-
1
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl, T. (1993) Instability and decay of the primary structure of DNA. Nature 362, 709-715.
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
2
-
-
33847688859
-
Repair of alkylated DNA: Recent advances
-
Sedgwick, B., Bates, P. A., Paik, J., Jacobs, S. C. and Lindahl, T. (2007) Repair of alkylated DNA: recent advances. DNA Repair (Amst) 6, 429-442.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 429-442
-
-
Sedgwick, B.1
Bates, P.A.2
Paik, J.3
Jacobs, S.C.4
Lindahl, T.5
-
3
-
-
33847621554
-
Uracil in DNA - general mutagen, but normal intermediate in acquired immunity
-
Kavli, B., Otterlei, M., Slupphaug, G. and Krokan, H. E. (2007) Uracil in DNA - general mutagen, but normal intermediate in acquired immunity. DNA Repair (Amst) 6, 505-516.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 505-516
-
-
Kavli, B.1
Otterlei, M.2
Slupphaug, G.3
Krokan, H.E.4
-
4
-
-
0029842307
-
Reconstitution of DNA base excision-repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein
-
Kubota, Y., Nash, R. A., Klungland, A., Schar, P., Barnes, D. E. and Lindahl, T. (1996) Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. EMBO J. 15, 6662-6670.
-
(1996)
EMBO J
, vol.15
, pp. 6662-6670
-
-
Kubota, Y.1
Nash, R.A.2
Klungland, A.3
Schar, P.4
Barnes, D.E.5
Lindahl, T.6
-
5
-
-
0000476915
-
An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues
-
Lindahl, T. (1974) An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc. Natl. Acad. Sci. USA 71, 3649-3653.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 3649-3653
-
-
Lindahl, T.1
-
6
-
-
0018814768
-
Uracil-DNA glycosylase from Escherichia coli
-
Lindahl, T. (1980) Uracil-DNA glycosylase from Escherichia coli. Methods Enzymol. 65, 284-290.
-
(1980)
Methods Enzymol
, vol.65
, pp. 284-290
-
-
Lindahl, T.1
-
7
-
-
0016782046
-
N-Glycosidase activity in extracts of Bacillus subtilis and its inhibition after infection with bacteriophage PBS2
-
Friedberg, E. C., Ganesan, A. K. and Minton, K. (1975) N-Glycosidase activity in extracts of Bacillus subtilis and its inhibition after infection with bacteriophage PBS2. J. Virol. 16, 315-321.
-
(1975)
J. Virol
, vol.16
, pp. 315-321
-
-
Friedberg, E.C.1
Ganesan, A.K.2
Minton, K.3
-
8
-
-
0024414264
-
Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme
-
Olsen, L. C., Aasland, R., Wittwer, C. U., Krokan, H. E. and Helland, D. E. (1989) Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme. EMBO J. 8, 3121-3125.
-
(1989)
EMBO J
, vol.8
, pp. 3121-3125
-
-
Olsen, L.C.1
Aasland, R.2
Wittwer, C.U.3
Krokan, H.E.4
Helland, D.E.5
-
9
-
-
0017760103
-
Two enzymes are required from strand incision in repair of alkylated DNA
-
Laval, J. (1977) Two enzymes are required from strand incision in repair of alkylated DNA. Nature 269, 829-832.
-
(1977)
Nature
, vol.269
, pp. 829-832
-
-
Laval, J.1
-
10
-
-
0004370304
-
Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites
-
O'Connor, T. R. and Laval, J. (1989) Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites. Proc. Natl. Acad. Sci. USA 86, 5222-5226.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5222-5226
-
-
O'Connor, T.R.1
Laval, J.2
-
11
-
-
0025936119
-
Isolation of cDNA clones encoding a human apurinic/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects in E. coli xth (exonuclease III) mutants
-
Robson, C. N. and Hickson, I. D. (1991) Isolation of cDNA clones encoding a human apurinic/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects in E. coli xth (exonuclease III) mutants. Nucleic Acids Res. 19, 5519-5523.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 5519-5523
-
-
Robson, C.N.1
Hickson, I.D.2
-
12
-
-
0023433565
-
Formamidopyrimidine-DNA glycosylase of Escherichia coli: Cloning and sequencing of the fpg structural gene and overproduction of the protein
-
Boiteux, S., O'Connor, T. R. and Laval, J. (1987) Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein. EMBO J. 6, 3177-3183.
