Functional compensation between Myc and PI3K signaling supports self-renewal of embryonic stem cells

Stem Cells

Volumn 33, Issue 3, 2015, Pages 713-725

  Hishida, Tomoaki ^a,b,c   Nakachi, Yutaka ^a   Mizuno, Yosuke ^a   Katano, Miyuki ^a   Okazaki, Yasushi ^a,b   Ema, Masatsugu ^d   Takahashi, Satoru ^b,d   Hirasaki, Masataka ^a   Suzuki, Ayumu ^a   Ueda, Atsushi ^a   Nishimoto, Masazumi ^a   Hishida Nozaki, Yuriko ^c   Vazquez Ferrer, Eric ^c   Sancho Martinez, Ignacio ^c   Carlos Izpisua Belmonte, Juan ^c   Okuda, Akihiko ^a,b  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Embryonic stem cells; MAPK; Myc; PI3K; Pluripotency

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; MAX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TRANSCRIPTION FACTOR NRF2; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; MAX PROTEIN, MOUSE; MYC PROTEIN, MOUSE; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; PLURIPOTENT STEM CELL;

MURINAE;

ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL PROLIFERATION; EMBRYONIC STEM CELLS; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; PHOSPHATIDYLINOSITOL 3-KINASES; PLURIPOTENT STEM CELLS; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 84923262042     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1893     Document Type: Article

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