-
1
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl, T. Instability and decay of the primary structure of DNA. Nature 362, 709-715 (1993).
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
2
-
-
85015066476
-
DNA damage and repair
-
Friedberg, E. C. DNA damage and repair. Nature 421, 436-440 (2003).
-
(2003)
Nature
, vol.421
, pp. 436-440
-
-
Friedberg, E.C.1
-
3
-
-
0037152628
-
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers
-
Pfeifer, G. P. et al. Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 21, 7435-7451 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 7435-7451
-
-
Pfeifer, G.P.1
-
4
-
-
4544304799
-
Inroads into base excision repair II. The discovery of the DNA glycosylases
-
Friedberg, E. C. Inroads into base excision repair II. The discovery of the DNA glycosylases. DNA Repair (Amst.) 3, 1531-1536 (2004).
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 1531-1536
-
-
Friedberg, E.C.1
-
5
-
-
0001473891
-
Chemistry of glycosylases and endonucleases involved in base-excision repair
-
David, S. S. & Williams, S. D. Chemistry of glycosylases and endonucleases involved in base-excision repair. Chem. Rev. 98, 1221-1261 (1998).
-
(1998)
Chem. Rev
, vol.98
, pp. 1221-1261
-
-
David, S.S.1
Williams, S.D.2
-
7
-
-
10944251591
-
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
-
Barnes, D. E. & Lindahl, T. Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu. Rev. Genet. 38, 445-476 (2004).
-
(2004)
Annu. Rev. Genet
, vol.38
, pp. 445-476
-
-
Barnes, D.E.1
Lindahl, T.2
-
8
-
-
33646859065
-
Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA
-
Sung, J.-S. & Demple, B. Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA. FEBS J. 273, 1620-1629 (2006).
-
(2006)
FEBS J
, vol.273
, pp. 1620-1629
-
-
Sung, J.-S.1
Demple, B.2
-
10
-
-
33646080824
-
Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products
-
Neeley, W. L. & Essigmann, J. M. Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products. Chem. Res. Toxicol. 19, 491-505 (2006).
-
(2006)
Chem. Res. Toxicol
, vol.19
, pp. 491-505
-
-
Neeley, W.L.1
Essigmann, J.M.2
-
11
-
-
4243545125
-
Oxidative nucleobase modifications leading to strand scission
-
Burrows, C. M. & Muller, J. Oxidative nucleobase modifications leading to strand scission. Chem. Rev. 98, 1109-1152 (1998).
-
(1998)
Chem. Rev
, vol.98
, pp. 1109-1152
-
-
Burrows, C.M.1
Muller, J.2
-
12
-
-
0025981359
-
Insertion of specific bases during DNA synthesis past the oxidation damaged base 8-oxodG
-
Shibutani, S., Takeshita, M. & Grollman, A. P. Insertion of specific bases during DNA synthesis past the oxidation damaged base 8-oxodG. Nature 349, 431-434 (1991).
-
(1991)
Nature
, vol.349
, pp. 431-434
-
-
Shibutani, S.1
Takeshita, M.2
Grollman, A.P.3
-
13
-
-
4544273926
-
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase
-
Hsu, G. W., Ober, M., Carell, T. & Beese, L. S. Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature 431, 217-221 (2004).
-
(2004)
Nature
, vol.431
, pp. 217-221
-
-
Hsu, G.W.1
Ober, M.2
Carell, T.3
Beese, L.S.4
-
14
-
-
0026701365
-
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
-
Michaels, M. L. & Miller, J. H. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J. Bacteriol. 174, 6321-6325 (1992).
-
(1992)
J. Bacteriol
, vol.174
, pp. 6321-6325
-
-
Michaels, M.L.1
Miller, J.H.2
-
15
-
-
0037227566
-
Structure of DNA polymerase β with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential
-
Krahn, J. M., Beard, W. A., Miller, H., Grollman, A. P. & Wilson, S. H. Structure of DNA polymerase β with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential. Structure 11, 121-127 (2003).
-
(2003)
Structure
, vol.11
, pp. 121-127
-
-
Krahn, J.M.1
Beard, W.A.2
Miller, H.3
Grollman, A.P.4
Wilson, S.H.5
-
16
-
-
11244327638
-
Establishing the background level of base oxidation in human lymphocyte DNA: Results on an interlaboratory validation study
-
Gedik, C. M. & Collins, A. Establishing the background level of base oxidation in human lymphocyte DNA: results on an interlaboratory validation study. FASEB J. 19, 82-84 (2005).