-
(1987)
EMBO J
, vol.6
, pp. 3177-3183
-
-
Boiteux, S.1
O'Connor, T.R.2
Laval, J.3
-
13
-
-
0029028964
-
Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair
-
Matsumoto, Y. and Kim, K. (1995) Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. Science 269, 699-702.
-
(1995)
Science
, vol.269
, pp. 699-702
-
-
Matsumoto, Y.1
Kim, K.2
-
14
-
-
0027179827
-
Short gap-filling synthesis by DNA polymerase beta is processive
-
Singhal, R. K. and Wilson, S. H. (1993) Short gap-filling synthesis by DNA polymerase beta is processive. J. Biol. Chem. 268, 15906-15911.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 15906-15911
-
-
Singhal, R.K.1
Wilson, S.H.2
-
15
-
-
0030030379
-
Requirement of mammalian DNA polymerase-beta in base-excision repair
-
Sobol, R. W., Horton, J. K., Kuhn, R., Gu, H., Singhal, R. K., Prasad, R., Rajewsky, K. and Wilson, S. H. (1996) Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature 379, 183-186.
-
(1996)
Nature
, vol.379
, pp. 183-186
-
-
Sobol, R.W.1
Horton, J.K.2
Kuhn, R.3
Gu, H.4
Singhal, R.K.5
Prasad, R.6
Rajewsky, K.7
Wilson, S.H.8
-
16
-
-
0029024927
-
Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination
-
Wei, Y. F., Robins, P., Carter, K., Caldecott, K., Pappin, D. J., Yu, G. L., Wang, R. P., Shell, B. K., Nash, R. A., Schar, P. et al. (1995) Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol. Cell Biol. 15, 3206-3216.
-
(1995)
Mol. Cell Biol
, vol.15
, pp. 3206-3216
-
-
Wei, Y.F.1
Robins, P.2
Carter, K.3
Caldecott, K.4
Pappin, D.J.5
Yu, G.L.6
Wang, R.P.7
Shell, B.K.8
Nash, R.A.9
Schar, P.10
-
17
-
-
0029873178
-
Two pathways for base excision repair in mammalian cells
-
Frosina, G., Fortini, P., Rossi, O., Carrozzino, F., Raspaglio, G., Cox, L. S., Lane, D.P., Abbondandolo, A. and Dogliotti, E. (1996) Two pathways for base excision repair in mammalian cells. J. Biol. Chem. 271, 9573-9578.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 9573-9578
-
-
Frosina, G.1
Fortini, P.2
Rossi, O.3
Carrozzino, F.4
Raspaglio, G.5
Cox, L.S.6
Lane, D.P.7
Abbondandolo, A.8
Dogliotti, E.9
-
18
-
-
0032502675
-
Involvement of flap endonuclease 1 in base excision DNA repair
-
Kim, K., Biade, S. and Matsumoto, Y. (1998) Involvement of flap endonuclease 1 in base excision DNA repair. J. Biol. Chem. 273, 8842-8848.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 8842-8848
-
-
Kim, K.1
Biade, S.2
Matsumoto, Y.3
-
19
-
-
0030957997
-
Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement for DNase IV (FEN1)
-
Klungland, A. and Lindahl, T. (1997) Second pathway for completion of human DNA base excision-repair: Reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 16, 3341-3348.
-
(1997)
EMBO J
, vol.16
, pp. 3341-3348
-
-
Klungland, A.1
Lindahl, T.2
-
20
-
-
2542457893
-
ATP-dependent selection between single nucleotide and long patch base excision repair
-
Petermann, E., Ziegler, M. and Oei, S. L. (2003) ATP-dependent selection between single nucleotide and long patch base excision repair. DNA Repair (Amst) 2, 1101-1114.
-
(2003)
DNA Repair (Amst)
, vol.2
, pp. 1101-1114
-
-
Petermann, E.1
Ziegler, M.2
Oei, S.L.3
-
21
-
-
0028157948
-
An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III
-
Caldecott, K. W., McKeown, C. K., Tucker, J. D., Ljungquist, S. and Thompson, L.H. (1994) An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III. Mol. Cell Biol. 14, 68-76.
-
(1994)
Mol. Cell Biol
, vol.14
, pp. 68-76
-
-
Caldecott, K.W.1
McKeown, C.K.2
Tucker, J.D.3
Ljungquist, S.4
Thompson, L.H.5
-
22
-
-
0027965229
-
Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: An alternative pathway of base excision DNA repair
-
Matsumoto, Y., Kim, K. and Bogenhagen, D. F. (1994) Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair. Mol. Cell Biol. 14, 6187-6197.
