메뉴 건너뛰기




Volumn 32, Issue 2, 2014, Pages 424-435

Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs

Author keywords

Cell culture; Cell signaling; Embryonic stem cells; Pluripotency

Indexed keywords

CELL CULTURE; CELL SIGNALING; EMBRYONIC STEM CELLS; PLURIPOTENCY;

EID: 84894601452     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1589     Document Type: Article
Times cited : (54)

References (40)
  • 2
    • 33750363298 scopus 로고    scopus 로고
    • The roles of intracellular protein-degradation pathways in neurodegeneration
    • Rubinsztein DC. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 2006;443: 780-786.
    • (2006) Nature , vol.443 , pp. 780-786
    • Rubinsztein, D.C.1
  • 3
    • 11244309014 scopus 로고    scopus 로고
    • Proteolysis: From the lysosome to ubiquitin and the proteasome
    • Ciechanover A. Proteolysis: From the lysosome to ubiquitin and the proteasome. Nat Rev Mol Cell Biol 2005;6: 79-87.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 79-87
    • Ciechanover, A.1
  • 4
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • Rabinowitz JD, White E. Autophagy and metabolism. Science 2010;330: 1344-1348.
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 5
    • 79954417611 scopus 로고    scopus 로고
    • Autophagy for tissue homeostasis and neuroprotection
    • Marino G, Madeo F, Kroemer G. Autophagy for tissue homeostasis and neuroprotection. Curr Opin Cell Biol 2011;23: 198-206.
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 198-206
    • Marino, G.1    Madeo, F.2    Kroemer, G.3
  • 6
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011;469: 323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 7
    • 77956416339 scopus 로고    scopus 로고
    • Autophagy in mammalian development and differentiation
    • Mizushima N, Levine B. Autophagy in mammalian development and differentiation. Nat Cell Biol 2010;12: 823-830.
    • (2010) Nat Cell Biol , vol.12 , pp. 823-830
    • Mizushima, N.1    Levine, B.2
  • 8
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008;132: 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 9
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005;122: 947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 10
    • 33746773659 scopus 로고    scopus 로고
    • Dissecting self-renewal in stem cells with rna interference
    • Ivanova N, Dobrin R, Lu R et al. Dissecting self-renewal in stem cells with RNA interference. Nature 2006;442: 533-538.
    • (2006) Nature , vol.442 , pp. 533-538
    • Ivanova, N.1    Dobrin, R.2    Lu, R.3
  • 11
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of oct-3/4 defines differentiation, dedifferentiation or self-renewal of es cells
    • Niwa H, Miyazaki J-I, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24: 372-376.
    • (2000) Nat Genet , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.-I.2    Smith, A.G.3
  • 12
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein nanog is required for mainte-nance of pluripotency in mouse epiblast and es cells
    • Mitsui K, Tokuzawa Y, Itoh H et al. The homeoprotein Nanog is required for mainte-nance of pluripotency in mouse epiblast and ES cells. Cell 2003;113: 631-642.
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3
  • 13
    • 84859539293 scopus 로고    scopus 로고
    • Distinct lineage specification roles for nanog, oct4, and sox2 in human embryonic stem cells
    • Wang Z, Oron E, Nelson B et al. Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells. Cell Stem Cell 2012;10: 440-454.
    • (2012) Cell Stem Cell , vol.10 , pp. 440-454
    • Wang, Z.1    Oron, E.2    Nelson, B.3
  • 14
    • 77949269474 scopus 로고    scopus 로고
    • Wwp2 mediates oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner
    • Liao B, Jin Y. Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner. Cell Res 2010; 20: 332-344.
    • (2010) Cell Res , vol.20 , pp. 332-344
    • Liao, B.1    Jin, Y.2
  • 15
    • 2542469858 scopus 로고    scopus 로고
    • Wwp2, an e3 ubiquitin ligase that targets transcription factor oct-4 for ubiquitination
    • Xu HM, Liao B, Zhang QJ et al. Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination. J Biol Chem 2004;279: 23495-23503.
    • (2004) J Biol Chem , vol.279 , pp. 23495-23503
    • Xu, H.M.1    Liao, B.2    Zhang, Q.J.3
  • 16
