-
1
-
-
75149183235
-
Xp11.2 translocation renal cell carcinoma
-
H.B. Armah, and A.V. Parwani Xp11.2 translocation renal cell carcinoma Arch. Pathol. Lab. Med. 134 2010 124 129
-
(2010)
Arch. Pathol. Lab. Med.
, vol.134
, pp. 124-129
-
-
Armah, H.B.1
Parwani, A.V.2
-
2
-
-
33750293584
-
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
-
M. Baba, S.B. Hong, N. Sharma, M.B. Warren, M.L. Nickerson, A. Iwamatsu, D. Esposito, W.K. Gillette, R.F. Hopkins 3rd, and J.L. Hartley Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Proc. Natl. Acad. Sci. USA 103 2006 15552 15557
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15552-15557
-
-
Baba, M.1
Hong, S.B.2
Sharma, N.3
Warren, M.B.4
Nickerson, M.L.5
Iwamatsu, A.6
Esposito, D.7
Gillette, W.K.8
Hopkins III, R.F.9
Hartley, J.L.10
-
3
-
-
84865190528
-
The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development
-
M. Baba, J.R. Keller, H.W. Sun, W. Resch, S. Kuchen, H.C. Suh, H. Hasumi, Y. Hasumi, K.R. Kieffer-Kwon, and C.G. Gonzalez The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development Blood 120 2012 1254 1261
-
(2012)
Blood
, vol.120
, pp. 1254-1261
-
-
Baba, M.1
Keller, J.R.2
Sun, H.W.3
Resch, W.4
Kuchen, S.5
Suh, H.C.6
Hasumi, H.7
Hasumi, Y.8
Kieffer-Kwon, K.R.9
Gonzalez, C.G.10
-
4
-
-
0032808135
-
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
-
M. Brannon, J.D. Brown, R. Bates, D. Kimelman, and R.T. Moon XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development Development 126 1999 3159 3170
-
(1999)
Development
, vol.126
, pp. 3159-3170
-
-
Brannon, M.1
Brown, J.D.2
Bates, R.3
Kimelman, D.4
Moon, R.T.5
-
5
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
I.G. Brons, L.E. Smithers, M.W. Trotter, P. Rugg-Gunn, B. Sun, S.M. Chuva de Sousa Lopes, S.K. Howlett, A. Clarkson, L. Ahrlund-Richter, R.A. Pedersen, and L. Vallier Derivation of pluripotent epiblast stem cells from mammalian embryos Nature 448 2007 191 195
-
(2007)
Nature
, vol.448
, pp. 191-195
-
-
Brons, I.G.1
Smithers, L.E.2
Trotter, M.W.3
Rugg-Gunn, P.4
Sun, B.5
Chuva De Sousa Lopes, S.M.6
Howlett, S.K.7
Clarkson, A.8
Ahrlund-Richter, L.9
Pedersen, R.A.10
Vallier, L.11
-
6
-
-
77956325165
-
The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development
-
H. Chanut-Delalande, A.C. Jung, M.M. Baer, L. Lin, F. Payre, and M. Affolter The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development PLoS ONE 5 2010 e10245
-
(2010)
PLoS ONE
, vol.5
, pp. 10245
-
-
Chanut-Delalande, H.1
Jung, A.C.2
Baer, M.M.3
Lin, L.4
Payre, F.5
Affolter, M.6
-
7
-
-
55849108854
-
Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia
-
J. Chen, K. Futami, D. Petillo, J. Peng, P. Wang, J. Knol, Y. Li, S.K. Khoo, D. Huang, and C.N. Qian Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia PLoS ONE 3 2008 e3581
-
(2008)
PLoS ONE
, vol.3
, pp. 3581
-
-
Chen, J.1
Futami, K.2
Petillo, D.3
Peng, J.4
Wang, P.5
Knol, J.6
Li, Y.7
Khoo, S.K.8
Huang, D.9
Qian, C.N.10
-
8
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
X. Chen, H. Xu, P. Yuan, F. Fang, M. Huss, V.B. Vega, E. Wong, Y.L. Orlov, W. Zhang, and J. Jiang Integration of external signaling pathways with the core transcriptional network in embryonic stem cells Cell 133 2008 1106 1117
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
-
9
-
-
34249311572
