Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 12, 2012, Pages 4485-4490

  Davidson, Kathryn C ^a   Adams, Allison M ^a   Goodson, Jamie M ^a   McDonald, Circe E ^a   Potter, Jennifer C ^a   Berndt, Jason D ^a   Biechele, Travis L ^a   Taylor, Russell J ^a   Moon, Randall T ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CD9 ANTIGEN; LIGAND; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; WNT PROTEIN; WNT3A PROTEIN;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL EXPANSION; CELL SELECTION; CELL STIMULATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MESODERM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BETA CATENIN; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; COCULTURE TECHNIQUES; EMBRYONIC STEM CELLS; GENES, REPORTER; HUMANS; MICE; MODELS, BIOLOGICAL; OCTAMER TRANSCRIPTION FACTOR-3; SIGNAL TRANSDUCTION; WNT PROTEINS;

VERTEBRATA;

EID: 84858684478     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118777109     Document Type: Article

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