Proliferation, survival and metabolism: The role of PI3K/AKT/ mTOR signalling in pluripotency and cell fate determination

Development (Cambridge)

Volumn 143, Issue 17, 2016, Pages 3050-3060

  Yu, Jason S L ^a   Cui, Wei ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

AKT; Metabolism; MTOR; PI3K; Pluripotency; Proliferation and differentiation

Indexed keywords

GLYCOLYTIC ENZYME; ISOPROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TARGET OF RAPAMYCIN KINASE;

CELL FATE; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; EMBRYO DEVELOPMENT; ENZYME METABOLISM; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SOMATIC CELL; ANIMAL; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PLURIPOTENT STEM CELLS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84984825559     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.137075     Document Type: Review

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