-
(1994)
Mol. Cell Biol
, vol.14
, pp. 6187-6197
-
-
Matsumoto, Y.1
Kim, K.2
Bogenhagen, D.F.3
-
23
-
-
0029885134
-
Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA
-
Wu, X. T., Li, J., Li, X. Y., Hsieh, C. L., Burgers, P. M. J. and Lieber, M. R. (1996) Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA. Nucleic Acids Res. 24, 2036-2043.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2036-2043
-
-
Wu, X.T.1
Li, J.2
Li, X.Y.3
Hsieh, C.L.4
Burgers, P.M.J.5
Lieber, M.R.6
-
24
-
-
34247599335
-
A unified view of base excision repair: Lesion-dependent protein complexes regulated by post-translational modification
-
Almeida, K. H. and Sobol, R. W. (2007) A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst) 6, 695-711.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 695-711
-
-
Almeida, K.H.1
Sobol, R.W.2
-
25
-
-
38049112778
-
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
-
Hegde, M. L., Hazra, T. K. and Mitra, S. (2008) Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res. 18, 27-47.
-
(2008)
Cell Res
, vol.18
, pp. 27-47
-
-
Hegde, M.L.1
Hazra, T.K.2
Mitra, S.3
-
26
-
-
33847699724
-
Oxidative damage to purines in DNA: Role of mammalian Ogg1
-
Klungland, A. and Bjelland, S. (2007) Oxidative damage to purines in DNA: role of mammalian Ogg1. DNA Repair (Amst) 6, 481-488.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 481-488
-
-
Klungland, A.1
Bjelland, S.2
-
27
-
-
0019198357
-
Mutagenic deamination of cytosine residues in DNA
-
Duncan, B. K. and Miller, J. H. (1980) Mutagenic deamination of cytosine residues in DNA. Nature 287, 560-561.
-
(1980)
Nature
, vol.287
, pp. 560-561
-
-
Duncan, B.K.1
Miller, J.H.2
-
28
-
-
0027316990
-
Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene
-
Slupphaug, G., Markussen, F. H., Olsen, L.C., Aasland, R., Aarsaether, N., Bakke, O., Krokan, H. E. and Helland, D. E. (1993) Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene. Nucleic Acids Res. 21, 2579-2584.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 2579-2584
-
-
Slupphaug, G.1
Markussen, F.H.2
Olsen, L.C.3
Aasland, R.4
Aarsaether, N.5
Bakke, O.6
Krokan, H.E.7
Helland, D.E.8
-
29
-
-
0028933306
-
Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase
-
Slupphaug, G., Eftedal, I., Kavli, B., Bharati, S., Helle, N. M., Haug, T., Levine, D. W. and Krokan, H. E. (1995) Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase. Biochemistry 34, 128-138.
-
(1995)
Biochemistry
, vol.34
, pp. 128-138
-
-
Slupphaug, G.1
Eftedal, I.2
Kavli, B.3
Bharati, S.4
Helle, N.M.5
Haug, T.6
Levine, D.W.7
Krokan, H.E.8
-
30
-
-
0029960063
-
Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage
-
Dizdaroglu, M., Karakaya, A., Jaruga, P., Slupphaug, G. and Krokan, H. E. (1996) Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage. Nucleic Acids Res. 24, 418-422.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 418-422
-
-
Dizdaroglu, M.1
Karakaya, A.2
Jaruga, P.3
Slupphaug, G.4
Krokan, H.E.5
-
31
-
-
0033602148
-
Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors
-
Haushalter, K. A., Todd Stukenberg, M. W., Kirschner, M. W. and Verdine, G. L. (1999) Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr. Biol. 9, 174-185.
-
(1999)
Curr. Biol
, vol.9
, pp. 174-185
-
-
Haushalter, K.A.1
Todd Stukenberg, M.W.2
Kirschner, M.W.3
Verdine, G.L.4
-
32
-
-
21844464297
-
C→T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
-
An, Q., Robins, P., Lindahl, T. and Barnes, D. E. (2005) C→T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases. EMBO J. 24, 2205-2213.