-
(2005)
FASEB J
, vol.19
, pp. 82-84
-
-
Gedik, C.M.1
Collins, A.2
-
17
-
-
0034734380
-
Lessons learned from structural results on uracil-DNA glycosylase
-
Parikh, S. S., Putnam, C. D. & Tainer, J. A. Lessons learned from structural results on uracil-DNA glycosylase. Mutat. Res. 460, 183-199 (2000).
-
(2000)
Mutat. Res
, vol.460
, pp. 183-199
-
-
Parikh, S.S.1
Putnam, C.D.2
Tainer, J.A.3
-
18
-
-
4143149415
-
Site-specific DNA damage recognition by enzyme-induced base flipping
-
Stivers, J. T. Site-specific DNA damage recognition by enzyme-induced base flipping. Prog. Nucleic Acid Res. Mol. Biol. 77, 37-65 (2004).
-
(2004)
Prog. Nucleic Acid Res. Mol. Biol
, vol.77
, pp. 37-65
-
-
Stivers, J.T.1
-
19
-
-
1342324026
-
DNA glycosylase recognition and catalysis
-
Fromme, J. C., Banerjee, A. & Verdine, G. L. DNA glycosylase recognition and catalysis. Curr. Opin. Struct. Biol. 14, 43-49 (2004).
-
(2004)
Curr. Opin. Struct. Biol
, vol.14
, pp. 43-49
-
-
Fromme, J.C.1
Banerjee, A.2
Verdine, G.L.3
-
20
-
-
24044460415
-
DNA base damage recognition and removal: New twists and grooves
-
Huffman, J. L., Sundheim, O. & Tainer, J. A. DNA base damage recognition and removal: new twists and grooves. Mutat. Res. 577, 55-76 (2005).
-
(2005)
Mutat. Res
, vol.577
, pp. 55-76
-
-
Huffman, J.L.1
Sundheim, O.2
Tainer, J.A.3
-
21
-
-
33847673237
-
The intricate structural chemistry of base excision repair machinery: Implications for DNA damage recognition, removal and repair
-
Hitomi, K., Iwai, S. & Tainer, J. A. The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal and repair. DNA Repair (Amst.) 6, 410-428 (2007).
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 410-428
-
-
Hitomi, K.1
Iwai, S.2
Tainer, J.A.3
-
22
-
-
0034708226
-
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
-
Bruner, S. D., Norman, D. P. & Verdine, G. L. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature 403, 859-866 (2000).
-
(2000)
Nature
, vol.403
, pp. 859-866
-
-
Bruner, S.D.1
Norman, D.P.2
Verdine, G.L.3
-
23
-
-
15844379169
-
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA
-
Banerjee, A., Yang, W., Karplus, M. & Verdine, G. L. Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature 434, 612-618 (2005).
-
(2005)
Nature
, vol.434
, pp. 612-618
-
-
Banerjee, A.1
Yang, W.2
Karplus, M.3
Verdine, G.L.4
-
24
-
-
34247862129
-
Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations
-
Radom, C. T., Banerjee, A. & Verdine, G. L. Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J. Biol. Chem. 282, 9182-9194 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 9182-9194
-
-
Radom, C.T.1
Banerjee, A.2
Verdine, G.L.3
-
25
-
-
33750079253
-
A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex
-
Banerjee, A. & Verdine, G. L. A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex. Proc. Natl Acad. Sci. USA 103, 15020-15025 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 15020-15025
-
-
Banerjee, A.1
Verdine, G.L.2
-
26
-
-
33644511436
-
Structure of a DNA glycosylase searching for DNA lesions
-
Banerjee, A., Santos, W. L. & Verdine, G. L. Structure of a DNA glycosylase searching for DNA lesions. Science 311, 1153-1157 (2006).
-
(2006)
Science
, vol.311
, pp. 1153-1157
-
-
Banerjee, A.1
Santos, W.L.2
Verdine, G.L.3
-
27
-
-
0346435086
-
DNA lesion recognition by the bacterial repair enzyme MutM
-
Fromme, J. C. & Verdine, G. L. DNA lesion recognition by the bacterial repair enzyme MutM. J. Biol. Chem. 278, 51543-51548 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 51543-51548
-
-
Fromme, J.C.1
Verdine, G.L.2
-
28
-
-
33645807371
-
A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA
-
Blainey, P. C., van Oijen, A. M., Banerjee, A., Verdine, G. L. & Xie, X. S. A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. Proc. Natl Acad. Sci. USA 103, 5752-5757 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 5752-5757
-
-
Blainey, P.C.1
van Oijen, A.M.2
Banerjee, A.3
Verdine, G.L.4
Xie, X.S.5
-
29
-
-
10644278833
-
Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase
-
Jiang, Y. L. et al. Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase. Biochemistry 43, 15429-15438 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 15429-15438
-
-
Jiang, Y.L.1
-
30
-
-
0033580647
-
The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity of 8-oxoguanine-adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase
-
Noll, D. M., Gogos, A., Granek, J. A. & Clarke, N. D. The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity of 8-oxoguanine-adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase. Biochemistry 38, 6374-6379 (1999).
