메뉴 건너뛰기




Volumn 16, Issue 6, 2005, Pages 321-330

Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review

Author keywords

Cholesterol; Isoflavone; Nuclear hormone receptors; Soy

Indexed keywords

CELL NUCLEUS RECEPTOR; CLOFIBRATE; DAIDZEIN; DEXAMETHASONE; EQUOL; ESTROGEN RECEPTOR; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GENISTEIN; GLYCITEIN; HORMONE RECEPTOR; ISOFLAVONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PREGNENOLONE; ROSIGLITAZONE; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

EID: 20144375350     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2004.11.008     Document Type: Review
Times cited : (140)

References (66)
  • 1
    • 0029056306 scopus 로고
    • Meta-analysis of the effects of soy protein intake on serum lipids
    • J.W. Anderson, B.M. Johnstone, and M.E. Cook-Newell Meta-analysis of the effects of soy protein intake on serum lipids N. Engl. J. Med. 333 1995 276 282
    • (1995) N. Engl. J. Med. , vol.333 , pp. 276-282
    • Anderson, J.W.1    Johnstone, B.M.2    Cook-Newell, M.E.3
  • 3
    • 0031665212 scopus 로고    scopus 로고
    • Soy protein, isoflavones and cardiovascular disease risk
    • A.H. Lichtenstein Soy protein, isoflavones and cardiovascular disease risk J. Nutr. 128 1998 1589 1592
    • (1998) J. Nutr. , vol.128 , pp. 1589-1592
    • Lichtenstein, A.H.1
  • 4
    • 0033997227 scopus 로고    scopus 로고
    • Soy and cardiovascular disease: Cholesterol lowering and beyond
    • M.S. Anthony Soy and cardiovascular disease: cholesterol lowering and beyond J. Nutr. 130 2000 662S 663S
    • (2000) J. Nutr. , vol.130
    • Anthony, M.S.1
  • 5
    • 0036898114 scopus 로고    scopus 로고
    • The clinical importance of the metabolite equol - A clue to the effectiveness of soy and its isoflavones
    • K.D. Setchell, N.M. Brown, and E. Lydeking-Olsen The clinical importance of the metabolite equol - a clue to the effectiveness of soy and its isoflavones J. Nutr. 132 12 2002 3577 3584
    • (2002) J. Nutr. , vol.132 , Issue.12 , pp. 3577-3584
    • Setchell, K.D.1    Brown, N.M.2    Lydeking-Olsen, E.3
  • 6
    • 0016517722 scopus 로고
    • Hormone studies on ewes grazing an oestrogenic (Yarloop clover) pasture during the reproductive cycle
    • J.M. Obst, and R.F. Seamark Hormone studies on ewes grazing an oestrogenic (Yarloop clover) pasture during the reproductive cycle Aust. J. Biol. Sci. 28 3 1975 279 290
    • (1975) Aust. J. Biol. Sci. , vol.28 , Issue.3 , pp. 279-290
    • Obst, J.M.1    Seamark, R.F.2
  • 7
    • 0033929211 scopus 로고    scopus 로고
    • Isoflavone aglycone-rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits
    • J. Yamakoshi, M.K. Piskula, T. Izumi, K. Tobe, M. Saito, and S. Kataoka Isoflavone aglycone-rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits J. Nutr. 130 2000 1887 1893
    • (2000) J. Nutr. , vol.130 , pp. 1887-1893
    • Yamakoshi, J.1    Piskula, M.K.2    Izumi, T.3    Tobe, K.4    Saito, M.5    Kataoka, S.6
  • 8
    • 0033850693 scopus 로고    scopus 로고
    • A cooperative interaction between soy protein and its isoflavone-enriched fraction lowers hepatic lipids in male obese Zucker rats and reduces blood platelet sensitivity in male Sprague-Dawley rats
