Structure of the protease domain of memapsin 2 (β-secretase) complexed with inhibitor

Science

Volumn 290, Issue 5489, 2000, Pages 150-153

  Hong, L ^a   Koelsch, G ^a   Lin, X ^a   Wu, S ^a   Terzyan, S ^a   Ghosh, A K ^a   Zhang, X C ^a   Tang, J ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BETA SECRETASE; PROTEINASE;

ALZHEIMER DISEASE; ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DEGENERATIVE DISEASE; ENZYME INHIBITOR COMPLEX; ENZYME STRUCTURE; HUMAN; NEUROLOGIC DISEASE; PRIORITY JOURNAL;

ASPARTIC ENDOPEPTIDASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMAN; HYDROGEN BONDING; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T;

EID: 0034613320     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.290.5489.150     Document Type: Article

References (36)