-
(1999)
Biochemistry
, vol.38
, pp. 6374-6379
-
-
Noll, D.M.1
Gogos, A.2
Granek, J.A.3
Clarke, N.D.4
-
31
-
-
0035863770
-
Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain
-
Chmiel, N. H., Golinelli, M.-P., Francis, A. W. & David, S. S. Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain. Nucleic Acids Res. 29, 553-564 (2001).
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 553-564
-
-
Chmiel, N.H.1
Golinelli, M.-P.2
Francis, A.W.3
David, S.S.4
-
32
-
-
1342304229
-
Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
-
Fromme, J. C., Banerjee, A., Huang, S. J. & Verdine, G. L. Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature 427, 652-656 (2004).
-
(2004)
Nature
, vol.427
, pp. 652-656
-
-
Fromme, J.C.1
Banerjee, A.2
Huang, S.J.3
Verdine, G.L.4
-
33
-
-
0042527365
-
Repair of DNA containing FapydG and its C-nucleoside analogue by formamidopyrimidine DNA glycosylase and MutY
-
Wiederholdt, C. J., Delaney, M. O., Pope, M. A., David, S. S. & Greenberg, M. M. Repair of DNA containing FapydG and its C-nucleoside analogue by formamidopyrimidine DNA glycosylase and MutY. Biochemistry 42, 9755-9760 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 9755-9760
-
-
Wiederholdt, C.J.1
Delaney, M.O.2
Pope, M.A.3
David, S.S.4
Greenberg, M.M.5
-
34
-
-
0037036363
-
Flipping duplex DNA inside out: A double base-flipping reaction mechanism by Escherichia coli MutY adenine glycosylase
-
Bernards, A. S., Miller, J. K., Bao, K. K. & Wong, I. Flipping duplex DNA inside out: a double base-flipping reaction mechanism by Escherichia coli MutY adenine glycosylase. J. Biol. Chem. 277, 20960-20964 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 20960-20964
-
-
Bernards, A.S.1
Miller, J.K.2
Bao, K.K.3
Wong, I.4
-
35
-
-
0036478899
-
Inherited variants of MYH associated with somatic G:C to T:A mutations in colorectal tumors
-
Al-Tassan, N. et al. Inherited variants of MYH associated with somatic G:C to T:A mutations in colorectal tumors. Nature Genet. 30, 227-232 (2002).
-
(2002)
Nature Genet
, vol.30
, pp. 227-232
-
-
Al-Tassan, N.1
-
36
-
-
0035057699
-
The ABC of APC
-
Fearnhead, N. S., Britton, M. P. & Bodmer, W. F. The ABC of APC. Hum. Mol. Genet. 10, 721-733 (2001).
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 721-733
-
-
Fearnhead, N.S.1
Britton, M.P.2
Bodmer, W.F.3
-
37
-
-
0037459233
-
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: Complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E. coli enzymes
-
Chmiel, N. H., Livingston, A. L. & David, S. S. Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E. coli enzymes. J. Mol. Biol. 327, 431-443 (2003).
-
(2003)
J. Mol. Biol
, vol.327
, pp. 431-443
-
-
Chmiel, N.H.1
Livingston, A.L.2
David, S.S.3
-
38
-
-
23844445506
-
MutYH (MYH) and colorectal cancer
-
Sampson, J. R., Jones, S., Dolwani, S. & Cheadle, J. P. MutYH (MYH) and colorectal cancer. Biochem. Soc. Trans. 33, 679-683 (2005).
-
(2005)
Biochem. Soc. Trans
, vol.33
, pp. 679-683
-
-
Sampson, J.R.1
Jones, S.2
Dolwani, S.3
Cheadle, J.P.4
-
39
-
-
33847333956
-
MUTYH-associated polyposis - from defect in base excision repair to clinical genetic testing
-
Cheadle, J. P. & Sampson, J. R. MUTYH-associated polyposis - from defect in base excision repair to clinical genetic testing. DNA Repair (Amst.) 6, 274-279 (2007).
