Rational design and synthesis of selective BACE-1 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 3, 2004, Pages 601-604

  Brady, Stephen F ^a   Singh, Satendra ^b   Crouthamel, Ming Chih ^a   Holloway, M Katharine ^a   Coburn, Craig A ^a   Garsky, Victor M ^a   Bogusky, Michael ^a   Pennington, Michael W ^b   Vacca, Joseph P ^a   Hazuda, Daria ^a   Lai, Ming Tain ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Bachem Holding AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA SECRETASE INHIBITOR; CATHEPSIN D; RENIN;

ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROPHOBICITY; MOLECULAR WEIGHT;

EID: 1642477688     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.11.061     Document Type: Article

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