Minor components of pulses and their potential impact on human health

Food Research International

Volumn 43, Issue 2, 2010, Pages 461-482

  Campos Vega, Rocio ^a   Loarca Piña, Guadalupe ^a   Oomah, B Dave ^b  

^a UNIVERSIDAD AUTÓNOMA DE QUERÉTARO   (Mexico)

^b SUMMERLAND RESEARCH AND DEVELOPMENT CENTRE   (Canada)

Author keywords

Cancer; Cardiovascular diseases; Diabetes; Enzyme inhibitors; Fatty acids; Galactooligosaccharides; Human health; Lectins; Legumes; Minerals; Obesity; Oxalate; Phenolic compounds; Phytic acid; Phytoesterols; Pulses; Saponins; Vitamins

Indexed keywords

CARDIO-VASCULAR DISEASE; CARDIOVASCULAR DISEASES; ENZYME INHIBITORS; GALACTO-OLIGOSACCHARIDES; HUMAN HEALTH; LECTINS; PHENOLIC COMPOUNDS; PHYTIC ACIDS;

BIOCHEMISTRY; CELL DEATH; ENZYMES; FATTY ACIDS; HEALTH; METABOLISM; METABOLITES; MINERALS; NUTRITION; PHENOLS; SILICATE MINERALS; SULFUR COMPOUNDS; VITAMINS;

ACIDS;

EID: 75449086814     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodres.2009.09.004     Document Type: Review

References (274)

1. Adlercreutz H. Human health and phytoestrogens. In: Korach K.S. (Ed). Reproductive and developmental toxicology (1998), Marcel Dekker, New York 299-371
2. Agharkar S.P. Medicinal plants of Bombay presidency (1991), India Scientific Publishers, Jodhpur, India
3. Agurs-Collins T., Smoot D., Afful J., Makambi K., and Adams-Campbell L. Legume intake and reduced colorectal adenoma risk in African-Americans. Journal of National Black Nurses Association 17 (2006) 6-12
4. Akpinar N., Akpinar M.A., and Türkoǧlu S. Total lipid content and fatty acid composition of the seeds of some Vicia L. species. Food Chemistry 74 (2001) 449-453
5. Allen L.H. Calcium bioavailability and absorption: A review. The American Journal of Clinical Nutrition 35 (1982) 783-808
6. Amarowicz R., Troszynska A., Barylko-Pikielna N., and Shahidi F. Extracts of polyphenolics from legume seeds - Correlation between their total antioxidant activity, total phenolics content, tannins content and astringency. Journal of Food Lipids 11 (2004) 278-286
7. American Heart Association. Heart disease and stroke statistics - 2009 update (2009), Dallas, TX
8. Aubert M., Panicot L., Crotte C., Gibier P., Lombardo D., Sadoulet M.O., et al. Restoration of alpha (1,2) fucosyltransferase activity decreases adhesive and metastatic properties of human pancreatic cancer cells. Cancer Research 60 (2000) 1449-1456
9. Augustin J., Beck C.B., Kalbfleish G., Kagel L.C., and Matthews R.H. Variation in the vitamin and mineral content of raw and cooked commercial Phaseolus vulgaris classes. Journal of Food Science 46 (1981) 1701-1706
10. Avila M.A., Velasco J.A., Cansado J., and Notario V. Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468. Cancer Research 54 (1994) 2424-2428
11. Awika J.M., Rooney L.W., Wu X., Prior R.L., and Zevallos L.C. Screening methods to measure antioxidant activity of sorghum (Sorghum bicolor) and sorghum products. Journal of Agricultural and Food Chemistry 51 (2003) 6657-6662
12. Azevedo A., Gomes J.C., Stringheta P.C., Gontijo A.M.C., Padovani C.R., Riberio L.R.Z., et al. Black bean (Phaseolus vulgaris L.) as a protective agent against DNA damage in mice. Food and Chemical Toxicology 41 (2003) 1671-1676
13. Balint G.A. Ultrastructural study of liver cell damage induced by ricin. Experimental and Toxicologic Pathology 52 (2000) 413-417
14. Barceló A.R., and Muñoz R. Epigenetic control of a cell wall scopoletin peroxidase by lupisoflavone in Lupinus. Phytochemistry 28 (1989) 1331-1333
15. Bardocz S., Grant G., Duguid T.J., Brown D.S., Pusztai A., and Pryme I.F. Intracellular levels of polyamines in Krebs II lymphosarcoma cells in mice fed phytohaemagglutinin-containing diets are coupled with altered tumour growth. Cancer Letters 121 (1997) 25-29
16. Bazzano L.H.J., Ogden L.G., Loria C., Vupputuri S., Myers L., and Whelton P.K. Legume consumption and risk of coronary heart disease in US men and women: NHANES I Epidemiologic Follow-up Study. Archives of Internal Medicine 161 (2001) 2573-2578
17. Belitz H.D., and Weder J.K.P. Protein inhibitors of hydrolases in plants foodstuffs. Food Reviews International 6 (1990) 151-211
18. Benveniste P. Sterol biosynthesis. Annual Review of Plant Physiology 37 (1986) 275-308
19. Berdanier C.D. Is inositol an essential nutrient?. Nutrition Today 27 (1992) 22-26
20. Bertrand D., Delort-Laval J., Melcion J.P., and Valdebouze P. Influence de l'extrusion et de l'infranisation sur les facteurs antinutritionnels et la valeur alimentaire du pois (Pisum sativum L.). Sciences des Aliments 2 Suppl (1982) 197-202
21. Bird T.A., Schule H.D., Delaney P.B., Sims J.E., Thoma B., and Dower S.K. Evidence that MAP (mitogen-activated protein) kinase activation may be a necessary but not sufficient signal for a restricted subset of responses in IL-1-treated epidermoid cells. Cytokine 4 (1992) 429-440
22. Blask D.E., Hill S.M., Orstead K.M., and Massa J.S. Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotional phase of 7,12-dimethylbenzanthracene (DMBA)-induced mammary carcinogenesis. Journal of Neural Transmission 67 (1986) 125-138
23. Blask D.E., Sauer L.A., and Dauchy R.T. Melatonin as a chronobiotic/anticancer agent: Cellular biochemical and molecular mechanisms of action and their implications for circadian-based cancer therapy. Current Topics in Medicinal Chemistry 2 (2002) 113-133
24. Bond D.A., and Duc G. Plant breeding as a means of reducing antinutritional factors of grain legumes. In: Van der Poel A., Huisman J., and Saini H.S. (Eds). Recent advances of research in antinutritional factors in legume seeds, proceedings of the 2nd international workshop on antinutritional factors (ANFs) in legume seeds (1993), Wageningen Press, Wageningen, Netherlands 379-396
25. Cabrera C., Lloris F., Giménez R., Olalla M., and López M.C. Mineral content in legumes and nuts: Contribution to the Spanish dietary intake. The Science of the Total Environment 308 (2003) 1-14
26. Cai Y., Luo Q., Sun M., and Corke H. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sciences 74 (2004) 2157-2184
27. Campbell W.W., Ostlund R.E., Joseph L.J., Farrell E.A., and Evans W.J. Relationships of plasma C-peptide and gender to the urinary excretion of inositols in older people. Hormone and Metabolic Research 33 (2001) 44-51
28. Campion B., Perrone D., Galasso I., and Bollini R. Common bean (Phaseolus vulgaris L.) lines devoid of major lectin proteins. Plant Breeding 128 (2009) 199-204
29. Cardador-Martinez A., Loarca-Pina G., and Oomah B.D. Antioxidant activity in common beans. Journal of Agricultural and Food Chemistry 50 (2002) 6975-6980
30. Carstensen S., Pliska Matyshak G., Bhuvarahamurthy N., Robbins K.M., and Murthy E.P.N. Biosynthesis and localization of phosphatidyl-scyllo-inositol in barley aleurone cells. Lipids 34 (1999) 67-73
31. Cassidy A., Albertazzi P., Lise Nielsen I., Hall W., Williamson G., Tetens I., et al. Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women. The Proceedings of the Nutrition Society 65 (2006) 76-92
32. Celleno L., Tolaini M.V., D'Amore A., Perricone N.V., and Preuss H.G. A dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women. International Journal of Medical Sciences 4 (2007) 45-52
33. Champ M.M. Non-nutrient bioactive substances of pulses. British Journal of Nutrition 88 Suppl. 3 (2002) S307-S319