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 274-279
-
-
Cheadle, J.P.1
Sampson, J.R.2
-
40
-
-
27444434257
-
Insight into the roles of tyrosine 82 and glycine 253 in the Escherichia coli adenine glycosylase MutY
-
Livingston, A. L., Kundu, S., Henderson-Pozzi, M., Anderson, D. W. & David, S. S. Insight into the roles of tyrosine 82 and glycine 253 in the Escherichia coli adenine glycosylase MutY. Biochemistry 44, 14179-14190 (2005).
-
(2005)
Biochemistry
, vol.44
, pp. 14179-14190
-
-
Livingston, A.L.1
Kundu, S.2
Henderson-Pozzi, M.3
Anderson, D.W.4
David, S.S.5
-
41
-
-
12344258702
-
Insight into the functional consequences of hMYH variants associated with colorectal cancer: Distinct differences in the adenine glycosylase activity and the response to AP endonuclease of Y150C and G365D murine MYH
-
Pope, M. A., Chmiel, N. H. & David, S. S. Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonuclease of Y150C and G365D murine MYH. DNA Repair (Amst.) 4, 315-325 (2005).
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 315-325
-
-
Pope, M.A.1
Chmiel, N.H.2
David, S.S.3
-
42
-
-
2942696205
-
MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain
-
Tominaga, Y. et al. MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. Nucleic Acids Res. 32, 3198-3211 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 3198-3211
-
-
Tominaga, Y.1
-
43
-
-
1242338775
-
Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer
-
Wooden, S. H., Bassett, H. M., Wood, T. G. & McCullough, A. K. Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer. Cancer Lett. 205, 89-95 (2004).
-
(2004)
Cancer Lett
, vol.205
, pp. 89-95
-
-
Wooden, S.H.1
Bassett, H.M.2
Wood, T.G.3
McCullough, A.K.4
-
44
-
-
0141532257
-
Mutator phenotype of MutYH-null mouse embryonic stem cells
-
Hirano, S. et al. Mutator phenotype of MutYH-null mouse embryonic stem cells. J. Biol. Chem. 278, 38121-38124 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 38121-38124
-
-
Hirano, S.1
-
45
-
-
10744220394
-
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway
-
Lipton, L. et al. Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway. Cancer Res. 63, 7595-7599 (2003).
-
(2003)
Cancer Res
, vol.63
, pp. 7595-7599
-
-
Lipton, L.1
-
46
-
-
2342520175
-
Deficiencies in mouse Myh and Ogg1 results in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
-
Xie, Y. et al. Deficiencies in mouse Myh and Ogg1 results in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res. 64, 3096-3102 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 3096-3102
-
-
Xie, Y.1
-
47
-
-
3042739635
-
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylase
-
Russo, M. T. et al. Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylase. Cancer Res. 64, 4411-4414 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 4411-4414
-
-
Russo, M.T.1
-
48
-
-
10844274799
-
Min/+) mice
-
Min/+) mice. Cancer Res. 64, 8876-8881 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 8876-8881
-
-
Sieber, O.M.1
-
49
-
-
0038501052
-
MYH polyposis: A new autosomal recessive form of familial adenomatous polyposis demanding reappraisal of genetic risk and family management
-
Sampson, J. R. et al. MYH polyposis: a new autosomal recessive form of familial adenomatous polyposis demanding reappraisal of genetic risk and family management. Lancet 362, 39-41 (2003).
-
(2003)
Lancet
, vol.362
, pp. 39-41
-
-
Sampson, J.R.1
-
50
-
-
4644335014
-
Colorectal cancer and inherited mutations in base-excision repair
-
Chow, E., Thirlwell, C., Macrae, F. & Lipton, L. Colorectal cancer and inherited mutations in base-excision repair. Lancet Oncol. 5, 600-606 (2004).
-
(2004)
Lancet Oncol
, vol.5
, pp. 600-606
-
-
Chow, E.1
Thirlwell, C.2
Macrae, F.3
Lipton, L.4
-
51
-
-
3543020359
-
The multiple colorectal adenoma phenotype and MYH, a excision repair gene
-
Lipton, L. & Tomlinson, I. The multiple colorectal adenoma phenotype and MYH, a excision repair gene. Clin. Gastroenterol. Hepatol. 2, 633-638 (2004).
-
(2004)
Clin. Gastroenterol. Hepatol
, vol.2
, pp. 633-638
-
-
Lipton, L.1
Tomlinson, I.2
-
52
-
-
33745920193
-
Association of MutYH and colorectal cancer
-
Tenesa, A. et al. Association of MutYH and colorectal cancer. Br. J. Cancer 95, 239-242 (2006).