-
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
-
B.W. Doble, S. Patel, G.A. Wood, L.K. Kockeritz, and J.R. Woodgett Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines Dev. Cell 12 2007 957 971
-
(2007)
Dev. Cell
, vol.12
, pp. 957-971
-
-
Doble, B.W.1
Patel, S.2
Wood, G.A.3
Kockeritz, L.K.4
Woodgett, J.R.5
-
10
-
-
84867381511
-
Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells
-
N. Festuccia, R. Osorno, F. Halbritter, V. Karwacki-Neisius, P. Navarro, D. Colby, F. Wong, A. Yates, S.R. Tomlinson, and I. Chambers Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells Cell Stem Cell 11 2012 477 490
-
(2012)
Cell Stem Cell
, vol.11
, pp. 477-490
-
-
Festuccia, N.1
Osorno, R.2
Halbritter, F.3
Karwacki-Neisius, V.4
Navarro, P.5
Colby, D.6
Wong, F.7
Yates, A.8
Tomlinson, S.R.9
Chambers, I.10
-
11
-
-
66049136895
-
Klf4 reverts developmentally programmed restriction of ground state pluripotency
-
G. Guo, J. Yang, J. Nichols, J.S. Hall, I. Eyres, W. Mansfield, and A. Smith Klf4 reverts developmentally programmed restriction of ground state pluripotency Development 136 2009 1063 1069
-
(2009)
Development
, vol.136
, pp. 1063-1069
-
-
Guo, G.1
Yang, J.2
Nichols, J.3
Hall, J.S.4
Eyres, I.5
Mansfield, W.6
Smith, A.7
-
12
-
-
64049090204
-
The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis
-
T.R. Hartman, E. Nicolas, A. Klein-Szanto, T. Al-Saleem, T.P. Cash, M.C. Simon, and E.P. Henske The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis Oncogene 28 2009 1594 1604
-
(2009)
Oncogene
, vol.28
, pp. 1594-1604
-
-
Hartman, T.R.1
Nicolas, E.2
Klein-Szanto, A.3
Al-Saleem, T.4
Cash, T.P.5
Simon, M.C.6
Henske, E.P.7
-
13
-
-
42649092576
-
Identification and characterization of a novel folliculin-interacting protein FNIP2
-
H. Hasumi, M. Baba, S.B. Hong, Y. Hasumi, Y. Huang, M. Yao, V.A. Valera, W.M. Linehan, and L.S. Schmidt Identification and characterization of a novel folliculin-interacting protein FNIP2 Gene 415 2008 60 67
-
(2008)
Gene
, vol.415
, pp. 60-67
-
-
Hasumi, H.1
Baba, M.2
Hong, S.B.3
Hasumi, Y.4
Huang, Y.5
Yao, M.6
Valera, V.A.7
Linehan, W.M.8
Schmidt, L.S.9
-
14
-
-
73249138930
-
Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2
-
Y. Hasumi, M. Baba, R. Ajima, H. Hasumi, V.A. Valera, M.E. Klein, D.C. Haines, M.J. Merino, S.B. Hong, and T.P. Yamaguchi Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2 Proc. Natl. Acad. Sci. USA 106 2009 18722 18727
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 18722-18727
-
-
Hasumi, Y.1
Baba, M.2
Ajima, R.3
Hasumi, H.4
Valera, V.A.5
Klein, M.E.6
Haines, D.C.7
Merino, M.J.8
Hong, S.B.9
Yamaguchi, T.P.10
-
15
-
-
80052022935
-
Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells
-
K. Hayashi, H. Ohta, K. Kurimoto, S. Aramaki, and M. Saitou Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells Cell 146 2011 519 532
-
(2011)
Cell
, vol.146
, pp. 519-532
-
-
Hayashi, K.1
Ohta, H.2
Kurimoto, K.3
Aramaki, S.4
Saitou, M.5
-
16
-
-
0028062014
-
Microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family
-
T.J. Hemesath, E. Steingrímsson, G. McGill, M.J. Hansen, J. Vaught, C.A. Hodgkinson, H. Arnheiter, N.G. Copeland, N.A. Jenkins, and D.E. Fisher microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family Genes Dev. 8 1994 2770 2780
-
(1994)
Genes Dev.