34. Chang R.L., Huang M.T., Wood A.W., Wong C.Q., Newmark H.L., Yagi H., et al. Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (6)-7 beta, 8 alphadihydroxy-9 alpha, 10 alpha epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse. Carcinogenesis 6 (1985) 1127-1133
35. Chang W.W., Yu C.Y., Lin T.W., Wang P.H., and Tsai Y.C. Soyasaponin I decreases the expression of alpha2,3-linked sialic acid on the cell surface and suppresses the metastatic potential of B16F10 melanoma cells. Biochemical and Biophysical Research Communications 341 (2006) 614-619
36. Chen Q.C. Determination of phytic acid and inositol pentakisphosphates in foods by high-performance ion chromatography. Journal of Agricultural and Food Chemistry 52 (2004) 4604-4613
37. Choi J.A., Kim J.Y., Lee J.Y., Kang C.M., Know H.J., Yoo Y.D., et al. Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. International Journal of Oncology 9 (2001) 837-844
38. Chung T.W., Moon S.K., Chang Y.C., Ko J.H., Lee Y.C., Cho G., et al. Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: Complete regression of hepatoma growth and metastasis by dual mechanism. The FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 18 (2004) 1670-1681
39. Chung K.T., Wong T.Y., Wei C.I., Huang Y.W., and Lin Y. Tannins and human health: A review. Critical Reviews in Food Science and Nutrition 38 (1998) 421-464
40. Chrenkova, M., Ceresnakova, Z., Sommer, A., & Slamena, Z. (2001). The nutritive value of new-bred varieties of pea grown in Slovakia, In Proceedings of the 4th European Conference on Grain Legumes, Cracow (pp. 114-115). Paris: AEP Editions.
41. Coskun O., Kanter M., Korkmaz A., and Oter S. Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and β-cell damage in rat pancreas. Pharmacological Research 51 (2005) 117-123
42. Cramer D.W., Kuper H., Harlow B.L., and Titus-Ernstoff L. Carotenoids, antioxidants and ovarian cancer risk in pre- and postmenopausal women. International Journal of Cancer 94 (2001) 128-134
43. Cuadrado C., Hajos G., Burbano C., Pedrosa M.M., Ayet G., Muzquiz M., et al. Effect of natural fermentation on the lectin of lentils measured by immunological methods. Food and Agricultural Immunology 14 (2002) 41-49
44. Dang J., Arcot J., and Shrestha A. Folate retention in selected processed legumes. Food Chemistry 68 (2000) 295-298
45. Daveby Y.D.A.P., Betz J.M., and Musser S.M. Effect of storage and extraction on ratio of soyasaponin I to 2,3-dihydro-2,5-dihydroxy-6-methyl-4-pyrone-conjugated soyasaponin I in de-hulled peas (Pisum sativum L.). Journal of the Science of Food and Agriculture 32 (1998) 141-146
46. De Boever P., Deplancke B., and Verstraete W. Fermentation by gut microbiota cultured in a simulator of the human intestinal microbial ecosystem is improved by supplementing a soygerm powder. Journal of Nutrition 130 (2000) 2599-2606
47. De Muelenaere H.J. Toxicity and haemagglutining activity of legumes. Nature 206 (1965) 827-828
48. Dini I., Schettino O., and Dini A. Studies on the constituents of Lupinus mutabilis (Fabaceae). Isolation and characterization of two new isoflavonoid derivatives. Journal of Agricultural and Food Chemistry 46 (1998) 5089-5092
49. Dintzis F.R., Lehrfeld J., Nelsen T.C., and Finney P.L. Phytate content of soft wheat brans as related to kernel size, cultivar, location, and milling and flour quality parameters. Cereal Chemistry 69 (1992) 577-581
50. Duane W.C. Effects of legume consumption on serum cholesterol, biliary lipids, and sterol metabolism in humans. Journal of Lipid Research 38 (1997) 1120-1128
51. Duhan A., Khetarpaul N., and Bishnoi S. Saponin content and trypsin inhibitor activity in processed and cooked pigeon pea cultivars. International Journal of Food Science and Nutrition 52 (2001) 53-59
52. Duranti M. Grain legume proteins and nutraceutical properties. Fitoterapia 77 (2006) 67-82
53. Einat H., and Belmaker R.H. The effects of inositol treatment in animal models of psychiatric disorders. Journal of Affective Disorders 62 (2001) 113-121
54. Eitenmiller R.R., and Lee J. Vitamin E: Food chemistry, composition and analysis (2004), Marcel Decker, New York
55. Ekpenyoung T.E., and Borchers R.L. Some toxic factors in winged bean seeds. Nutrition Reports International 23 (1981) 865-870
56. El-Adawy T.A. Nutritional composition and antinutritional factors of chickpeas (Cicer arietinum L.) undergoing different cooking methods and germination. Plant Foods for Human Nutrition 57 (2002) 83-97
57. Elhardallon S.B., and Walker A.F. Binding of iron by three starchy legumes in the presence of iron alone, with calcium or with calcium, zinc, magnesium and copper. Journal of Food Sciences and Nutrition 43 (1992) 61-68
58. Ellington A.A., Berhow M.A., and Singletary K.W. Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells. Carcinogenesis 27 (2006) 289-306
59. Estensen R.D., and Wattenberg L.W. Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice. Carcinogenesis 14 (1993) 1975-1977
60. Feinberg M., Favier J.C., and Ireland-Ripert J. Repértoir e general des aliments: Table de composition (1995), Institut National de la Recherche Agronomique, Paris
61. Fennema O.R. Food chemistry (2000), Marcel Dekker, New York
62. Fenwick D.E., and Oakenfull D. Saponin content of food plants and some prepared foods. Journal of the Science of Food and Agriculture 34 (1983) 186-191
63. Feregrino-Perez A.A., Berumen L.C., Garcia-Alcocer G., Guevara-Gonzalez R.G., Ramos-Gomez M., Reynoso-Camacho R., et al. Composition and chemopreventive effect os polysaccharides from common beans (Phaseolus vulgaris L.) on azoxymethane-induced colon cancer. Journal of Agricultural and Food Chemistry 56 (2008) 8737-8744
64. Ferriola P.C., Cody V., and Middleton E. Protein kinase C inhibition by plant flavonoids, kinetic mechanism and structure-activity relationships. Biochemical Pharmacology 38 (1989) 1617-1624
65. Finley J.W., Burrell J.B., and Reeves P.G. Pinto bean consumption changes SCFA profiles in fecal fermentations, bacterial populations of the lower bowel, and lipid profiles in blood of humans. Journal of Nutrition 137 (2007) 2391-2398
66. Flight I., and Clifton P. Cereal grains and legumes in the prevention of coronary heart disease and stroke: A review of the literature. European Journal of Clinical Nutrition 60 (2006) 1145-1159
67. Fredlund K., Isaksson M., Rossander-Hulthén L., Almgren A., and Sandberg A.-S. Absorption of zinc and retention of calcium: Dose-dependent inhibition by phytate. Journal of Trace Elements in Medical Biology 20 (2006) 49-57
68. Fukui H., Egawa H., and Koshimizu K. A new isoflavone with antifungal activity from immature fruits of Lupinus luteus. Agricultural and Biological Chemistry 37 (1973) 417-421
69. Fung T., Hu F.B., Fuchs C., Giovannucci E., Hunter D.J., Stampher M.J., et al. Major dietary patterns and the risk of colorectal cancer in women. Archives of Internal Medicine 163 (2003) 309-314
70. Geil P.B., and Anderson J.W. Nutrition and health implications of dry beans: A review. Journal of the American College of Nutrition 13 (1994) 549-558
71. Genovese, M. I., & Lajolo, F. M. (1998). Inibidores de tripsina do feijaõ (Phaseolus vulgaris): Isoformas e estabilidade térmica. Anais XVI Congresso Brasileiro Ciência e Tecnologia de Alimentos. Brazil, Sociedade Brasileira de Ciência eTechnologia de Alimentos (SBCTA), Rio de Janeiro.
