β subunits of voltage-gated sodium channels are novel substrates of β-site amyloid precursor protein-cleaving enzyme (BACE1) and γ-secretase

Journal of Biological Chemistry

Volumn 280, Issue 24, 2005, Pages 23009-23017

  Wong, Hon Kit ^a   Sakurai, Takashi ^a   Oyama, Fumitaka ^a   Kaneko, Kumi ^a   Wada, Koji ^a   Miyazaki, Haruko ^a   Kurosawa, Masaru ^a   De Strooper, Bart ^b   Saftig, Paul ^c   Nukina, Nobuyuki ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASES; MOLECULAR BIOLOGY; PATHOLOGY; RNA; SODIUM; SUBSTRATES;

AMYLOID PRECURSOR PROTEIN (APP); ENZYME-SUBSTRATE INTERACTION; PROTEASES; SEQUENTIAL PROCESSING;

ENZYMES;

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 1; GAMMA SECRETASE; PRESENILIN 1; PRESENILIN 2; PROTEINASE; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA CHAIN; BRAIN; EMBRYO; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FIBROBLAST; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; RNA INTERFERENCE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; BLOTTING, WESTERN; BRAIN; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; DETERGENTS; ENDOPEPTIDASES; FIBROBLASTS; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NEURONS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION;

EID: 20744454142     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414648200     Document Type: Article

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