-
(2005)
EMBO J
, vol.24
, pp. 2205-2213
-
-
An, Q.1
Robins, P.2
Lindahl, T.3
Barnes, D.E.4
-
33
-
-
0029896229
-
Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine
-
van der Kemp, P. A., Thomas, D., Barbey, R., de, O. R. and Boiteux, S. (1996) Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine. Proc. Natl. Acad. Sci. USA 93, 5197-5202.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5197-5202
-
-
van der1
Kemp, P.A.2
Thomas, D.3
Barbey, R.4
de, O.R.5
Boiteux, S.6
-
34
-
-
0026701365
-
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
-
Michaels, M. L. and Miller, J. H. (1992) The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J. Bacteriol. 174, 6321-6325.
-
(1992)
J. Bacteriol
, vol.174
, pp. 6321-6325
-
-
Michaels, M.L.1
Miller, J.H.2
-
35
-
-
0030816108
-
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
-
Radicella, J. P., Dherin, C., Desmaze, C., Fox, M. S. and Boiteux, S. (1997) Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 94, 8010-8015.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8010-8015
-
-
Radicella, J.P.1
Dherin, C.2
Desmaze, C.3
Fox, M.S.4
Boiteux, S.5
-
36
-
-
0030759824
-
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
-
RoldanArjona, T., Wei, Y. F., Carter, K. C., Klungland, A., Anselmino, C., Wang, R. P., Augustus, M. and Lindahl, T. (1997) Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase. Proc. Natl. Acad. Sci. USA 94, 8016-8020.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8016-8020
-
-
RoldanArjona, T.1
Wei, Y.F.2
Carter, K.C.3
Klungland, A.4
Anselmino, C.5
Wang, R.P.6
Augustus, M.7
Lindahl, T.8
-
37
-
-
0030703177
-
Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
-
Bjoras, M., Luna, L., Johnsen, B., Hoff, E., Haug, T., Rognes, T. and Seeberg, E. (1997) Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J. 16, 6314-6322.
-
(1997)
EMBO J
, vol.16
, pp. 6314-6322
-
-
Bjoras, M.1
Luna, L.2
Johnsen, B.3
Hoff, E.4
Haug, T.5
Rognes, T.6
Seeberg, E.7
-
38
-
-
0033539610
-
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
-
Klungland, A., Rosewell, I., Hollenbach, S., Larsen, E., Daly, G., Epe, B., Seeberg, E., Lindahl, T. and Barnes, D. E. (1999) Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl. Acad. Sci. USA 96, 13300-13305.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13300-13305
-
-
Klungland, A.1
Rosewell, I.2
Hollenbach, S.3
Larsen, E.4
Daly, G.5
Epe, B.6
Seeberg, E.7
Lindahl, T.8
Barnes, D.E.9
-
39
-
-
0031926508
-
Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae
-
Girard, P. M., D'Ham, C., Cadet, J. and Boiteux, S. (1998) Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae. Carcinogenesis 19, 1299-1305.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1299-1305
-
-
Girard, P.M.1
D'Ham, C.2
Cadet, J.3
Boiteux, S.4
-
40
-
-
0038143225
-
Mammalian 8-oxoguanine DNA glycosylase 1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei
-
Jensen, A., Calvayrac, G., Karahalil, B., Bohr, V. A. and Stevnsner, T. (2003) Mammalian 8-oxoguanine DNA glycosylase 1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei. J. Biol. Chem. 278, 19541-19548.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 19541-19548
-
-
Jensen, A.1
Calvayrac, G.2
Karahalil, B.3
Bohr, V.A.4
Stevnsner, T.5
-
41
-
-
0025990209
-
Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16
-
Samson, L., Derfler, B., Boosalis, M. and Call, K. (1991) Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16. Proc. Natl. Acad. Sci. USA 88, 9127-9131.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9127-9131
-
-
Samson, L.1
Derfler, B.2
Boosalis, M.3
Call, K.4
-
42
-
-
0025630512
-
Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage
-
Chen, J., Derfler, B. and Samson, L. (1990) Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage. EMBO J. 9, 4569-4575.
-
(1990)
EMBO J
, vol.9
, pp. 4569-4575
-
-
Chen, J.1
Derfler, B.2
Samson, L.3
-
43
-
-
0025604278
-
Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene
-
Berdal, K. G., Bjoras, M., Bjelland, S. and Seeberg, E. (1990) Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene. EMBO J. 9, 4563-4568.
-
(1990)
EMBO J
, vol.9
, pp. 4563-4568
-
-
Berdal, K.G.1
Bjoras, M.2
Bjelland, S.3
Seeberg, E.4
-
44
-
-
0032518911
-
Release of normal bases from intact DNA by a native DNA repair enzyme
-
Berdal, K. G., Johansen, R. F. and Seeberg, E. (1998) Release of normal bases from intact DNA by a native DNA repair enzyme. EMBO J. 17, 363-367.