72. Giovannucci E., Stampfer M.J., Colditz G.A., Hunter D.J., Fuchs C., Rosner B.A., et al. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study. Annals of Internal Medicine 129 (1998) 517-524
73. Giovannucci E., and Willett W.C. Dietary factors and risk of colon cancer. Annals of Medicine 26 (1994) 443-452
74. Gitto E., Malgorzata K., Russel J.R., Dun X.T., Cuzzocrea S., Chiurazzi P., et al. Effects of melatonin treatment on septic newborns. Pediatrics Research 50 (2001) 756-760
75. Glore S.R., Van Treeck D., Knehans A.W., and Guild M. Soluble fiber and serum lipids: A literature review. Journal of the American Dietetic Association 94 (1994) 425-436
76. Godlewski M.M., Slazak P., Zabielski R., Piastowska A., and Gralak M.A. Quantitative study of soybean-induced changes in proliferation and programmed cell death in the intestinal mucosa of young rats. Journal of Physiology and Pharmacology 57 (2006) 125-133
77. González De Mejía E., and Prisecaru V.I. Lectins as bioactive plant proteins: A potential in cancer treatment. Critical Reviews in Food Science and Nutrition 45 (2005) 425-445
78. González de Mejía E., Rocha N., Winter H.C., and Goldstein I.J. Differential effect of a lectin from mesquite (Prosopis juliflora) on HeLa and normal human keratinocyte cells. The FASEB Journal 15 (2002) C128
79. Graf E., and Eaton J.W. Antioxidant functions of phytic acid. Free Radical Biology and Medicine 8 (1990) 61-69
80. Grant G., Alonso R., Edwards J.E., and Murray S. Dietary soya beans and kidney beans stimulate secretion of cholecystokinin and pancreatic digestive enzymes in 400-day-old Hooded-Lister rats but only soya beans induce growth of the pancreas. Pancreas 20 (2000) 305-312
81. Grant G., Dorward P.M., Buchan W.C., Armour J.C., and Pusztai A. Consumption of diets containing soya beans (Glycine max), kidney beans (Phaseolus vulgaris), cowpeas (Vigna unguiculata) or lupin seeds (Lupinus augustifolius) by rats for up to 700 days: Effects on body composition and organ weights. British Journal of Nutrition 73 (1995) 17-29
82. Grant G., Edwards J.E., and Pusztai A. α-Amylase inhibitor levels in seeds generally available in Europe. Journal of the Science of Food and Agriculture 67 (1995) 235-238
83. Grases F., Costa-Bauza A., Perelló J., Isern B., Vucenik I., Valiente M., et al. Influence of concomitant food intake on the excretion of orally administered myo-inositol hexaphosphate in humans. Journal of Medicinal Food 9 (2006) 72-76
84. Grases F., Simonet B.M., Vucenik I., Prieto R.M., Costa-Bauza A., March J.G., et al. Absorption and excretion of orally administered inositol hexaphosphate (IP6 or phytate) in humans. BioFactors 15 (2001) 53-61
85. Greenwood D., Cade J., Draper A., Barrett J.H., Calvert C., and Greenhalgh A. Seven unique food consumption patterns identified among women in the UK women's cohort study. European Journal of Clinical Nutrition 54 (2000) 314-320
86. Grela E.R., and Gunter K.D. Fatty acid composition and tocopherol content of some legume seeds. Animal Feed Science and Technology 52 (1995) 325-331
87. Gueguen J., Quemener B., and Valdebouze P. Elimination of antinutritional factors of faba bean (Vicia faba L.) and peas (Pisum sativum L.) during the preparation of protein isolates. Lebensmittel Wissenschaft und-Technologie 13 (1980) 443-455
88. Gurfinkel D.M., and Rao A.V. Soyasaponins: The relationship between chemical structure and colon anticarcinogenic activity. Nutrition and Cancer 47 (2003) 24-33
89. Gylling H., and Miettinen T.A. The effect of plant stanol- and sterol-enriched foods on lipid metabolism, serum lipids and coronary heart disease. Annals of Clinical Biochemistry 42 (2005) 254-263
90. Habiba R.A. Changes in anti-nutrients, protein solubility, digestibility and HCl-extractability of ash and phosphorus in vegetable peas as affected by cooking methods. Food Chemistry 77 (2002) 187-192
91. Harborne J., Boulter D., and Turner B.E. Chemotaxonomy of the leguminosae (1971), Academic Press, London
92. Harland J. Prevention is better than cure (soya isoflavones). Liquid Food and Drink Technology 1 (2002)
93. Hatano T., Yamashita A., Hashimoto T., Oto H., Kubo N., Yoshiyama M., et al. Flavan dimers with lipase inhibitory activity from Cassia Nomane. Phytochemistry 46 (1997) 893-900
94. Haveman-Nies A., Tucker K., De Groot L., Wilson P.W.F., and van Staveren W.A. Evaluation of dietary quality in relationship to nutritional and lifestyle factors in elderly people in the US Framingham Heart Study and the European SENECA study. European Journal of Clinical Nutrition 55 (2001) 870-880
95. Heimler D., Vignolini P., Dini M.G., and Romani A. Rapid tests to assess the antioxidant activity of Phaseolus vulgaris L. dry beans. Journal of Agricultural and Food Chemistry 53 (2005) 3053-3056
96. Herrera J.N.M., Romero F., and Rodríguez-Iturbe B. Melatonin prevents oxidative stress resulting from iron and erythropoietin administration. American Journal of Kidney Diseases 37 (2001) 750-757
97. Holland B., Unwin I.D., and Buss D.H. First supplement to McCance and Widdowson's. The composition of foods. 5th ed. (1992), Royal Society of Chemistry, Cambridge
98. Hönow R., and Hesse A. Comparison of extraction methods for the determination of soluble and total oxalate in foods by HPLC-enzyme-reactor. Food Chemistry 78 (2002) 511-521
99. Huisman, J. (1990). Antinutritional effects of legume seeds in piglets, rats and chickens. PhD thesis, Wageningen, The Netherlands.