    • M.R. Peluso, T.A. Winters, M.F. Shanahan, and W.J. Banz A cooperative interaction between soy protein and its isoflavone-enriched fraction lowers hepatic lipids in male obese Zucker rats and reduces blood platelet sensitivity in male Sprague-Dawley rats J. Nutr. 130 2000 2333 2342
    • (2000) J. Nutr. , vol.130 , pp. 2333-2342
    • Peluso, M.R.1    Winters, T.A.2    Shanahan, M.F.3    Banz, W.J.4
  • 9
    • 0036713363 scopus 로고    scopus 로고
    • Hepatic cytochrome P450-2A and phosphoribosylpyrophosphate synthetase-associated protein mRNAs are induced in the gerbil after consumption of isoflavone containing protein
    • O. Mezei, C.N. Chou, K.J. Kennedy, C. Tovar-Palacio, and N.F. Shay Hepatic cytochrome P450-2A and phosphoribosylpyrophosphate synthetase-associated protein mRNAs are induced in the gerbil after consumption of isoflavone containing protein J. Nutr. 132 2002 2538 2544
    • (2002) J. Nutr. , vol.132 , pp. 2538-2544
    • Mezei, O.1    Chou, C.N.2    Kennedy, K.J.3    Tovar-Palacio, C.4    Shay, N.F.5
  • 10
    • 0031685359 scopus 로고    scopus 로고
    • Long-term intake of soy protein lowers the risk of cardiovascular disease in postmenopausal women with high cholesterol
    • J. Baum, H. Teng, J.W. Erdman, B.P. Klein, V.W. Persky, and S. Freels Long-term intake of soy protein lowers the risk of cardiovascular disease in postmenopausal women with high cholesterol Am. J. Clin. Nutr. 68 1998 545 561
    • (1998) Am. J. Clin. Nutr. , vol.68 , pp. 545-561
    • Baum, J.1    Teng, H.2    Erdman, J.W.3    Klein, B.P.4    Persky, V.W.5    Freels, S.6
  • 11
    • 0031814876 scopus 로고    scopus 로고
    • Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice
    • E.A. Kirk, P. Sutherland, S.A. Wang, A. Chait, and R.C. LeBoeuf Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice J. Nutr. 128 6 1998 954 959
    • (1998) J. Nutr. , vol.128 , Issue.6 , pp. 954-959
    • Kirk, E.A.1    Sutherland, P.2    Wang, S.A.3    Chait, A.4    Leboeuf, R.C.5
  • 12
    • 0036847363 scopus 로고    scopus 로고
    • The atheroprotective effect of dietary soy isoflavones in apolipoprotein E-/- mice requires the presence of estrogen receptor-alpha
    • M.R. Adams, D.L. Golden, T.C. Register, M.S. Anthony, J.B. Hodgin, and N. Maeda The atheroprotective effect of dietary soy isoflavones in apolipoprotein E-/- mice requires the presence of estrogen receptor-alpha Arterioscler. Thromb. Vasc. Biol. 22 11 2002 1859 1864
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , Issue.11 , pp. 1859-1864
    • Adams, M.R.1    Golden, D.L.2    Register, T.C.3    Anthony, M.S.4    Hodgin, J.B.5    Maeda, N.6
  • 13
    • 0036140126 scopus 로고    scopus 로고
    • The inhibitory effect of soy protein isolate on atherosclerosis in mice does not require the presence of LDL receptors or alteration of plasma lipoproteins
    • M.R. Adams, D.L. Golden, M.S. Anthony, T.C. Register, and J.K. Williams The inhibitory effect of soy protein isolate on atherosclerosis in mice does not require the presence of LDL receptors or alteration of plasma lipoproteins J. Nutr. 132 1 2002 43 49
    • (2002) J. Nutr. , vol.132 , Issue.1 , pp. 43-49
    • Adams, M.R.1    Golden, D.L.2    Anthony, M.S.3    Register, T.C.4    Williams, J.K.5
  • 15
    • 0036895683 scopus 로고    scopus 로고
    • Beneficial role of dietary phytoestrogens in obesity and diabetes