-
(1998)
EMBO J
, vol.17
, pp. 363-367
-
-
Berdal, K.G.1
Johansen, R.F.2
Seeberg, E.3
-
45
-
-
34247269030
-
Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA
-
Leiros, I., Nabong, M. P., Grosvik, K., Ringvoll, J., Haugland, G. T., Uldal, L., Reite, K., Olsbu, I. K., Knaevelsrud, I., Moe, E. et al. (2007) Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA. EMBO J. 26, 2206-2217.
-
(2007)
EMBO J
, vol.26
, pp. 2206-2217
-
-
Leiros, I.1
Nabong, M.P.2
Grosvik, K.3
Ringvoll, J.4
Haugland, G.T.5
Uldal, L.6
Reite, K.7
Olsbu, I.K.8
Knaevelsrud, I.9
Moe, E.10
-
46
-
-
24044460415
-
DNA base damage recognition and removal: New twists and grooves
-
Huffman, J. L., Sundheim, O. and Tainer, J. A. (2005) DNA base damage recognition and removal: new twists and grooves. Mutat. Res. 577, 55-76.
-
(2005)
Mutat. Res
, vol.577
, pp. 55-76
-
-
Huffman, J.L.1
Sundheim, O.2
Tainer, J.A.3
-
47
-
-
0034610336
-
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
-
Lau, A. Y., Wyatt, M. D., Glassner, B. J., Samson, L. D. and Ellenberger, T. (2000) Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc. Natl. Acad. Sci. USA 97, 13573-13578.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13573-13578
-
-
Lau, A.Y.1
Wyatt, M.D.2
Glassner, B.J.3
Samson, L.D.4
Ellenberger, T.5
-
48
-
-
0032538337
-
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: Mechanisms for nucleotide flipping and base excision
-
Lau, A. Y., Scharer, O. D., Samson, L., Verdine, G. L. and Ellenberger, T. (1998) Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell 95, 249-258.
-
(1998)
Cell
, vol.95
, pp. 249-258
-
-
Lau, A.Y.1
Scharer, O.D.2
Samson, L.3
Verdine, G.L.4
Ellenberger, T.5
-
49
-
-
0034599723
-
Active and alkylated human AGT structures: A novel zinc site, inhibitor and extrahelical base binding
-
Daniels, D. S., Mol, C. D., Arvai, A.S., Kanugula, S., Pegg, A. E. and Tainer, J. A. (2000) Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding. EMBO J. 19, 1719-1730.
-
(2000)
EMBO J
, vol.19
, pp. 1719-1730
-
-
Daniels, D.S.1
Mol, C.D.2
Arvai, A.S.3
Kanugula, S.4
Pegg, A.E.5
Tainer, J.A.6
-
50
-
-
33746622565
-
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage
-
Sundheim, O., Vagbo, C. B., Bjoras, M., Sousa, M. M., Talstad, V., Aas, P. A., Drablos, F., Krokan, H. E., Tainer, J. A. and Slupphaug, G. (2006) Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. EMBO J. 25, 3389-3397.
-
(2006)
EMBO J
, vol.25
, pp. 3389-3397
-
-
Sundheim, O.1
Vagbo, C.B.2
Bjoras, M.3
Sousa, M.M.4
Talstad, V.5
Aas, P.A.6
Drablos, F.7
Krokan, H.E.8
Tainer, J.A.9
Slupphaug, G.10
-
51
-
-
0034708226
-
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
-
Bruner, S. D., Norman, D. P. and Verdine, G. L. (2000) Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature 403, 859-866.
-
(2000)
Nature
, vol.403
, pp. 859-866
-
-
Bruner, S.D.1
Norman, D.P.2
Verdine, G.L.3
-
52
-
-
3142702720
-
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity
-
Doublie, S., Bandaru, V., Bond, J. P. and Wallace, S. S. (2004) The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc. Natl. Acad. Sci. USA 101, 10284-10289.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10284-10289
-
-
Doublie, S.1
Bandaru, V.2
Bond, J.P.3
Wallace, S.S.4
-
53
-
-
0037435405
-
The enigma of endonuclease VIII
-
Wallace, S. S., Bandaru, V., Kathe, S. D. and Bond, J. P. (2003) The enigma of endonuclease VIII. DNA Repair (Amst) 2, 441-453.