    • 67649097222 scopus 로고    scopus 로고
    • Wwp2 promotes degradation of transcription factor oct4 in human embryonic stem cells
    • Xu H, Wang W, Li C et al. WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells. Cell Res 2009;19: 561-573.
    • (2009) Cell Res , vol.19 , pp. 561-573
    • Xu, H.1    Wang, W.2    Li, C.3
  • 17
    • 33845645536 scopus 로고    scopus 로고
    • The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells
    • Szutorisz H, Georgiou A, Tora L et al. The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells. Cell 2006;127: 1375-1388.
    • (2006) Cell , vol.127 , pp. 1375-1388
    • Szutorisz, H.1    Georgiou, A.2    Tora, L.3
  • 18
    • 58849123232 scopus 로고    scopus 로고
    • A gene expression signature shared by human mature oocytes and embryonic stem cells
    • Assou S, Cerecedo D, Tondeur S et al. A gene expression signature shared by human mature oocytes and embryonic stem cells. BMC Genomics 2009;10: 10.
    • (2009) BMC Genomics , vol.10 , pp. 10
    • Assou, S.1    Cerecedo, D.2    Tondeur, S.3
  • 19
    • 84870945375 scopus 로고    scopus 로고
    • Regulation of pluripotency and cellular reprogramming by the ubiquitinproteasome system
    • Buckley Shannon M, Aranda-Orgilles B, Strikoudis A et al. Regulation of pluripotency and cellular reprogramming by the ubiquitinproteasome system. Cell Stem Cell 2012;11: 783-798.
    • (2012) Cell Stem Cell , vol.11 , pp. 783-798
    • Buckley Shannon, M.1    Aranda-Orgilles, B.2    Strikoudis, A.3
  • 20
    • 77950603770 scopus 로고    scopus 로고
    • Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mtor pathway and stimulating the bmp/smad pathway
    • Lee K-W, Yook J-Y, Son M-Y et al. Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway. Stem Cells Dev 2009;19: 557-568.
    • (2009) Stem Cells Dev , vol.19 , pp. 557-568
    • Lee, K.-W.1    Yook, J.-Y.2    Son, M.-Y.3
  • 21
    • 79960856255 scopus 로고    scopus 로고
    • Comprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cells
    • Fathi A, Hatami M, Hajihosseini V et al. Comprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cells. PLoS One 2011;6: e22856.
    • (2011) PLoS One , vol.6
    • Fathi, A.1    Hatami, M.2    Hajihosseini, V.3
  • 22
    • 66049149059 scopus 로고    scopus 로고
    • Mtor supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
    • Zhou J, Su P, Wang L et al. mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci USA 2009;106: 7840-7845.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7840-7845
    • Zhou, J.1    Su, P.2    Wang, L.3
  • 23
    • 78651469084 scopus 로고    scopus 로고
    • Evaluation of 28 human embryonic stem cell lines for use as unrelated donors in stem cell therapy: Implications of hla and abo genotypes
    • Lee JE, Kang MS, Park MH et al. Evaluation of 28 human embryonic stem cell lines for use as unrelated donors in stem cell therapy: Implications of HLA and ABO genotypes. Cell Transplant 2010;19: 1383-1395.
    • (2010) Cell Transplant , vol.19 , pp. 1383-1395
    • Lee, J.E.1    Kang, M.S.2    Park, M.H.3
  • 24
    • 84864293059 scopus 로고    scopus 로고
    • Variations in the epigenetic regulation of lineagespecific genes among human pluripotent stem cell lines
    • Kim H, Kim D, Jang M-J et al. Variations in the epigenetic regulation of lineagespecific genes among human pluripotent stem cell lines. Biochem Biophys Res Commun 2012;424: 331-337.
    • (2012) Biochem Biophys Res Commun , vol.424 , pp. 331-337
    • Kim, H.1    Kim, D.2    Jang, M.-J.3
  • 25
    • 33646033137 scopus 로고    scopus 로고
    • A lentiviral rnai library for human and mouse genes applied to an arrayed viral highcontent screen
    • Moffat J, Grueneberg DA, Yang X et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral highcontent screen. Cell 2006;124: 1283-1298.
    • (2006) Cell , vol.124 , pp. 1283-1298
    • Moffat, J.1    Grueneberg, D.A.2    Yang, X.3
  • 26
    • 0344375083 scopus 로고    scopus 로고
    • Lentivirus-delivered stable gene silencing by rnai in primary cells
    • Stewart SA, Dykxhoorn DM, Palliser D et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003;9: 493-501.
    • (2003) RNA , vol.9 , pp. 493-501
    • Stewart, S.A.1    Dykxhoorn, D.M.2    Palliser, D.3
  • 27
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010;140: 313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 28