-
(2006)
Br. J. Cancer
, vol.95
, pp. 239-242
-
-
Tenesa, A.1
-
53
-
-
33749011410
-
The genetics of FAP and FAP-like syndromes
-
Lipton, L. & Tomlinson, I. The genetics of FAP and FAP-like syndromes. Fam. Cancer 5, 221-226 (2006).
-
(2006)
Fam. Cancer
, vol.5
, pp. 221-226
-
-
Lipton, L.1
Tomlinson, I.2
-
54
-
-
20544452084
-
Germline susceptibility to colorectal cancer due to base-excision repair gene defects
-
Farrington, S. M. et al. Germline susceptibility to colorectal cancer due to base-excision repair gene defects. Am. J. Hum. Genet. 77, 112-119 (2005).
-
(2005)
Am. J. Hum. Genet
, vol.77
, pp. 112-119
-
-
Farrington, S.M.1
-
55
-
-
1542719919
-
Comprehensive analysis of the contribution of germline MYH variation of early-onset colorectal cancer
-
Fleischmann, C. et al. Comprehensive analysis of the contribution of germline MYH variation of early-onset colorectal cancer. Int. J. Cancer 109, 554-558 (2004).
-
(2004)
Int. J. Cancer
, vol.109
, pp. 554-558
-
-
Fleischmann, C.1
-
56
-
-
21344470459
-
Hereditary colorectal cancer syndromes
-
Strate, L. L. & Syngal, S. Hereditary colorectal cancer syndromes. Cancer Causes Control 16, 201-213 (2005).
-
(2005)
Cancer Causes Control
, vol.16
, pp. 201-213
-
-
Strate, L.L.1
Syngal, S.2
-
57
-
-
13844264431
-
Genetics of hereditary colorectal cancer
-
Jo, W. S. & Chung, D. C. Genetics of hereditary colorectal cancer. Semin. Oncol. 32, 11-23 (2005).
-
(2005)
Semin. Oncol
, vol.32
, pp. 11-23
-
-
Jo, W.S.1
Chung, D.C.2
-
58
-
-
33744973579
-
Cancer genetics: Colorectal cancer as a model
-
Bodmer, W. F. Cancer genetics: colorectal cancer as a model. J. Hum. Genet. 51, 391-396 (2006).
-
(2006)
J. Hum. Genet
, vol.51
, pp. 391-396
-
-
Bodmer, W.F.1
-
59
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K. W. & Vogelstein, B. Lessons from hereditary colorectal cancer. Cell 87, 159-170 (1996).
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
60
-
-
33645672858
-
Microsatellite instability in colorectal cancer
-
Soreide, K., Janssen, E. A. M., Soiland, H., Korner, H. & Baak, J. P. Microsatellite instability in colorectal cancer. Br. J. Surg. 93, 395-406 (2006).
-
(2006)
Br. J. Surg
, vol.93
, pp. 395-406
-
-
Soreide, K.1
Janssen, E.A.M.2
Soiland, H.3
Korner, H.4
Baak, J.P.5
-
61
-
-
33749067855
-
Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome
-
Lindor, N. M. et al. Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome. JAMA 296, 1507-1517 (2006).
-
(2006)
JAMA
, vol.296
, pp. 1507-1517
-
-
Lindor, N.M.1
-
62
-
-
2942538325
-
High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis
-
Venesio, T. et al. High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis. Gastroenterology 126, 1681-1685 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 1681-1685
-
-
Venesio, T.1
-
63
-
-
21244441064
-
Is prophylactic colectomy indicated in patients with MYH-associated polyposis?
-
Leite, J. S. et al. Is prophylactic colectomy indicated in patients with MYH-associated polyposis? Colorectal Dis. 7, 327-331 (2005).
-
(2005)
Colorectal Dis
, vol.7
, pp. 327-331
-
-
Leite, J.S.1
-
64
-
-
13744261252
-
Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis
-
Bai, H. et al. Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis. Nucleic Acids Res. 33, 597-604 (2005).
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 597-604
-
-
Bai, H.1
-
65
-
-
33947580840
-
Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis
-
Bai, H. et al. Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis. Cancer Lett. 250, 74-81 (2007).
-
(2007)
Cancer Lett
, vol.250
, pp. 74-81
-
-
Bai, H.1
-
66
-
-
33745065564
-
A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis
-
Alhopuro, P. et al. A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis. Hum. Mutat. 26, 393 (2005).