-
(2003)
DNA Repair (Amst)
, vol.2
, pp. 441-453
-
-
Wallace, S.S.1
Bandaru, V.2
Kathe, S.D.3
Bond, J.P.4
-
54
-
-
18644363009
-
hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
-
Kavli, B., Sundheim, O., Akbari, M., Otterlei, M., Nilsen, H., Skorpen, F., Aas, P. A., Hagen, L., Krokan, H. E. and Slupphaug, G. (2002) hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup. J. Biol. Chem. 277, 39926-39936.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 39926-39936
-
-
Kavli, B.1
Sundheim, O.2
Akbari, M.3
Otterlei, M.4
Nilsen, H.5
Skorpen, F.6
Aas, P.A.7
Hagen, L.8
Krokan, H.E.9
Slupphaug, G.10
-
55
-
-
0029904839
-
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
-
Slupphaug, G., Mol, C. D., Kavli, B., Arvai, A. S., Krokan, H. E. and Tainer, J. A. (1996) A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature 384, 87-92.
-
(1996)
Nature
, vol.384
, pp. 87-92
-
-
Slupphaug, G.1
Mol, C.D.2
Kavli, B.3
Arvai, A.S.4
Krokan, H.E.5
Tainer, J.A.6
-
56
-
-
0034625082
-
Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
-
Parikh, S. S., Walcher, G., Jones, G. D., Slupphaug, G., Krokan, H. E., Blackburn, G. M. and Tainer, J. A. (2000) Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects. Proc. Natl. Acad. Sci. USA 97, 5083-5088.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5083-5088
-
-
Parikh, S.S.1
Walcher, G.2
Jones, G.D.3
Slupphaug, G.4
Krokan, H.E.5
Blackburn, G.M.6
Tainer, J.A.7
-
57
-
-
0038771139
-
Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1
-
Wibley, J. E., Waters, T. R., Haushalter, K., Verdine, G. L. and Pearl, L. H. (2003) Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1. Mol. Cell 11, 1647-1659.
-
(2003)
Mol. Cell
, vol.11
, pp. 1647-1659
-
-
Wibley, J.E.1
Waters, T.R.2
Haushalter, K.3
Verdine, G.L.4
Pearl, L.H.5
-
58
-
-
0033575886
-
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
-
Hendrich, B., Hardeland, U., Ng, H. H., Jiricny, J. and Bird, A. (1999) The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 401, 301-304.
-
(1999)
Nature
, vol.401
, pp. 301-304
-
-
Hendrich, B.1
Hardeland, U.2
Ng, H.H.3
Jiricny, J.4
Bird, A.5
-
59
-
-
0038475941
-
Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
-
Wu, P., Qiu, C., Sohail, A., Zhang, X., Bhagwat, A. S. and Cheng, X. (2003) Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4. J. Biol. Chem. 278, 5285-5291.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 5285-5291
-
-
Wu, P.1
Qiu, C.2
Sohail, A.3
Zhang, X.4
Bhagwat, A.S.5
Cheng, X.6
-
60
-
-
0035233134
-
Thymine DNA glycosylase
-
Hardeland, U., Bentele, M., Lettieri, T., Steinacher, R., Jiricny, J. and Schar, P. (2001) Thymine DNA glycosylase. Prog. Nucleic Acid Res. Mol. Biol. 68, 235-253.
-
(2001)
Prog. Nucleic Acid Res. Mol. Biol
, vol.68
, pp. 235-253
-
-
Hardeland, U.1
Bentele, M.2
Lettieri, T.3
Steinacher, R.4
Jiricny, J.5
Schar, P.6
-
61
-
-
20544440797
-
Crystal structure of thymine DNA glycosylase conjugated to SUMO-1
-
Baba, D., Maita, N., Jee, J. G., Uchimura, Y., Saitoh, H., Sugasawa, K., Hanaoka, F., Tochio, H., Hiroaki, H. and Shirakawa, M. (2005) Crystal structure of thymine DNA glycosylase conjugated to SUMO-1. Nature 435, 979-982.
-
(2005)
Nature
, vol.435
, pp. 979-982
-
-
Baba, D.1
Maita, N.2
Jee, J.G.3
Uchimura, Y.4
Saitoh, H.5
Sugasawa, K.6
Hanaoka, F.7
Tochio, H.8
Hiroaki, H.9
Shirakawa, M.10
-
62
-
-
0030861915
-
DNA glycosylases in the base excision repair of DNA
-
Krokan, H. E., Standal, R. and Slupphaug, G. (1997) DNA glycosylases in the base excision repair of DNA. Biochem. J. 325 (Pt 1), 1-16.
