Riccio, A.2
Markham, G.D.3
Seeholzer, S.H.4
Genuardi, M.5
Karbowski, M.6
Yeung, A.T.7
Matsumoto, Y.8
Bellacosa, A.9
-
106
-
-
0033486062
-
Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1
-
I. Ohki, N. Shimotake, N. Fujita, M. Nakao, and M. Shirakawa Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1 EMBO J. 18 1999 6653 6661
-
(1999)
EMBO J.
, vol.18
, pp. 6653-6661
-
-
Ohki, I.1
Shimotake, N.2
Fujita, N.3
Nakao, M.4
Shirakawa, M.5
-
107
-
-
0035906936
-
Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA
-
I. Ohki, N. Shimotake, N. Fujita, J. Jee, T. Ikegami, M. Nakao, and M. Shirakawa Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA Cell 105 2001 487 497
-
(2001)
Cell
, vol.105
, pp. 487-497
-
-
Ohki, I.1
Shimotake, N.2
Fujita, N.3
Jee, J.4
Ikegami, T.5
Nakao, M.6
Shirakawa, M.7
-
108
-
-
0033520515
-
The solution structure of the domain from MeCP2 that binds to methylated DNA
-
R.I. Wakefield, B.O. Smith, X. Nan, A. Free, A. Soteriou, D. Uhrin, A.P. Bird, and P.N. Barlow The solution structure of the domain from MeCP2 that binds to methylated DNA J. Mol. Biol. 291 1999 1055 1065
-
(1999)
J. Mol. Biol.
, vol.291
, pp. 1055-1065
-
-
Wakefield, R.I.1
Smith, B.O.2
Nan, X.3
Free, A.4
Soteriou, A.5
Uhrin, D.6
Bird, A.P.7
Barlow, P.N.8
-
109
-
-
0038475941
-
Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
-
P. Wu, C. Qiu, A. Sohail, X. Zhang, A.S. Bhagwat, and X. Cheng Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 J. Biol. Chem. 278 2003 5285 5291
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5285-5291
-
-
Wu, P.1
Qiu, C.2
Sohail, A.3
Zhang, X.4
Bhagwat, A.S.5
Cheng, X.6
-
110
-
-
0030587564
-
Human dUTP pyrophosphatase: Uracil recognition by a beta hairpin and active sites formed by three separate subunits
-
C.D. Mol, J.M. Harris, E.M. McIntosh, and J.A. Tainer Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits Structure 4 1996 1077 1092
-
(1996)
Structure
, vol.4
, pp. 1077-1092
-
-
Mol, C.D.1
Harris, J.M.2
McIntosh, E.M.3
Tainer, J.A.4
-
111
-
-
0033555756
-
Crystal structure of dUTPase from equine infectious anaemia virus; Active site metal binding in a substrate analogue complex
-
Z. Dauter, R. Persson, A.M. Rosengren, P.O. Nyman, K.S. Wilson, and E.S. Cedergren-Zeppezauer Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex J. Mol. Biol. 285 1999 655 673
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 655-673
-
-
Dauter, Z.1
Persson, R.2
Rosengren, A.M.3
Nyman, P.O.4
Wilson, K.S.5
Cedergren-Zeppezauer, E.S.6
-
112
-
-
0026595757
-
Crystal structure of a dUTPase
-
E.S. Cedergren-Zeppezauer, G. Larsson, P.O. Nyman, Z. Dauter, and K.S. Wilson Crystal structure of a dUTPase Nature 355 1992 740 743
-
(1992)
Nature
, vol.355
, pp. 740-743
-
-
Cedergren-Zeppezauer, E.S.1
Larsson, G.2
Nyman, P.O.3
Dauter, Z.4
Wilson, K.S.5
-
113
-
-
12644295057
-
Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus
-
G.S. Prasad, E.A. Stura, D.E. McRee, G.S. Laco, C. Hasselkus-Light, J.H. Elder, and C.D. Stout Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus Protein Sci. 5 1996 2429 2437
-
(1996)
Protein Sci.
