Inhibitors and modulators of β- and γ-secretase

Current Topics in Medicinal Chemistry

Volumn 6, Issue 4, 2006, Pages 377-392

  Schmidt, Boris ^a   Baumann, Stefanie ^a   Braun, Hannes A ^a   Larbig, Gregor ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Alzheimer's disease; Aspartic protease; Inhibitor; Presenilin; Secretase

Indexed keywords

2 IMINOIMIDAZOLIDIN 4 ONE DERIVATIVE; ALPHA TOCOPHEROL; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE INHIBITOR; CATHEPSIN D; CHOLINERGIC RECEPTOR STIMULATING AGENT; CHOLINESTERASE INHIBITOR; DONEPEZIL; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; L 685 458; L 852 505; L 852 646; LY 411575; LY 450139; MEVINOLIN; MUSCARINIC M1 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; OM 00 3; OM 99 2; PHOSPHODIESTERASE IV; PLACEBO; PRAVASTATIN; PROTEINASE INHIBITOR; SEROTONIN AGONIST; TETRAMIC ACID DERIVATIVE; TETRONIC ACID DERIVATIVE; TIPRANAVIR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; CLINICAL TRIAL; DRUG APPROVAL; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; GENE MUTATION; GENE TARGETING; HUMAN; NONHUMAN; PROTEIN METABOLISM; PROTEIN PROCESSING; REVIEW; STRUCTURE ANALYSIS;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELL LINE; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR;

EID: 33646121776     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802606776287027     Document Type: Review

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