, vol.8
, pp. 2770-2780
-
-
Hemesath, T.J.1
Steingrímsson, E.2
McGill, G.3
Hansen, M.J.4
Vaught, J.5
Hodgkinson, C.A.6
Arnheiter, H.7
Copeland, N.G.8
Jenkins, N.A.9
Fisher, D.E.10
-
17
-
-
78650839179
-
Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization
-
S.B. Hong, H. Oh, V.A. Valera, M. Baba, L.S. Schmidt, and W.M. Linehan Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization PLoS ONE 5 2010 e15793
-
(2010)
PLoS ONE
, vol.5
, pp. 15793
-
-
Hong, S.B.1
Oh, H.2
Valera, V.A.3
Baba, M.4
Schmidt, L.S.5
Linehan, W.M.6
-
18
-
-
34447568404
-
Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity
-
C. Huan, M.L. Kelly, R. Steele, I. Shapira, S.R. Gottesman, and C.A. Roman Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity Nat. Immunol. 7 2006 1082 1091
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1082-1091
-
-
Huan, C.1
Kelly, M.L.2
Steele, R.3
Shapira, I.4
Gottesman, S.R.5
Roman, C.A.6
-
19
-
-
33746773659
-
Dissecting self-renewal in stem cells with RNA interference
-
N. Ivanova, R. Dobrin, R. Lu, I. Kotenko, J. Levorse, C. DeCoste, X. Schafer, Y. Lun, and I.R. Lemischka Dissecting self-renewal in stem cells with RNA interference Nature 442 2006 533 538
-
(2006)
Nature
, vol.442
, pp. 533-538
-
-
Ivanova, N.1
Dobrin, R.2
Lu, R.3
Kotenko, I.4
Levorse, J.5
Decoste, C.6
Schafer, X.7
Lun, Y.8
Lemischka, I.R.9
-
20
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
R. Jaenisch, and R. Young Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming Cell 132 2008 567 582
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
21
-
-
33644764030
-
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
-
K. Kaji, I.M. Caballero, R. MacLeod, J. Nichols, V.A. Wilson, and B. Hendrich The NuRD component Mbd3 is required for pluripotency of embryonic stem cells Nat. Cell Biol. 8 2006 285 292
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 285-292
-
-
Kaji, K.1
Caballero, I.M.2
MacLeod, R.3
Nichols, J.4
Wilson, V.A.5
Hendrich, B.6
-
22
-
-
0033559663
-
Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice
-
T. Kobayashi, O. Minowa, J. Kuno, H. Mitani, O. Hino, and T. Noda Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice Cancer Res. 59 1999 1206 1211
-
(1999)
Cancer Res.
, vol.59
, pp. 1206-1211
-
-
Kobayashi, T.1
Minowa, O.2
Kuno, J.3
Mitani, H.4
Hino, O.5
Noda, T.6
-
23
-
-
0035902509
-
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice
-
T. Kobayashi, O. Minowa, Y. Sugitani, S. Takai, H. Mitani, E. Kobayashi, T. Noda, and O. Hino A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice Proc. Natl. Acad. Sci. USA 98 2001 8762 8767
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 8762-8767
-
-
Kobayashi, T.1
Minowa, O.2
Sugitani, Y.3
Takai, S.4
Mitani, H.5
Kobayashi, E.6
Noda, T.7
Hino, O.8
-
24
-
-
34548587064
-
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
-
T. Kunath, M.K. Saba-El-Leil, M. Almousailleakh, J. Wray, S. Meloche, and A. Smith FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment Development 134 2007 2895 2902
-
(2007)
Development
, vol.134
, pp. 2895-2902
-
-
Kunath, T.1
Saba-El-Leil, M.K.2
Almousailleakh, M.3
Wray, J.4
Meloche, S.5
Smith, A.6
-
25
-
-
77149130955
-
Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state
-
F. Lanner, K.L. Lee, M. Sohl, K. Holmborn, H. Yang, J. Wilbertz, L. Poellinger, J. Rossant, and F. Farnebo Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state Stem Cells 28 2010 191 200
-
(2010)
Stem Cells
, vol.28
, pp. 191-200
-
-
Lanner, F.1
Lee, K.L.2
Sohl, M.3
Holmborn, K.4
Yang, H.5
Wilbertz, J.6
Poellinger, L.7
Rossant, J.8
Farnebo, F.9
-
26
-
-
84859778293
-
MTOR signaling in growth control and disease
-
M. Laplante, and D.M. Sabatini mTOR signaling in growth control and disease Cell 149 2012 274 293
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
27
-
-
77952263737
-
The genetic basis of kidney cancer: A metabolic disease
-
W.M. Linehan, R. Srinivasan, and L.S. Schmidt The genetic basis of kidney cancer: a metabolic disease Nat Rev Urol 7 2010 277 285