    • S.J. Bhathena, and M.T. Velasquez Beneficial role of dietary phytoestrogens in obesity and diabetes Am. J. Clin. Nutr. 76 6 2002 1191 1201
    • (2002) Am. J. Clin. Nutr. , vol.76 , Issue.6 , pp. 1191-1201
    • Bhathena, S.J.1    Velasquez, M.T.2
  • 17
    • 0031771536 scopus 로고    scopus 로고
    • Effects of soy protein on renal function and proteinuria in patients with type 2 diabetes
    • J.W. Anderson, J.E. Blake, J. Turner, and B.M. Smith Effects of soy protein on renal function and proteinuria in patients with type 2 diabetes Am. J. Clin. Nutr. 68 1998 1347S 1353S
    • (1998) Am. J. Clin. Nutr. , vol.68
    • Anderson, J.W.1    Blake, J.E.2    Turner, J.3    Smith, B.M.4
  • 18
    • 0038659583 scopus 로고    scopus 로고
    • The use of the combined food products with soy protein in diet therapy for patients with diabetes mellitus type 2
    • V.A. Meshcheriakova, O.A. Plotnikova, K. Sharafetdinov, and T.A. Iatsyshina The use of the combined food products with soy protein in diet therapy for patients with diabetes mellitus type 2 Vopr. Pitan. 71 2002 19 24
    • (2002) Vopr. Pitan. , vol.71 , pp. 19-24
    • Meshcheriakova, V.A.1    Plotnikova, O.A.2    Sharafetdinov, K.3    Iatsyshina, T.A.4
  • 19
    • 0036076781 scopus 로고    scopus 로고
    • Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women
    • D.J. Jenkins, C.W. Kendall, C.J. Jackson, P.W. Connelly, T. Parker, and D. Faulkner Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women Am. J. Clin. Nutr. 76 2002 365 372
    • (2002) Am. J. Clin. Nutr. , vol.76 , pp. 365-372
    • Jenkins, D.J.1    Kendall, C.W.2    Jackson, C.J.3    Connelly, P.W.4    Parker, T.5    Faulkner, D.6
  • 20
    • 0036673636 scopus 로고    scopus 로고
    • Animal versus plant protein meals in individuals with type 2 diabetes and microalbuminuria: Effects on renal, glycemic, and lipid parameters
    • M.L. Wheeler, S.E. Fineberg, N.S. Fineberg, R.G. Gibson, and L.L. Hackward Animal versus plant protein meals in individuals with type 2 diabetes and microalbuminuria: effects on renal, glycemic, and lipid parameters Diabetes Care 25 2002 1277 1282
    • (2002) Diabetes Care , vol.25 , pp. 1277-1282
    • Wheeler, M.L.1    Fineberg, S.E.2    Fineberg, N.S.3    Gibson, R.G.4    Hackward, L.L.5
  • 21
    • 0035146283 scopus 로고    scopus 로고
    • Beneficial effects of a soy-based dietary supplement on lipid levels and cardiovascular risk markers in type 2 diabetic subjects
    • K. Hermansen, M. Sondergaard, L. Hoie, M. Carstensen, and B. Brock Beneficial effects of a soy-based dietary supplement on lipid levels and cardiovascular risk markers in type 2 diabetic subjects Diabetes Care 24 2001 228 233
    • (2001) Diabetes Care , vol.24 , pp. 228-233
    • Hermansen, K.1    Sondergaard, M.2    Hoie, L.3    Carstensen, M.4    Brock, B.5
  • 22
    • 0034284918 scopus 로고    scopus 로고
    • Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
    • J.J. Repa, S.D. Turley, J.A. Lobaccaro, J. Medina, L. Li, and K. Lustig Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers Science 289 5484 2000 1524 1529
    • (2000) Science , vol.289 , Issue.5484 , pp. 1524-1529
    • Repa, J.J.1    Turley, S.D.2    Lobaccaro, J.A.3    Medina, J.4    Li, L.5    Lustig, K.6
  • 23
    • 0036040929 scopus 로고    scopus 로고
    • Effects of fibrates on serum metabolic parameters