100. Hurrell R.F., Reddy M., and Cook J.D. Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages. British Journal of Nutrition 81 (1999) 289-295
101. Ikeda I., Imasato Y., Sasaki E., Nakayama M., Nagao H., Takeo T., et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochimica et Biophysica Acta 1127 (1992) 141-146
102. Jacobs D.R.J., Andersen F.L., and Blomhoff R. Whole-grain consumption is associated with a reduced risk of noncardiovascular, noncancer death attributed to inflammatory diseases in the Iowa Women's Health Study. American Journal of Clinical Nutrition 85 (2007) 1606-1614
103. Jang Y., Lee J.H., Kim O.Y., Park H.Y., and Lee S.Y. Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease: Randomized controlled clinical trial. Arteriosclerosis, Thrombosis, and Vascular Biology 21 (2001) 2065-2071
104. Jenab M., and Thompson L.U. The influence of phytic acid in wheat bran on early biomarkers of colon carcinogenesis. Carcinogenesis 19 (1998) 1087-1092
105. Jenab M., and Thompson L.U. Role of phytic acid in cancer and other diseases in food phytates (2002), Boca Raton, CRC Press pp. 225-248
106. Jimenez A., Cervera P., and Bacardí M. Tabla de composición de alimentos (1998), Novartis Nutrition, Bacelona
107. Jimenez-Cruz A., Bacardi-Gascon M., Turnbull W.H., Rosales-Garay P., and Severino-Lugo I. A flexible, low-glycemic index, Mexican-style diet in overweight and obese subjects with type 2 diabetes improves metabolic parameters during a 6-week treatment period. Diabetes Care 26 (2003) 1967-1970
108. Jondreville C., Grosjean F., Buron G., Peyronnet C., and Beneytout J.L. Comparison of four pea varieties in pig feeding through digestibility and growth performance results. Journal of Animal Physiology and Animal Nutrition 68 (1992) 113-122
109. Jordinson M., El-Hariry I., Calnan D., Calam J., and Pignatelli M. Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells. Gut 44 (1999) 709-714
110. Kadam S.S., and Salunkhe D.K. Minerals and vitamins. In: Salunkhe D.K. (Ed). Handbook of world food legumes (1989), CRC Press, Boca Raton 117-121
111. Kataria A., Chauhan B.M., and Punia D. Antinutrients in amphidiploids (black gram × Mung bean): Varietal differences and effect of domestic processing and cooking. Plant Foods for Human Nutrition 39 (1989) 257-266
112. Kawabata K., Yamamoto T., Hara A., Shimizu M., Yamada Y., Matsunaga K., et al. Modifying effects of ferulic acid on azoxymethane-induced colon carcinogenesis in F344 rats. Cancer Letters 157 (2000) 15-21
113. Khokar S.N., Muzaffar A.K., and Chaudhri M.F. Some characters of chickpea-modulating Rhizobia native to thai soil. Journal of Biological Sciences 4 (2001) 1016-1019
114. Khokhar S., and Chauhan B.M. Antinutritional factors in moth bean: Varietal differences and effects of methods of domestic processing and cooking. Journal of Food Science 51 (1986) 591-594
115. Kim J.S., Kwon C.S., and Son K.H. Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid. Bioscience, Biotechnology, and Biochemistry 64 (2000) 2458-2461
116. Kjaer T.M., and Frokiaer H. Modulation of ovomucoid-specific tolerance in mice fed plant extracts containing lectins. British Journal of Nutrition 88 (2002) 671-680
117. Kofman O., Einat H., Cohen H., Tenne H., and Shoshana C. The anxiolytic effect of chronic inositol depends on the baseline level of anxiety. Journal of Neural Transmission 107 (2000) 241-253
118. Koh-Banerjee P., and Rimm E.B. Whole grain consumption and weight gain: A review of the epidemiological evidence, possible mechanisms and opportunities for further research. The Proceedings of the Nutrition Society 62 (2003) 25-29
119. Lacassagne L., Francesch M., Carré B., and Melcion J.P. Utilization of tannin-containing and tannin-free faba beans (Vicia faba) by young chicks: Effects of pelleting feeds on energy, protein and starch digestibility. Animal Feed Science and Technology 20 (1988) 59-68
120. Lajolo F.M., Finardi-Filho F., and Menezes E.W. Amylase inhibitors in Phaseolus vulgaris beans. Food Technology 45 (1991) 119-121
121. Lajolo F.M., and Genovese M.I. Nutritional significance of lectin and enzyme inhibitors from legumes. Journal of Agricultural and Food Chemistry 50 (2002) 6592-6598
122. Lajolo F.M., Mancini Filho J., and Menezes E.W. Effect of a bean (Phaseolus vulgaris) α-amylase inhibitor on starch utilization. Nutrition Reports International 30 (1984) 45-54
123. Lazze M.C., Pizzala R., Savio L.A., Stivala E.P., and Bianchi L. Anthocyanins protects against DNA damage induced by tert-butyl hydroperoxide in rat smooth muscle and hepatoma cells. Mutation Research 535 (2003) 103-115
124. Lee S., and Lee K.G. Inhibitory effects of volatile anti-oxidants found in various beans on malonaldehyde formation in horse blood plasma. Food and Chemical Toxicology 43 (2005) 515-520
125. Lee K., Shibamoto T., Takeoka G.R., Lee S.E., Kim J.H., and Park B.S. Inhibitory effects of plant-derived flavonoids and phenolic acids on malonaldehyde formation from ethyl arachidonate. Journal of Agricultural Chemistry 51 (2003) 7203-7207
126. Lerer-Metzger M., Rizkalla S., and Luo J. Effects of long-term low-glycemic index starchy food on plasma glucose and lipid concentrations and adipose tissue cellularity in normal and diabetic rats. British Journal of Nutrition 75 (1996) 723-732
127. Lewy A.J. Melatonin as a marker and phase-resetter of circadian rhythms in humans. Advances in Experimental Medicine and Biology 460 (1999) 425-434
128. Liener I.E. Legume toxins in relation to protein digestibility - a review. Journal of Food Science 41 (1976) 1076-1081
129. Liener I.E. Significance of humans of biologically active factors in soybeans and other food legumes. Journal of the American Oil Chemists' Society 56 (1979) 121-129
130. Liener I.E. Implications of antinutritional components in soybean foods. Critical Review in Food Science and Nutrition 34 (1994) 31-67
131. Lissoni P. Is there a role for melatonin in supportive care?. Support Care Cancer 10 (2002) 110-116