-
(2010)
Nat Rev Urol
, vol.7
, pp. 277-285
-
-
Linehan, W.M.1
Srinivasan, R.2
Schmidt, L.S.3
-
28
-
-
84860351082
-
The transcriptional and epigenomic foundations of ground state pluripotency
-
H. Marks, T. Kalkan, R. Menafra, S. Denissov, K. Jones, H. Hofemeister, J. Nichols, A. Kranz, A.F. Stewart, A. Smith, and H.G. Stunnenberg The transcriptional and epigenomic foundations of ground state pluripotency Cell 149 2012 590 604
-
(2012)
Cell
, vol.149
, pp. 590-604
-
-
Marks, H.1
Kalkan, T.2
Menafra, R.3
Denissov, S.4
Jones, K.5
Hofemeister, H.6
Nichols, J.7
Kranz, A.8
Stewart, A.F.9
Smith, A.10
Stunnenberg, H.G.11
-
29
-
-
84867387161
-
Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
-
G. Martello, T. Sugimoto, E. Diamanti, A. Joshi, R. Hannah, S. Ohtsuka, B. Göttgens, H. Niwa, and A. Smith Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal Cell Stem Cell 11 2012 491 504
-
(2012)
Cell Stem Cell
, vol.11
, pp. 491-504
-
-
Martello, G.1
Sugimoto, T.2
Diamanti, E.3
Joshi, A.4
Hannah, R.5
Ohtsuka, S.6
Göttgens, B.7
Niwa, H.8
Smith, A.9
-
30
-
-
0842344619
-
Tcf3: A transcriptional regulator of axis induction in the early embryo
-
B.J. Merrill, H.A. Pasolli, L. Polak, M. Rendl, M.J. García- García, K.V. Anderson, and E. Fuchs Tcf3: a transcriptional regulator of axis induction in the early embryo Development 131 2004 263 274
-
(2004)
Development
, vol.131
, pp. 263-274
-
-
Merrill, B.J.1
Pasolli, H.A.2
Polak, L.3
Rendl, M.4
García-García, M.J.5
Anderson, K.V.6
Fuchs, E.7
-
31
-
-
1642515793
-
Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma
-
A.J. Miller, J. Du, S. Rowan, C.L. Hershey, H.R. Widlund, and D.E. Fisher Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma Cancer Res. 64 2004 509 516
-
(2004)
Cancer Res.
, vol.64
, pp. 509-516
-
-
Miller, A.J.1
Du, J.2
Rowan, S.3
Hershey, C.L.4
Widlund, H.R.5
Fisher, D.E.6
-
32
-
-
66049117813
-
Naive and primed pluripotent states
-
J. Nichols, and A. Smith Naive and primed pluripotent states Cell Stem Cell 4 2009 487 492
-
(2009)
Cell Stem Cell
, vol.4
, pp. 487-492
-
-
Nichols, J.1
Smith, A.2
-
33
-
-
78650730724
-
The origin and identity of embryonic stem cells
-
J. Nichols, and A. Smith The origin and identity of embryonic stem cells Development 138 2011 3 8
-
(2011)
Development
, vol.138
, pp. 3-8
-
-
Nichols, J.1
Smith, A.2
-
35
-
-
0000939691
-
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome
-
M.L. Nickerson, M.B. Warren, J.R. Toro, V. Matrosova, G. Glenn, M.L. Turner, P. Duray, M. Merino, P. Choyke, and C.P. Pavlovich Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome Cancer Cell 2 2002 157 164
-
(2002)
Cancer Cell
, vol.2
, pp. 157-164
-
-
Nickerson, M.L.1
Warren, M.B.2
Toro, J.R.3
Matrosova, V.4
Glenn, G.5
Turner, M.L.6
Duray, P.7
Merino, M.8
Choyke, P.9
Pavlovich, C.P.10
-
36
-
-
67650032868
-
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
-
H. Niwa, K. Ogawa, D. Shimosato, and K. Adachi A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells Nature 460 2009 118 122
-
(2009)
Nature
, vol.460
, pp. 118-122
-
-
Niwa, H.1
Ogawa, K.2
Shimosato, D.3
Adachi, K.4
-
37
-
-
84861455990
-
Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development
-
H. Park, K. Staehling, M. Tsang, M.W. Appleby, M.E. Brunkow, D. Margineantu, D.M. Hockenbery, T. Habib, H.D. Liggitt, G. Carlson, and B.M. Iritani Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development Immunity 36 2012 769 781
-
(2012)
Immunity
, vol.36
, pp. 769-781
-
-
Park, H.1
Staehling, K.2
Tsang, M.3
Appleby, M.W.4
Brunkow, M.E.5
Margineantu, D.6
Hockenbery, D.M.7
Habib, T.8
Liggitt, H.D.9
Carlson, G.10
Iritani, B.M.11
-
38
-
-
84867728827
-
Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming
-
M. Percharde, F. Lavial, J.H. Ng, V. Kumar, R.A. Tomaz, N. Martin, J.C. Yeo, J. Gil, S. Prabhakar, and H.H. Ng Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming Genes Dev. 26 2012 2286 2298
-
(2012)
Genes Dev.
