Design of substrate-based inhibitors of human β-secretase

Journal of Medicinal Chemistry

Volumn 45, Issue 2, 2002, Pages 259-262

  Tung, Jay S ^a   Davis, David L ^a   Anderson, John P ^a   Walker, Don E ^a   Mamo, Shumeye ^a   Jewett, Nancy ^a   Hom, Roy K ^a   Sinha, Sukanto ^a   Thorsett, Eugene D ^a   John, Varghese ^a  

^a ELAN PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA SECRETASE; BETA SECRETASE INHIBITOR; ENZYME INHIBITOR; STATINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; ENZYME SUBSTRATE; PROTEIN DEGRADATION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BRAIN; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0037122704     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0155695     Document Type: Article

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