132. Littman A.J., Beresford S.A., and White E. The association of dietary fat and plant foods with endometrial cancer (United States). Cancer Causes and Control 12 (2001) 691-702
133. Loewus F.A., and Murthy P.P.N. Myo-inositol metabolism in plants. Plant Science 150 (2000) 1-19
134. Lombardi-Boccia G., Carbonaro M., Di Lullo G., and Carnovale E. Influence of protein components (G1, G2 and albumin) on Fe and Zn dialysability from bean (Phaseolus vulgaris L.). Journal of Food Sciences and Nutrition 45 (1994) 183-190
135. Long-Ze L., Harnly J.M., Pastor-Corrales M.S., and Luthria D.L. The polyphenolic profiles of common bean (Phaseolus vulgaris L.). Food Chemistry 107 (2008) 399-410
136. Lorea P., Goldschmidt D., Darro F., Salmon I., Bovin N., Gabius H.J., et al. In vitro characterization of lectin-induced alterations on the proliferative activity of three human melanoma cell lines. Melanoma Research 7 (1997) 353-363
137. Lucock M. Folic acid: Nutritional biochemistry, molecular biology, and role in disease processes. Molecular Genetics and Metabolism 71 (2000) 121-138
138. Luthria D.L., and Pastor-Corrales M.A. Phenolic acids content of fifteen dry edible bean (Phaseolus vulgaris L.) varieties. Journal of Food Composition and Analysis 19 (2006) 205-211
139. Malin A.S., Qi D., Shu X.O., Gao Y.T., Friedmann J.M., Jin F., et al. Intake of fruits, vegetables and selected micronutrients in relation to the risk of breast cancer. International Journal of Cancer 105 (2003) 413-418
140. Mancini F.J., and Lajolo F.M. Fatores antinutricionais em diferentes variedades de feijões (Phaseolus vulgaris L.). Ciencia e Cultura 33 (1981) 94-97
141. Mangiapane H., Thomson J., Salter A., Brown S., Bell G.D., and White D.A. The inhibition of the oxidation of low density lipoprotein by (1)-catechin, a naturally occurring flavonoid. Biochemical Pharmacology 43 (1992) 445-450
142. Maruyama C., Araki R., Kawamura M., Kondo N., Kigawa M., Kawai Y., et al. Azuki bean juice lowers serum triglyceride concentrations in healthy young women. Journal of Clinical Biochemistry and Nutrition 43 (2008) 19-25
143. Mason A.C., Weaver C.M., Kimmel S., and Brown R.K. Effect of soybean phytate content on calcium bioavailability in mature and immature rats. Journal of Agricultural Food Chemistry 41 (1993) 246-249
144. Massey L.K., Palmer R.G., and Horner H.T. Oxalate content of soybean seeds (glycine max: leguminosae), soyfoods, and other edible legumes. Journal of Agricultural and Food Chemistry 49 (2001) 4262-4266
145. Mataix, F. J., & Mañas, M. T. (1998). Tabla de composición de alimentos españoles. Instituto de Nutrición y Tecnología de los Alimentos-Universidad de Granada, Granada.
146. Mathers J.C. Pulses and carcinogenesis: Potential for prevention of colon, breast and other cancers. British Journal of Nutrition 88 (2002) 272-279
147. Mazur W.M., Duke J.A., Wahala K., Rasku S., and Adlercreutz H. Isoflavonoids and lignans in legumes: Nutritional and health aspects in humans. Journal of Nutritional Biochemistry 9 (1998) 193-200
148. McCann S.E., Freudenheim J.L., Marshall J.R., Brasure J.R., Swanson M.K., and Graham S. Diet in the epidemiology of endometrial cancer in Western New York (United States). Cancer Causes and Control 11 (2000) 965-974
149. McLaurin J., Golomb R., Jurewicz A., Antel J.P., and Fraser P.E. Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid 13 peptide and inhibit A 13-induced toxicity. Journal of Biological Chemistry 275 (2000) 18495-18502
150. Meagher L.P., and Beecher G.R. Assessment of data on the lignan content of foods. Journal of Food Composition and Analysis 13 (2000) 935-947
151. Melcion J.P., and Valdebouze P. Effect of various industrial treatments on the antinutritional factors of field bean (Vicia faba L.). Protein Quality from Leguminous Crops. Seminar in EEC Program (1977), Commission of the European Communities, Kirchberg, Luxembourg 116-124
152. Menezes E.W., and Lajolo F.M. Inhibition of starch digestion by a black bean α-amylase inhibitor, in normal and diabetic rats. Nutrition Reports International 36 (1987) 1185-1189
153. Messina M., McCaskill-Stevens W., and Lampe J.W. Addressing the soy and breast cancer relationship: Review, commentary, and workshop proceedings. Journal of the National Cancer Institute 98 (2006) 1275-1284
154. Midorikawa K., Murata M., Oikawa S., Hiraku Y., and Kawanishi S. Protective effect of phytic acid on oxidative DNA damage with reference to cancer chemoprevention. Biochemical Biophysical Research Communications 288 (2001) 552-557
155. Milgate J., and Roberts D.C.K. The nutritional & biological significance of saponins. Nutrition Research 15 (1995) 1223-1249
156. Minihane A.N., and Rimbach. Gerald Iron absorption and the iron binding and anti-oxidant properties of phytic acid. International Journal of Food Science and Technology 37 (2002) 741-748
157. Ministerio de Sanidad y Consumo (1999). Tablas de composición de alimentos españoles. Ministerio de Sanidad y Consumo. Boletín Oficial del Estado, Madrid.
158. Molis T.M., Spriggs L.L., Jupiter Y., and Hill S.M. Melatonin modulation of estrogen-regulated proteins, growth factors, and proto-oncogenes in human breast cancer. Journal of Pineal Research 18 (1995) 93-103
159. Morcos S.R., Gabriel G.N., and El-Hafez M.A. Nutritive studies on some raw and prepared leguminous seeds commonly used in the Arab Republic of Syria. Zeitschrift fuer Ernaehrungswissenschaft 15 (1976) 378-386
160. Morris E.R., and Hill A.D. Inositol phosphate content of selected dry beans, peas, and lentils, raw and cooked. Journal of Food Composition and Analysis 9 (1996) 2-12
161. Mubarak A.E. Nutritional composition and antinutritional factors of mung bean seeds (Phaseolus aureus) as affected by some home traditional processes. Food Chemistry 89 (2005) 489-495
162. Murphy P.A., and Hendrich S. Phytoestrogens in foods. Advances in Food and Nutrition Research 44 (2002) 195-246
163. Muzquiz M., Burbano C., Ayet G., Pedrosa M.M., and Cuadrado C. The investigation of antinutritional factors in Phaseolus vulgaris.