, vol.5
, pp. 2429-2437
-
-
Prasad, G.S.1
Stura, E.A.2
McRee, D.E.3
Laco, G.S.4
Hasselkus-Light, C.5
Elder, J.H.6
Stout, C.D.7
-
114
-
-
0041665086
-
Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
-
J.L. Huffman, H. Li, R.H. White, and J.A. Tainer Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii J. Mol. Biol. 331 2003 885 896
-
(2003)
J. Mol. Biol.
, vol.331
, pp. 885-896
-
-
Huffman, J.L.1
Li, H.2
White, R.H.3
Tainer, J.A.4
-
115
-
-
17744410903
-
A bifunctional dCTP deaminase-dUTP nucleotidohydrolase from the hyperthermophilic archaeon Methanocaldococcus jannaschii
-
O. Bjornberg, J. Neuhard, and P.O. Nyman A bifunctional dCTP deaminase-dUTP nucleotidohydrolase from the hyperthermophilic archaeon Methanocaldococcus jannaschii J. Biol. Chem. 278 2003 20667 20672
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20667-20672
-
-
Bjornberg, O.1
Neuhard, J.2
Nyman, P.O.3
-
116
-
-
3342875968
-
Crystal structure of the Mycobacterium tuberculosis dUTPase: Insights into the catalytic mechanism
-
S. Chan, B. Segelke, T. Lekin, H. Krupka, U.S. Cho, M.Y. Kim, M. So, C.Y. Kim, C.M. Naranjo, Y.C. Rogers, M.S. Park, G.S. Waldo, I. Pashkov, D. Cascio, J.L. Perry, and M.R. Sawaya Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism J. Mol. Biol. 341 2004 503 517
-
(2004)
J. Mol. Biol.
, vol.341
, pp. 503-517
-
-
Chan, S.1
Segelke, B.2
Lekin, T.3
Krupka, H.4
Cho, U.S.5
Kim, M.Y.6
So, M.7
Kim, C.Y.8
Naranjo, C.M.9
Rogers, Y.C.10
Park, M.S.11
Waldo, G.S.12
Pashkov, I.13
Cascio, D.14
Perry, J.L.15
Sawaya, M.R.16
-
117
-
-
1642575114
-
The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold
-
M. Harkiolaki, E.J. Dodson, V. Bernier-Villamor, J.P. Turkenburg, D. Gonzalez-Pacanowska, and K.S. Wilson The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold Structure (Cambridge) 12 2004 41 53
-
(2004)
Structure (Cambridge)
, vol.12
, pp. 41-53
-
-
Harkiolaki, M.1
Dodson, E.J.2
Bernier-Villamor, V.3
Turkenburg, J.P.4
Gonzalez-Pacanowska, D.5
Wilson, K.S.6
-
118
-
-
4444321494
-
The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases
-
O.V. Moroz, M. Harkiolaki, M.Y. Galperin, A.A. Vagin, D. Gonzalez-Pacanowska, and K.S. Wilson The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases J. Mol. Biol. 342 2004 1583 1597
-
(2004)
J. Mol. Biol.
, vol.342
, pp. 1583-1597
-
-
Moroz, O.V.1
Harkiolaki, M.2
Galperin, M.Y.3
Vagin, A.A.4
Gonzalez-Pacanowska, D.5
Wilson, K.S.6
-
119
-
-
0027215935
-
Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli
-
S. Bjelland, M. Bjoras, and E. Seeberg Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli Nucl. Acids Res. 21 1993 2045 2049
-
(1993)
Nucl. Acids Res.
, vol.21
, pp. 2045-2049
-
-
Bjelland, S.1
Bjoras, M.2
Seeberg, E.3
-
120
-
-
0034733623
-
A novel 3-methyladenine DNA glycosylase from helicobacter pylori defines a new class within the endonuclease III family of base excision repair glycosylases
-
E.J. O'Rourke, C. Chevalier, S. Boiteux, A. Labigne, L. Ielpi, and J.P. Radicella A novel 3-methyladenine DNA glycosylase from helicobacter pylori defines a new class within the endonuclease III family of base excision repair glycosylases J. Biol. Chem. 275 2000 20077 20083
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20077-20083
-
-
O'Rourke, E.J.1
Chevalier, C.2
Boiteux, S.3
Labigne, A.4
Ielpi, L.5
Radicella, J.P.6
-
121
-
-
0034599723
-
Active and alkylated human AGT structures: A novel zinc site, inhibitor and extrahelical base binding
-
D.S. Daniels, C.D. Mol, A.S. Arvai, S. Kanugula, A.E. Pegg, and J.A. Tainer Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding EMBO J. 19 2000 1719 1730
-
(2000)
EMBO J.
