Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations

Journal of Biological Chemistry

Volumn 282, Issue 12, 2007, Pages 9182-9184

  Radom, Christopher T ^a   Banerjee, Anirban ^a,d   Verdine, Gregory L ^a,b,c  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC RESIDUES; DNA GLYCOSYLASES; HIGH RESOLUTION STRUCTURAL ANALYSIS; LESION RECOGNITION;

CATALYSIS; CATALYST ACTIVITY; DNA; ENZYME ACTIVITY; PROTEINS; SUBSTITUTION REACTIONS;

ENZYME KINETICS;

ALANINE; HUMAN 8 OXOGUANINE DNA GLYCOSYLASE; PHOSPHATE; PROTEIN; UNCLASSIFIED DRUG; CROSS LINKING REAGENT; DNA GLYCOSYLTRANSFERASE; OXOGUANINE GLYCOSYLASE 1, HUMAN;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME STRUCTURE; MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; STRESS; STRUCTURE ANALYSIS; BINDING SITE; CATALYSIS; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; HUMAN; MOLECULAR CLONING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ALANINE; AMINO ACID MOTIFS; BINDING SITES; CATALYSIS; CLONING, MOLECULAR; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; DNA GLYCOSYLASES; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 34247862129     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608989200     Document Type: Article

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