164. Nachbar M.S., and Oppenheim J.D. Lectins in the United States diet. A survey of lectins in commonly consumed foods and a review of the literature. American Journal of Clinical Nutrition 33 (1980) 2338-2345
165. Namba T. Phaseolin semen. A full-color illustrated book of Japanese flora (1980), Hoikusha, Tokyo
166. Nardini M., D'Aquino M., Tomassi G., Gentili V., Di-Felice M., and Scaccini C. Inhibition of human low-density lipoprotein oxidation by caffeic acid and other hydroxycinnamic acid derivatives. Free Radical Biology and Medicine 19 (1995) 541-552
167. National Research Council (1989). Recommended dietary allowances. Washington, DC: National Academy of Sciences.
168. Neilson F.H. Chromium. In: Shils M.E., Olson J.A., and Shike M. (Eds). Modern nutrition in health and disease. 8th ed. (1994), Philadelphia, Lea and Febiger 264-268
169. Nemets B., Fux M., Levine J., and Belmaker R.H. Combination of antidepressant drugs: The case of inositol. Human Psychopharmacology 16 (2001) 37-43
170. Nishino H., Murakoshi M., Masuda M., Tokuda H., Satomi Y., Onozuka M., et al. Suppression of lung and liver carcinogenesis in mice by oral administration of myo-inositol. Anticancer Research 19 (1999) 3663-3664
171. Oakenfull D., and Sidhu G.S. Saponins. In: Cheeke P. (Ed). Toxicants of Plant Origin (1989), CRC, Boca Raton, FL
172. Ogasawara H., Fujitani T., Drzewiecki G., and Middleton E. The role of hydrogen peroxide in basophil histamine release and the effect of selected flavonoids. Journal of Allergy and Clinical Immunology 78 (1986) 321-328
173. Oldani A., Ferini-Strambi L., Zucconi M., Stankov B., Fraschini F., and Smirne S. Melatonin and delayed sleep phase syndrome: Ambulatory polygraphic evaluation. Neuroreport 30 (1994) 132-134
174. Oomah B.D., Blanchard C., and Balasubramanian P. Phytic acid, phytase, minerals, and antioxidant activity in Canadian dry bean (Phaseolus vulgaris L.) cultivars. Journal of Agricultural and Food Chemistry 56 (2008) 11312-11319
175. Oomah B.D., Cardador-Martínez A., and Loarca-Piña G. Phenolics and antioxidative activities in common beans (Phaseolus vulgaris L.). Journal of the Science of Food and Agriculture 85 (2005) 935-942
176. Orcheson L.J., Rickard S.E., Seidl M.M., and Thompson L.U. Flaxseed and its mammalian lignan precursor cause a lengthening or cessation of estrous cycling in rats. Cancer Letters 125 (1998) 69-76
177. Ortega R.M. Dietary guidelines for pregnant women. Public Health Nutrition 4 (2001) 1343-1346
178. Page D., Aubert G., Duc G., Welham T., and Domoney C. Identification and exploitation of seed trypsin inhibitor gene polymorphism for molecular marker-assisted breeding and selection. Proceedings of the 4th European Conference on Grain Legumes, Cracow (2001), AEP Editions, Paris 20-21
179. Pandi-Perumal S.R., Zisapel N., Srinivasan V., and Cardinali D.P. Melatonin and sleep in an aging population. Experimental Gerontology 40 (2005) 911-925
180. Pappolla M.A., Chyan Y.J., Poeggeler B., Frangione B., Wilson G., and Ghiso J. An assessment of the antioxidant and antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease. Journal of Neural Transmission 107 (2000) 203-231
181. Petridou E., Ntouvelis E., Dessypris N., Terzidis A., and Trichopoulos D. Maternal diet and acute lymphoblastic leukemia in young children. Epidemiology Biomarkers and Prevention 14 (2005) 1935-1939
182. Phillippy B.Q. Inositol phosphates in food. Advances in Food and Nutrition Research 45 (2003) 1-60
183. Pieta P. Flavonoids as antioxidants. Journal of Natural Products 63 (2000) 1037-1042
184. Pittaway J.K., Ahuja K.D.K., Cehun M., Chronopoulos A., Robertson I.K., Nestel P.J., et al. Dietary supplementation with chickpeas for at least 5 weeks results in small but significant significant reductions in serum total and low-density lipoprotein cholesterols in adult woman and men. Annals of Nutrition and Metabolism 50 (2006) 512-518
185. Polat M., and Korkmaz M. An EPR study into the effect of annealing on both the Mn(II) and free radical signal in lentil. International Journal of Food Science and Technology 36 (2001) 313-320
186. Polkowski K., and Mazurek A.P. Biological properties of genistein. A review of in vitro and in vivo data. Acta Poloniae Pharmaceutica 57 (2000) 135-155
187. Price K.R., Johnson I.T., and Fenwick G.R. The chemistry and biological significance of saponins in food and feeding stuffs. Critical Review in Food Science and Nutrition 26 (1987) 27-135
188. Prodanov M., Sierra I., and Vidal-Valverde C. Effect of germination on the thiamine, riboflavin and niacin contents in legumes. Zeitschrift für Lebensmitteluntersuchung und -Forschung A 205 (1997) 48-52
189. Pruzanski W., and Vadas P. Phospholipase A2 - A mediator between proximal and distal effectors of inflammation. Immunology Today 12 (1991) 143-144
190. Pryme I.F., and Bardocz S. Anti-cancer therapy: Diversion of polyamines in the gut. European Journal of Gastroenterology and Hepatology 13 (2001) 1041-1046
191. Pusztai A. Characteristics and consequences of interactions of lectins with the intestinal mucosa. Archivos Latinoamericanos de Nutricion 44 (1996) 10S-15S
192. Pusztai A., Grant G., Buchan W.C., Bardocz S., De Carvalho A.F., and Ewen S.W. Lipid accumulation in obese Zucker rats is reduced by inclusion of raw kidney bean (Phaseolus vulgaris) in the diet. British Journal of Nutrition 79 (1998) 213-221
193. Pusztai A., Grant G., Duguid T., Brown D.S., Peumans W.J., Van Damme E.J., et al. Inhibition of starch digestion by α-amylase inhibitor reduces the efficiency of utilization of dietary proteins and lipids and retards the growth of rats. Journal of Nutrition 125 (1995) 1554-1562
194. Radberg K., Biernat M., Linderoth A., Zabielski R., Pierzynowski S.G., and Westrom B.R. Enteral exposure to crude red kidney bean lectin induces maturation of the gut in suckling pigs. Journal of Animal Science 79 (2001) 2669-2678
195. Ranilla, L. G., Genovese, M. I., & Lajolo, F. M. (2009). Isoflavones and antioxidant capacity of Peruvian and Brazilian lupin cultivars. Journal of Food Composition and Analysis, in press. doi:10.1016/j.jfca.2008.06.011.