, vol.26
, pp. 2286-2298
-
-
Percharde, M.1
Lavial, F.2
Ng, J.H.3
Kumar, V.4
Tomaz, R.A.5
Martin, N.6
Yeo, J.C.7
Gil, J.8
Prabhakar, S.9
Ng, H.H.10
-
39
-
-
33749645068
-
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
-
L. Pereira, F. Yi, and B.J. Merrill Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal Mol. Cell. Biol. 26 2006 7479 7491
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7479-7491
-
-
Pereira, L.1
Yi, F.2
Merrill, B.J.3
-
40
-
-
70349092228
-
Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway
-
X. Piao, T. Kobayashi, L. Wang, M. Shiono, Y. Takagi, G. Sun, M. Abe, Y. Hagiwara, D. Zhang, and K. Okimoto Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway Biochem. Biophys. Res. Commun. 389 2009 16 21
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.389
, pp. 16-21
-
-
Piao, X.1
Kobayashi, T.2
Wang, L.3
Shiono, M.4
Takagi, Y.5
Sun, G.6
Abe, M.7
Hagiwara, Y.8
Zhang, D.9
Okimoto, K.10
-
41
-
-
68749110887
-
Nanog is the gateway to the pluripotent ground state
-
J. Silva, J. Nichols, T.W. Theunissen, G. Guo, A.L. van Oosten, O. Barrandon, J. Wray, S. Yamanaka, I. Chambers, and A. Smith Nanog is the gateway to the pluripotent ground state Cell 138 2009 722 737
-
(2009)
Cell
, vol.138
, pp. 722-737
-
-
Silva, J.1
Nichols, J.2
Theunissen, T.W.3
Guo, G.4
Van Oosten, A.L.5
Barrandon, O.6
Wray, J.7
Yamanaka, S.8
Chambers, I.9
Smith, A.10
-
42
-
-
0037007031
-
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development
-
E. Steingrimsson, L. Tessarollo, B. Pathak, L. Hou, H. Arnheiter, N.G. Copeland, and N.A. Jenkins Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development Proc. Natl. Acad. Sci. USA 99 2002 4477 4482
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4477-4482
-
-
Steingrimsson, E.1
Tessarollo, L.2
Pathak, B.3
Hou, L.4
Arnheiter, H.5
Copeland, N.G.6
Jenkins, N.A.7
-
43
-
-
51649122895
-
Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein
-
Y. Takagi, T. Kobayashi, M. Shiono, L. Wang, X. Piao, G. Sun, D. Zhang, M. Abe, Y. Hagiwara, K. Takahashi, and O. Hino Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein Oncogene 27 2008 5339 5347
-
(2008)
Oncogene
, vol.27
, pp. 5339-5347
-
-
Takagi, Y.1
Kobayashi, T.2
Shiono, M.3
Wang, L.4
Piao, X.5
Sun, G.6
Zhang, D.7
Abe, M.8
Hagiwara, Y.9
Takahashi, K.10
Hino, O.11
-
44
-
-
77956412152
-
Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis
-
F. Tang, C. Barbacioru, S. Bao, C. Lee, E. Nordman, X. Wang, K. Lao, and M.A. Surani Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis Cell Stem Cell 6 2010 468 478
-
(2010)
Cell Stem Cell
, vol.6
, pp. 468-478
-
-
Tang, F.1
Barbacioru, C.2
Bao, S.3
Lee, C.4
Nordman, E.5
Wang, X.6
Lao, K.7
Surani, M.A.8
-
45
-
-
73649097906
-
Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2
-
H.P. Tarleton, and I.R. Lemischka Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2 Mech. Dev. 127 2010 107 119
-
(2010)
Mech. Dev.
