A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

Nature

Volumn 460, Issue 7251, 2009, Pages 118-122

  Niwa, Hitoshi ^a,b,c   Ogawa, Kazuya ^a   Shimosato, Daisuke ^a,b   Adachi, Kenjiro ^a  

^a RIKEN Center for Biosystems Dynamics Research   (Japan)

^b KOBE UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; STAT3 PROTEIN; TBX3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

CYTOLOGY; GENE EXPRESSION; RODENT; SIGNALING;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL ACTIVITY; CELL RENEWAL; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENE OVEREXPRESSION; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; JANUS KINASES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKEMIA INHIBITORY FACTOR; MAP KINASE SIGNALING SYSTEM; MICE; PLURIPOTENT STEM CELLS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; T-BOX DOMAIN PROTEINS;

EID: 67650032868     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08113     Document Type: Article

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