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Journal of Biological Chemistry

Volumn 277, Issue 7, 2002, Pages 4687-4693

Substrate and inhibitor profile of BACE (β-secretase) and comparison with other mammalian aspartic proteases

(5) Grüninger Leitch, Fiona a Schlatter, Daniel a Küng, Erich a Nelböck, Peter a Döbeli, Heinz a

a F HOFFMANN LA ROCHE LTD (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CLONING; DISEASES; ENZYMES; HYDROPHOBICITY; PATHOLOGY; SUBSTRATES;

PATHOGENESIS;

BIOCHEMISTRY;

AMINO ACID; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BETA SECRETASE; CATHEPSIN D; CATHEPSIN E; ENZYME INHIBITOR; LEUCINE; PEPSIN A; RENIN;

ACIDITY; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HYDROPHOBICITY; MAMMAL; MOLECULAR CLONING; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CATHEPSIN D; CATHEPSIN E; CELL LINE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENDOPEPTIDASES; HUMANS; HYDROGEN-ION CONCENTRATION; INSECTS; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; PEPSIN A; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

ANIMALIA; MAMMALIA;

EID: 0037085353 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M109266200 Document Type: Article

Times cited : (228)

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