, vol.127
, pp. 107-119
-
-
Tarleton, H.P.1
Lemischka, I.R.2
-
46
-
-
0036899420
-
Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction
-
D. Teis, W. Wunderlich, and L.A. Huber Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction Dev. Cell 3 2002 803 814
-
(2002)
Dev. Cell
, vol.3
, pp. 803-814
-
-
Teis, D.1
Wunderlich, W.2
Huber, L.A.3
-
47
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
P.J. Tesar, J.G. Chenoweth, F.A. Brook, T.J. Davies, E.P. Evans, D.L. Mack, R.L. Gardner, and R.D. McKay New cell lines from mouse epiblast share defining features with human embryonic stem cells Nature 448 2007 196 199
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
MacK, D.L.6
Gardner, R.L.7
McKay, R.D.8
-
48
-
-
84855495451
-
A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation
-
B.A. Westerman, A.K. Braat, N. Taub, M. Potman, J.H. Vissers, M. Blom, E. Verhoeven, H. Stoop, A. Gillis, and A. Velds A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation J. Exp. Med. 208 2011 2675 2689
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2675-2689
-
-
Westerman, B.A.1
Braat, A.K.2
Taub, N.3
Potman, M.4
Vissers, J.H.5
Blom, M.6
Verhoeven, E.7
Stoop, H.8
Gillis, A.9
Velds, A.10
-
50
-
-
79959950773
-
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
-
J. Wray, T. Kalkan, S. Gomez-Lopez, D. Eckardt, A. Cook, R. Kemler, and A. Smith Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation Nat. Cell Biol. 13 2011 838 845
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 838-845
-
-
Wray, J.1
Kalkan, T.2
Gomez-Lopez, S.3
Eckardt, D.4
Cook, A.5
Kemler, R.6
Smith, A.7
-
51
-
-
77956199358
-
Stat3 activation is limiting for reprogramming to ground state pluripotency
-
J. Yang, A.L. van Oosten, T.W. Theunissen, G. Guo, J.C. Silva, and A. Smith Stat3 activation is limiting for reprogramming to ground state pluripotency Cell Stem Cell 7 2010 319 328
-
(2010)
Cell Stem Cell
, vol.7
, pp. 319-328
-
-
Yang, J.1
Van Oosten, A.L.2
Theunissen, T.W.3
Guo, G.4
Silva, J.C.5
Smith, A.6
-
52
-
-
84872028640
-
A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation
-
S.H. Yang, T. Kalkan, C. Morrisroe, A. Smith, and A.D. Sharrocks A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation PLoS Genet. 8 2012 e1003112
-
(2012)
PLoS Genet.
, vol.8
, pp. 1003112
-
-
Yang, S.H.1
Kalkan, T.2
Morrisroe, C.3
Smith, A.4
Sharrocks, A.D.5
-
53
-
-
0037313844
-
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
-
Q.L. Ying, M. Stavridis, D. Griffiths, M. Li, and A. Smith Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture Nat. Biotechnol. 21 2003 183 186
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 183-186
-
-
Ying, Q.L.1
Stavridis, M.2
Griffiths, D.3
Li, M.4
Smith, A.5
-
54
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Q.L. Ying, J. Wray, J. Nichols, L. Batlle-Morera, B. Doble, J. Woodgett, P. Cohen, and A. Smith The ground state of embryonic stem cell self-renewal Nature 453 2008 519 523
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
Batlle-Morera, L.4
Doble, B.5
Woodgett, J.6
Cohen, P.7
Smith, A.8
-
55
-
-
33750293584
-
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
-
M. Baba, S.B. Hong, N. Sharma, M.B. Warren, M.L. Nickerson, A. Iwamatsu, D. Esposito, W.K. Gillette, R.F. Hopkins 3rd, and J.L. Hartley Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Proc. Natl. Acad. Sci. USA 103 2006 15552 15557
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15552-15557
-
-
Baba, M.1
Hong, S.B.2
Sharma, N.3