    • M. Elisaf Effects of fibrates on serum metabolic parameters Curr. Med. Res. Opin. 18 5 2002 269 276
    • (2002) Curr. Med. Res. Opin. , vol.18 , Issue.5 , pp. 269-276
    • Elisaf, M.1
  • 25
    • 0030771389 scopus 로고    scopus 로고
    • Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha
    • P. Pace, J. Taylor, S. Suntharalingam, R.C. Coombes, and S. Ali Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha J. Biol. Chem. 272 41 1997 25832 25838
    • (1997) J. Biol. Chem. , vol.272 , Issue.41 , pp. 25832-25838
    • Pace, P.1    Taylor, J.2    Suntharalingam, S.3    Coombes, R.C.4    Ali, S.5
  • 26
    • 0346849610 scopus 로고    scopus 로고
    • Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element
    • D. Kostelac, G. Rechkemmer, and K. Briviba Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element J. Agric. Food Chem. 51 26 2003 7632 7635
    • (2003) J. Agric. Food Chem. , vol.51 , Issue.26 , pp. 7632-7635
    • Kostelac, D.1    Rechkemmer, G.2    Briviba, K.3
  • 28
    • 0032752637 scopus 로고    scopus 로고
    • Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro
    • M. Casanova, L. You, K.W. Gaido, S. Archibeque-Engle, D.B. Janszen, and H.A. Heck Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro Toxicol. Sci. 51 2 1999 236 244
    • (1999) Toxicol. Sci. , vol.51 , Issue.2 , pp. 236-244
    • Casanova, M.1    You, L.2    Gaido, K.W.3    Archibeque-Engle, S.4    Janszen, D.B.5    Heck, H.A.6
  • 29
    • 0021235849 scopus 로고
    • Soya - A dietary source of the non-steroidal oestrogen equol in man and animals
    • M. Axelson, J. Sjovall, B.E. Gustafsson, and K.D. Setchell Soya - a dietary source of the non-steroidal oestrogen equol in man and animals J. Endocrinol. 102 1 1984 49 56
    • (1984) J. Endocrinol. , vol.102 , Issue.1 , pp. 49-56
    • Axelson, M.1    Sjovall, J.2    Gustafsson, B.E.3    Setchell, K.D.4
  • 30
    • 1542376914 scopus 로고    scopus 로고
    • In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production
    • C. Atkinson, S. Berman, O. Humbert, and J.W. Lampe In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production J. Nutr. 134 3 2004 596 599
    • (2004) J. Nutr. , vol.134 , Issue.3 , pp. 596-599
    • Atkinson, C.1    Berman, S.2    Humbert, O.3    Lampe, J.W.4
  • 31
    • 0037766468 scopus 로고    scopus 로고
    • Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals
    • F. Rafii, C. Davis, M. Park, T.M. Heinze, and R.D. Beger Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals Arch. Microbiol. 180 1 2003 11 16
    • (2003) Arch. Microbiol. , vol.180 , Issue.1 , pp. 11-16
    • Rafii, F.1    Davis, C.2    Park, M.3    Heinze, T.M.4    Beger, R.D.5
  • 33
    • 0037205046 scopus 로고    scopus 로고
    • A natural product that lowers cholesterol as an antagonist ligand for FXR
    • N.L. Urizar, A.B. Liverman, D.T. Dodds, F.V. Silva, P. Ordentlich, and Y. Yan A natural product that lowers cholesterol as an antagonist ligand for FXR Science 296 5573 2002 1703 1706
    • (2002) Science , vol.296 , Issue.5573 , pp. 1703-1706
    • Urizar, N.L.1    Liverman, A.B.2    Dodds, D.T.3    Silva, F.V.4    Ordentlich, P.5    Yan, Y.6
  • 35
    • 0036134747 scopus 로고    scopus 로고
    • Effect of soy protein on endogenous hormones in postmenopausal women