-
(1997)
Biochem. J
, vol.325
, Issue.PART 1
, pp. 1-16
-
-
Krokan, H.E.1
Standal, R.2
Slupphaug, G.3
-
63
-
-
0034576553
-
The alpha/beta fold uracil DNA glycosylases: A common origin with diverse fates
-
RESEARCH0007
-
Aravind, L. and Koonin, E. V. (2000) The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates. Genome Biol. 1, RESEARCH0007.
-
(2000)
Genome Biol
, vol.1
-
-
Aravind, L.1
Koonin, E.V.2
-
64
-
-
13744252890
-
MAFFT version 5: Improvement in accuracy of multiple sequence alignment
-
Katoh, K., Kuma, K., Toh, H. and Miyata, T. (2005) MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res. 33, 511-518.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 511-518
-
-
Katoh, K.1
Kuma, K.2
Toh, H.3
Miyata, T.4
-
65
-
-
1342288004
-
The Jalview Java alignment editor
-
Clamp, M., Cuff, J., Searle, S. M. and Barton, G. J. (2004) The Jalview Java alignment editor. Bioinformatics 20, 426-427.
-
(2004)
Bioinformatics
, vol.20
, pp. 426-427
-
-
Clamp, M.1
Cuff, J.2
Searle, S.M.3
Barton, G.J.4
-
66
-
-
0033105094
-
Conserved domains in DNA repair proteins and evolution of repair systems
-
Aravind, L., Wallace, R. and Koonin, E. V. (1999) Conserved domains in DNA repair proteins and evolution of repair systems. Nucleic Acids Res. 27, 1223-1242.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 1223-1242
-
-
Aravind, L.1
Wallace, R.2
Koonin, E.V.3
-
67
-
-
33845522879
-
Organ and cell specificity of base excision repair mutants in mice
-
Larsen, E., Meza, T. J., Kleppa, L. and Klungland, A. (2007) Organ and cell specificity of base excision repair mutants in mice. Mutat. Res. 614, 56-68.
-
(2007)
Mutat. Res
, vol.614
, pp. 56-68
-
-
Larsen, E.1
Meza, T.J.2
Kleppa, L.3
Klungland, A.4
-
68
-
-
5044247389
-
-
Friedberg, E. C. and Meira, L. B. (2004) Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6). DNA Repair (Amst) 3, 1617-1638.
-
Friedberg, E. C. and Meira, L. B. (2004) Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6). DNA Repair (Amst) 3, 1617-1638.
-
-
-
-
69
-
-
0033636312
-
Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication
-
Nilsen, H., Rosewell, I., Robins, P., Skjelbred, C. F., Andersen, S., Slupphaug, G., Daly, G., Krokan, H. E., Lindahl, T. and Barnes, D. E. (2000) Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication. Mol. Cell 5, 1059-1065.
-
(2000)
Mol. Cell
, vol.5
, pp. 1059-1065
-
-
Nilsen, H.1
Rosewell, I.2
Robins, P.3
Skjelbred, C.F.4
Andersen, S.5
Slupphaug, G.6
Daly, G.7
Krokan, H.E.8
Lindahl, T.9
Barnes, D.E.10
-
70
-
-
0041639515
-
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas
-
Nilsen, H., Stamp, G., Andersen, S., Hrivnak, G., Krokan, H. E., Lindahl, T. and Barnes, D. E. (2003) Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas. Oncogene 22, 5381-5386.
-
(2003)
Oncogene
, vol.22
, pp. 5381-5386
-
-
Nilsen, H.1
Stamp, G.2
Andersen, S.3
Hrivnak, G.4
Krokan, H.E.5
Lindahl, T.6
Barnes, D.E.7
-
71
-
-
0037076208
-
AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization
-
Rada, C., Jarvis, J. M. and Milstein, C. (2002) AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization. Proc. Natl. Acad. Sci. USA 99, 7003-7008.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7003-7008
-
-
Rada, C.1
Jarvis, J.M.2
Milstein, C.3
-
72
-
-
0142092610
-
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
-
Imai, K., Slupphaug, G., Lee, W.I., Revy, P., Nonoyama, S., Catalan, N., Yel, L., Forveille, M., Kavli, B., Krokan, H. E. et al. (2003) Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Nat. Immunol. 4, 1023-1028.