-
(2005)
Hum. Mutat
, vol.26
, pp. 393
-
-
Alhopuro, P.1
-
67
-
-
0033539610
-
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
-
Klunglund, A. et al. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl Acad. Sci. USA 96, 13300-13305 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 13300-13305
-
-
Klunglund, A.1
-
68
-
-
18744368449
-
A global DNA repair mechanism involving Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage
-
Osterod, M. et al. A global DNA repair mechanism involving Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. Oncogene 21, 8232-8239 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 8232-8239
-
-
Osterod, M.1
-
69
-
-
0034812540
-
Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice
-
Osterod, M. et al. Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice. Carcinogenesis 22, 1459-1463 (2001).
-
(2001)
Carcinogenesis
, vol.22
, pp. 1459-1463
-
-
Osterod, M.1
-
70
-
-
0037118577
-
Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product
-
Sunesen, M., Stevnsner, T., Brosh, R. M., Dianov, G. L. & Bohr, V. A. Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product. Oncogene 21, 3571-3578 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 3571-3578
-
-
Sunesen, M.1
Stevnsner, T.2
Brosh, R.M.3
Dianov, G.L.4
Bohr, V.A.5
-
71
-
-
84985053187
-
Mechanisms and products of photosensitized degradation of nucleic acids and related model compounds
-
Cadet, J., Decarroz, C., Wang, S. Y. & Midden, W. R. Mechanisms and products of photosensitized degradation of nucleic acids and related model compounds. Isr. J. Chem. 1983, 420-429 (1983).
-
(1983)
Isr. J. Chem
, vol.1983
, pp. 420-429
-
-
Cadet, J.1
Decarroz, C.2
Wang, S.Y.3
Midden, W.R.4
-
72
-
-
0028927763
-
Reaction of singlet oxygen with 2′-deoxyguanosine and DNA. Isolation and characterization of the main oxidation products
-
Ravanat, J. L. & Cadet, J. Reaction of singlet oxygen with 2′-deoxyguanosine and DNA. Isolation and characterization of the main oxidation products. Chem. Res. Toxicol. 8, 379-388 (1995).
-
(1995)
Chem. Res. Toxicol
, vol.8
, pp. 379-388
-
-
Ravanat, J.L.1
Cadet, J.2
-
73
-
-
0001014503
-
Phthalocyanine and naphthalocyanine photosensitized oxidation of 2′-deoxyguanosine: Distinct type I and type II products
-
Ravanat, J. L., Berger, M., Bernard, F., Langlois, R. & Ouellet, R. Phthalocyanine and naphthalocyanine photosensitized oxidation of 2′-deoxyguanosine: distinct type I and type II products. Photochem. Photobiol. 55, 809-814 (1992).
-
(1992)
Photochem. Photobiol
, vol.55
, pp. 809-814
-
-
Ravanat, J.L.1
Berger, M.2
Bernard, F.3
Langlois, R.4
Ouellet, R.5
-
74
-
-
0034624588
-
Characterization of spiroiminodihydantoin as a product of one-electron oxidation of 8-oxo-7,8-dihydroguanosine
-
Luo, W., Muller, J. G., Rachlin, E. M. & Burrows, C. J. Characterization of spiroiminodihydantoin as a product of one-electron oxidation of 8-oxo-7,8-dihydroguanosine. Org. Lett. 2, 613-616 (2000).
-
(2000)
Org. Lett
, vol.2
, pp. 613-616
-
-
Luo, W.1
Muller, J.G.2
Rachlin, E.M.3
Burrows, C.J.4
-
75
-
-
0035810395
-
Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue
-
Niles, J. C., Wishnok, J. S. & Tannenbaum, S. R. Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue. Org. Lett. 3, 963-966 (2001).
-
(2001)
Org. Lett
, vol.3
, pp. 963-966
-
-
Niles, J.C.1
Wishnok, J.S.2
Tannenbaum, S.R.3
-
76
-
-
0037149068
-
Spiroiminodihydantoin is a major product in the photooxidation of 2′-deoxyguanosine by the triplet states and oxyl radicals generated from hydroxyacetophenone photolysis and dioxetane thermolysis
-
Adam, W. et al. Spiroiminodihydantoin is a major product in the photooxidation of 2′-deoxyguanosine by the triplet states and oxyl radicals generated from hydroxyacetophenone photolysis and dioxetane thermolysis. Org. Lett. 4, 537-540 (2002).
