Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming

Nature Cell Biology

Volumn 17, Issue 6, 2015, Pages 715-725

  Wu, Yasong ^a   Li, Yuan ^a,b   Zhang, Hui ^a   Huang, Yinghua ^a   Zhao, Ping ^a   Tang, Yujia ^a   Qiu, Xiaohui ^a   Ying, Yue ^a   Li, Wen ^c,d   Ni, Su ^a   Zhang, Meng ^a,e   Liu, Longqi ^a   Xu, Yan ^a   Zhuang, Qiang ^a   Luo, Zhiwei ^a   Benda, Christina ^a   Song, Hong ^a   Liu, Baohua ^f   Lai, Liangxue ^a   Liu, Xingguo ^a   Tse, Hung Fat ^c,g   Bao, Xichen ^a   Chan, Wai Yee ^h   Esteban, Miguel A ^a,h   Qin, Baoming ^a,c   Pei, Duanqing ^a,c   more..

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e ANHUI UNIVERSITY   (China)

^f Shenzhen University   (China)

^g UNIVERSITY OF HONG KONG   (China)

^h CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; BECLIN 1; KRUPPEL LIKE FACTOR 4; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P53; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; ATG5 PROTEIN, MOUSE; BECN1 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; MYC PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3 KINASE; POU5F1 PROTEIN, MOUSE; SMALL INTERFERING RNA; SOX2 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR SOX;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATG5 GENE; AUTOPHAGY; BECN1 GENE; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENE; GENE CONTROL; GENE FUNCTION; GENE INDUCTION; GENE SILENCING; KLF4 GENE; MITOCHONDRIAL REMODELLING; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SOMATIC CELL; ULK1 GENE; UPREGULATION; VPS34 GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DOWN REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; RNA INTERFERENCE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELLS, CULTURED; CELLULAR REPROGRAMMING; CLASS III PHOSPHATIDYLINOSITOL 3-KINASES; DOWN-REGULATION; FIBROBLASTS; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; OCTAMER TRANSCRIPTION FACTOR-3; PROTO-ONCOGENE PROTEINS C-MYC; RNA INTERFERENCE; RNA, SMALL INTERFERING; SOXB1 TRANSCRIPTION FACTORS; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84930178496     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3172     Document Type: Article

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