-
(2003)
Nat. Immunol
, vol.4
, pp. 1023-1028
-
-
Imai, K.1
Slupphaug, G.2
Lee, W.I.3
Revy, P.4
Nonoyama, S.5
Catalan, N.6
Yel, L.7
Forveille, M.8
Kavli, B.9
Krokan, H.E.10
-
73
-
-
12944252969
-
Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice
-
Minowa, O., Arai, T., Hirano, M., Monden, Y., Nakai, S., Fukuda, M., Itoh, M., Takano, H., Hippou, Y., Aburatani, H. et al. (2000) Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. Proc. Natl. Acad. Sci. USA 97, 4156-4161.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4156-4161
-
-
Minowa, O.1
Arai, T.2
Hirano, M.3
Monden, Y.4
Nakai, S.5
Fukuda, M.6
Itoh, M.7
Takano, H.8
Hippou, Y.9
Aburatani, H.10
-
74
-
-
2342520175
-
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
-
Xie, Y., Yang, H., Cunanan, C., Okamoto, K., Shibata, D., Pan, J., Barnes, D. E., Lindahl, T., McIlhatton, M., Fishel, R. et al. (2004) Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res. 64, 3096-3102.
-
(2004)
Cancer Res
, vol.64
, pp. 3096-3102
-
-
Xie, Y.1
Yang, H.2
Cunanan, C.3
Okamoto, K.4
Shibata, D.5
Pan, J.6
Barnes, D.E.7
Lindahl, T.8
McIlhatton, M.9
Fishel, R.10
-
75
-
-
0026684849
-
Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA
-
Michaels, M. L., Cruz, C., Grollman, A. P. and Miller, J. H. (1992) Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA. Proc. Natl. Acad. Sci. USA 89, 7022-7025.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7022-7025
-
-
Michaels, M.L.1
Cruz, C.2
Grollman, A.P.3
Miller, J.H.4
-
76
-
-
0031660080
-
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate
-
Elder, R. H., Jansen, J. G., Weeks, R. J., Willington, M. A., Deans, B., Watson, A. J., Mynett, K. J., Bailey, J. A., Cooper, D. P., Rafferty, J. A. et al. (1998) Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate. Mol. Cell Biol. 18, 5828-5837.
-
(1998)
Mol. Cell Biol
, vol.18
, pp. 5828-5837
-
-
Elder, R.H.1
Jansen, J.G.2
Weeks, R.J.3
Willington, M.A.4
Deans, B.5
Watson, A.J.6
Mynett, K.J.7
Bailey, J.A.8
Cooper, D.P.9
Rafferty, J.A.10
-
77
-
-
0030041960
-
Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing
-
Engelward, B. P., Dreslin, A., Christensen, J., Huszar, D., Kurahara, C. and Samson, L. (1996) Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing. EMBO J. 15, 945-952.
-
(1996)
EMBO J
, vol.15
, pp. 945-952
-
-
Engelward, B.P.1
Dreslin, A.2
Christensen, J.3
Huszar, D.4
Kurahara, C.5
Samson, L.6
-
78
-
-
37549004382
-
Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1
-
Prasad, A., Wallace, S. S. and Pederson, D. S. (2007) Initiation of base excision repair of oxidative lesions in nucleosomes by the human, bifunctional DNA glycosylase NTH1. Mol. Cell Biol. 27, 8442-8453.
-
(2007)
Mol. Cell Biol
, vol.27
, pp. 8442-8453
-
-
Prasad, A.1
Wallace, S.S.2
Pederson, D.S.3
-
79
-
-
0037934742
-
Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes
-
Beard, B. C., Wilson, S. H. and Smerdon, M. J. (2003) Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. Proc. Natl. Acad. Sci. USA 100, 7465-7470.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7465-7470
-
-
Beard, B.C.1
Wilson, S.H.2
Smerdon, M.J.3
-
80
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky, R., Chua, K. F., Lombard, D. B., Pang, W. W., Fischer, M. R., Gellon, L., Liu, P., Mostoslavsky, G., Franco, S., Murphy, M. M. et al. (2006) Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124, 315-329.
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
-
81
-
-
10944251591
-
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
-
Barnes, D. E. and Lindahl, T. (2004) Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu. Rev. Genet. 38, 445-476.
-
(2004)
Annu. Rev. Genet
, vol.38
, pp. 445-476
-
-
Barnes, D.E.1
Lindahl, T.2
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