-
(2002)
Org. Lett
, vol.4
, pp. 537-540
-
-
Adam, W.1
-
77
-
-
0036802909
-
Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanosine oxidation by transition metals
-
Burrows, C. J. et al. Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanosine oxidation by transition metals. Environ. Health Perspect. 110, 713-717 (2002).
-
(2002)
Environ. Health Perspect
, vol.110
, pp. 713-717
-
-
Burrows, C.J.1
-
78
-
-
0034932109
-
Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model
-
Luo, W., Muller, J. G., Rachlin, E. M. & Burrows, C. J. Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model. Chem. Res. Toxicol. 14, 927-938 (2001).
-
(2001)
Chem. Res. Toxicol
, vol.14
, pp. 927-938
-
-
Luo, W.1
Muller, J.G.2
Rachlin, E.M.3
Burrows, C.J.4
-
79
-
-
0037168491
-
In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment)
-
Kornyushyna, O., Berges, A. M., Muller, J. G. & Burrows, C. J. In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment). Biochemistry 41, 15304-15314 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 15304-15314
-
-
Kornyushyna, O.1
Berges, A.M.2
Muller, J.G.3
Burrows, C.J.4
-
80
-
-
0242592066
-
Effect of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts
-
Kornyushyna, O. & Burrows, C. J. Effect of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts. Biochemistry 42, 13008-13018 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 13008-13018
-
-
Kornyushyna, O.1
Burrows, C.J.2
-
81
-
-
0041571565
-
The hydantoin lesions from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo
-
Henderson, P. T. et al. The hydantoin lesions from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo. Biochemistry 42, 9257-9262 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 9257-9262
-
-
Henderson, P.T.1
-
82
-
-
33846846509
-
The substrate specificity of MutY for hyperoxidized guanine lesions in vivo
-
Delaney, S., Neeley, W. L., Delaney, J. C. & Essigmann, J. M. The substrate specificity of MutY for hyperoxidized guanine lesions in vivo. Biochemistry, 46, 1448-1455 (2007).
-
(2007)
Biochemistry
, vol.46
, pp. 1448-1455
-
-
Delaney, S.1
Neeley, W.L.2
Delaney, J.C.3
Essigmann, J.M.4
-
83
-
-
0034610403
-
Removal of hydantoin products of 8-oxoguanine oxidation by the Escherichia coli DNA repair enzyme, Fpg
-
Leipold, M. D., Muller, J. G., Burrows, C. J. & David, S. S. Removal of hydantoin products of 8-oxoguanine oxidation by the Escherichia coli DNA repair enzyme, Fpg. Biochemistry 39, 14984-14992 (2000).
-
(2000)
Biochemistry
, vol.39
, pp. 14984-14992
-
-
Leipold, M.D.1
Muller, J.G.2
Burrows, C.J.3
David, S.S.4
-
84
-
-
0141790433
-
Recognition and removal of oxidized guanines in duplex DNA by the base excision repair enzymes hOGG1, yOGG1 and yOGG2
-
Leipold, M. D., Workman, H., Muller, J. G., Burrows, C. J. & David, S. S. Recognition and removal of oxidized guanines in duplex DNA by the base excision repair enzymes hOGG1, yOGG1 and yOGG2. Biochemistry 42, 11373-11381 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 11373-11381
-
-
Leipold, M.D.1
Workman, H.2
Muller, J.G.3
Burrows, C.J.4
David, S.S.5
-
85
-
-
0035339684
-
Repair of hydantoins, one electron oxidation product of 8-oxoguanine, by DNA glycosylases of Escherichia coli
-
Hazra, T. K. et al. Repair of hydantoins, one electron oxidation product of 8-oxoguanine, by DNA glycosylases of Escherichia coli. Nucleic Acids Res. 29, 1967-1974 (2001).
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1967-1974
-
-
Hazra, T.K.1
-
86
-
-
0037435405
-
The enigma of endonuclease VIII
-
Wallace, S. S., Bandaru, V., Kathe, S. D. & Bond, J. P. The enigma of endonuclease VIII. DNA Repair (Amst.) 2, 441-453 (2003).
-
(2003)
DNA Repair (Amst.)
, vol.2
, pp. 441-453
-
-
Wallace, S.S.1
Bandaru, V.2
Kathe, S.D.3
Bond, J.P.4
-
87
-
-
25444521980
-
Nei-deficient Escherichia coli are sensitive to chromate and accumulate the oxidized guanine lesion spiroiminodihydantoin
-
Hailer, M. K., Slade, P. G., Martin, B. D. & Sugden, K. D. Nei-deficient Escherichia coli are sensitive to chromate and accumulate the oxidized guanine lesion spiroiminodihydantoin. Chem. Res. Toxicol. 18, 1378-1383 (2005).
