OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

Nature

Volumn 447, Issue 7143, 2007, Pages 447-452

  Kovtun, Irina V ^a   Liu, Yuan ^e   Bjoras, Magnar ^d   Klungland, Arne ^d   Wilson, Samuel H ^e   McMurray, Cynthia T ^a,b,c  

^a Department of Pharmacology and Experimental Therapeutics ^*  (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF OSLO   (Norway)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 8 OXOGUANINE DNA GLYCOSYLASE 1; ENZYME; HUNTINGTON DISEASE PROTEIN; HYDROGEN PEROXIDE; PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

AGE; ENZYME ACTIVITY; MUTATION; NERVOUS SYSTEM DISORDER; OXIDATION; PHENOTYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DNA STRAND BREAKAGE; EXCISION REPAIR; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SOMATIC CELL; STATISTICAL SIGNIFICANCE; TRANSGENIC MOUSE;

EID: 34249337762     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05778     Document Type: Article

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