196. Reiter R.J. The pineal and its hormones in the control of reproduction in mammals. Endocrinology Review 1 (1980) 109-131
197. Reiter R.J. Melatonin: The chemical expression of darkness. Molecular Cell Endocrinology 79 (1991) C153-C158
198. Reiter R.J. Potential biological consequences of excessive light exposure: Melatonin suppression, DNA damage, cancer and neurodegenerative diseases. Neuro Endocrinology Letters 23 (2002) 9-13
199. Remmelink M., Darro F., Decaestecker C., De Decker R., Bovin N.V., Gebhart M., et al. In vitro influence of lectins and neoglycoconjugates on the growth of three human sarcoma cell lines. Journal of Cancer Research and Clinical Oncology 125 (1999) 275-285
200. Reynoso-Camacho R., Gonzalez de Mejia E., and Loarca-Pina G. Purification and acute toxicity of a lectin extracted from tepary bean (Phaseolus acutifolius). Food and Chemical Toxicology 41 (2003) 21-27
201. Ricketts M.L., Moore D.D., Banz W.J., Mezei O., and Shay N.F. Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review. Journal of Nutritional Biochemistry 16 (2005) 321-330
202. Rimm E.B., Willett W.C., Hu F.B., Sampson L., Colditz G.A., Manson J.E., et al. Folate and Vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. Journal of the American Medical Association 279 (1998) 359-364
203. Rochfort S., and Panozzo J. Phytochemicals for health, the role of pulses. Journal of Agricultural and Food Chemistry 55 (2007) 7981-7994
204. Ruiz R.G., Price K.R., Arthur A.E., Rose M.E., Rhodes M.J.C., and Fenwick R.G. Effect of soaking and cooking on the saponin content and composition of chickpeas (Cicer arietinum) and lentils (Lens culinaris). Journal of Agricultural and Food Chemistry 44 (1996) 1526-1530
205. Ryan E., Galvin K., O'Connor T.P., Maguire A.R., and O'Brien N.M. Phytosterol, squalene, tocopherol content and fatty acid profile of selected seeds, grains, and legumes. Plant Foods for Human Nutrition 62 (2007) 85-91
206. Rycroft C.E., Jones M.R., Gibson G.R., and Rastall R.A. A comparative in vitro evaluation of the fermentation properties of prebiotic oligosaccharides. Journal of Applied Microbiology 91 (2001) 878-887
207. Salinas-Moreno Y., Rojas-Herrera L., Sosa-Montes E., and Pérez-Herrera P. Anthocyanin composition in black bean (Phaseolus vulgaris L.) varieties grown in México. Agrociencia 39 (2005) 385-394
208. Sames K., Schumacher U., Halata Z., Van Damme E.J., Peumans W.J., Asmus B., et al. Lectin and proteoglycan histochemistry of Merkel cell carcinomas. Experimental Dermatology 10 (2001) 100-109
209. Sanchez-Vioque R., Clemente A., Vioque J., Bautista J., and Millan F. Polar lipids of defatted chickpea (Cicer arietinum L.) flour and protein isolates. Food Chemistry 63 (1998) 357-361
210. Sandberg A.S. Bioavailability of minerals in legumes. British Journal of Nutrition 88 (2002) 281-285
211. Sarma B.K., Singh D.P., Mehta S., Singh H.B., and Singh U.P. Plant growth-promoting rhizobacteria-elicited alterations in phenolic profile of chickpea (Cicer arietinum) infected by Selerotium rolfsii. Journal of Phytopathology 150 (2002) 277-282
212. Sastry, C. S. T., & Kavathekar, K. Y. (1990). Plants for reclamation of wastelands (p. 684). New Delhi, India: Council of Scientific and Industrial Research.
213. Savage G.P., and Deo S. The nutritional value of peas (Pisum sativum). A literature review. Nutrition Abstracts and Reviews (Series A) 59 (1989) 66-83
214. Schwarz K., and Foltz C.M. Selenium as an integral part of factor 3 against dietary necrotic liver degeneration. Journal of the American Chemical Society 79 (1957) 3292-3293
215. Sgarbieri V.C., and Whitaker J.R. Physical, chemical, and nutritional properties of common bean (Phaseolus) proteins. Advances in Food Research 28 (1982) 93-166
216. Shamsuddin A.M. Metabolism and cellular functions of IP6: A review. Anticancer Research 19 (1999) 3733-3736
217. Shamsuddin A.M. Anti-cancer function of phytic acid. International Journal of Food Science and Technology 37 7 (2002) 769-782
218. Shamsuddin A.K.M., and Vucenik I. IP6 and inositol in cancer prevention and therapy. Current Cancer Therapy Reviews 1 (2005) 259-269
219. Sharma A., and Sehgal S. Effect of processing and cooking on the antinutritional factors of faba bean (Vicia faba). Food Chemistry 43 (1992) 383-385
220. Shi J., Arunasalam K., Yeung D., Kakuda Y., Mittal G., and Jiang Y. Saponins from edible legumes: Chemistry, processing, and health benefits. Journal of Medicinal Food 7 (2004) 67-78
221. Shils M.E., Olson J.A., Shike M., and Ross A.C. Modern nutrition in health and disease (1999), Williams & Wilkins, Baltimore, MD
222. Shils M.E., Olson J.A., and Shike M. Modern nutrition in health and disease (1994), Lea and Febiger, Philadelphia, PA
223. Shimura S., Itoh Y., Yamashita A., Gitano A., Hatano T., Yoshida T., et al. Inhibitory effects of flavonoids on lipase. Nippon Shokuhin kogyo Gakkaishi 41 (1994) 847-850
224. Singh U.P., Sarma B.K., and Singh D.P. Effect of plant growth promoting rhizobacteria and culture filtrate of Selerotium rolfsii on phenolic and salicylic acid contents in chickpea (Cicer arietinum). Current Microbiology 46 (2003) 131-140
225. Skene D.J., Lockley S.W., and Arendt J. Use of melatonin in treatment of phase shift and sleep disorders. Advances in Experimental Medicine and Biology 467 (1999) 79-84
226. Skinner D.C., and Malpaux B. High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Golen vein blood recirculating through the choroid plexus. Endocrinology 140 (1999) 4399-4405
227. Smulikowska S., Pastuszewska B., Swiech E., Ochtabinska A., Mieczkowska A., Nguyen V.C., et al. Tannin content affects negatively nutritive value of pea for monogastrics. Journal of Animal and Feed Sciences (Poland) 10 (2001) 511-523
228. Souci S.W., Fachmann W., and Kraut H. Food composition and nutrition tables. 5th ed. (1994), Medpharm Scientific Publications, CRC Press, Stuttgart
229. Spallholz J.E., Mallory Boylan L., and Rhaman M.M. Environmental hypothesis: Is poor dietary selenium intake an underlying factor for arsenicosis and cancer in Bangladesh and West Bengal, India?. Science of the Total Environment 323 (2004) 21-32
230. Steadman K.J., Burgoon M.S., Schuster R.L., Lewis B.A., Edwardson S.E., and Obendoff R.L. Fagopyritols, o-chiro-inositol, and other soluble carbohydrates in buckwheat seed milling fractions. Journal of Agricultural and Food Chemistry 48 (2000) 2843-2847
231. Steer T.E., and Gibson G.R. The microbiology of phytic acid metabolism by gut bacteria and relevance for bowel cancer. International Journal of Food Science and Technology 37 (2002) 783-790
232. Tang G.Y., Li X.J., and Zhang H.Y. Antidiabetic components contained in vegetables and legumes. Molecules 13 (2008) 1189-1194
233. Tao M.H., Xu W.H., Zheng W., Gao Y.T., Ruan Z.X., Cheng J.R., et al. A case-control study in Shanghai of fruit and vegetable intake and endometrial cancer. British Journal of Cancer 92 (2005) 2059-2064
234. Taylor, W. G., & Richards, K. W. (2008). Plant compositions enriched in dehydrosoyasaponin I (D-I) and methods of producing such compositions. World Patent WO 2008083461.
235. Terrés C., Navarro M., Martín-Lagos F., Giménez R., López H., and López M.C. Zinc levels in foods from southeastern Spain: Relationship to daily dietary intake. Food Additives and Contaminants 18 (2001) 687-695
236. Tharanathan R.N., and Mahadevamma S. Legumes - A boon to human nutrition. Trends in Food Science and Technology 14 (2003) 507-518
237. Thavarajah D., Ruszkowski J., and Vandenberg A. High potential for selenium biofortification of lentils (Lens culinaris L.). Journal of Agricultural and Food Chemistry 56 (2008) 10747-10753
238. Thewles A., Parslow R.A., and Coleman R. Effect of diosgenin on biliary cholesterol transport in the rat. Biochemical Journal 291 (1993) 793-798
239. Thompson G.R., and Grundy S.M. History and development of plant sterol and stanol esters for cholesterol-lowering purposes. American Journal of Cardiology 96 (2005) 3D-9D
240. Thomsson A., Rantzer D., Weström B.R., Pierzynowski S.G., and Svendsen J. Effects of crude red kidney bean lectin (phytohemagglutinin) exposure on performance, health, feeding behaviour, and gut maturation of pigs at weaning. Journal of Animal Science 85 (2007) 477-485
241. Trock B.J., Hilakivi-Clarke L., and Clarke R. Meta-analysis of soy intake and breast cancer risk. Journal of the National Cancer Institute 98 (2006) 459-471
242. USDA (2002). USDA-Iowa state university database on the isoflavone content of foods. Washington, DC: Agricultural Research Service, U.S. Department of Agriculture.
