A crucial role for the p110δ subunit of phosphatidylinositol 3-kinase in B cell development and activation

Journal of Experimental Medicine

Volumn 196, Issue 6, 2002, Pages 753-763

  Clayton, Elizabeth ^a   Bardi, Giuseppe ^a   Bell, Sarah E ^a   Chantry, David ^b   Peter Downes, C ^c   Gray, Alexander ^c   Humphries, Lisa A ^d   Rawlings, David ^e   Reynolds, Helen ^a   Vigorito, Elena ^a   Turner, Martin ^e,f  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b SonoSite Inc   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f Lymphocyte Signaling and Development Laboratory   (United Kingdom)

Author keywords

Akt; Btk; Calcium; Gene targeting; p110

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD40 ANTIGEN; DNA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; POLYCLONAL ANTIBODY; PROTEIN KINASE B; AGAMMAGLOBULINAEMIA TYROSINE KINASE; CALCIUM; ISOENZYME; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; PHOSPHOLIPASE C GAMMA; POLYPHOSPHOINOSITIDE; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANTIBODY RESPONSE; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; ENZYME SUBUNIT; GENE TARGETING; IMMUNOPRECIPITATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ANTIBODY PRODUCTION; BIOSYNTHESIS; MALE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; CALCIUM; ISOENZYMES; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ANTIGEN, B-CELL;

EID: 0037119630     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020805     Document Type: Article

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