    • V.W. Persky, M.E. Turyk, L. Wang, S. Freels, R. Chatterton Jr., and S. Barnes Effect of soy protein on endogenous hormones in postmenopausal women Am. J. Clin. Nutr. 75 1 2002 145 153 [erratum in: Am J Clin Nutr 2002 Sep;76(3):695]
    • (2002) Am. J. Clin. Nutr. , vol.75 , Issue.1 , pp. 145-153
    • Persky, V.W.1    Turyk, M.E.2    Wang, L.3    Freels, S.4    Chatterton Jr., R.5    Barnes, S.6
  • 36
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
    • L. Nagy, P. Tontonoz, J.G.A. Alvarez, H. Chen, and R.M. Evans Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ Cell 93 1998 229 240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.A.3    Chen, H.4    Evans, R.M.5
  • 37
    • 0035138625 scopus 로고    scopus 로고
    • PPARα and PPARγ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • G. Chinetti, S. Lestavel, V. Bocher, A.T. Remaley, B. Neve, and I.P. Torra PPARα and PPARγ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway Nat. Med. 2001 53 58
    • (2001) Nat. Med. , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3    Remaley, A.T.4    Neve, B.5    Torra, I.P.6
  • 38
    • 0033867274 scopus 로고    scopus 로고
    • Evidence for peroxisome proliferator-activated receptor (PPAR)alpha-independent peroxisome proliferation: Effects of PPARgamma/delta-specific agonists in PPARalpha-null mice
    • J.G. DeLuca, T.W. Doebber, L.J. Kelly, R.K. Kemp, S. Molon-Noblot, and S.P. Sahoo Evidence for peroxisome proliferator-activated receptor (PPAR)alpha-independent peroxisome proliferation: effects of PPARgamma/delta-specific agonists in PPARalpha-null mice Mol. Pharmacol. 58 3 2000 470 476
    • (2000) Mol. Pharmacol. , vol.58 , Issue.3 , pp. 470-476
    • Deluca, J.G.1    Doebber, T.W.2    Kelly, L.J.3    Kemp, R.K.4    Molon-Noblot, S.5    Sahoo, S.P.6
  • 39
    • 0033864582 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
    • A.C. Li, K.K. Brown, M.J. Silvestre, T.M. Willson, W. Palinski, and C.K. Glass Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice J. Clin. Invest. 106 4 2000 523 531
    • (2000) J. Clin. Invest. , vol.106 , Issue.4 , pp. 523-531
    • Li, A.C.1    Brown, K.K.2    Silvestre, M.J.3    Willson, T.M.4    Palinski, W.5    Glass, C.K.6
  • 40
    • 0036205326 scopus 로고    scopus 로고
    • Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux
    • T.E. Akiyama, S. Sakai, G. Lambert, C.J. Nicol, K. Matsusue, and S. Pimprale Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux Mol. Cell. Biol. 22 8 2002 2607 2619
    • (2002) Mol. Cell. Biol. , vol.22 , Issue.8 , pp. 2607-2619
    • Akiyama, T.E.1    Sakai, S.2    Lambert, G.3    Nicol, C.J.4    Matsusue, K.5    Pimprale, S.6
  • 41
    • 0141446024 scopus 로고    scopus 로고
    • Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
    • O. Gavrilova, M. Haluzik, K. Matsusue, J.J. Cutson, L. Johnson, and K.R. Dietz Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass J. Biol. Chem. 278 36 2003 34268 34276
    • (2003) J. Biol. Chem. , vol.278 , Issue.36 , pp. 34268-34276
    • Gavrilova, O.1    Haluzik, M.2    Matsusue, K.3    Cutson, J.J.4    Johnson, L.5    Dietz, K.R.6
  • 42
    • 0038353634 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis
    • H. Kim, M. Haluzik, Z. Asghar, D. Yau, J.W. Joseph, and A.M. Fernandez Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis Diabetes 52 7 2003 1770 1778
