Mutation versus repair: NEILl removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts

Biochemistry

Volumn 49, Issue 8, 2010, Pages 1658-1666

  Zhao, Xiaobei ^a   Krishnamurthy, Nirmala ^a   Burrows, Cynthia J ^a   David, Sheila S ^b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUBBLE STRUCTURES; DNA GLYCOSYLASE; DNA LIGASES; DUPLEX DNA; FRAME-SHIFT MUTATION; GLYCOSYLASE; HYDANTOINS; POLYNUCLEOTIDES; POTENTIAL MECHANISM; SINGLE-STRANDED DNA; SPIROIMINODIHYDANTOIN; STRAND BREAKS; TEMPLATE STRAND;

DNA; GENES; NUCLEIC ACIDS; TRANSCRIPTION;

SUBSTRATES;

DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; HYDANTOIN; NEIL1 ENZYME; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYNUCLEOTIDE 5' HYDROXYL KINASE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; DNA REPAIR; DNA STRUCTURE; ENZYME ACTIVITY; FRAMESHIFT MUTATION; GENE REPLICATION; GENE SEQUENCE; PRIORITY JOURNAL; PROTEIN STRUCTURE;

BASE SEQUENCE; DNA; DNA GLYCOSYLASES; DNA REPAIR; DNA REPLICATION; DNA, SINGLE-STRANDED; GUANIDINES; GUANOSINE; HUMANS; HYDANTOINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; SPIRO COMPOUNDS;

EID: 77749252749     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901852q     Document Type: Article

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