Warren, M.B.4
Nickerson, M.L.5
Iwamatsu, A.6
Esposito, D.7
Gillette, W.K.8
Hopkins III, R.F.9
Hartley, J.L.10
-
56
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
X. Chen, H. Xu, P. Yuan, F. Fang, M. Huss, V.B. Vega, E. Wong, Y.L. Orlov, W. Zhang, and J. Jiang Integration of external signaling pathways with the core transcriptional network in embryonic stem cells Cell 133 2008 1106 1117
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
-
57
-
-
66049136895
-
Klf4 reverts developmentally programmed restriction of ground state pluripotency
-
G. Guo, J. Yang, J. Nichols, J.S. Hall, I. Eyres, W. Mansfield, and A. Smith Klf4 reverts developmentally programmed restriction of ground state pluripotency Development 136 2009 1063 1069
-
(2009)
Development
, vol.136
, pp. 1063-1069
-
-
Guo, G.1
Yang, J.2
Nichols, J.3
Hall, J.S.4
Eyres, I.5
Mansfield, W.6
Smith, A.7
-
58
-
-
34147197561
-
Gene function in early mouse embryonic stem cell differentiation
-
K. Hailesellasse Sene, C.J. Porter, G. Palidwor, C. Perez-Iratxeta, E.M. Muro, P.A. Campbell, M.A. Rudnicki, and M.A. Andrade-Navarro Gene function in early mouse embryonic stem cell differentiation BMC Genomics 8 2007 85
-
(2007)
BMC Genomics
, vol.8
, pp. 85
-
-
Hailesellasse Sene, K.1
Porter, C.J.2
Palidwor, G.3
Perez-Iratxeta, C.4
Muro, E.M.5
Campbell, P.A.6
Rudnicki, M.A.7
Andrade-Navarro, M.A.8
-
59
-
-
73249138930
-
Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2
-
Y. Hasumi, M. Baba, R. Ajima, H. Hasumi, V.A. Valera, M.E. Klein, D.C. Haines, M.J. Merino, S.B. Hong, and T.P. Yamaguchi Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2 Proc. Natl. Acad. Sci. USA 106 2009 18722 18727
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 18722-18727
-
-
Hasumi, Y.1
Baba, M.2
Ajima, R.3
Hasumi, H.4
Valera, V.A.5
Klein, M.E.6
Haines, D.C.7
Merino, M.J.8
Hong, S.B.9
Yamaguchi, T.P.10
-
60
-
-
48449084118
-
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
-
A. Marson, S.S. Levine, M.F. Cole, G.M. Frampton, T. Brambrink, S. Johnstone, M.G. Guenther, W.K. Johnston, M. Wernig, and J. Newman Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells Cell 134 2008 521 533
-
(2008)
Cell
, vol.134
, pp. 521-533
-
-
Marson, A.1
Levine, S.S.2
Cole, M.F.3
Frampton, G.M.4
Brambrink, T.5
Johnstone, S.6
Guenther, M.G.7
Johnston, W.K.8
Wernig, M.9
Newman, J.10
-
61
-
-
84867387161
-
Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
-
G. Martello, T. Sugimoto, E. Diamanti, A. Joshi, R. Hannah, S. Ohtsuka, B. Göttgens, H. Niwa, and A. Smith Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal Cell Stem Cell 11 2012 491 504
-
(2012)
Cell Stem Cell
, vol.11
, pp. 491-504
-
-
Martello, G.1
Sugimoto, T.2
Diamanti, E.3
Joshi, A.4
Hannah, R.5
Ohtsuka, S.6
Göttgens, B.7
Niwa, H.8
Smith, A.9
-
62
-
-
70349934958
-
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
-
J. Nichols, J. Silva, M. Roode, and A. Smith Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo Development 136 2009 3215 3222
-
(2009)
Development
, vol.136
, pp. 3215-3222
-
-
Nichols, J.1
Silva, J.2
Roode, M.3
Smith, A.4
-
63
-
-
77956199358
-
Stat3 activation is limiting for reprogramming to ground state pluripotency
-
J. Yang, A.L. van Oosten, T.W. Theunissen, G. Guo, J.C. Silva, and A. Smith Stat3 activation is limiting for reprogramming to ground state pluripotency Cell Stem Cell 7 2010 319 328
-
(2010)
Cell Stem Cell
, vol.7
, pp. 319-328
-
-
Yang, J.1
Van Oosten, A.L.2
Theunissen, T.W.3
Guo, G.4
Silva, J.C.5
Smith, A.6
|