    • (2003) Diabetes , vol.52 , Issue.7 , pp. 1770-1778
    • Kim, H.1    Haluzik, M.2    Asghar, Z.3    Yau, D.4    Joseph, J.W.5    Fernandez, A.M.6
  • 43
    • 0037015026 scopus 로고    scopus 로고
    • PPAR alpha is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue
    • Y. Lee, X. Yu, F. Gonzales, D.J. Mangelsdorf, M.Y. Wang, and C. Richardson PPAR alpha is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue Proc. Natl. Acad. Sci. U. S. A. 99 18 2002 11848 11853
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , Issue.18 , pp. 11848-11853
    • Lee, Y.1    Yu, X.2    Gonzales, F.3    Mangelsdorf, D.J.4    Wang, M.Y.5    Richardson, C.6
  • 46
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
    • Y.X. Wang, C.H. Lee, S. Tiep, R.T. Yu, J. Ham, and H. Kang Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity Cell 113 2 2003 159 170
    • (2003) Cell , vol.113 , Issue.2 , pp. 159-170
    • Wang, Y.X.1    Lee, C.H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5    Kang, H.6
  • 48
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • G. Chinetti, J.-C. Fruchart, and B. Staels Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation Inflamm. Res. 49 2000 497 505
    • (2000) Inflamm. Res. , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.-C.2    Staels, B.3
  • 49
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • A. Chawla, Y. Barak, L. Nagy, D. Liao, P. Tontonoz, and R.M. Evans PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation Nat. Med. 7 1 2001 48 52
    • (2001) Nat. Med. , vol.7 , Issue.1 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 50
    • 0034520463 scopus 로고    scopus 로고
    • Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat
    • S.A. Smith, C.A. Lister, C.D. Toseland, and R.E. Buckingham Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat Diabetes Obes. Metab. 2 2000 363 372
    • (2000) Diabetes Obes. Metab. , vol.2 , pp. 363-372
    • Smith, S.A.1    Lister, C.A.2    Toseland, C.D.3    Buckingham, R.E.4
  • 51
    • 0037657668 scopus 로고    scopus 로고
    • Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells
    • O. Mezei, W.J. Banz, R.W. Steger, M.R. Peluso, T.A. Winters, and N. Shay Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells J. Nutr. 133 2003 1238 1243
    • (2003) J. Nutr. , vol.133 , pp. 1238-1243
    • Mezei, O.1    Banz, W.J.2    Steger, R.W.3    Peluso, M.R.4    Winters, T.A.5    Shay, N.6
  • 53
  • 54
    • 0031936521 scopus 로고    scopus 로고
    • Evolution of the health benefits of soy isoflavones
    • S. Barnes Evolution of the health benefits of soy isoflavones Proc. Soc. Exp. Biol. Med. 217 3 1998 386 392
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , Issue.3 , pp. 386-392
    • Barnes, S.1
  • 55
    • 0030976331 scopus 로고    scopus 로고
    • Phyto-oestrogens and Western diseases
    • H. Adlercreutz, and W. Mazur Phyto-oestrogens and Western diseases Ann. Med. 29 2 1997 95 120
    • (1997) Ann. Med. , vol.29 , Issue.2 , pp. 95-120
    • Adlercreutz, H.1    Mazur, W.2
  • 56
    • 0031741906 scopus 로고    scopus 로고
    • Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones
    • K.D. Setchell Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones Am. J. Clin. Nutr. 68 6 Suppl 1998 1333S 1346S
    • (1998) Am. J. Clin. Nutr. , vol.68 , Issue.6 SUPPL.