, vol.19
, pp. 1719-1730
-
-
Daniels, D.S.1
Mol, C.D.2
Arvai, A.S.3
Kanugula, S.4
Pegg, A.E.5
Tainer, J.A.6
-
122
-
-
0033600847
-
Hyperthermostable protein structure maintained by intra and inter-helix ion-pairs in archaeal O6-methylguanine-DNA methyltransferase
-
H. Hashimoto, T. Inoue, M. Nishioka, S. Fujiwara, M. Takagi, T. Imanaka, and Y. Kai Hyperthermostable protein structure maintained by intra and inter-helix ion-pairs in archaeal O6-methylguanine-DNA methyltransferase J. Mol. Biol. 292 1999 707 716
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 707-716
-
-
Hashimoto, H.1
Inoue, T.2
Nishioka, M.3
Fujiwara, S.4
Takagi, M.5
Imanaka, T.6
Kai, Y.7
-
123
-
-
0035836501
-
Structural basis for the functional switch of the E. coli Ada protein
-
Y. Lin, V. Dotsch, T. Wintner, K. Peariso, L.C. Myers, J.E. Penner-Hahn, G.L. Verdine, and G. Wagner Structural basis for the functional switch of the E. coli Ada protein Biochemistry 40 2001 4261 4271
-
(2001)
Biochemistry
, vol.40
, pp. 4261-4271
-
-
Lin, Y.1
Dotsch, V.2
Wintner, T.3
Peariso, K.4
Myers, L.C.5
Penner-Hahn, J.E.6
Verdine, G.L.7
Wagner, G.8
-
124
-
-
0028354364
-
Crystal structure of a suicidal DNA repair protein: The Ada O6-methylguanine-DNA methyltransferase from E. coli
-
M.H. Moore, J.M. Gulbis, E.J. Dodson, B. Demple, and P.C. Moody Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli EMBO J. 13 1994 1495 1501
-
(1994)
EMBO J.
, vol.13
, pp. 1495-1501
-
-
Moore, M.H.1
Gulbis, J.M.2
Dodson, E.J.3
Demple, B.4
Moody, P.C.5
-
125
-
-
0037068446
-
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
-
S.C. Trewick, T.F. Henshaw, R.P. Hausinger, T. Lindahl, and B. Sedgwick Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage Nature 419 2002 174 178
-
(2002)
Nature
, vol.419
, pp. 174-178
-
-
Trewick, S.C.1
Henshaw, T.F.2
Hausinger, R.P.3
Lindahl, T.4
Sedgwick, B.5
-
126
-
-
0037068433
-
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
-
P.O. Falnes, R.F. Johansen, and E. Seeberg AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli Nature 419 2002 178 182
-
(2002)
Nature
, vol.419
, pp. 178-182
-
-
Falnes, P.O.1
Johansen, R.F.2
Seeberg, E.3
-
127
-
-
0035221419
-
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases
-
L. Aravind, and E.V. Koonin The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases Genome Biol. 2 2001 (RESEARCH0007)
-
(2001)
Genome Biol.
