Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

Nature

Volumn 471, Issue 7337, 2011, Pages 245-249

  Simsek, Deniz ^a,b   Furda, Amy ^c   Gao, Yankun ^d   Artus, Jérôme ^a   Brunet, Erika ^a,e,f,g   Hadjantonakis, Anna Katerina ^a,b   Van Houten, Bennett ^c   Shuman, Stewart ^a,b   McKinnon, Peter J ^d   Jasin, Maria ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^f CNRS   (France)

^g INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CRE RECOMBINASE; DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE III; UNCLASSIFIED DRUG; XRCC1 PROTEIN; ZINC FINGER PROTEIN;

ALLELE; CELL ORGANELLE; COLIFORM BACTERIUM; EMBRYONIC DEVELOPMENT; ENZYME ACTIVITY; MITOCHONDRIAL DNA; PROTEIN; RECOMBINATION; RODENT;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CATALYSIS; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EMBRYONIC STEM CELL; MAMMAL CELL; MITOCHONDRION; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL;

ANIMALS; BIOCATALYSIS; CELL SURVIVAL; DNA DAMAGE; DNA LIGASES; DNA REPAIR; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; GENES, ESSENTIAL; GENETIC COMPLEMENTATION TEST; HUMANS; MICE; MITOCHONDRIA; PROTEIN STRUCTURE, TERTIARY; SISTER CHROMATID EXCHANGE;

CHLORELLA VIRUS; ESCHERICHIA COLI; EUKARYOTA; LIGA; MAMMALIA; MUS; VERTEBRATA;

EID: 79952426030     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09794     Document Type: Article

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