Multiallelic Disruption of the rictor Gene in Mice Reveals that mTOR Complex 2 Is Essential for Fetal Growth and Viability

Developmental Cell

Volumn 11, Issue 4, 2006, Pages 583-589

  Shiota, Chiyo ^a   Woo, Jeong Taek ^a   Lindner, Jill ^a   Shelton, Kathy D ^a   Magnuson, Mark A ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DEVBIO; SIGNALING

Indexed keywords

GROWTH FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; RICTOR PROTEIN; SERINE; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO MORTALITY; EMBRYONIC STRUCTURES; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FETAL WELL BEING; FETUS; FETUS GROWTH; FETUS HYDROPS; FIBROBLAST; GENE DISRUPTION; GENE EXPRESSION; GENE TARGETING; INTRAUTERINE GROWTH RETARDATION; METABOLIC DISORDER; METABOLIC INHIBITION; MOUSE; NONHUMAN; PLACENTA DISORDER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACTINS; ALLELES; ANIMALS; CARRIER PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; EMBRYO; FETAL DEVELOPMENT; FETAL VIABILITY; FIBROBLASTS; GENE TARGETING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

MAMMALIA;

EID: 33748950810     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2006.08.013     Document Type: Article

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