SCOPUS 정보 검색 플랫폼

Volumn 44, Issue 18, 2001, Pages 2865-2868

Structure-based design: Potent inhibitors of human brain memapsin 2 (β-secretase)

(12) Ghosh, A K a Bilcer, G a Harwood, C a Kawahama, R a,b Shin, D a Hussain, K A a,b Hong, L c Loy, J A c Nguyen, C c Koelsch, G c Ermolieff, J c Tang, J c,d

a UNIVERSITY OF ILLINOIS AT CHICAGO (United States)

b Zapaq Inc (United States)

c OKLAHOMA MEDICAL RESEARCH FOUNDATION (United States)

d UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE; MEMAPSIN 2 INHIBITOR; OM 99 2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CRYSTAL STRUCTURE; MOLECULAR MODEL; NUCLEAR OVERHAUSER EFFECT; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENDOPEPTIDASES; HUMANS; MODELS, MOLECULAR; MOLECULAR WEIGHT; OLIGOPEPTIDES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035974650 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm0101803 Document Type: Article

Times cited : (236)

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