    • Setchell, K.D.1
  • 57
    • 0037015917 scopus 로고    scopus 로고
    • Differentially abundant mRNAs in rat liver in response to diets containing soy protein isolate
    • M.J. Iqbal, S. Yaegashi, R. Ahsan, D.A. Lightfoot, and W.J. Banz Differentially abundant mRNAs in rat liver in response to diets containing soy protein isolate Physiol. Genomics 11 2002 219 226
    • (2002) Physiol. Genomics , vol.11 , pp. 219-226
    • Iqbal, M.J.1    Yaegashi, S.2    Ahsan, R.3    Lightfoot, D.A.4    Banz, W.J.5
  • 58
    • 20144371104 scopus 로고    scopus 로고
    • Soy diets regulate adiposity, insulin sensitivity and lipogenic capacity in male ZDF rats
    • W.J. Banz, N. Moustaind-Moussa, A. Tebbe, Y.-C. Kim, K.W. Cho, and N.F. Shay Soy diets regulate adiposity, insulin sensitivity and lipogenic capacity in male ZDF rats FASEB J. 2004 [(abs) 369.3.]
    • (2004) FASEB J.
    • Banz, W.J.1    Moustaind-Moussa, N.2    Tebbe, A.3    Kim, Y.-C.4    Cho, K.W.5    Shay, N.F.6
  • 59
    • 0344011490 scopus 로고    scopus 로고
    • Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors
    • M. Suetsugi, L. Su, K. Karlsberg, Y.C. Yuan, and S. Chen Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors Mol. Cancer Res. 1 13 2003 981 991
    • (2003) Mol. Cancer Res. , vol.1 , Issue.13 , pp. 981-991
    • Suetsugi, M.1    Su, L.2    Karlsberg, K.3    Yuan, Y.C.4    Chen, S.5
  • 60
    • 0032526489 scopus 로고    scopus 로고
    • Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41
    • J.D. Eudy, S. Yao, M.D. Weston, M. Ma-Edmonds, C.B. Talmadge, and J.J. Cheng Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41 Genomics 50 3 1998 382 384
    • (1998) Genomics , vol.50 , Issue.3 , pp. 382-384
    • Eudy, J.D.1    Yao, S.2    Weston, M.D.3    Ma-Edmonds, M.4    Talmadge, C.B.5    Cheng, J.J.6
  • 61
    • 0033529498 scopus 로고    scopus 로고
    • Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3
    • H. Hong, L. Yang, and M.R. Stallcup Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3 J. Biol. Chem. 274 32 1999 22618 22626
    • (1999) J. Biol. Chem. , vol.274 , Issue.32 , pp. 22618-22626
    • Hong, H.1    Yang, L.2    Stallcup, M.R.3
  • 62
    • 0029965083 scopus 로고    scopus 로고
    • Estrogen-related receptor, hER1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter
    • N. Yang, H. Shigeta, H. Shi, and C.T. Teng Estrogen-related receptor, hER1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter J. Biol. Chem. 271 1996 5795 5804
    • (1996) J. Biol. Chem. , vol.271 , pp. 5795-5804
    • Yang, N.1    Shigeta, H.2    Shi, H.3    Teng, C.T.4
  • 63
    • 0030787844 scopus 로고    scopus 로고
    • The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme a dehydrogenase gene
    • R. Sladek, J.A. Bader, and V. Giguere The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme a dehydrogenase gene Mol. Cell. Biol. 17 9 1997 5400 5409
    • (1997) Mol. Cell. Biol. , vol.17 , Issue.9 , pp. 5400-5409
    • Sladek, R.1    Bader, J.A.2    Giguere, V.3
  • 64
    • 0031468588 scopus 로고    scopus 로고
    • A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation
    • R.B. Vega, and D.P. Kelly A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation J. Biol. Chem. 272 50 1997 31693 31699
    • (1997) J. Biol. Chem. , vol.272 , Issue.50 , pp. 31693-31699
    • Vega, R.B.1    Kelly, D.P.2
  • 66


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.