, vol.2
-
-
Aravind, L.1
Koonin, E.V.2
-
128
-
-
0037456369
-
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
-
P.A. Aas, M. Otterlei, P.O. Falnes, C.B. Vagbo, F. Skorpen, M. Akbari, O. Sundheim, M. Bjoras, G. Slupphaug, E. Seeberg, and H.E. Krokan Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA Nature 421 2003 859 863
-
(2003)
Nature
, vol.421
, pp. 859-863
-
-
Aas, P.A.1
Otterlei, M.2
Falnes, P.O.3
Vagbo, C.B.4
Skorpen, F.5
Akbari, M.6
Sundheim, O.7
Bjoras, M.8
Slupphaug, G.9
Seeberg, E.10
Krokan, H.E.11
-
129
-
-
0026491908
-
Crystal structure of TFIID TATA-box binding protein
-
D.B. Nikolov, S.H. Hu, J. Lin, A. Gasch, A. Hoffmann, M. Horikoshi, N.H. Chua, R.G. Roeder, and S.K. Burley Crystal structure of TFIID TATA-box binding protein Nature 360 1992 40 46
-
(1992)
Nature
, vol.360
, pp. 40-46
-
-
Nikolov, D.B.1
Hu, S.H.2
Lin, J.3
Gasch, A.4
Hoffmann, A.5
Horikoshi, M.6
Chua, N.H.7
Roeder, R.G.8
Burley, S.K.9
-
130
-
-
3042686671
-
The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site
-
P.J. O'Brien, and T. Ellenberger The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site J. Biol. Chem. 279 2004 26876 26884
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26876-26884
-
-
O'Brien, P.J.1
Ellenberger, T.2
-
131
-
-
0032518911
-
Release of normal bases from intact DNA by a native DNA repair enzyme
-
K.G. Berdal, R.F. Johansen, and E. Seeberg Release of normal bases from intact DNA by a native DNA repair enzyme EMBO J. 17 1998 363 367
-
(1998)
EMBO J.
, vol.17
, pp. 363-367
-
-
Berdal, K.G.1
Johansen, R.F.2
Seeberg, E.3
-
132
-
-
0034610336
-
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
-
A.Y. Lau, M.D. Wyatt, B.J. Glassner, L.D. Samson, and T. Ellenberger Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG Proc. Natl. Acad. Sci. U.S.A. 97 2000 13573 13578
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13573-13578
-
-
Lau, A.Y.1
Wyatt, M.D.2
Glassner, B.J.3
Samson, L.D.4
Ellenberger, T.5
-
133
-
-
0030595337
-
Structural classification of HTH DNA-binding domains and protein-DNA interaction modes
-
R. Wintjens, and M. Rooman Structural classification of HTH DNA-binding domains and protein-DNA interaction modes J. Mol. Biol. 262 1996 294 313
-
(1996)
J. Mol. Biol.
, vol.262
, pp. 294-313
-
-
Wintjens, R.1
Rooman, M.2
-
134
-
-
14844346741
-
A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O6-alkylguanine-DNA alkyltransferase and endonuclease V activities
-
S. Kanugula, G.T. Pauly, R.C. Moschel, and A.E. Pegg A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O6-alkylguanine-DNA alkyltransferase and endonuclease V activities Proc. Natl. Acad. Sci U.S.A. 2005
-
(2005)
Proc. Natl. Acad. Sci U.S.A.
-
-
Kanugula, S.1
Pauly, G.T.2
Moschel, R.C.3
Pegg, A.E.4
-
135
-
-
0742321956
-
Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair
-
B.R. Chapados, D.J. Hosfield, S. Han, J. Qiu, B. Yelent, B. Shen, and J.A. Tainer Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair Cell 116 2004 39 50
-
(2004)
Cell
, vol.116
, pp. 39-50
-
-
Chapados, B.R.1
Hosfield, D.J.2
Han, S.3
Qiu, J.4
Yelent, B.5
Shen, B.6
Tainer, J.A.7
-
136
-
-
0026544541
-
X-ray structure of T4 endonuclease V: An excision repair enzyme specific for a pyrimidine dimer
-
K. Morikawa, O. Matsumoto, M. Tsujimoto, K. Katayanagi, M. Ariyoshi, T. Doi, M. Ikehara, T. Inaoka, and E. Ohtsuka X-ray structure of T4 endonuclease V: an excision repair enzyme specific for a pyrimidine dimer Science 256 1992 523 526
-
(1992)
Science
, vol.256
, pp. 523-526
-
-
Morikawa, K.1
Matsumoto, O.2
Tsujimoto, M.3
Katayanagi, K.4
Ariyoshi, M.5
Doi, T.6
Ikehara, M.7
Inaoka, T.8
Ohtsuka, E.9
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