-
(2005)
Chem. Res. Toxicol
, vol.18
, pp. 1378-1383
-
-
Hailer, M.K.1
Slade, P.G.2
Martin, B.D.3
Sugden, K.D.4
-
88
-
-
0037125133
-
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII
-
Bandaru, V., Sunkara, S., Wallace, S. S. & Bond, J. P. A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII. DNA Repair (Amst.) 1, 517-529 (2002).
-
(2002)
DNA Repair (Amst.)
, vol.1
, pp. 517-529
-
-
Bandaru, V.1
Sunkara, S.2
Wallace, S.S.3
Bond, J.P.4
-
89
-
-
0037133684
-
Identification and characterization of a human DNA glycosylase for repair of modified oxidatively damaged DNA
-
Hazra, T. K. et al. Identification and characterization of a human DNA glycosylase for repair of modified oxidatively damaged DNA. Proc. Natl Acad. Sci. USA 99, 3523-3528 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 3523-3528
-
-
Hazra, T.K.1
-
90
-
-
0037162995
-
Identification of a novel human DNA glycosylase for repair of cytosinederived lesions
-
Hazra, T. K. et al. Identification of a novel human DNA glycosylase for repair of cytosinederived lesions. J. Biol. Chem. 277, 30417-30420 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 30417-30420
-
-
Hazra, T.K.1
-
91
-
-
0037112668
-
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: An alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA
-
Morland, I. et al. Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA. Nucleic Acids Res. 30, 4926-4936 (2002).
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4926-4936
-
-
Morland, I.1
-
92
-
-
3142702720
-
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity
-
Doublie, S., Bandaru, V., Bond, J. P. & Wallace, S. S. The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc. Natl Acad. Sci. USA 101, 10284-10289 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10284-10289
-
-
Doublie, S.1
Bandaru, V.2
Bond, J.P.3
Wallace, S.S.4
-
93
-
-
0347379928
-
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
-
Dou, H., Mitra, S. & Hazra, T. K. Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. J. Biol. Chem. 278, 49679-49684 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 49679-49684
-
-
Dou, H.1
Mitra, S.2
Hazra, T.K.3
-
94
-
-
7944222565
-
Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the base excision repair glycosylases NEIL1 and NEIL2
-
Hailer, K. M., Slade, P. G., Martin, B. D., Rosenquist, T. A. & Sugden, K. D. Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the base excision repair glycosylases NEIL1 and NEIL2. DNA Repair (Amst.) 4, 41-50 (2005).
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 41-50
-
-
Hailer, K.M.1
Slade, P.G.2
Martin, B.D.3
Rosenquist, T.A.4
Sugden, K.D.5
-
95
-
-
27444431790
-
Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species
-
Das, A., Hazra, T. K., Boldogh, I., Mitra, S. & Bhakat, K. K. Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species. J. Biol. Chem. 280, 35272-35280 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 35272-35280
-
-
Das, A.1
Hazra, T.K.2
Boldogh, I.3
Mitra, S.4
Bhakat, K.K.5
-
96
-
-
0037435402
-
The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death
-
Rosenquist, T. A. et al. The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death. DNA Repair (Amst.) 2, 581-591 (2003).
-
(2003)
DNA Repair (Amst.)
, vol.2
, pp. 581-591
-
-
Rosenquist, T.A.1
-
97
-
-
10344242928
-
Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer
-
Shinmura, K. et al. Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer. Carcinogenesis 25, 2311-2317 (2004).
-
(2004)
Carcinogenesis
, vol.25
, pp. 2311-2317
-
-
Shinmura, K.1
-
98
-
-
32444434993
-
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase
-
Vartanian, V. et al. The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc. Natl Acad. Sci. USA 103, 1864-1869 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 1864-1869
-
-
Vartanian, V.1
-
99
-
-
0031763884
-
MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily
-
Guan, Y. et al. MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nature Struct. Biol. 5, 1058-1064 (1998).
-
(1998)
Nature Struct. Biol
, vol.5
, pp. 1058-1064
-
-
Guan, Y.1
-
100
-
-
16344377473
-
A role for iron-sulfur clusters in DNA repair
-
Lukianova, O. L. & David, S. S. A role for iron-sulfur clusters in DNA repair. Curr. Opin. Chem. Biol. 9, 145-151 (2005).
-
(2005)
Curr. Opin. Chem. Biol
, vol.9
, pp. 145-151
-
-
Lukianova, O.L.1
David, S.S.2
|