243. Vadivel V., and Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: An under-utilized food legume in South India. International Journal of Food Sciences and Nutrition 51 (2000) 279-287
244. Valdebouze P., Bergeron E., Gaborit T., and Delort-Laval J. Content and distribution of trypsin inhibitors and hemagglutinins in some legume seeds. Canadian Journal of Plant Science 60 (1980) 695-701
245. Velie E.M., Schairer C., Flood A., He J.-P., Khattree R., and Schatzkin A. Empirically derived dietary patterns and risk of postmenopausal breast cancer in a large prospective cohort study. American Journal of Clinical Nutrition 82 (2005) 1308-1319
246. Venn B.J., and Mann J.I. Cereal grains, legumes and diabetes. European Journal of Clinical Nutrition 58 (2004) 1443-1461
247. Vidal-Valverde C., Sierra I., Diaz-Pollan C., and Blazquez I. Determination by capillary electrophoresis of total and available niacin in different development stage of raw and processed legumes: Comparison with high-performance liquid chromatography. Electrophoresis 22 (2001) 1479-1484
248. Villegas R., Gao Y.T., Yang G., Li H.L., Elasy T.A., Zheng W., et al. Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study. American Journal of Clinical Nutrition 87 (2008) 162-167
249. Viroben G. Substances indesirables pour le monogastrique [substances toxiques et nocives]. Le Sélectionneur-Français 27 (1979) 21-25
250. Vucenik I., and Shamsuddin A.M. Protection against cancer by dietary IP6 and inositol. Nutrition and Cancer 55 (2006) 109-125
251. Wald D.S., Law M., and Morris J.K. Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis. British Medical Journal 325 (2002) 1202-1208
252. Walker A.F., and Ochhar N. Effect of processing including domestic cooking on nutritional quality of legumes. Proceedings of the Nutrition Society 41 (1982) 41-51
253. Wang H., Ng T.B., Ooi V.E., and Liu W.K. Effects of lectins with different carbohydrate-binding specificities on hepatoma, choriocarcinoma, melanoma and osteosarcoma cell lines. International Journal of Biochemistry and Cell Biology 32 (2000) 365-372
254. Wang S.Y., Wu J.H., Ng T.B., Ye X.Y., and Rao P.F. A non-specific lipid transfer protein with antifungal and antibacterial activities from the mung bean. Peptides 25 (2004) 1235-1242
255. Warrier P.K.W., Nambiar V.P.K., and Remankutty C. Indian medicinal plants (1995), Orient Longman, Chennai, India
256. Wattenberg L.W., Wiedmann T.S., Estensen R.D., Zimmerman C.L., Galbraith A.R., Steele V.E., et al. Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol. Carcinogenesis 21 (2000) 179-182
257. Weaver C.M., and Kannan S. Phytate and mineral bioavailability. In: Sathe, and Reddy S.K. (Eds). Food phytates (2002), CRC, Boca Raton 211-224
258. Weihrauch J.L., and Gardner J.M. Sterol content of foods of plant origin. Journal of the American Dietetic Association 73 (1978) 39-44
259. Welch R.M., and Graham R.D. Breeding for micronutrients in staple food crops from a human nutrition perspective. Journal of Experimental Botany 55 (2004) 353-364
260. Williams D.E., Prevost A.T., Whichelow M.J., Cox B.D., Day N.E., and Wareham N.J. A cross-sectional study of dietary patterns with glucose intolerance and other features of the metabolic syndrome. British Journal of Nutrition 83 (2000) 257-266
261. Woldemichael G.M., Montenegro G., and Timmermann B.N. Triterpenoidal lupin saponins from the Chilean legume Lupinus oreophilus Phil. Phytochemistry 63 (2003) 853-857
262. Wu C., and Whitaker J.R. Homology among trypsin/chymotrypsin inhibitors from red kidney bean, Brazilian pink bean, lima bean, and soybean. Journal of Agricultural and Food Chemistry 39 (1991) 1583-1589
263. Xiao J.X., Huang G.Q., Zhu C.P., Ren D.D., and Zhang S.H. Morphological study on apoptosis HeLa cells induced by soyasaponins. Toxicology in Vitro 21 (2007) 820-826
264. Xing N., Chen Y., Mitchell S.H., and Young Y.F.C. Quercetin inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells. Carcinogenesis 22 (2001) 409-414
265. Xu B.J., and Chang S.K.C. A comparative study on phenolic profiles and antioxidant activities of legumes as affected by extraction solvents. Journal of Food Science 72 (2007) S159-S166
266. Xu B.S., and Chang K.C. Effect of soaking, boiling, and steaming on total phenolic content and antioxidant activities of cool season food legumes. Food Chemistry 110 (2008) 1-13
267. Yeh C.T., and Yen G.C. Effects of phenolic acids on human phenolsulfotransferases in relation to their antioxidant activity. Journal of Agricultural and Food Chemistry 51 (2003) 1474-1479
268. Yoshida H., Tomiyama Y., Yoshida N., Saiki M., and Mizushina Y. Lipid classes, fatty acid compositions and triacylglycerol molecular species from adzuki beans (Vigna angularis). Journal of Food Lipids 15 (2008) 343-355
269. Zdunczyk Z., Godycka I., and Amarowicz R. Chemical composition and content of antinutritional factors in Polish cultivars of peas. Plant Foods for Human Nutrition 50 (1997) 37-45
270. Zhang J., Shi J., Ilic S., Jun X.S., and Kakuda Y. Biological properties and characterization of lectin from red kidney bean (Phaseolus vulgaris). Food Reviews International 25 (2009) 12-27
271. Zhou J.R., and Erdman Jr. J.W. Phytic acid in health and disease. Critical Reviews in Food Science and Nutrition 35 (1995) 495-508
272. Zhu J., Xiong L., Yu B., and Wu J. Apoptosis induced by a new member of saponin family is mediated through caspase-8-dependent cleavage of Bcl-2. Molecular Pharmacology 68 (2005) 1831-1838
273. Zia-Ul-Haq M., Iqbal S., Ahmad S., Bhanger M.I., Wiczkowsi W., and Amarowicz R. Antioxidant potential of desi chickpea varieties commonly consumed in Pakistan. Journal of Food Lipids 15 (2008) 326-342
274. Zielínski, H., Lewczuk, B., Przybylska-Gornowicz, B., & Kozowska, H. (2001). Melatonin in germinated legume seeds as a potentially significant agent for health. In W. Pfanhauser, G. R. Fenwick, & S. Khokhar (Eds.), Biologically-active phytochemicals in food: Analysis, metabolism, bioavailability and function (pp. 26-28). Proceedings of the EUROFOODCHEM XI, Norwich, UK.