    • 13744262804 scopus 로고    scopus 로고
    • Derivation and characterization of new human embryonic stem cell lines: Snuhes1, snuhes2, and snuhes3
    • Oh SK, Kim HS, Ahn HJ et al. Derivation and characterization of new human embryonic stem cell lines: SNUhES1, SNUhES2, and SNUhES3 Stem Cells 2005;23: 211-219.
    • (2005) Stem Cells , vol.23 , pp. 211-219
    • Oh, S.K.1    Kim, H.S.2    Ahn, H.J.3
  • 29
    • 84856618999 scopus 로고    scopus 로고
    • Autophagy is required for self-renewal and differentiation of adult human stem cells
    • Salemi S, Yousefi S, Constantinescu MA et al. Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell Res 2012;22: 432-435.
    • (2012) Cell Res , vol.22 , pp. 432-435
    • Salemi, S.1    Yousefi, S.2    Constantinescu, M.A.3
  • 30
    • 78649689953 scopus 로고    scopus 로고
    • Fip200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells
    • Liu F, Lee JY, Wei H et al. FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells. Blood 2010;116: 4806-4814.
    • (2010) Blood , vol.116 , pp. 4806-4814
    • Liu, F.1    Lee, J.Y.2    Wei, H.3
  • 31
    • 79952728102 scopus 로고    scopus 로고
    • The autophagy protein atg7 is essential for hematopoietic stem cell maintenance
    • Mortensen M, Soilleux EJ, Djordjevic G et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J Exp Med 2011;208: 455-467.
    • (2011) J Exp Med , vol.208 , pp. 455-467
    • Mortensen, M.1    Soilleux, E.J.2    Djordjevic, G.3
  • 32
    • 0842303313 scopus 로고    scopus 로고
    • Back to the future with ubiquitin
    • Pickart CM. Back to the future with ubiquitin. Cell 2004;116: 181-190.
    • (2004) Cell , vol.116 , pp. 181-190
    • Pickart, C.M.1
  • 33
    • 42049100859 scopus 로고    scopus 로고
    • Essential role of sequestosome 1/p62 in regulating accumulation of lys63-ubiquitinated proteins
    • Wooten MW, Geetha T, Babu JR et al. Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins. J Biol Chem 2008;283: 6783-6789.
    • (2008) J Biol Chem , vol.283 , pp. 6783-6789
    • Wooten, M.W.1    Geetha, T.2    Babu, J.R.3
  • 34
    • 77950487987 scopus 로고    scopus 로고
    • Mechanisms of cross-talk between the ubiquitin-proteasome and autophagylysosome systems
    • Korolchuk VI, Menzies FM, Rubinsztein DC. Mechanisms of cross-talk between the ubiquitin-proteasome and autophagylysosome systems. FEBS Lett 2010;584: 1393-1398.
    • (2010) FEBS Lett , vol.584 , pp. 1393-1398
    • Korolchuk, V.I.1    Menzies, F.M.2    Rubinsztein, D.C.3
  • 35
    • 34548299555 scopus 로고    scopus 로고
    • Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
    • Ding W-X, Ni H-M, Gao W et al. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007;171: 513-524.
    • (2007) Am J Pathol , vol.171 , pp. 513-524
    • Ding, W.-X.1    Ni, H.-M.2    Gao, W.3
  • 37
    • 41549114279 scopus 로고    scopus 로고
    • The role of autophagy-lysosome pathway in neurodegeneration associated with parkinson's disease
    • Pan T, Kondo S, Le W et al. The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain 2008;131: 1969-1978.
    • (2008) Brain , vol.131 , pp. 1969-1978
    • Pan, T.1    Kondo S Le, W.2
  • 38
    • 60549093730 scopus 로고    scopus 로고
    • Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates
    • Korolchuk VI, Mansilla A, Menzies FM et al. Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates. Mol Cell 2009;33: 517-527.
    • (2009) Mol Cell , vol.33 , pp. 517-527
    • Korolchuk, V.I.1    Mansilla, A.2    Menzies, F.M.3
  • 39
    • 77956269672 scopus 로고    scopus 로고
    • A data integration approach to mapping oct4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells
    • Jung M, Peterson H, Chavez L et al. A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells. PLoS One 2010;5: e10709.
    • (2010) PLoS One , vol.5
    • Jung, M.1    Peterson, H.2    Chavez, L.3
  • 40
    • 77956509115 scopus 로고    scopus 로고
    • Oct4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres
    • Kristensen DM, Nielsen JE, Kalisz M et al. OCT4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres. Mol Hum Reprod 2010;16: 835-845.
    • (2010) Mol Hum Reprod , vol.16 , pp. 835-845
    • Kristensen, D.M.1    Nielsen, J.E.2    Kalisz, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.